http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Ah Nul Ha (검색결과 6 건)
- 무료
- 기관 내 무료
- 유료
-
-
Lee, Ha-Nul,Kim, Young-Min,Jang, Ah-Ra,Kim, Young Ran,Park, Jong-Hwan Korean Society of Food Science and Technology 2020 한국식품과학회지 Vol.52 No.6
Recent studies have suggested that Canavalia gladiate, a dietary food and traditional folk medicine, has promising pharmaceutical potential, but the effects have mostly been demonstrated using its organo-soluble extract. To date, its immunomodulatory effect depending on the extraction method is unclear. Here, the immune responses of macrophages to C. gladiate and the underlying mechanisms were studied. C. gladiate hot water extract (CGW) induced cytokine production in bone marrow-derived macrophages (BMDMs) in a dose-dependent manner, whereas its ethanolic extract (CGE) did not. Immunoblotting analysis also showed that CGW activated nuclear factor (NF)-κB and mitogen-activated protein kinases (MAPKs). Moreover, an inhibitor assay revealed the involvement of NF-κB, p38, and JNK, but not ERK, in CGW-induced cytokine production. CGE inhibited lipopolysaccharide-stimulated production of pro-inflammatory cytokines and activation of NF-κB and MAPKs in BMDMs. The results suggest that C. gladiate regulates the immune responses of macrophages differently depending on the extraction method.
-
큰 유두함몰비를 갖는 녹내장모양시신경유두와 원발개방각녹내장안 시신경유두함몰 깊이 비교
문용석(Yong Seok Mun),하아늘(Ah nul Ha,),정진욱(Jin Wook Jeoung),박기호(Ki Ho Park),김영국(Young Kook Kim) 대한안과학회 2018 대한안과학회지 Vol.59 No.6
목적: 녹내장에서 시신경유두 표면의 함몰이 관찰된다는 것은 선행연구를 통해 알려져 있다. 큰 유두함몰비를 가진 녹내장모양시신경 유두와 원발개방각녹내장안의 시신경유두 사이에서 평균 시신경유두함몰 깊이를 정량적으로 비교하고자 하였다. 대상과 방법: 본원 녹내장 외래에 내원한 환자 중 스펙트럼영역 빛간섭단층촬영(spectral domain optical coherence tomography)인 CirrusTM HD-OCT (Carl Zeiss Meditec, Inc., Dublin, CA, USA)를 사용하여 평균 유두함몰비, 유두영역, 시신경유두함몰부피를 측정한 환자들 중, 평균 유두함몰비가 0.7 이상 0.8 이하의 녹내장모양시신경유두 환자 40명 40안과 동일 조건의 유두함몰비를 보이는 원발개방각녹내장 환자 40명 40안을 대상으로 하였다. 다음 공식을 사용하여 각 군의 평균 시신경유두함몰 깊이를 계산하였다: (시신경유두함몰부피/[유두영역×평균유두함몰비2])–200 μm. 결과: 녹내장모양시신경유두 집단의 평균 나이는 61.18 ± 11.83세, 원발개방각녹내장 집단의 평균 나이는 59.65 ± 11.69세였으며, 평균 유두함몰비는 녹내장모양시신경유두 집단 0.74 ± 0.03, 원발개방각녹내장 집단 0.75 ± 0.03으로 두 군 간 차이가 없었다 (p=0.333, t-test). 그러나 평균 시신경유두함몰 깊이는 각각 144.74 ± 82.78 μm와 199.53 ± 90.26 μm로 원발개방각녹내장군에서 유의하게 컸다(p=0.006, t-test). 결론: 녹내장모양시신경유두는 비슷한 유두함몰비를 가지는 원발개방각녹내장 환자의 시신경유두와 비교하였을 때 유의하게 얕은 평균 시신경유두함몰 깊이를 보였다. 스펙트럼영역 빛간섭단층촬영 결과지를 바탕으로 평균 시신경유두함몰 깊이를 확인하는 것은 녹내장모양시신경유두를 녹내장성 시신경유두로부터 감별하는 데 추가적인 정보를 제공할 수 있을 것으로 기대된다. Purpose: Optic nerve head surface depression in patients with glaucoma has been previously reported. We quantitatively compared the mean optic disc cup surface depth between glaucoma-like disc (GLD) patients with large cup-to-disc ratios and primary open-angle glaucoma (POAG) patients. Methods: A total of 40 eyes of 40 patients with GLD and 40 eyes of 40 patients with POAG were included in this study. All patients had an average cup-to-disc ratio of 0.7–0.8. The optic disc area, mean cup-to-disc ratio, and mean optic disc cup volume were measured using spectral domain optical coherence tomography (Cirrus™ HD-OCT; Carl Zeiss Meditec, Inc., Dublin, CA, USA). The mean optic disc cup surface depth was calculated using the formula: (mean