Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants

Che´rif Rabhi,Guillaume Arcile,Le´on Cariel,Christine Lenoir,Je´rome Bignon,Joanna Wdzieczak-Bakala,Jamal Ouazzani 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9

The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex® technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.

제주 우수 수영 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe the annual effect of training of periodically anaerobic and erobic motor ability for Che-Ju representive team of elementary, middle and high school athletes, first the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events, second individually fitness scientific analysis. prescription. proper management of athlete will be necessary to apply.

제주 우수 육상경기 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe t h e annual effect of training of periodically anaerobic and aerobic motor ability for Che-Ju representive team of elementary, middle and high school athletes. first. the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events. second, individually fitness. scientific analysis. prescription. proper management of athlete will be necessary to apply. In addition to physiology aspect, it is essential to consider sport biomechanics. sport psychology when we prescribe specific events and necessary approach in demension coach-athlete-researcher for individual.

의료소비자의 관계혜태 지각이 관계의 질 및 행동의도에 미치는 영향

허철선(Che이-Seon Heo),유광우(Kwang-Woo Yoo) 한국무역연구원 2014 무역연구 Vol.10 No.1

Medical institutions are important to develop and maintain enduring relationship with medical service conswners. So, this research aims to find out the effect of medical service conswners perception of relational benefits on relationship quality and behavioral intention. On the basis of the literature review, the research model is established. This research has been done through the survey utilizing medical service consumers in Gangwondo, and the effective 368 questionnaires are tested for the research model. The main findings are as follows. First, among 5 key dimensions of relational benefits, psychological, customization, economic, and information benefits except social benefits have significant effects on relationship satisfaction. Also, medical institutions type and medical service consumers type as moderating variables are included concurrently, and the significant differences are found in other 4 benefits except relationship between social benefits and relationship satisfaction. Second, relationship satisfaction relates positively to relationship commitment and behavioral intention. But the normative commitment, one of 3 key dimensions of relationship commitment, has no significant effects on recommendation to others. Third, the revisit intention has significant effect on recommendation to others. Finally, the findings reveal that the overall goodness fit index of the model is comparatively good and model set in this research is significant. At the end of the research, managerial implications, limitations and future research directions are suggested.

의료 화상을 위한 전처리 필터들의 특성에 관한 연구

강명아,최종주,정종필,정채영,정남채 조선대학교 기초과학연구소 1997 自然科學硏究 Vol.20 No.1

There has been no fixed rule of pre-processing course required to do image processing that it was barely possible to find the proper pre-processing course, only to process with experience till now. In this paper, lots of application method of pre-processing algorithm, only available by the non-typified and experiential method, shall quantify and the algorithm method of algorithm according to the rule shall calculate the frequency of the value of each pixel gray level and the histogrm of the image. And then average it to all pixel number and finally set a high-ranking or optional % standardized by the average value in teh standard value. The result of a experiment showed the Median filter is superior to the Mean filter in all image of the smoothing filter. The sobel filter extracted feature. The laplacian filter presented sectional feature which not showed in original image.

숙련자와 미숙련자의 배드민턴 스매시 동작의 운동학적 비교 분석

류재청,김익상 한국운동역학회 2003 한국운동역학회지 Vol.13 No.2

Ryew, C-C and Kim, I-S. Kinematic Analysis of Badminton Smashing Between the Skilled and the Unskilled. Korean Journal of Sport Biomechanics, Vol. 13, No. 2, pp. 139-160. The purpose of this study was to suggest the guideline for scientific and quantitative skill acquisition methods of badminton smashing so that the novice could learn the motions of badminton smashing efficiently. The subject participated consisted of total 6 middle school students of the skilled(3) and the unskilled(3). The cinematographical experimental & Analysis equipments used in the study were composed of two Model D-5100 Video Cameras, a control point, a synchronization timer and Kwon3d motion analysis system. The conclusions obtained were as follows; 1. It was necessary for the unskilled to learn the smashing impact phase in situation of max. Velocity of COG in order to minimize the timing loss phase. 2. Particularly, The power from segments of Power Zone must participate in utilization in sequence of order of trunk-upper arm-forearm-hand-racket segment in both the skilled and the unskilled. 3. Therefore It was necessary for the unskilled to do smashing practice for cumulated sum of absolute & relative velocity transfer into shuttle cock after adjusting anterior-posterior tilting angle and max timing, in sequence of segment recruited.

두 가지 고장 형태를 가진 제품의 비용모형

김제숭 尙志大學校 生産技術硏究所 2000 生産技術論叢 Vol.8 No.-

This paper is concerned with warranty cost models for a product with two types of failure: type1 failures corrected by minimal repair and type2 failures removed only by replacement. Two warranty policies involving an initial free service period followed by a pro-rata period are considered; the difference is whether the warranty is renewed or not when type2 failure occurs during its free service period. Expected warranty costs under the two policies are obtained, and their behaviors are examined for the case where type 1 and 2 failure distributions are Weibull and exponential, respectively.

