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Chung, Hyung-Koo,Lee, Won-Kyu,Park, Hong-Gyu,Lee, Hak Moo,Jeong, Hae-Chang,Cho, Min-Cha,Seo, Dae-Shik Optical Society of America 2014 Optics express Vol.22 No.18
<P>Uniaxial alignment of liquid crystals (LCs) is prerequisite for a vast number of LC applications. To accomplish stable and uniform LC orientation, an alignment process to orient the LCs is required. Herein, we demonstrate a simple strategy for fabricating novel LC alignment layers that ensures well aligned LC, superior switching without any capacitance hysteresis, low transmittance loss, and high thermal stability with sufficient anchoring action. Thin films of reactive mesogens (RMs) were transferred onto conventional homeotropic polyimides from a UV-cured RM stamp via contact printing. LC displays using defect free RM/PI polymeric stacks exhibited superior electro-optic (EO) properties to those containing rubbed PI layers. This approach allows for the fabrication of various-mode LC displays such as twisted nematic (TN), in-plane switching (IPS), and optically compensated bend (OCB) mode LCDs by changing the combinations of RMs, base PIs and LCs.</P>
Effect of 2,3,3',4,4'-Pentachlorobiphenyl (PCB#105) on Rat Testes
Chung-Kil Won,Oh-Sung Park,Dae-yong Han,Phil-Ok Koh,Jae-Hyeon Cho,Eun-Hee Kim,Gon-Sup kim 한국실험동물학회 2007 Laboratory Animal Research Vol.23 No.3
This study was conducted to examine the effect of 2,3,3',4,4'-pentachlorobiphenyl (PCB#105) on the reproductive function of male rats. PCB#105 (0.01, 0.1, 0.5 ㎍/㎏/day) in corn oil was orally administrated to adult male rats for 10 weeks. The body and testicular weights, and the serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), were measured at 2, 4, 6, 8 and 10 weeks of PCB treatment. The morphological changes in the rat testes were than analyzed by light microscopy (LM) and transmission electron microscopy (TEM). The results showed that PCBs caused no significant change in the body weights but caused a marked decrease in their testicular weights. A decrease in the serum LH and FSH levels of the PCB-treated rats was also observed. Moreover, the morphological studies that were conducted on the PCB-treated rats revealed that the size of their seminiferous tubules slightly decreased (LM), and that their nuclear membrane was damaged when 0.1 ㎍/㎏/day PCB was administered to them for 10 weeks (TEM). These results suggest that the reproductive function of the adult male rats is sensitive to PCB, and that may affect their LH and FSH secretion.
Assessing Cure Rates via Piecewise Gompertz model with Covariates
Chung, Dae-Hyun,Won, Dong-Yu The Korean Data and Information Science Society 1999 한국데이터정보과학회지 Vol.10 No.2
We modify the Gompertz regression model for estimation of cure rates from pediatric clinical trials by assuming different hazard rates on the different periods. A treatment period may be divided by the stages of treatments under the different treatment arms. The piecewise Gompertz models provide an efficient method for estimation of the cure rates and a method for testing the difference of the treatment effects in the given interval.
구연 : 버드-키아리 증후군에 동반된 간세포암의 특징적 임상상: B형 간염 관련 간세포암과의 비교
( Won Beom Choi ),( Young Hwa Chung ),( Sang Hyo Shin ),( Dong Dae Suh ),( Sung Hoon Kim ),( Myoung Kuk Jang ),( In Sook Kim ),( Jung Woo Shin ),( Soo Hyung Ryu ),( Neung Hwa Park ),( Han Chu Lee ),( 대한간학회 2003 Clinical and Molecular Hepatology(대한간학회지) Vol.9 No.3(S)
Background/Aims: Budd-Chiari syndrome (BCS) has been known as a risk factor of hepatocellular carcinoma (HCC). Considering the pathophysiologic mechanism of BCS, HCC associated with BCS may have a different carcinogenic process resulting in characteristic