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류마티스성 심장판막질환, 우심방혈전 및 대동맥 협착증과 합병된 만성 혈전색전성 폐동맥고혈압 1예
유근배,심준,임양희,이진화,신길자 梨花女子大學校 醫科大學 醫科學硏究所 1998 EMJ (Ewha medical journal) Vol.21 No.4
폐동맥 혈전색전증은 비교적 드문 질환으로 주로 심부 정맥혈전에서 발생하는 것으로 알려져 있으며 류마티스성 심장판막질환을 가진 경우 합병되는 우심방 혈전이 드물게 폐혈전색전증의 원인이 될 수 있는데, 저자들은 대동맥의 동맥경화성 협착증을 동반한 류마티스성 심판막질환 환자에서 우심부전 및 우심방혈전에서 발생한 만성 혈전색전성 폐동맥고혈압1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Most pulmonary thromboemboli arise from the deep vein thrombosis, which have complete clinical and at least near complete roentgenographic and angiographic resolution within four to six week of the acute event. But chronic pulmonary hypertension and cor pulmonale from unresolved pulmonary embo-lism complicate acute embolic episode with a frequency of less than 1 percent. Rarely pulmo-nary thromboemboli can result from right atrial thrombi. We experienced a case of chronic thromoboembolic pulmonary hypertension, which wrose from right atrial thrombi in the patient with rheumatic valvaular heart disease and thoracic aorta atherosclerotics stenosis.
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대구·경상북도 초등양호교사들의 구강보건 인식도에 관한 조사
송근배,김달호,신영림 慶北大學校 齒科大學 1993 慶北齒大論文集 Vol.10 No.1
대구시 및 경상북도지역 초등양호교사들의 구강보건에 관한 지식습득경로, 구강보건에 대한인식정도 및 학교구강보건관리에 대한 역활인식도등을 조사하여 지역실정에 맞는 학교구강보건교육 및 교육내용을 계획하고 적절한 학교구강보건사업의 운영방법설정에 기초적인 자료를 마련할 목적으로 대구 및 경상북도지역내에 근무하는 초등양호교사 176명을 대상으로 설문지를 이용하여 조사분석한 결과 다음과 같은 결론을 얻었다. 구강보건에 관한 지식습득경로는 대구시 초등양호교사들은 보수교육(78.8%)이 가장 높았고 경상북도 양호교사들에서는 신문, 잡지의 기사나 홍보책자(72.9%)라는 답변이 가장 많아 체계적인 보수교육이 필요한 것으로 나타났다. 구강위생을 관리하는 목적으로 치아우식증 및 치주질환예방에 대해서는 대체적으로 중요하게 생각하고 있었으며, 치아우식증을 예방할수 있는 효과적인 방법에 대한 견해는 불소의 이용이나 치면열구전색재의 사용보다 정기적인 치과방문이나 당분섭취를 제한한다가 더 높게 나타났다. 불소에 대한 지식도 및 치주질환에 대한 인식도는 대구시, 경상북도 초등양호교사들에서 약간의 차이는 있으나 전반적으로 단편적이고 부정확한 지식을 가지고 있어서 정확한 지식의 전달을 위한 교육과정이나 홍보책자의 개발이 필요하였다. 학교구강보건관리에 있어서의 양호교사의 역활에 대해서는 상당히 긍정적인 의견을 가지고 있었으나 경상북도 초등양호교사들중 불소용액양치사업을 관리감독한다는 항목에 대해서는 약 40%정도만이 찬성하고 있어서 군단위이하 국민학교 불소용액양치사업의 시행에 문제점으로 지적되었다. 대구시 초등양호교사들의 전반적인 구강보건에 관한 지식수준정도는 서울 및 부산지역의 초등양호교사들과 비슷하였으나, 경상북도 초등양호교사들에 있어서는 부족하여 체계적인 지식전달의 대책마련이 시급한 것으로 나타났다. The oral health knowledge and attitudes of elementary school nursing teachers can play a critical and important role in assuring that elementary school teachers, children and their parents have current, scientifically accurate oral health information and behaviors. 176 nursing teachers at elementary schools in Taegu city and Kyungpook province were surveyed to determine their sources of information about oral health and their knowledge and attitudes about dental disease and its prevention. Data were collected using a 7-item, mailed questionnaire(67% reponse rate). The most frequently cited sources of information about dental health were newspapers or magazines(75.0%), followed by college curriculum(62.5%). The most important reason for good oral hygiene was preventing dental caries in urban nursing teachers and preventing periodontal disease in rural nursing teachers. The knowledge about fluorides and preventive methods of dental caries and periodontal disease were incccurate and incomplete in both area, but knowledge levels of urban nursing teacher's were higher than those of rural's. Many of nursing teachers agreed to accept their responsibility and role for promote oral health in the elementary school except the supervising of fluoride mouth rinsing program. Nursing teachers may not have sufficient dental knowledge to teach dental health and greater attention to improve the oral health knowledge and attitudes of nursing teachers in needed.
