Convergence of a linearly transformed particle method for aggregation equations

Campos Pinto, Martin,Carrillo, José,A.,Charles, Fré,dé,rique,Choi, Young-Pil Springer Berlin Heidelberg 2018 Numerische Mathematik Vol.139 No.4

<P>We study a linearly transformed particle method for the aggregation equation with smooth or singular interaction forces. For the smooth interaction forces, we provide convergence estimates in [FORMULA OMISSION] and [FORMULA OMISSION] norms depending on the regularity of the initial data. Moreover, we give convergence estimates in bounded Lipschitz distance for measure valued solutions. For singular interaction forces, we establish the convergence of the error between the approximated and exact flows up to the existence time of the solutions in [FORMULA OMISSION] norm.</P>

Application of Bonelike® as synthetic bone graft in orthopaedic and oral surgery in veterinary clinical cases.

José Miguel Campos,Ana Catarina Sousa,Pedro Olivério Pinto,Jorge Ribeiro,Miguel Lacueva França,Ana Rita Caseiro,Mariana Vieira Branquinho,Sílvia Santos Pedrosa,Carla Mendonça,Ana Brandão,José Domingos 한국생체재료학회 2019 생체재료학회지 Vol.23 No.1

Autologous bone remains the gold standard grafting substrate for bone fusions used for small gaps and critical defects. However, significant morbidity is associated with the harvesting of autologous bone grafts and, for that reason, alternative bone graft substitutes have been developed. In the present case series, a glass-reinforced hydroxyapatite synthetic bone substitute, with osteoinductive and osteoconductive proprieties, was applied. This synthetic bone substitute comprises the incorporation of P2O5-CaO glass-based system within a hydroxyapatite matrix, moulded into spherical pellets with 250-500 μm of diameter. A total of 14 veterinary clinical cases of appendicular bone defects and maxillary / mandibular bone defects are described. In all clinical cases, the synthetic bone substitute was used to fill bone defects, enhancing bone regeneration and complementing the recommended surgical techniques. Results demonstrated that it is an appropriate synthetic bone graft available to be used in veterinary patients. It functioned as a space filler in association with standard orthopaedic and odontological procedures of stabilization, promoting a faster bone fusion without any local or systemic adverse reactions. This procedure improves the animals’ quality of life, decreasing pain and post-operative recovery period, as well as increasing bone stability improving positive clinical outcomes.

Ultrasound biomicroscopy for the assessment of early-stage nonalcoholic fatty liver disease induced in rats by a high-fat diet

Antonio Carlos Soares Pantaleão,Marcio Pinto de Castro,Krishynan Shanty Fernandes Meirelles Araujo,Carlos Frederico Ferreira Campos,André Luiz Alves da Silva,José Eduardo Ferreira Manso,João Carlos Ma 대한초음파의학회 2022 ULTRASONOGRAPHY Vol.41 No.4

Purpose: The aim of this study was to assess the ability of ultrasound biomicroscopy (UBM) to diagnose the initial stages of nonalcoholic fatty liver disease (NAFLD) in a rat model. Methods: Eighteen male Wistar rats were allocated to control or experimental groups. A high-fat diet (HFD) with 20% fructose and 2% cholesterol, resembling a common Western diet, was fed to animals in the experimental groups for up to 16 weeks; those in the control group received a regular diet. A 21 MHz UBM system was used to acquire B-mode images at specific times: baseline (T0), 10 weeks (T10), and 16 weeks (T16). The sonographic hepatorenal index (SHRI), based on the average ultrasound image gray-level intensities from the liver parenchyma and right renal cortex, was determined at T0, T10, and T16. The liver specimen histology was classified using the modified Nonalcoholic Steatohepatitis Clinical Research Network NAFLD activity scoring system. Results: The livers in the animals in the experimental groups progressed from sinusoidal congestion and moderate macro- and micro-vesicular steatosis to moderate steatosis and frequent hepatocyte ballooning. The SHRI obtained in the experimental group animals at T10 and T16 was significantly different from the SHRI of pooled control group. No significant difference existed between the SHRI in animals receiving HFD between T10 and T16.Conclusion: SHRI measurement using UBM may be a promising noninvasive tool to characterize early-stage NAFLD in rat models.

