Universal Vector Driven Tester (VDT)

Seung Y. “Daniel” Lee,Byunghwan Chun,Brian Y. Kim,Austin S. Kim 한국통신학회 2006 한국통신학회 학술대회논문집 Vol.2006 No.7

Flexible marginalized models for bivariate longitudinal ordinal data

Lee, Keunbaik,Daniels, Michael J.,Joo, Yongsung Oxford University Press 2013 Biostatistics Vol.14 No.3

<P>Random effects models are commonly used to analyze longitudinal categorical data. Marginalized random effects models are a class of models that permit direct estimation of marginal mean parameters and characterize serial correlation for longitudinal categorical data via random effects (Heagerty, 1999). Marginally specified logistic-normal models for longitudinal binary data. <I>Biometrics</I> <B>55</B>, 688–698; Lee and Daniels, 2008. Marginalized models for longitudinal ordinal data with application to quality of life studies. <I>Statistics in Medicine</I> <B>27</B>, 4359–4380). In this paper, we propose a Kronecker product (KP) covariance structure to capture the correlation between processes at a given time <I>and</I> the correlation within a process over time (serial correlation) for bivariate longitudinal ordinal data. For the latter, we consider a more general class of models than standard (first-order) autoregressive correlation models, by re-parameterizing the correlation matrix using partial autocorrelations (Daniels and Pourahmadi, 2009). Modeling covariance matrices via partial autocorrelations. <I>Journal of Multivariate Analysis</I> <B>100</B>, 2352–2363). We assess the reasonableness of the KP structure with a score test. A maximum marginal likelihood estimation method is proposed utilizing a quasi-Newton algorithm with quasi-Monte Carlo integration of the random effects. We examine the effects of demographic factors on metabolic syndrome and C-reactive protein using the proposed models.</P>

In Situ Forming Gelatin Hydrogels-Directed Angiogenic Differentiation and Activity of Patient-Derived Human Mesenchymal Stem Cells

Lee, Yunki,Balikov, Daniel A.,Lee, Jung Bok,Lee, Sue Hyun,Lee, Seung Hwan,Lee, Jong Hun,Park, Ki Dong,Sung, Hak-Joon MDPI 2017 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.18 No.8

<P>Directing angiogenic differentiation of mesenchymal stem cells (MSCs) still remains challenging for successful tissue engineering. Without blood vessel formation, stem cell-based approaches are unable to fully regenerate damaged tissues due to limited support for cell viability and desired tissue/organ functionality. Herein, we report in situ cross-linkable gelatin−hydroxyphenyl propionic acid (GH) hydrogels that can induce pro-angiogenic profiles of MSCs via purely material-driven effects. This hydrogel directed endothelial differentiation of mouse and human patient-derived MSCs through integrin-mediated interactions at the cell-material interface, thereby promoting perfusable blood vessel formation in vitro and in vivo. The causative roles of specific integrin types (α<SUB>1</SUB> and α<SUB>v</SUB>β<SUB>3</SUB>) in directing endothelial differentiation were verified by blocking the integrin functions with chemical inhibitors. In addition, to verify the material-driven effect is not species-specific, we confirmed in vitro endothelial differentiation and in vivo blood vessel formation of patient-derived human MSCs by this hydrogel. These findings provide new insight into how purely material-driven effects can direct endothelial differentiation of MSCs, thereby promoting vascularization of scaffolds towards tissue engineering and regenerative medicine applications in humans.</P>

Intermediate-term outcomes after robotic ureteral reconstruction for long-segment (≥4 centimeters) strictures in the proximal ureter: A multi-institutional experience

Matthew Lee,Ziho Lee,Helaine Koster,Minsuk Jun,Aeen M. Asghar,Randall Lee,David Strauss,Neel Patel,Daniel Kim,Sreeya Komaravolu,Alice Drain,Michael J. Metro,Lee Zhao,Michael Stifelman,Daniel D. Eun 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.1

Purpose: To report our intermediate-term, multi-institutional experience after robotic ureteral reconstruction for the management of long-segment proximal ureteral strictures. Materials and Methods: We retrospectively reviewed our Collaborative of Reconstructive Robotic Ureteral Surgery (CORRUS) database to identify all patients who underwent robotic ureteral reconstruction for long-segment (≥4 centimeters) proximal ureteral strictures between August 2012 and June 2019. The primary surgeon determined the specific technique to reconstruct the ureter at time of surgery based on the patient's clinical history and intraoperative findings. Our primary outcome was surgical success, which we defined as the absence of ureteral obstruction on radiographic imaging and absence of obstructive flank pain. Results: Of 20 total patients, 4 (20.0%) underwent robotic ureteroureterostomy (RUU) with downward nephropexy (DN), 2 (10.0%) underwent robotic ureterocalycostomy (RUC) with DN, and 14 (70.0%) underwent robotic ureteroplasty with buccal mucosa graft (RU-BMG). Median stricture length was 4 centimeters (interquartile range [IQR], 4–4; maximum, 5), 6 centimeters (IQR, 5–7; maximum, 8), and 5 centimeters (IQR, 4–5; maximum, 8) for patients undergoing RUU with DN, RUC with DN, and RU-BMG, respectively. At a median follow-up of 24 (IQR, 14–51) months, 17/20 (85.0%) cases were surgically successful. Two of four patients (50.0%) who underwent RUU with DN developed stricture recurrences within 3 months. Conclusions: Long-segment proximal ureteral strictures may be safely and effectively managed with RUC with DN and RU-BMG. Although RUU with DN can be utilized, this technique may be associated with a higher failure rate.

