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Dai Jian-Qing,Yuan Jin 한국물리학회 2021 Current Applied Physics Vol.29 No.-
In this work, we report on the structural, electronic, and ferroelectric properties of SmMn2O5 by using firstprinciples density functional theory plus on-site Coulomb interaction (DFT + U) calculations. A thorough analysis was preformed to reveal the competing characteristics of different high-temperature (T) phases and the polarization mechanism in the low-T multiferroic phase. We show that the structural characteristics of the high-T phases have a strong influence on the low-T multiferroicity. In addition to the spin-induced lattice distortion that reduces substantially the purely electronic ferroelectricity, the dominant polarization mechanism in low-T SmMn2O5 still originates from the electronic polarization. By performing mode decomposition of the Hellmann– Feynman forces and the lattice distortion induced by the q = (0.5, 0, 0) magnetic order, we find that the Raman-active Ag mode characterized by the Mn4+O6 octahedron distortion and synergistic displacement of Mn3+ and Sm ions is of primary importance, while the infrared (IR)-active B2u mode plays a secondary role. These findings provide a theoretical foundation for future studies concerning the enhanced magnetoelectric effects of SmMn2O5 due to its pure exchange–striction mechanism.
Song, Chuan-Qing,Zhang, Jun-Hui,Shi, Jia-Chen,Cao, Xiao-Qin,Song, Chun-Hua,Hassan, Adil,Wang, Peng,Dai, Li-Ping,Zhang, Jian-Ying,Wang, Kai-Juan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
Polymorphisms in miRNA binding sites have been shown to affect miRNA binding to target genes, resulting in differential mRNA and protein expression and susceptibility to common diseases. Our purpose was to predict SNPs (single nucleotide polymorphisms) within miRNA binding sites of inflammatory genes in relation to gastric cancer. A complete list of SNPs in the 3'UTR regions of all inflammatory genes associated with gastric cancer was obtained from Pubmed. miRNA target prediction databases (MirSNP, Targetscan Human 6.2, PolymiRTS 3.0, miRNASNP 2.0, and Patrocles) were used to predict miRNA target sites. There were 99 SNPs with MAF>0.05 within the miRNA binding sites of 41 genes among 72 inflammation-related genes associated with gastric cancer. NF-${\kappa}B$ and JAK-STAT are the two most important signaling pathways. 47 SNPs of 25 genes with 95 miRNAs were predicted. CCL2 and IL1F5 were found to be the shared target genes of hsa-miRNA-624-3p. Bioinformatic methods could identify a set of SNPs within miRNA binding sites of inflammatory genes, and provide data and direction for subsequent functional verification research.
Comparative study of a typical model between beijing courtyard and fujian Earth Building
Gong Wei qing,Dai Jian 국제온돌학회 2009 International Journal of Ondol Vol.2009 No.-
In this paper, the Beijing courtyard and Fujian Earth Building--model for two typical entry points, through both a comparative analysis of the typical form and from the perspective of traditional Chinese culture to explain the differences between the two shapes in order to explore the south and the north of China s residential cultural similarities and differences.
Li-Shang Dai,Cen Qian, LeiWang,Guo-Qing Wei,Qiu-Ning Liu,Yu Sun,Cong-Fen Zhang,Jun Li,Dong-Ran Liu,Bao-Jian Zhu,Chao-Liang Liu 한국응용곤충학회 2015 Journal of Asia-Pacific Entomology Vol.18 No.4
Peptidoglycan recognition proteins (PGRPs) are conserved proteins in animals from insects to mammals and play an important role in immune response by recognizing peptidoglycan on microbial surfaces. In this study, a PGRP gene from Antheraea pernyi, named Ap-PGRP-A, was isolated and characterized. Sequence analysis revealed that the full-length cDNA of Ap-PGRP-A was 961 bp, containing a 40 bp 5′-untranslated sequence, a 339 bp 3′-untranslated region and an open reading frame of 582 bp. This gene encoded a putative protein of 193 amino acid residues. Phylogenetic analysis indicated that Ap-PGRP-A had the closest protein sequence similarity to Antheraea mylitta PGRP. The recombinant protein was successfully expressed in Escherichia coli cells and a rabbit anti-Ap-PGRP-A antibody was also prepared. Real-time quantitative reverse transcription-PCR analysis showed that Ap-PGRP-A was extensively expressed in the fat body, midgut, hemocyte,malpighian tubule and epidermis of A. pernyi, especially in the fat body and midgut. The expression levels of Ap-PGRP-A were significantly up-regulated by three types of microorganisms, and Ap-PGRP-A expression was more sensitive in response to the Gram-negative bacterium E. coli than the Gram-positive bacterium Bacillus subtilis or the fungus Beauveria bassiana. These data indicate that Ap-PGRP-A may play a role in the innate immune responses of A. pernyi.
A Novel Hysteresis Control Strategy Based on Ampere-Second Balance of the Modulate Capacitor
Zhao, Jin-Bin,Dai, Jian-Feng,Qu, Ke-Qing,Li, Fen The Korean Institute of Power Electronics 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.6
A novel hysteresis PWM control strategy for synchronous buck converter is proposed. The proposed control strategy is based on ampere-second balance of the modulate capacitor, which not only offers faster transient response to meet the challenges of the power supply requirements of fast dynamic load changes, but also provides better stability and solves the compensation problem of error amplifier in the conversional voltage PWM control. Finally, the steady-state and dynamic operation of the control method is analyzed and verified by simulation and experimental results.
