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하배진,남천석,박은경,강금석 신라대학교 자연과학연구소 2006 自然科學論文集 Vol.15 No.-
In the present study the hepatoprotective and antioxidative effects of Epimedium koreanum (EK) and Salicornia herbacea (SH) were investigated against carbon tetrachloride (CCl_(4))-induced liver damage in rats. EK and SH (100 mg/kg) were administered into rats intraperitoneally (i.p) for 2 weeks. After CCl_(4) a dose of 3.3ml/kg was administered to induce hepatotoxicity. This antioxidative effects of EK and SH on CCl_(4) -treated rats were measured through the activity of Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) in serum and Superoxide dismutase (SOD), Catalase (CAT) in liver tissue. EK or SH-administered and CCl_(4) -treated (ECT or SCT) groups showed inhibitory effects in AST and ALT activities compared to CCl_(4) -treated control (CTC) group. SOD and CAT in ECT and SCT groups were increased compared to those of CTC group.
강금석,남천석,김인덕,권륜희,이동찬,허예영,하배진 신라대학교 자연과학연구소 2007 自然科學論文集 Vol.16 No.-
The effects of Laminaria japonica fucoidan extract (LJFE) on the biochemical parameters of lipid-related function were investigated in liver and serum of CCl_(4)-treated rats. LJFE of 100 mg/kg concentration was intraperitoneally administered into rats at dose of 1.5 ml/kg for 14 days. On the day 15, 3.3 ml/kg of CCl_(4) dissolved in olive oil (1:1) was injected 12 hours before anesthetization. We examined the lipid-related functions and enzyme activitys by measuring the levels of total cholesterol (TC), triglyceride (TG), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) in serum. The results showed that CCl_(4) treatment increased the high values of TG, LDH and ALP decreased the low values of TC but LJFE pretreatment decreased the high values of TG, LDH and ALP to the low values, increased the TC. It was suggested that LJFE can be used as the potential candidate for the lipid-metabolism natural supplement.
김수일,나은우,김덕용,배하석 한국전문물리치료학회 2003 한국전문물리치료학회지 Vol.10 No.2
The purpose of this study was to provide information on driving characteristics in persons with spinal cord injury through basic statistic analysis of the survey results. The survey was administered to 44 drivers with spinal cord injury. The subjects' general, neurologic and driving characteristics were analyzed, as well as the degree of difficulty in using their vehicles between tetraplegia and paraplegia. The results were as follows: thirty-five (79.6%) of forty-four respondents was men. The average age was 35.0 years old and the age at the time of injury was 29.0 years old. Their neurologic characteristics were tetraplegics 12 (27.3%) and paraplegics 32 (72.2%). Among complete lesions, the highest level those who could drive independently was C7. All the vehicles were equipped with special devices, including "power steering", "automatic transmission" and "hand controls". The vehicles for cervical cord injury were equipped with "grip bars" as well as for the degree of difficulty in using their vehicles, all the subjects felt that "moving the wheelchair in and out of their vehicles" was too difficult for them to do. We suggest that the driver training should be an essential part of the rehabilitation program for patients with spinal cord injuries to maximize their mobility in the community. This training seems to be essential in order to modify the standards of the Handicapped Drivers Ability Test and to aid the driver rehabilitation program in the health insurance payment system. Also, the driver rehabilitation training program should include instruction in that moving wheelchairs in and out of vehicles.
건강검진 수진자를 대상으로 한 충남 서북부 지역의 바이러스 간염 표지자 양성률 및 간수치 이상에 관한 연구
김석배 ( Suk Bae Kim ),이원경 ( Won Kyung Lee ),최훈 ( Hoon Choi ),김소미 ( So Mi Kim ),노란 ( Rhan Noh ),강하얀 ( Ha Yan Kang ),이상석 ( Sang Suk Lee ),라성수 ( Sung Soo Ra ),공재환 ( Jae Hwan Gong ),신현덕 ( Hyun Duk Shin ) 대한소화기학회 2009 대한소화기학회지 Vol.53 No.6