Quantitative assessment of image artifacts from root filling materials on CBCT scans made using several exposure parameters

Rabelo, Katharina Alves,Cavalcanti, Yuri Wanderley,de Oliveira Pinto, Martina Gerlane,Melo, Saulo Leonardo Sousa,Campos, Paulo Sergio Flores,de Andrade Freitas Oliveira, Luciana Soares,de Melo, Daniel Korean Academy of Oral and Maxillofacial Radiology 2017 Imaging Science in Dentistry Vol.47 No.3

Purpose: To quantify artifacts from different root filling materials in cone-beam computed tomography (CBCT) images acquired using different exposure parameters. Materials and Methods: Fifteen single-rooted teeth were scanned using 8 different exposure protocols with 3 different filling materials and once without filling material as a control group. Artifact quantification was performed by a trained observer who made measurements in the central axial slice of all acquired images in a fixed region of interest using ImageJ. Hyperdense artifacts, hypodense artifacts, and the remaining tooth area were identified, and the percentages of hyperdense and hypodense artifacts, remaining tooth area, and tooth area affected by the artifacts were calculated. Artifacts were analyzed qualitatively by 2 observers using the following scores: absence (0), moderate presence (1), and high presence (2) for hypodense halos, hypodense lines, and hyperdense lines. Two-way ANOVA and the post-hoc Tukey test were used for quantitative and qualitative artifact analysis. The Dunnet test was also used for qualitative analysis. The significance level was set at P<.05. Results: There were no significant interactions among the exposure parameters in the quantitative or qualitative analysis. Significant differences were observed among the studied filling materials in all quantitative analyses. In the qualitative analyses, all materials differed from the control group in terms of hypodense and hyperdense lines (P<.05). Fiberglass posts did not differ statistically from the control group in terms of hypodense halos(P>.05). Conclusion: Different exposure parameters did not affect the objective or subjective observations of artifacts in CBCT images; however, the filling materials used in endodontic restorations did affect both types of assessments.

Bisabolol-Induced Gastroprotection Against Acute Gastric Lesions: Role of Prostaglandins, Nitric Oxide, and K+ATP Channels

S.B. Bezerra,L.K.A.M. Leal,N.A.N. Pinto,A.R. Campos 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.6

The effects of Matricaria recutita and α-bisabolol, a bioactive component from Chamomile species, were investigated against gastric damage induced by absolute ethanol (96%, 1mL per animal) in rats. The effects of M. recutita extract and α-bisabolol on gastric mucosal damage were assessed by determination of changes in mean gastric lesion area. Mechanistic studies were carried out at with 100mg/kg α-bisabolol. We further examined the possible participation of prostaglandins, nitric oxide, and K+ATP channels in its mechanism. M. recutita reduced gastric damage in all doses tested. α-Bisabolol at oral doses of 50 and 100mg/kg markedly attenuated the gastric lesions induced by ethanol to the extent of 87% and 96%, respectively. Pretreatments with the nitric oxide antagonist N-nitro-l-arginine methyl ester (10mg/kg, i.p.) or with indomethacin, an inhibitor of cyclooxygenase, failed to block effectively the gastroprotective effect of α-bisabolol. Furthermore, the α-bisabolol effect was significantly reduced in rats pretreated with glibenclamide, an inhibitor of K+ATP channel activation. Thus we provide evidence that α-bisabolol reduces the gastric damage induced by ethanol, at least in part, by the mechanism of activation of K+ATP channels.

Quantitative assessment of image artifacts from root filling materials on CBCT scans made using several exposure parameters

Katharina Alves Rabelo,Yuri Wanderley Cavalcanti,Martina Gerlane de Oliveira Pinto,Saulo Leonardo Sousa Melo,Paulo Sérgio Flores Campos,Luciana Soares de Andrade Freitas Oliveira,Daniela Pita de Melo 대한영상치의학회 2017 Imaging Science in Dentistry Vol.47 No.3

