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Analysis of differential proteins in two different wing‐types of female Nilaparvata lugens
An‐Wen Liang,Ting-Ting LIU,Zi-Qiang Liang,Fang-Hai Wang 한국곤충학회 2018 Entomological Research Vol.48 No.3
Nilaparvata lugens (stal) is a rice pest and contains long‐winged and short‐winged varieties, called the wing differentiation. This study compared the protein profiles of the two wing‐types in females and two wing‐disc types 5th‐instar females by two‐dimensional electrophoresis analysis. We detected 172 and 174 protein spots in adults and 5th‐instar nymphs, respectively. The number of proteins with higher content in the long‐winged (disc) individuals is much more than that in the short‐winged (disc) individuals. A total of 32 differential protein spots were found, of which 20 were successfully identified. Their main function is about catabolic process, fiber and nucleoside binding, and they constitute 52 protein–protein interactions, which is around the glycolysis as the core. These results enrich the research on the protein Level in wing development, and provide more references for future studies.
An Emission-Aware Day-Ahead Power Scheduling System for Internet of Energy
( Chenn-jung Huang ),( Kai-wen Hu ),( An-feng Liu ),( Liang-chun Chen ),( Chih-ting Chen ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.10
As a subset of the Internet of Things, the Internet of Energy (IoE) is expected to tackle the problems faced by the current smart grid framework. Notably, the conventional day-ahead power scheduling of the smart grid should be redesigned in the IoE architecture to take into consideration the intermittence of scattered renewable generations, large amounts of power consumption data, and the uncertainty of the arrival time of electric vehicles (EVs). Accordingly, a day-ahead power scheduling system for the future IoE is proposed in this research to maximize the usage of distributed renewables and reduce carbon emission caused by the traditional power generation. Meanwhile, flexible charging mechanism of EVs is employed to provide preferred charging options for moving EVs and flatten the load profile simultaneously. The simulation results revealed that the proposed power scheduling mechanism not only achieves emission reduction and balances power load and supply effectively, but also fits each individual EV user’s preference.
Yaofa Li,Jing-Jie An,Zhi-Hong Dang,Wen-Liang Pan,Zhanlin Gao 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.1
English grain aphid, Sitobion avenae (Fabricius) (Hemiptera: Aphididae), is an important pest of wheat (Triticumaestivum L.), and is usually controlled by intensive foliar sprays of pesticides under field conditions. In order toreduce labour costs and increase the utilization of pesticides, neonicotinoids seed treatment was studied as asimple and accurate control technology for S. avenae. We evaluated the mortality of imidacloprid, acetamiprid,thiamethoxam, clothianidin, nitenpyram and dinotefuran to the English grain aphid by seed dressing methods inthe laboratory, and found that the toxicity with that LC50 of clothianidin (20.97 a.i. g/100 kg seeds) and thiamethoxam(28.84 a.i. g/100 kg seeds) to S. avenae are higher than other neonicotinoids. LC50 values of nitenpyram,imidacloprid and acetamiprid ranged between 120 a.i. g/100 kg seeds and 210 a.i. g/100 kg seeds. Dinotefuran showed the lowest toxicity with LC50 value 565.76 a.i. g/100 kg seeds to English grain aphid. Fieldplot experiments were conducted to investigate the control efficacy of neonicotinoids seed treatment for theaphid, and the effects on growth of wheat. Field observations indicated that clothianidin and thiamethoxamprovided the better control efficacy on the English grain aphid than imidacloprid, and had no influence on wheatseedling emergence. These results showed that seed treatment by neonicotinoids was effective against S. avenaethroughout the growth period, furthermore, thiamethoxam and clothianidin were the effective and safe alternativeoptions for S. avenae management in the crop.
Kuikui Jiang,Ruoxi Hong,Wen Xia,Qianyi Lu,Liang Li,Jianhao Huang,Yanxia Shi,Zhongyu Yuan,Qiufan Zheng,Xin An,Cong Xue,Jiajia Huang,Xiwen Bi,Meiting Chen,Jingmin Zhang,Fei Xu,Shusen Wang 대한암학회 2024 Cancer Research and Treatment Vol.56 No.2
Purpose This study aims to evaluate the efficacy and safety of a new combination treatment of vinorelbine and pyrotinib in human epidermal growth factor receptor 2 (HER2)–positive metastatic breast cancer (MBC) and provide higher level evidence for clinical practice. Materials and Methods This was a prospective, single-arm, phase 2 trial conducted at three institutions in China. Patients with HER2-positive MBC, who had previously been treated with trastuzumab plus a taxane or trastuzumab plus pertuzumab combined with a chemotherapeutic agent, were enrolled between March 2020 and December 2021. All patients received pyrotinib 400 mg orally once daily plus vinorelbine 25 mg/m2 intravenously or 60-80 mg/m2 orally on day 1 and day 8 of 21-day cycle. The primary endpoint was progression-free survival (PFS), and the secondary endpoints included the objective response rate (ORR), disease control rate (DCR), overall survival, and safety. Results A total of 39 patients were enrolled. All patients had been pretreated with trastuzumab and 23.1% (n=9) of them had accepted trastuzumab plus pertuzumab. The median follow-up time was 16.3 months (95% confidence interval [CI], 5.3 to 27.2), and the median PFS was 6.4 months (95% CI, 4.0 to 8.8). The ORR was 43.6% (95% CI, 27.8% to 60.4%) and the DCR was 84.6% (95% CI, 69.5% to 94.1%). The median PFS of patients with versus without prior pertuzumab treatment was 4.6 and 8.3 months (p=0.017). The most common grade 3/4 adverse events were diarrhea (28.2%), neutrophil count decreased (15.4%), white blood cell count decreased (7.7%), vomiting (5.1%), and anemia (2.6%). Conclusion Pyrotinib plus vinorelbine showed promising efficacy and tolerable toxicity as second-line treatment in patients with HER2-positive MBC.
Current Scaling and Electron Heating in a GaN/AlGaN Two-Dimensional Electron System
Kuang Yao Chen,Li-Hung Lin,Chin-An Chang,Chi-Te Liang,N. C. Chen,P. H. Chang,Wen-Jang Shiue,Zhi-Hao Sun 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.50 No.6
A GaN/AlGaN two-dimensional electron system (2DES) has been prepared on a Si substrate, and the electron heating effect in the 2DES has been studied experimentally by using the resistance of the 2DES as a self-thermometer. The relation $T_e$ $\sim$ $I^{1.42}$ was obtained, which is in contrast to $T_e$ $\sim$ $I^{0.5}$ in the spin-split resistivity peaks in a GaAs/AlGaAs 2DES. A possible reason for this is discussed