목적: 간염 바이러스 표지자의 양성률은 지역과 대상 집단의 성격에 따라서 차이가 있는데 최근 건강검진이 확산되면서 유병률을 조사하는 데 많은 도움이 되고 있다. 이에 저자들은 본원에서 건강검진을 받은 충남 서북부 지역의 성인들을 대상으로 B형과 C형 간염 바이러스 양성률과 간기능 이상률을 조사하였다. 대상 및 방법: 2002년 1월부터 2006년 12월까지 단국대학교 건강검진센터에서 검진을 받은 40,112명을 대상으로 하였다. 이들의 자료들 중 HBsAg, anti-HBs, anti-HCV, AST, ALT 등을 후향 분석하였다. 결과: 총 40,112명 중 남자가 22,936명이었고 여자는 17,176명이었으며 평균 나이는 42.9±11.2세였다. 전체 대상군의 HBsAg 양성률은 4.2%였고 성별로 보면 남자 4.5%, 여자 3.7%로 남자가 여자보다 유의하게 높았다(p<0.001). 연령에 따른 HBsAg 양성률은 40대가 5.1%로 가장 높았고 그 다음으로 10대(4.2%), 30대(4.1%), 50대(4.1%), 20대(3.3%)의 순이었다. 전체 대상군의 anti-HBs 양성률은 65.1%였고 성별로 보면 남자 64.8%, 여자 65.4%로 성별 간의 유의한 차이는 보이지 않았다. 연령에 따른 anti-HBs 양성률은 10대가 80.3%로 가장 높았고 그 다음으로 40대(68.5%), 20대(67%), 30대(66.6%)로 연령이 증가할수록 감소하는 소견을 보였다(p<0.001). 전체 대상군의 anti-HCV 양성률은 0.7%였고 성별로 보면 남자 0.7%, 여자 0.6%로 유의한 차이는 보이지 않았다. 이들을 추적검사한 결과 만성 C형 간염의 유병률은 0.09%였다. 전체 대상군 중 LFT 이상을 보인 사람은 11.4%였다. 이를 HBsAg 여부에 따라 구분해 보았을 때 HBsAg 양성인 군은 21.7%가 HBsAg 음성인 군은 10.9%가 LFT 이상을 보여 유의한 차이를 보였다(p<0.001). 그리고 anti-HCV 양성인 군은 28.6%가, 만성 C형 간염군은 63.2%가 LFT 이상을 보여 전체군보다 월등히 높았다. AST, ALT의 평균값도 만성 B형 간염, 만성 C형 간염군이 전체군에 비해서 의미 있게 높았다(p<0.001). 결론: 충남 서북부 지역의 HBsAg, anti-HCV 양성률은 각각 4.2%, 0.7%로 전국보다 낮았다. 그러나 10대 및 20대에서의 HBsAg 유병률은 아직도 높아서 이를 줄이기 위한 노력이 필요할 것으로 보인다. Background/Aims: We studied the prevalence of chronic hepatitis B, C and abnormality on liver function among the population in northwest area of Chungnam. Methods: We have reviewed 40,112 adults who had received medical examination at health promotion center in Dankook university hospital. We studied them retrospectively about HBsAg, HBsAb, anti-HCV, and liver function test (LFT). Results: Among the study subjects, 22,936 men and 17,176 women were involved. The overall seroprevalence of HBsAg was 4.2%. The prevalence in men (4.5%) was higher than that of women (3.7%) (p<0.001). The seroprevalence of HBsAg in their age was 5.1% in the 5th decade, 4.2% in the 2nd decade, 4.1% in the 4th decade, and 4.1% in the 6th decade. The overall seroprevalence of HBsAb was 65.1%. The overall seroprevalence of anti-HCV was 0.7%. After we reexamined them with HCV RNA or RIBA (Recombinant Immunoblot Assay), the prevalence of chronic hepatitis C was 0.09%. The LFT abnormality in total subjects was 11.4%. The LFT abnormality of chronic hepatitis B and C subjects was 21.72% and 63.2%. Conclusions: The prevalence of chronic hepatitis B and C was lower than that of previous studies. The prevalence of chronic hepatitis B in the 2nd decade was still high. (Korean J Gastroenterol 2009;53:355-360)
A Study of the Airport Model Based on Security Risk
Yong-Suk Kang,Yang-Ha Chun,Yong-Tae Shin,Jong-Bae Kim 보안공학연구지원센터 2014 International Journal of Software Engineering and Vol.8 No.11
The recent APT attacks including cyber terror are caused by a high level of malicious codes and hacking techniques. The substantive problem is that there are frequent cases in which accounts are seized by malicious hackers and servers are attacked due to a high dependence on the ID/Password system, or account information is exposed through new malicious codes that are not detected by vaccines. This implies that essentially, advanced security management is required, from the perspective of 5A. According to the consideration and research on the big information Security accident cases that have occurred over the last 5 years, the paralysis of A-Bank networks resulted from the non-observance of account management policy, even though there was an account management process, and the user information leakage of B-Portal was caused by APT attacks using malicious codes, but it could prevent it by using the Multi-Factor certification of users to have access to DB or server using OTP, rather than ID/Password. Also, the customer information leakage of C-Capital wouldn’t occur, if it deleted the accounts of employees who resigned, in accordance with security policy, and the customer information leakage of KT agencies could be prevented in advance through a verification of users and devices of subcontractors. Lastly, the exposure of internal information of the domestic large company, S to North Korea wouldn’t be occurred, if foreign users were not allowed access to particular tasks and networks. The changes of IT environment are represented by Mobile, Cloud and BYOD, and all the devices of IT are being serviced via wired and wireless networks. In this situation, the security model needs to be changed, too into the Airport model which emphasizes prevention, and connection, security and integration of functions from the existing Castle model. The risk-based Airport model consists of 5A (Accounting, Authorization, Authentication, Auditing and Administration), and for applying this model, a preventive process of threatening factors should be designed. This study suggested an application method of the risk-based Airport model to the cyber security environment.