Purpose: To quantify artifacts from different root filling materials in cone-beam computed tomography (CBCT) images acquired using different exposure parameters. Materials and Methods: Fifteen single-rooted teeth were scanned using 8 different exposure protocols with 3 different filling materials and once without filling material as a control group. Artifact quantification was performed by a trained observer who made measurements in the central axial slice of all acquired images in a fixed region of interest using ImageJ. Hyperdense artifacts, hypodense artifacts, and the remaining tooth area were identified, and the percentages of hyperdense and hypodense artifacts, remaining tooth area, and tooth area affected by the artifacts were calculated. Artifacts were analyzed qualitatively by 2 observers using the following scores: absence (0), moderate presence (1), and high presence (2) for hypodense halos, hypodense lines, and hyperdense lines. Two-way ANOVA and the post-hoc Tukey test were used for quantitative and qualitative artifact analysis. The Dunnet test was also used for qualitative analysis. The significance level was set at P<.05. Results: There were no significant interactions among the exposure parameters in the quantitative or qualitative analysis. Significant differences were observed among the studied filling materials in all quantitative analyses. In the qualitative analyses, all materials differed from the control group in terms of hypodense and hyperdense lines (P<.05). Fiberglass posts did not differ statistically from the control group in terms of hypodense halos (P>.05). Conclusion: Different exposure parameters did not affect the objective or subjective observations of artifacts in CBCT images; however, the filling materials used in endodontic restorations did affect both types of assessments.

Conventional and digital impressions for complete-arch implant-supported fixed prostheses: time, implant quantity effect and patient satisfaction

Ana Larisse Carneiro Pereira,Vitória Ramos Medeiros,Maria de Fátima Trindade Pinto Campos,Annie Karoline Bezerra de Medeiros,Burak Yilmaz,Adriana da Fonte Porto Carreiro 대한치과보철학회 2022 The Journal of Advanced Prosthodontics Vol.14 No.4

PURPOSE. To evaluate and compare the effect of impression type (conventional vs digital) and the number of implants on the time from the impressions to the generation of working casts of mandibular implant-supported fixed completearch frameworks, as well as on patient satisfaction. MATERIALS AND METHODS. 17 participants, 3 or 4 implants, received 2 types of digital impression methods (DI) and conventional (CI). In DI, two techniques were performed: scanning with the scan bodies (SC) and scanning with a device attached to the scan bodies (SD) (BR 10 2019 026265 6). In CI, the making of a solid index (SI) and open-tray impression (OT) were used. The outcomes were used to evaluate the time and the participant satisfaction with conventional and digital impressions. The time was evaluated through the timing of the time obtained in the workflow in the conventional and digital impression. The effect of the number of implants on time was also assessed. Satisfaction was assessed through a questionnaire based on seven. The Wilcoxon test used to identify the statistical difference between the groups in terms of time. The Mann-Whitney test was used to analyze the relationship between the time and the number of implants. Fisher's test was used to assess the patient satisfaction (P <.05). RESULTS. The time with DI was shorter than with CI (DI, x~=02:58; CI, x~=31:48) (P <.0001). The arches rehabilitated with 3 implants required shorter digital impression time (3: x~=05:36; 4: x~=09:16) (P <.0001). Regarding satisfaction, the DI was more comfortable and pain-free than the CI (P <.005). CONCLUSION. Digital impressions required shorter chair time and had higher patient acceptance than conventional impressions.

Electro-acupuncture and Chinese herbs for treatment ofcervical intervertebral disk disease in a dog

Ayne Murata Hayashi,J?lia Maria Matera,,Tatiana Soares da Silva,Ana CarolinaBrand?o de Campos Fonseca Pinto,S?lvia Renata Gaido Cortopassi 대한수의학회 2007 Journal of Veterinary Science Vol.8 No.1

A non-ambulatory dog with tetraparesis following a pain episode that had evolved over 2 months was submitted for medical treatment and diagnosed with intervertebral disk disease at C3-C4 and dorsal extradural compression at C1-C2 and C3-C4 using myelography and computed tomography. The dog experienced ambulation recovery after 15 days of treatment with only electroacupuncture and Chinese herbal medicine, with marked improvement occurring after only 10 treatments. Six months of followup demonstrated that the dog was stable and had no recurrence of symptoms. Therefore, it was concluded that the combination of electroacupuncture and Chinese herbal medicine was responsible for motor rehabilitation.