Electric-field-induced spin disorder-to-order transition near a multiferroic triple phase point

Jang, Byung-Kweon,Lee, Jin Hong,Chu, Kanghyun,Sharma, Pankaj,Kim, Gi-Yeop,Ko, Kyung-Tae,Kim, Kwang-Eun,Kim, Yong-Jin,Kang, Kyungrok,Jang, Han-Byul,Jang, Hoyoung,Jung, Min Hwa,Song, Kyung,Koo, Tae Yeon Nature Publishing Group 2017 Nature physics Vol.13 No.2

<P>The emergence of a triple phase point in a two-dimensional parameter space (such as pressure and temperature) can offer unforeseen opportunities for the coupling of two seemingly independent order parameters. On the basis of this, we demonstrate the electric control of magnetic order by manipulating chemical pressure: lanthanum substitution in the antiferromagnetic ferroelectric BiFeO3. Our demonstration relies on the finding that a multiferroic triple phase point of a single spin-disordered phase and two spin-ordered phases emerges near room temperature in Bi0.9La0.1FeO3 ferroelectric thin films. By using spatially resolved X-ray absorption spectroscopy, we provide direct evidence that the electric poling of a particular region of the compound near the triple phase point results in an antiferromagnetic phase while adjacent unpoled regions remain magnetically disordered, opening a promising avenue for magnetoelectric applications at room temperature.</P>

Intake levels of dietary polyunsaturated fatty acids modify the association between the genetic variation in <i>PCSK5</i> and HDL cholesterol

Jang, Han Byul,Hwang, Joo-Yeon,Park, Ji Eun,Oh, Ji Hee,Ahn, YounJhin,Kang, Jae-Heon,Park, Kyung-Hee,Han, Bok-Ghee,Kim, Bong Jo,Park, Sang Ick,Lee, Hye-Ja BMJ Publishing Group Ltd 2014 Journal of medical genetics Vol.51 No.12

<P><B>Background</B></P><P>A low serum level of high-density lipoprotein cholesterol (HDL-C) is a risk factor for cardiovascular disease. Proprotein convertase subtilisin/kexin type 5 (<I>PCSK5</I>) modulates HDL-C metabolism through the inactivation of endothelial lipase activity.</P><P><B>Methods</B></P><P>Therefore, we analysed the effects of <I>PCSK5</I> on HDL-C and investigated the association between genetic variation in <I>PCSK5</I> and dietary polyunsaturated fatty acids (PUFAs) intakes in Korean adults and children. This population-based study which was conducted in South Korea included 4205 adults (43% male) aged 40–69 years and 1548 children (48.6% boys) aged 8–13 years. Dietary intake was assessed using a semiquantitative food frequency questionnaire in adults and modified 3-day food records in children.</P><P><B>Results</B></P><P>After adjustments for age and body mass index, we identified a significant association between SNP rs1029035 of the <I>PCSK5</I> gene and HDL-C concentrations specifically for men in both populations (adults, p=0.004; children, p=0.003; meta, p=7×10<SUP>−4</SUP>). Additionally, the interaction between the <I>PCSK5</I> rs1029035 genotype and dietary polyunsaturated fatty acids intake influenced serum HDL-C concentrations in men (adults, p=0.001; children, p=0.008). The deleterious effect of the C allele on serum HDL-C was present only when dietary PUFA intake was less than the dichotomised median level (adults, p=0.011; children, p=0.001). Serum HDL-C concentrations were decreased in men with the C allele genotype and low consumption of dietary PUFA including n-3 and n-6.</P><P><B>Conclusion</B></P><P>According to these results, men carrying of the C allele were associated with low HDL-C concentrations and might exert beneficial effects on HDL-C concentrations following consumption of a high-PUFA diet.</P>

부모의 사회경제적 수준 (가구 월수입 부모 교육수준)과 초등학교 6학년 학생의 과체중 및 식습관 식사 질과의 관계

장한별(Jang Han Byul),박주연(Park Ju Yeon),이혜자(Lee Hye-Ja),강재헌(Kang Jae Heon),박경희(Park Kyung-Hee),송지현(Song Jihyun) 韓國營養學會 2011 Journal of Nutrition and Health Vol.44 No.5

