http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
배수한(Suhan Bae),윤다은(Daeun Yun),하재경(JaeKyung Ha),황보효정(Hyojeong Hwangbo),권효정(Hyojeong Gwon),장지현(Jihyun Jang),권다은(Daeun Gwon),안민규(Minkyu Ahn) 한국HCI학회 2020 한국HCI학회 학술대회 Vol.2020 No.2
파킨슨 병과 본태성 진전은 이상운동증상을 일으키는 퇴행성 신경계 질환으로 전 세계적으로 증가하고 있다. 이 두 질병에 대한 정확한 기준이 없이 임상의의 의견만으로 진단이 되어진다면 임상의 마다 상이한 진단을 내릴 수도 있다. 본 연구에서는 파킨슨병 환자가 가지고 있는 손 떨림 혹은 서행을 정량적 판단 하기위해 설계된 5 가지 기준을 제시한다. 데이터들이 일정한 속도와 시간을 가진다고 가정하고 떨림의 정도에 따라 상, 중, 하로 나눈 30 개의 데이터와 서동 데이터 10 개, 총 40 개의 데이터를 분석하여 정량화 하였다. 결과로는 떨림, 강도, 빈도에 따라 상당한 차이를 보이고 떨림 성분이 운동 성분에 영향을 미칠 수 있음을 확인하였다.
( Daeun You ),( Seung Pil Jung ),( Yisun Jeong ),( Soo Youn Bae ),( Jeong Eon Lee ),( Sangmin Kim ) 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.12
Fibronectin (FN) plays important roles in the EMT in a variety of cancer cell types. However, the mechanism by which FN expression is regulated in tamoxifen-resistant (TamR) breast cancer cells has not yet been fully elucidated. Aberrant FN expression was associated with poor prognosis in patients with luminal type A breast cancer. In addition, FN was upregulated in TamR cells. To investigate the mechanism by which FN expression is regulated, we assessed the levels of phosphorylated Akt, JNK, and STAT3 and found that they were all increased in TamR cells. Induction of FN expression was dampened by LY294002 or AKT IV in TamR cells. Furthermore, FN expression was increased by constitutively active (CA)-Akt overexpression in tamoxifen-sensitive MCF7 (TamS) cells and colony formation of TamR cells was blocked by AKT IV treatment. Taken together, these results demonstrate that FN expression is upregulated through the PI-3K/Akt pathway in tamoxifen-resistant breast cancer cells. [BMB Reports 2017; 50(12): 615-620]
Outflow Kinematics Manifested by the Hα Line: Gas Outflows in Type 2 AGNs. IV.
Kang, Daeun,Woo, Jong-Hak,Bae, Hyun-Jin American Astronomical Society 2017 The Astrophysical Journal Vol.845 No.2
<P>Energetic ionized gas outflows driven by active galactic nuclei (AGNs) have been studied as a key phenomenon related to AGN feedback. To probe the kinematics of the gas in the narrow-line region, [O III] lambda 5007 has been utilized in a number of studies showing nonvirial kinematic properties due to AGN outflows. In this paper, we statistically investigate whether the H alpha emission line is influenced by AGN-driven outflows by measuring the kinematic properties based on the H alpha line profile and comparing them with those of [O III]. Using the spatially integrated spectra of similar to 37,000 Type 2 AGNs at z < 0.3 selected from the Sloan Digital Sky Survey DR7, we find a nonlinear correlation between H alpha velocity dispersion and stellar velocity dispersion that reveals the presence of the nongravitational component, especially for AGNs with a wing component in H alpha. The large H alpha velocity dispersion and velocity shift of luminous AGNs are clear evidence of AGN outflow impacts on hydrogen gas, while relatively smaller kinematic properties compared to those of [O III] imply that the observed outflow effect on the H alpha line is weaker than the case of [O III].</P>
Wild-type p53 controls the level of fibronectin expression in breast cancer cells
You, Daeun,Jung, Seung Pil,Jeong, Yisun,Bae, Soo Youn,Kim, Sangmin NATIONAL HELLENIC RESEARCH FOUNDATION 2017 ONCOLOGY REPORTS Vol.38 No.4
<P>Aberrant fibronectin (FN) expression is associated with poor prognosis, cell adhesion, and cell motility in a variety of cancer cells. In this study, we investigated the relationship between p53 and FN expression in breast cancer cells. Basal FN expression was significantly decreased by treatment with the p53 activator III, RITA, in MCF7 breast cancer cells with wild-type p53. In addition, overexpression of wild-type p53 markedly decreased the level of FN expression in p53-mutant breast cancer cells. To examine the mechanism underlying the relationship between p53 and FN expression, we treated MCF7 breast cancer cells with the tumor promoter TPA (12-O-tetradecanoylphorbol-13-acetate). Our results showed that basal FN expression was increased by TPA treatment in a time-dependent manner. In contrast, the level of p53 expression was decreased by TPA treatment. However, the expression of FN and p53 was not altered by TPA in p53-mutant breast cancer cells. Furthermore, the alterations in FN and p53 expression in response to TPA were prevented by a specific MEK inhibitor, UO126. Finally, we demonstrated that TPA triggers degradation of p53 through the proteasomal pathway in MCF7 cells. TPA-induced FN expression was decreased by the proteasome inhibitor MG132. Under the same condition, p53 protein expression, but not mRNA expression, was reversed by MG132. Taken together, our data demonstrate that the level of FN expression is associated with the status and expression of p53 in breast cancer cells.</P>