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김영숙,신영림,송근배,김영진 慶北大學校 齒科大學 1992 慶北齒大論文集 Vol.9 No.1
The purpose of this study was to investigate the effects of tooth enamel dissolution by commercial beverages. Five kinds of beverages(cola, cider, aquarius, boribori and sunkist orange) were selected for test medium and sixteen of extracted 3rd molar were used for tooth enamel specimens. The acidity of each beverage was determined with pH meter and the concentration of total glucose was checked with Glucose kit and U-V spectrophotometer. The dissolved calcium was determined by Atomic Absoprtion Spectrophotometer and the change of enamel surfaces were observed with Scanning Electron Microscopy(× 400 & × 1,000 magnification). All collected data were analyzed by one-way & two-way ANOVA in SPSS/PC^+ program. The obtained results were as follows: 1. The major containing acid type of cola beverage was phosphoric acid but the other beverages(cider, aquarius, boribori and sunkist) were citric acid. The pH of each beverage was lowest in cola and sport drink, cider, boribori, fruit juice in ascending order(F=205.85, p<0.001), the average pH of 5 kinds of beverage was 2.84 ±0.04, all beverages used in this experiment were low enough to decalcify the tooth enamel. The total glucose concentration of each beverage was 2.74% in aquarius, 2.78% in cider, 3.96% in sunkist, 4.23% in boribori and 4.27% in cola. 2. The average dissolved calcium concentration in 5cc of beverage was 1.54±0.12ppm/5㎖ of HNO_3 in cola, 1.76±0.38ppm in sunkist, 1.90±0.09ppm in boribori, 3.03±0.09ppm in aquarius, 3.59±0.38ppm in cider and the final calcium contents, which is extrated original calcium contents from total calcium contents after 120 minutes were highest in cola(1.27ppm) and aquarius(1.02ppm), cider(0.58ppm), sunkist(0.45ppm), boribori(0.33ppm) in the order(p<0.05). 3. The direct proportional relationship was not found between the degree of surface change on Scanning Electron Microscopy and the amount of dissolved calcium per immersion time. But the more the immerging time was lengthened, the more surface change was observed. The surface change of 120 minutes group was more remarkable than 30 and 60 minutes immerged group in each beverage.
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연구논문 : Aspergillus oryzae로 발효한 자색당근을 첨가한 발효유의 품질 및 관능 특성에 관한 연구
신배근 ( Bae Keun Shin ),강선아 ( Suna Kang ),한정인 ( Jung In Han ),박선민 ( Sunmin Park ) 한국식생활문화학회 2015 韓國食生活文化學會誌 Vol.30 No.3
In this study, we compared the organoleptic and other qualities of fermented milk containing 10 or 15% purple carrot extract that had either been previously fermented with Aspergillus oryzae or not fermented. Fermentation characteristics, pH, chromaticity, viscosity, viable cell counts, and sensory evaluations were measured. The pH and acid values did not differ between purple carrot extract fermented with Aspergillus oryzae and non-fermented extract. Viable cell counts were significantly higher in 15% purple carrot extract fermented with Aspergillus oryzae compared to the control after fermentation. Regarding characteristic changes, purple carrot extract fermented with Aspergillus oryzae group showed a lower red value but higher yellow value compared with non-fermented purple carrot extract due to heat-sterilization. Both fermented and non-fermented extract groups showed significantly increased viscosity compared to control. In the sensory evaluation, 15% purple carrot extract fermented with Aspergillus oryzae showed the highest score. In conclusion, addition of 15% purple carrot extract fermented with Aspergillus oryzae resulted in a superior fermented milk product.
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Bae Dong Su,Kim Chunghun,Lee Hunsu,Khater Omar,Kim Keun Su,Shin Homin,이건홍,Kim Myung Jong 나노기술연구협의회 2022 Nano Convergence Vol.9 No.20
Highly crystalline and few-walled boron nitride nanotubes (BNNTs) had been synthesized by laser ablation using only ammonia borane as a precursor. As a molecular precursor, ammonia borane supplied both B and N atoms with a ratio of 1:1, and BNNTs were formed via the homogeneous nucleation of BN radicals, not the growth from boron nano-droplets, which is a generally accepted growth mechanism of the laser-grown BNNTs. Owing to the absence of amorphous boron impurities, the van der Waals interaction among BNNTs became effective and thus a BNNT fibers was formed spontaneously during the BNNT synthesis. The BNNT growth and the subsequent fiber formation are found to occur only at high pressures of a surrounding gas. The mechanism behind the critical role of pressure was elucidated from the perspective of reaction kinetics and thermal fluid behaviors. A polarized Raman study confirmed that the BNNT fiber formed exhibits a good alignment of BNNTs, which implies great potential for continuous production of high-quality BNNT fibers for various applications.