Two New Phenolic Compounds from the Fruiting Bodies of Ganoderma tropicum
Hu, Li-Li,Ma, Qing-Yun,Huang, Sheng-Zhuo,Guo, Zhi-Kai,Guo, Jian-Chun,Dai, Hao-Fu,Zhao, You-Xing Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.3
Chemical investigation of the fruiting bodies of Ganoderma tropicum led to the isolation of two new phenolic compounds, ganodermatropins A (1) and B (2). Their structures were elucidated by spectroscopic techniques (MS, 1D and 2D NMR). Ganodermatropin A exhibited antimicrobial activity against Staphylococcus aureus.
Yu-Min Song,Jian-Qing Dai,Hu Zhang 한국물리학회 2016 Current Applied Physics Vol.16 No.1
We present the electronic, dielectric, and optical properties of layered perovskite pure and N-doped Sr2M2O7 (M ¼ Nb and Ta) based on density functional theory with the HSE06 approximation. The band gaps for pure Sr2M2O7 (M ¼ Nb and Ta) are consistent with the experimental data. Optical properties are obtained and compared with the experimental results. Pure Sr2Nb2O7 and Sr2Ta2O7 have broad applications in photocatalysis in the ultra-violet region. In contrast with Sr2Ta2O7, the absorption ability of Sr2Nb2O7 is slightly stronger. The N doping in Sr2Nb2O7 shifts the light absorption boundary into the visible region. The optical absorption effect of Sr2Nb2O5N2 is better than Sr2Nb2O6.5N0.5 in the visible region. The N doping in Sr2Ta2O7 reduces the band gap and produces visible light absorptions. Sr2Ta2O5N2 shows higher absorption effect in the visible light region than Sr2Ta2O6.5N0.5.
A Novel Hysteresis Control Strategy Based on Ampere-Second Balance of the Modulate Capacitor
Jin-Bin Zhao,Jian-Feng Dai,Ke-Qing Qu,Fen Li 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.6
A novel hysteresis PWM control strategy for synchronous buck converter is proposed. The proposed control strategy is based on ampere-second balance of the modulate capacitor, which not only offers faster transient response to meet the challenges of the power supply requirements of fast dynamic load changes, but also provides better stability and solves the compensation problem of error amplifier in the conversional voltage PWM control. Finally, the steady-state and dynamic operation of the control method is analyzed and verified by simulation and experimental results.
Zhang, Guo Hua,Lu, Jian Xiong,Chen, Yan,Dai, Hong Wei,ZhaXi, YingPai,Zhao, Yong Qing,Qiao, Zi Lin,Feng, Ruo Fei,Wang, Ya Ling,Ma, Zhong Ren Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.11
Lipogenesis is under the concerted action of ChREBP, SREBP-1c and other transcription factors in response to glucose and insulin. The isolated porcine preadipocytes were differentiated into mature adipocytes to investigate the roles and interrelation of these transcription factors in the context of glucose- and insulin-induced lipogenesis in pigs. In ChREBP-silenced adipocytes, glucose-induced lipogenesis decreased by ~70%, however insulin-induced lipogenesis was unaffected. Moreover, insulin had no effect on ChREBP expression of unperturbed adipocytes irrespective of glucose concentration, suggesting ChREBP mediate glucose-induced lipogenesis. Insulin stimulated SREBP-1c expression and when SREBP-1c activation was blocked, and the insulin-induced lipogenesis decreased by ~55%, suggesting SREBP-1c is a key transcription factor mediating insulin-induced lipogenesis. $LXR{\alpha}$ activation promoted lipogenesis and lipogenic genes expression. In ChREBP-silenced or SREBP-1c activation blocked adipocytes, $LXR{\alpha}$ activation facilitated lipogenesis and SREBP-1c expression, but had no effect on ChREBP expression. Therefore, $LXR{\alpha}$ might mediate lipogenesis via SREBP-1c rather than ChREBP. When ChREBP expression was silenced and SREBP-1c activation blocked simultaneously, glucose and insulin were still able to stimulated lipogenesis and lipogenic genes expression, and $LXR{\alpha}$ activation enhanced these effects, suggesting $LXR{\alpha}$ mediated directly glucose- and insulin-induced lipogenesis. In summary, glucose and insulin stimulated lipogenesis through both dissimilar and identical regulation pathway in porcine adipocytes.
Lin Shuang-Zhe,Wu Wei-Jie,Cheng Yu-Qing,Zhang Jian-Bin,Jiang Dai-Xi,Ren Tian-Yi,Ding Wen-Jin,Liu Mingxi,Chen Yuan-Wen,Fan Jian-Gao 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Macrophages are immune cells crucial for host defense and homeostasis maintenance, and their dysregulation is involved in multiple pathological conditions, such as liver fibrosis. The transcriptional regulation in macrophage is indispensable for fine-tuning of macrophage functions, but the details have not been fully elucidated. Prolyl endopeptidase (PREP) is a dipeptidyl peptidase with both proteolytic and non-proteolytic functions. In this study, we found that Prep knockout significantly contributed to transcriptomic alterations in quiescent and M1/M2-polarized bone marrow-derived macrophages (BMDMs), as well as aggravated fibrosis in an experimental nonalcoholic steatohepatitis (NASH) model. Mechanistically, PREP predominantly localized to the macrophage nuclei and functioned as a transcriptional coregulator. Using CUT&Tag and co-immunoprecipitation, we found that PREP was mainly distributed in active cis-regulatory genomic regions and physically interacted with the transcription factor PU.1. Among PREP-regulated downstream genes, genes encoding profibrotic cathepsin B and D were overexpressed in BMDMs and fibrotic liver tissue. Our results indicate that PREP in macrophages functions as a transcriptional coregulator that finely tunes macrophage functions, and plays a protective role against liver fibrosis pathogenesis.