본 연구는 부모의 사회경제적 수준과 초등학교 6학년 자녀의 과체중 위험도 식습관 식사 질과의 관계에 대하여 알아보고자 하였으며 그 결과는 다음과 같다. 1) 어머니 교육수준이 낮은 여학생 집단이 비교 집단에 비해 과체중의 위험도가 1.91배 높았다. 하지만 남학생의 경우에는 과체중 위험도와 사회경제수준 간에 유의성이 없었다. 2) 남녀 모두 수입 및 부모의 교육수준이 낮은 집단에서 과일류 섭취량이 유의적으로 낮은 것으로 나타났으며 여학생의 경우 이와 함께 가구 월수입 및 부모의 교육수준이 낮은 집단에서 어패류의 섭취량도 유의적으로 낮았다. 3) 1일 평균 영양소 섭취량을 비교한 결과 여학생의 경우 가구 월수입 및 부모의 교육수준이 낮은 집단에서 총 섭취량과 식물성 식품의 섭취가 유의적으로 낮았으며 이와 함께 탄수화물 비타민 C 칼륨 식이 섬유의 섭취도 유의적으로 낮게 나타났다. 4) 여학생의 경우 아버지의 교육수준이 낮은 집단에서 높은 집단 보다 탄수화물을 통하여 섭취하는 에너지의 비율은 낮았던 반면 지방의 비율은 유의적으로 높았다. 하지만 남학생의 경우 가구 월수입 및 부모의 교육수준에 따른 열량 및 영양소 섭취량에서 유의적인 차이가 없었다. 5) 가구 월수입 및 부모의 교육수준이 낮은 집단에서 EAR 미만으로 영양소를 섭취하는 대상자 비율이 높았다. 남학생은 월수입이 낮은 집단에서 나이아신 철분 섭취가 EAR 보다 부족한 학생비율이 높았으며 부모의 교육수준에 따라서는 유의적인 차이가 없었다. 여학생은 사회경제적 수준이 낮은 집단에서 인의 섭취가 EAR 미만인 대상자가 비율이 유의적으로 높았고 이와 함께 부모 교육수준이 낮은 집단에서 나이아신과 비타민 B6의 섭취량이 EAR 보다 부족한 비율이 높았다. 6) 여학생의 경우 가구 월수입에 따른 비교에서 가구 월수입이 낮은 집단에서 라면의 섭취 빈도가 높은 것으로 나타났으며 부모의 교육수준에 따른 비교에서는 교육수준이 낮은 집단에서 남녀 모두 아침 식사 결식 횟수가 높고 라면의 섭취 빈도가 높은 것으로 나타났다. 7) 여학생의 경우 가구 월수입 및 부모의 교육수준이 낮은 집단에서 식품섭취 다양성과 균형성이 모두 비교 집단에 비하여 낮게 나타났다. 하지만 남학생의 경우 가구 월수입 및 부모의 교육수준에 따른 유의적인 차이가 관찰되지 않았다. 본 연구를 통하여 부모의 사회경제적 수준은 여학생의 식습관과 식사의 질에 영향을 미치는 것으로 나타났다. 부모의 낮은 사회경제적 수준은 자녀의 바람직하지 않은 식습관과 낮은 식사의 질과 관련되어 있었으며 이는 영양소 섭취량에도 영향을 미치고 있었다. 또한 어머니 교육수준은 여학생의 과체중 위험도에 영향을 미치는 것으로 나타났다. 따라서 사회경제적 수준이 낮은 집단에 대한 건강한 식습관과 체중 관리를 위한 교육 및 영양 정책이 필요하다. This study investigated the association among parental socioeconomic level overweight and eating habits with diet quality in Korean sixth grade school children. A 3-day dietary survey was conducted and a questionnaire and anthropometric data were collected from the Korean child obesity cohort (320 boys and 345 girls). The children were classified into two groups (low or high level) based on monthly household income and paternal and maternal education status. Lower maternal education status was associated with a higher risk for overweight in girls (odd ratio 1.91; 95% confidence interval 1.07-3.44) whereas belonging to a higher socioeconomic group in terms of parental income or parental education level resulted in the consumption of significantly more fruit. Boys did not show significant differences in the intake of most nutrients or diet quality regardless of socioeconomic status. However girls in the lower socioeconomic group had a lower food habit score (higher frequency of breakfast skipping and ramen noodle consumption) diet quality and intake of nutrients (carbohydrate vitamin C potassium and fiber) than those in the higher socioeconomic group. Therefore future nutrition policies and interventions should support parents and children with lower socioeconomic status to develop health-related behaviors that may prevent childhood overweight.