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Xylitol 이 첨가된 0.05% 불화나트륨 양치액이 인공초기우식병소의 재석회화에 미치는 영향
신영림,송근배 대한구강보건학회 1998 大韓口腔保健學會誌 Vol.22 No.2
The purpose of this study was to investigate the effect of xylitol containing mouthrinse on remineralization of early caries-like lesions in situ model. One hundred twenty extracted first premolars for orthodontic treatment were collected and early caries-like lesions (ECL) were artificially created using 0.1M lactic acid-sodium hydroxide buffer (pH=4.0). Enamel specimens with ECL were mounted on the removable lower appliances with sticky wax. Five conveniently selected subjects wore the appliance for three separate 21 days without any treatment, with daily exposure to 0.05% NaF solution for 1 minute and daily exposure to 10% xylitol containing 0.05% NaF solution for 1 minute. Fluoride and xylitol-free dentifrice was used for all regimens. There were two weeks of wash-out period between three consecutive experiments to prevent carry-over effect. Surface and cross-sectional microhardness were measured with Vicker's microhardness tester. The change of enamel surface were also observed with Energy Dispersive X-ray Spectrum (EDXS) and scanning electron microscopy. Differences in each group were compared by one-way ANOVA and Duncan' s multiple range test. Corresponding p-values were considered significant at values <0.05. Surface microhardness values after intra-oral exposure (IOE) were significantly higher than ECL (p<0.05), but there were no differences between saliva, fluoride and xylitol-F group. As for surface microhardness after a controlled acid challenge, fluoride and xylitol-F group were higher than saliva exposure group (p<0.05). When the values of surface microhardness after ART were converted into percentage ratio with the values of each IOE group, xylitol-F group was highest among three groups (p<0.05). Cross-sectional microhardness at 25㎛, 45㎛ depth from enamel surface were higher in IOE than ECL (p<0.05), but not at 65㎛ depth. When the morphologic changes of surface after IOE were observed with SEM, there found some evidences of remineralization with relatively homogeneous surface pattern and granules. All the findings presented support the conclusion that saliva was good enough to remineralize the early caries-like lesion if the subject could keep good oral hygiene. Fluoride mouthrinsing could provide a resistance from secondary acid attack. This study did not focus on the anti-cariogeruc effect of xylitol but on the reversals of early carious like lesions. The author suggest that true xylitol effects on remineralization of early caries like lesion are a clinical reality, whatever their mechanisms.
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Aromatic retinoid(Ro10-9359)가 백서 악하선암에 미치는 영향에 관한 실험적 연구
권배근,신형식 원광대학교 치의학연구소 1990 圓光齒醫學 Vol.1 No.1
The purpose of this study was to evaluate the effects of Aromatic Retinoid(Ro 10-9359) on the carcinogenesis induced by implantation of 9,10-dirnethy-1,2-benzanthracene(DMBA) on the submandibular gland in rats. Forty-six male rats of Sprague-Dawley were divided into three groups. Group 1 (24 animals) were implanted with 4∼6㎎ pellet of powdered DMBA in exposed submandibular glands. Group 2 (16 animals) were treated by the same methods as Group 1, and supplied with AR in soy bean milk. as a vehicle at 17th and 18th week (200㎎/㎏/day/3 times weekly). Group 3 (6 animals) were untreated. All animals were sacrificed at 8th, 10th, 12th, 16th, 17th, and 18th week after experiments, submandibular gland were removed, and then fixed in the 10% formalin, sectioned in paraffin and stained with the Hematoxylin-Eosin, Van Gieson and Periodic Acid Schiff, and then histopathologic change were obtained. The results were as follows 1. DMBA impantation(group 1) showed epidermal cyst with dysplasia, carcinoma in situ at 8th week, early invasive squamous cell carcinoma at 10th week, well differentiated squamous cell carcinoma at 12th week, moderately differentiated squamous cell caricinoma at 16th weeks, and poorly differentiated squamous cell carcinoma at 17th week. 2. AR treated group (group 2) showed a little regression of tumor size at 17th, 18th week were more than those in group 1. 3. AR treated group showed reduction of keratin formation, and severe necrosis at 17th week. 4. AR treated group showed necrosis or autolysis which involves from connective tissue to deep muscle layer and severe inflammatory cell infiltration were more than those in group 1th at 18th week. 5. In PAS stain, there were positive reaction in epidermal layer at carcinoma in situ but negative at necrotic tissue of AR treated group. 6. In Van Gieson stain, collagen fibers showed positive reaction at stroma of proliferating tumor in group 1, but negative at necrotic tissue of group 2. In summery, retinoid exhibited a regressive effect on DMBA induced carcinoma of submandibular gland in rats. The mechanism of effect of retinoid may be associated with extensive autolysis or necrosis at the tumors, with the great loss of keratin, and incresed of cellular immunity.
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