Auto-guiding Performance from IGRINS Test Observations (Immersion GRating INfrared Spectrograph)

Hye-In Lee,Soojong Pak,Huynh Anh N.Le,Wonseok Kang,Gregory Mace,Michael Pavel,Daniel T.Jaffe,Jae-Joon Lee,Ueejeong Jeong,Michael Pavel,Daniel T.Jaffe,Jae-Joon Lee,Ueejeong Jeong,Moo-Young Chun,Chan Pa 한국천문학회 2014 天文學會報 Vol.39 No.2

Severe Adverse Events of Periocular Acupuncture: A Review of Cases

Sang-Mok Lee(Sang-Mok Lee),Jun Wu(Jun Wu),Daniel Duck-Jin Hwang(Daniel Duck-Jin Hwang ) 대한안과학회 2023 Korean Journal of Ophthalmology Vol.37 No.3

Acupuncture is recognized as a component of alternative medicine and is increasingly used worldwide. Many studies have shown the various effects of acupuncture around the eyes for ophthalmologic or nonophthalmologic conditions. For ophthalmologic conditions, the effect of acupuncture on dry eye syndrome, glaucoma, myopia, amblyopia, ophthalmoplegia, allergic rhinoconjunctivitis, blepharospasm, and blepharoptosis has been reported. Recently, several studies on dry eye syndrome have been reported and are in the spotlight. However, given the variety of study designs and reported outcomes of periocular acupuncture, research is still inconclusive, and further studies are required. In addition, although a systematic and reliable safety assessment is required, to the best of our knowledge, there have been no reports of a literature review of ocular complications resulting from periocular acupuncture. This review collected cases of ocular injury as severe adverse events from previously published case reports of periocular acupuncture. A total of 14 case reports (15 eyes of 14 patients) of adverse events published between 1982 and 2020 were identified. This review article provides a summary of the reported cases and suggestions for the prevention and management of better visual function prognosis.

Christianity Encounters Confucianism : Spiritual Formation in a Comparative Perspective in Korea

Lee, Daniel Chungsoon 한국실천신학회 2017 신학과 실천 Vol.0 No.55

A religious pluralism is not a strange phenomenon in Korea because the Korean society consists of various living religions. Christianity is just one of those religions. Although Korean Christianity’s history, Catholic and Protestant, is not long, it has occupied a quarter of the whole population in south Korea. So, Christianity, a foreign Western religion, now exists as one of the main religions in Korea. Although Christianity is now a Korean people’s religion, it is also true that the Christianity introduced from Western countries is still not indigenized or inculturized into Korean culture in a true sense. That is, Christianity in Korea does not fully understand Korea’s pluralistic religious culture, so it still regards it as heretical. In this context, achieving a true encounter between Christian faith and Korean religious cultures is an important task for Christianity in Korea. It is extremely significant for Korean Christians to study comparatively other religions as living partners for Christian faith in order to make Christianity spiritually rich and fruitful in the Korean context. Although the main streams of Christianity are conservative and still opposed to other traditional religions, it is evident that Christianity in Korea has been influenced by other traditional religious cultures in whatever. In particular, the Confucian influence on Christianity in Korea was so strong because the state religion of the Choson dynasty, which lasted until the Japanese occupation in the modern times of Korea, was Confucianism. Even though many people don’t confess Confucianism as their religion, it is undeniable that Confucianism is functioning as a core and basis of Korean lives and cultures. The purpose of this paper is to explore spiritual formation for Korean Christians by doing a comparative study of Christianity and Confucianism in Korea. In this paper, I have dealt with the important issue, “Confucian-Christian dialogue” in the Korean context, focusing on the theme of spirituality. I first tried to define the term ‘spirituality’ from a comparative perspective. Second, with reference to the experience of interfaith encounters in Korea, I have searched for some models of Christian spirituality and spiritual formation which are desirable in the context of Korea. As conclusion, I have discussed about several tasks for the encounter between Christianity and Confucianism, especially for a spiritual formation in the context of the Korean Churches.