Probabilistic bit-stream generation using telegraphic switching of magnetic tunnel junction

Jin-byul Jang,Gi Yoon Bae,Ye-chan Hwang,Jaewon Jang,Wanjun Park 한국진공학회 2019 한국진공학회 학술발표회초록집 Vol.2019 No.8

에지 방향성 히스토그램 데이터를 이용한 손 형상 인식

김장운(Jang-Woon Kim),김송국(Song-Gook Kim),장한별(Han-Byul Jang),배기태(Ki-Tae Bae),이칠우(Chil-Woo Lee) 한국정보과학회 2006 한국정보과학회 학술발표논문집 Vol.33 No.2B

본 논문에서는 복잡한 배경을 가진 영상에서 손 영역을 안정적으로 검출, 손 형상을 인식하여 그림 맞추기 응용 프로그램을 제어하는 시스템에 대해 기술한다. 피부색의 컬러 정보를 이용하여 손 영역만을 추출한 후 핑거 팁 템플릿매칭을 사용하여 손가락 끝점을 찾아낸다. 또한 손 영역의 에지 방향성 히스토 그램을 구하여 얻어진 정보를 바탕으로 주성분 분석법을 사용하여 손 형상을 인식한다. 최종적으로 인식된 손 형상 정보와 손가락 끝점 추적을 이용한 명령어 실행으로 그림 맞추기 응용 프로그램을 제어 한다. 본 논문에서 제안한 알고리즘으로 그림 맞추기 응용 프로그램 제어에 적용한 결과 안정적인 실험 결과를 얻을 수 있었고, HCI 분야에서 다양하게 활용될 수 있음을 확인하였다.

Intake and blood concentrations of folate and their association with health-related behaviors in Korean college students

Han-Byul Jang,Young-Hee Han,Chandrika J Piyathilake,Heon Kim,Taisun Hyun 한국영양학회 2013 Nutrition Research and Practice Vol.7 No.3

The purpose of this study is to assess folate intake, and serum and red blood cell (RBC) folate concentrations, and investigate the association between folate status and health-related behaviors among Korean college students. A total of 169 students, aged between 18 and 27 years, participated in this study. Dietary intake data were collected by trained interviewers using a 24-hour recall method for three non-consecutive days in 2009. Information on health-related behaviors was obtained by a self-administered questionnaire. Serum and RBC folate concentrations were measured by microbiological assay. The average intakes of folate were 456 μgDFE and 347 μgDFE in male and female students, respectively. While the average serum folate concentration was significantly lower in male students (8.9 ng/mL) compared to female students (12.5 ng/mL), RBC concentrations were not significantly different between male (398.6 ng/mL) and female students (405.3 ng/mL). In male students, low serum folate concentrations were associated with total folate intake less than the Estimated Average Requirement, non-use of folic acid supplements, smoking, alcohol drinking at least once a week and low physical activity. In female students, low serum folate concentrations were associated with smoking and alcohol drinking at least two drinks at a time and BMI ≥ 25. Alcohol drinking and low physical activity were also associated with low RBC folate concentrations in both male and female students. In order to improve folate nutritional status of college students, the practice of desirable health-related behaviors, such as non-smoking, moderate alcohol drinking, regular physical activity, and maintenance of healthy BMI should be encouraged along with consumption of folate-rich foods and supplements.

한방치료를 통한 월경주기 회복 후 배란유도를 통해 임신과 출산에 성공한 조기난소부전 환자 치험 1례

장새별 ( Sae Byul Jang ),정은혜 ( Eun Hye Jung ),최경희 ( Kyung Hee Choi ),유동열 ( Dong Youl Yoo ) 대한한방부인과학회 2014 大韓韓方婦人科學會誌 Vol.27 No.3