Micro-sociology의 건축적 적용에 관한 연구

林采震 홍익대학교 산업기술연구소 1994 産業技術 Vol.4 No.-

Based on the theory of sociometry, which initiated by Moreno, this study explore the possibility of expanding the theory into utilization in architectural planning. Because the main concern of the study is human behaviors in the institution setting. the patient area of a hospital has been chosen. After observations of the patient area (i.e single two-persons fur- six- and larger ward) some of the findings are as follows. 1) Social interactions are most frequent within the ward 2) Inter -ward interactions are influcened by distance and 3) Gender and social background in the group significantly interfere the interactions. The study, therefore, concludes that the size of ward and the characteristics of group significantly affects the human behaviors.

Heinrich Heine의 Realismus에 關한 考察

韓在弘 釜山大學校 師範大學 1975 교사교육연구 Vol.2 No.1

Bei Heine erscheint das Zeigen des Auswegs gegen den Feudalismus konkret; es ist, wie die Volksbewegung den Menschen weckt, sein Geistleben aufbluhen laBt, ihm kraft und Liebe verleiht. Bei keinem seiner Zeitgenossen ist die Emporung gegen das Alte so mitreiBend, das Pathos des Neuen so begeisternd wie bei Heine. In dieser Frage der Verteidigung zertretener Menschenwiirde, der Verteidignng des verhinderten Menschseins ist Heinrich Heine radikaler und entschlossener als Wolfgang von Goethe. Auch diese konnen bei Heine eine groBe Rolle spielen; entscheidend ist die objektive Fortsetzung der groBten humanistischen Probleme der bisherigen Menschheitsentwicklung. Heine sucht nun die HarmOnie des Menschen und die ihr entsprechende Schonheit in der Kunst. Sdnst wirken die groBen Dichter, wie Goethe, der klassisehen Periode Deuts- chlands bereits nach der Franzosischen Revolution und haben deshalb die heroischen Illusion der Aufkl'arung verloren. Heine bietet dem Menschen eine starke Waffe im Kampf gegen das primitive Privileg- iensystem des Feudalismus und scharfe Waffen fur den Kampf gegen den Feudalismus und die absolute Monarchie an. Mit sturmischem Enthusiasmus und seiner genialen Fahigkeiten arbeitet Heine fiir die Befreiung aus Feudalismus; das heiBt: ich versuchte es, wie in Frankreich Julirevolution und in Deutschland Hambachfest Heinrich Heine verzieren.

스쿠버 활동시 감압증 이론과 관련한 제요인의 원인과 예방법에 관한 고찰

류재청 濟州大學敎 體育科學硏究所 1997 체육과학연구 Vol.3 No.-

This review was undertaken to search the way for safe diving concerned with decompression sickness and types. Nitrogen saturation diving. Recompression equipments and theories of decompresiion sickness 1. The orgin og decompression theory Recent all theories of decompression sickness was originated from 「Caisson or Bends」 mean and based on Haldene thoery(1908). Theory shifted rom Haldene theory after that were theory of saturation diving. Haldane-Royal Navy table. U.S. Navy Diving Table(1965). Royal Navy Theory. Swiss theory, Canada theory, Dive Science and Technology Corporation(DSAT. 1987) 2. Women and decompression Woman were more suspectible to deccompression sickness than men because of first. having more body fat tissue. second more supectible decompression due to stream of body fluid during mensturation. third unbalanced circulation due to birth control pill. The symptoms generating in diving of pregnanent women consist of squeeze, air embolism. Decompression sickness but these did not any problem on fetus. 3. Equipments for prevention of decompression sickness 1) Dive tables Many decompression tables developed on the basis of on U.S. Navy Diving Table used Haldene theory were NAUI. PEDI. BASAC etc. and the content composed in common was to avoid decompression sicness in safety stop(3min stop at 15 feet). The skill to be practice on dive tables conist of resign of repetitive diving letter. Adjusted Maximum Dive Time(AMDT). min. surface interval time). Allowable max. depth in repetitive diving. RNT. SIT etc. 2) Gagues The most popular gauage using to avoid decompression sickness were capillary type depth gauge. diaphragm type depth gauge, oil-filled type depth gauge, analog digital type, analog digital submersible type. dive computer. Particularly It is recommanded to use dive computer display accurate absorption of Nitrogen, depth to avoid penalty of 「maximum-time at maximum-depth」 in multi-level diving. 3) Decompression prevention It is said to redecompression to treat serious symptom of decompression & air embolism. operated in recompression chambers. If you omitted safety stop. It is necessory to position of shock prevention, must be rest providing with pure 100% oxygen certifing symptom of decompression sickness, and be carried to hyperbaric facility. The height of flying after dive must not be superceded 8000 feet, at least before 24 hours. It is desirable to dive shorter and deeper than shallower and longer diving when scheduled of flight.