optic disc cup volume/[optic disc area × mean cup-to-disc ratio2]) – 200 μm. Results: The mean ages of patients were 61.18 ± 11.83 and 59.65 ± 11.69 years for the GLD and POAG groups, respectively. The average cup-to-disc ratios were 0.74 ± 0.03 and 0.75 ± 0.03 for the GLD and POAG groups, respectively, but no significant difference was observed between the two groups. The mean optic disc cup surface depths were 144.74 ± 82.78 μm and 199.53 ± 90.26 μm for the GLD and POAG groups, respectively, and the difference between the two groups was statistically significant (p = 0.006, t-test). Conclusions: POAG patients showed a significantly greater mean optic disc cup surface depth compared to GLD patients with a similar mean cup-to-disc ratio. Based on the results of spectral domain optical coherence tomography, confirming the mean optic disc cup surface depth is expected to provide additional information to distinguish GLD from POAG patients.
-
백내장 수술 후 발생한 음성 이상광시증의 임상 양상과 수술 만족도에 미치는 영향
김정아,하아늘,권지원,위원량,한영근,Jeong Ah Kim,MD,Ah Nul Ha,MD,Ji Won Kwon,MD,PhD,Won Ryang Wee,MD,PhD,Young Keun Han,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.5
Purpose: To investigate the clinical characteristics of patients with pseudophakic negative dysphotopsia after cataract surgery and to analyze the risk factors of pseudophakic negative dysphotopsia as well as the postoperative effects on patient's satisfaction. Methods: This study included 1,020 eyes of 690 patients who underwent phacoemulsification and posterior chamber lens insertion between January 2010 and March 2012. Retrospective chart review was conducted to evaluate the prevalence of negative dysphotopsia according to the site of clear corneal incision during cataract surgery and the type of implanted intraocular lens (IOL). The clinical outcome of Neodymium:yttrium-aluminium-garnet (Nd:YAG) laser anterior capsulotomy in negative dysphotopsia patients was evaluated. Using a telephone survey, patients were asked to subjectively answer 18 questions regarding satisfaction after cataract surgery, the severity of visual symptoms and the effect of negative dysphotopsia in their daily life. Results: Negative dysphotopsia developed in patients who underwent uneventful cataract surgery and successful implantation of IOL in the bag. The patients' vision was corrected up to 20/20 (0.00 log MAR) and HVF P60-4 showed no abnormality in their visual field. There were significantly more patients with the SN60WF IOL who reported negative dysphotopsia but no other factors associated with the prevalence of negative dysphotopsia. During the telephone survey, patients complained of difficulties in their daily life related to the negative dysphotopsia symptoms and reported decreased satisfaction after cataract surgery. Conclusions: Although negative dysphotopsia can decrease the patient's satisfaction after cataract surgery, the genesis of negative dysphotopsia and an objective method to test for negative dysphotopsia is necessary. Therefore, a prospective large study should be conducted to evaluate the cause and treatment of negative dysphotopsia. J Korean Ophthalmol Soc 2014;55(5):669-678
-
-
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