bjectives: This study aims to research correlation of the malondialdehyde level in urinalysis with cold hypersensitivity. Methods: We studied 128 patients visiting ○○ Korean Hospital from March,2013 to May, 2013. The subjects were categorized into two groups: cold hypersensitivity group (n=46) and control group (n=79). Patients in cold hypersensitivity group had been stressed because of severe cold hypersensitivity. First, We investigated the difference of the level of malondialdehyde between two groups. In addition, temperature of the two points, ST32 and LR3, was measured by using Digital Infrared Thermal Imaging (DITI) to find out whether the extent of cold hypersensitivity is related to the level of malondialdehyde. Results: There is no different characteristics between two groups. The average of malondialdehyde in cold hypersensitivity group (1613.15±1260.71) is significantly higher than in control group (1170.01±1015.66)(p=0.04). But there is no correlation between level of malondialdehyde and the extent of cold hypersensitivity (r=-0.22,p=0.13). Conclusions: Although the level of malondialdehyde in cold hypersensitivity group is higher than in control group, there is no significant correlation between level of malondialdehyde and the extent of cold hypersensitivity.

테이블 탑 디스플레이 인터페이스를 사용한 증강현실 요리 시스템

장한별(Han-Byul Jang),송대현(Dae-Hyeon Song),김장운(Jang-Woon Kim),이칠우(Chil-Woo Lee) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.7

Cooking is necessary subject for life and popular subject taken interests. All people like delicious food and sometimes try to make food. But in case of kids, cooking is difficult because there is some danger to use cooking tools like oven and knife. AR cooking system using table top display interface is an virtual cooking environment for kids without danger. AR technology gives more realistic sense and table top display interface make more intelligent interactions.

계지복령환의 효능에 대한 국내외 실험연구 동향 분석

장새별 ( Sae Byul Jang ),백선은 ( Seon Eun Baek ),최경희 ( Kyung Hee Choi ),유정은 ( Jeong Eun Yoo ) 대한한방부인과학회 2016 大韓韓方婦人科學會誌 Vol.29 No.2

Objectives: Gyejibokryeong-hwan (GBH), a traditional Korean herbal medicine, has been widely used for the treatment of the blood stasis syndrome. This study is purposed to analyze the experimental research trend of GBH in Korea for developing further research plan. Methods: A search of Korean research database-Oasis, RISS and KISS- and Pubmed was carried out for publications until 2015, for the words, ``Guizhifulingwan``, ``Gyejibokryeonghwan``, or ``Keishibukuryogan``. Then study selection is conducted according to PRISMA guidelines, studies not related or using modified formula or administered for human are excluded, 48 studies are included in this review, finally. We analyzed studies by research method, subject, outcome measure, and result of the study. Results: There were 31 in vivo studies about the effect of GBH on platelet aggregation, anti-oxidant, blood viscosity, and hypercholesterolemia, etc. 12 in vitro studies were about the effect of GBH on the cervical carcinoma, chronic kidney disease, uterine myoma, hepatocarcinoma, atherosclerosis, cancer chemo-prevent. 9 ex vivo studies were about the effect of GBH on the platelet aggregation, chronic kidney disease, ovaulatory disorder, and rheumarthritis. Conclusions: We proposed the translational research of GBH involving scientific discoveries and developing practical applications by investigating the concept of blood stasis syndrome in terms of current physiopathological mechanism.

백굴채 추출물이 MDA-MB-231 유방암 세포주에서 세포사멸에 미치는 효과

장새별 ( Sae Byul Jang ),유동열 ( Dong Youl Yoo ) 대한한방부인과학회 2015 大韓韓方婦人科學會誌 Vol.28 No.2

Objectives: In this study, we investigated the anti-proliferative and apoptosis inducing effect of water extract of Chelidonium majus (CM) on human breast cancer cell MDA-MB-231. Methods: The MTT assay was used to assess cell proliferation. The expression of apoptosis related gene was assessed by quantitative Real-time PCR. Cell apoptosis detected by flow cytometry using Annexin-V/PI staining. Results: Our data revealed that CM inhibited the cell growth in a dose dependent manner (0, 62.5, 125, 250, 500 μg/ml). CM increased mRNA expression of pro-apoptotic genes Bax, caspase-3, and caspase-9. Annexin-V/PI staining assays revealed that apoptosis-induced cell death increased in a dose-dependent manner in cells. Conclusions: CM induces cell death in MDA-MB-231 human breast cancer cell and shows potentials for use in cancer therapy as apoptosis-inducing agent.