Several Regions in the Major Histocompatibility Complex Confer Risk for Anti-CCP-Antibody Positive Rheumatoid Arthritis, Independent of the DRB1 Locus

Lee, Hye-Soon,Lee, Annette T.,Criswell, Lindsey A.,Seldin, Michael F.,Amos, Christopher I.,Carulli, John P.,Navarrete, Cristina,Remmers, Elaine F.,Kastner, Daniel L.,Plenge, Robert M.,Li, Wentian,Greg Springer (Biomed Central Ltd.) 2008 Molecular Medicine Vol.14 No.5

<P>Recent evidence suggests that additional risk loci for RA are present in the major histocompatibility complex (MHC), independent of the class II HLA-DRB1 locus. We have now tested a total of 1,769 SNPs across 7.5Mb of the MHC located from 6p22.2 (26.03 Mb) to 6p21.32 (33.59 Mb) derived from the Illumina 550K Beadchip (Illumina, San Diego, CA, USA). For an initial analysis in the whole dataset (869 RA CCP + cases, 1,193 controls), the strongest association signal was observed in markers near the HLA-DRB1 locus, with additional evidence for association extending out into the Class I HLA region. To avoid confounding that may arise due to linkage disequilibrium with DRB1 alleles, we analyzed a subset of the data by matching cases and controls by DRB1 genotype (both alleles matched 1:1), yielding a set of 372 cases with 372 controls. This analysis revealed the presence of at least two regions of association with RA in the Class I region, independent of DRB1 genotype. SNP alleles found on the conserved A1-B8-DR3 (8.1) haplotype show the strongest evidence of positive association (P ~ 0.00005) clustered in the region around the HLA-C locus. In addition, we identified risk alleles that are not present on the 8.1 haplotype, with maximal association signals (P ~ 0.001-0.0027) located near the ZNF311 locus. This latter association is enriched in DRB1*0404 individuals. Finally, several additional association signals were found in the extreme centromeric portion of the MHC, in regions containing the DOB1, TAP2, DPB1, and COL11A2 genes. These data emphasize that further analysis of the MHC is likely to reveal genetic risk factors for rheumatoid arthritis that are independent of the DRB1 shared epitope alleles.</P>

Gains Achieved by Symbol-by-Symbol Rate Adaptation on Error-Constrained Data Throughput over Fading Channels

Lee, Daniel C.,Tsaur, Lih-Feng The Korea Institute of Information and Commucation 2007 Journal of communications and networks Vol.9 No.3

Methods for symbol-by-symbol channel feedback and adaptation of symbol durations have been recently proposed. In this paper, we quantitatively analyze the gain in error-constrained data throughput due to such an extremely rapid adaptation of symbol durations to fast-time-varying channels. The results show that a symbol-by-symbol adaptation can achieve a throughput gain by orders of magnitude over a frame-by-frame adaptation.

Encountering God in Prayer and Action - A Theological Analysis of Simone Weil’s Spiritual Autobiography -

Lee, Daniel Chungsoon 한국실천신학회 2016 신학과 실천 Vol.0 No.50

Simone Weil (1909-1943), whose life is marked by hunger, suffering, and social praxis in a tumultuous time, is regarded as a great modern mystic in history of Christian spirituality. Although she did not want to belong to any institutionalize church, she was a mystic, experiencing God in an immediately way. She was striving for God, actively engaged in social, political issues in her time. In the mid-1930s Weil became increasingly drawn to Christianity but refused baptism into the Christian Church. However, she finally converted from Judaism to Christianity in 19131. As her faith dawned, Weil had strongly mystic experiences several times. She stayed outside of any church, but her passionate need to share the sufferings of others led her to fight with the anarchists in the Spanish Civil War and to work as a laborer. She ultimately died in England at the age of 34 by refusing to eat more than the rations Hitler allotted to her countrymen in occupied France. The extraordinary life of Simone Weil gave us a strong impression of a saint because she practiced the suffering way of Jesus Christ in her own life. Above of all, she shows us a way of encountering God in both her internal life and the suffering world, a spirituality balanced between personal prayer, contemplation, and social praxis. In addition, her spiritual journey teaches us the meaning of faith, prayer, mysticism, ritual, and church. Thus, it seems obvious that her spirituality can help us reflect ourself as Christians and formulate a spirituality of genuine prayer and action in the context of Korean churches. In this regard, it is timely significant to theologically analyze her spiritual autobiography to gain an understanding of spirituality from a new perspective in this changing world. In this article, I will explore her spirituality, focusing on her spiritual and theological writings collected in Waiting for God. In particular, I will fucus on her spiritual journey, centering on several turning points. I will first explicate the significance of her spiritual autobiography as a form of autobiography. Then, I will discuss her thought on theological themes such as God, Christ, mystical experience, truth, beauty, suffering, and Christianity. Last, I will critique some of her thought in order to develop a balanced spirituality between self and others, personal contemplation and social praxis in the context of the Korean church.