웹쉘 기술을 통한 프록시 기반의 확장 가능한 서버 관리 프레임워크
김다은(Daeun Kim),배상욱(Sangwook Bae),김성민(Seongmin Kim),정은영(Eunyoung Jeong) 한국정보보호학회 2023 정보보호학회논문지 Vol.33 No.4
서버리스 컴퓨팅 패러다임의 등장과 함께 클라우드 기술이 발전함에 따라, 서버 관리를 위한 백엔드 인프라의 구조가 온프레미스부터 최신 컨테이너 기반 서버리스 컴퓨팅까지 다변화되고 있다. 그럼에도 불구하고, 서버 관리를 위한 접속 방식은 전통적인 SSH 프로토콜에 여전히 의존하고 있으며, 보안성 및 확장성 측면에서의 한계점으로 인해, 사용자의 서버 인프라 관리 편의성 및 업무 생산성을 저하시킨다. 이러한 문제를 해결하기 위해 본 논문에서는 웹쉘을 프록시 기반의 서버 관리 프레임워크에 적용하여 실용성과 보안성을 갖춘 서버 관리체계 설계에 활용하고자 한다. 흔히 해커들이 서버의 취약점을 이용하여 임의 명령을 실행하기 위해 웹쉘을 사용하지만, 본 논문에서는 서버 관리 측면에서의 웹쉘 기술의 활용성에 대해 고찰하고, 웹쉘 기술을 사용한 접속 프록시 기반 서버 관리 프레임워크를 새롭게 제안한다. 또한, 본 논문에서는 실제 구현을 통하여 제안한 프레임워크가 추가적인 오버헤드 없이 표준적인 서버 접속 프로토콜로 사용되어온 SSH의 단점을 보완하고, 현대의 다양화된 컴퓨팅 환경에서도 대규모의 인프라를 효율적으로 운영할 수 있음을 보인다. With the emergence of serverless computing paradigm and the innovations of cloud technology, the structure of backend server infrastructure has evolved from on-premises to container-based serverless computing. However, an access control on the server still heavily relies on the traditional SSH protocol, which poses limitations in terms of security and scalability. This hampers user convenience and productivity in managing server infrastructure. A web shell is an interface that allows easy access to servers and execution of commands from any device with a web browser. While hackers often use it to exploit vulnerabilities in servers, we pay attention to the high portability of web shell technology for server management. This study proposes a novel proxy-based server management framework utilizing web shell technology. Our evaluation demonstrates that the proposed framework addresses the drawbacks of SSH without additional overhead, and efficiently operates large-scale infrastructures in diverse computing environments.
( Daegi Kim ),( Daeun Bae ),( Kwanyong Lee ),( Ki Young Park ) 한국폐기물자원순환학회(구 한국폐기물학회) 2015 한국폐기물자원순환학회 춘계학술발표논문집 Vol.2015 No.-
The hydrothermal carbonization is one of attractive thermo-chemical method to upgrade biomass to produce biochar with benefit method from the use of no chemical catalytic. Hydrothermal carbonization improved that the upgrading and dewatering algal biomass, microalga as Chlorella vulgaris, which is conducted at temperatures ranging from 180 to 350℃ with a reaction time of 30 min. These characteristic changes in algal biomass were similar to those of coalification reactions due to dehydration and decarboxylation with increase of hydrothermal reaction temperature. The biochar became a solid fuel substance, the characteristics of which corresponded with fuel between lignite and sub-bituminous coal. The results of this study indicate that hydrothermal treatment can be used as an effective means to generate highly energy-efficient renewable fuel resources using algal biomass.
Daegi Kim,Daeun Bae,Kwanyong Lee,Ki Young Park 한국폐기물자원순환학회 2015 한국폐기물자원순환학회 학술대회 Vol.2015 No.05
The hydrothermal carbonization is one of attractive thermo-chemical method to upgrade biomass to produce biochar with benefit method from the use of no chemical catalytic. Hydrothermal carbonization improved that the upgrading and dewatering algal biomass, microalga as Chlorella vulgaris, which is conducted at temperatures ranging from 180 to 350℃ with a reaction time of 30 min. These characteristic changes in algal biomass were similar to those of coalification reactions due to dehydration and decarboxylation with increase of hydrothermal reaction temperature. The biochar became a solid fuel substance, the characteristics of which corresponded with fuel between lignite and sub-bituminous coal. The results of this study indicate that hydrothermal treatment can be used as an effective means to generate highly energy-efficient renewable fuel resources using algal biomass.