Anti-tumor Promoting Activity of Some Malaysian Traditional Vegetables (Ulam)

L. Yang Mooi,A. M. Ali,A. B. Norhanom,K. Mat Salleh,A. Murakami,K. Koshimizu 한국생약학회 1999 Natural Product Sciences Vol.5 No.1

Ethanolic extracts of different parts of 10 loyal traditional vegetables (ulam) (Amarunthus gangeticus, Jussiaea linifolia, Eugenic polyantha, Trapa incisca, Trichosanthes anquina, Mangifera indica, Pachyrrhirus erosus, Barringtonia mcarostachya, Carica papaya, and Coleus tuberosus) were screened for in vitro anti-tumor promoting activity using the inhibition test of Epstein-Barr virus (EBV) activation in Raji cells induced by phorbol 12-myristate 13-acetate and sodium-n-butyrate. All the extracts were found to have strong inhibition activity toward EBV-activation, except for leaf extract of T. anquina. The extracts were non-cytotoxic to the Raji cells except for the extracts of A. gangeticus (leaves), B. mucrostachya (leaves), E. polyuntha (young leaves), and J. linifolia (leaves) where the viability of the cells were decreased significantly.

A New Field Sequential Stereoscopic LCDs by use of Dual-Directional-Backlight

Yuuki, A.,Agari, M.,Iwsaki, N.,Sasagawa, T.,Tahata, S.,Satake, T.,Murakami, O.,Oda, K.,Ito, A.,Miyake, S. The Korean Infomation Display Society 2004 Journal of information display Vol.5 No.2

We have developed the Scan-backlight Stereoscopic LCD that is a kind of field-sequential -Stereoscopic LCD combining the Dual- Directional- Backlight and the fast-response OCB panel. The Dual-Directional-Backlight using a double-sided prism sheet can change the direction of light by switching the LED light sources. The OCB panel using Feed-Forward Drive can realize frame rate of 120 Hz. As a result, the Scan-backlight Stereoscopic display works at its original resolving power, and produces flicker-free stereoscopic images. This auto- stereoscopic display can resolved the problems of the double images and the pseudoscopic images in case of watching at oblique angles.

Comparison of various k-ε models and DSM applied to flow around a high-rise building - report on AIJ cooperative project for CFD prediction of wind environment -

Mochida, A.,Tominaga, Y.,Murakami, S.,Yoshie, R.,Ishihara, T.,Ooka, R. Techno-Press 2002 Wind and Structures, An International Journal (WAS Vol.5 No.2

Recently, the prediction of wind environment around a building using Computational Fluid Dynamics (CFD) technique comes to be carried out at the practical design stage. However, there have been very few studies which examined the accuracy of CFD prediction of flow around a high-rise building including the velocity distribution at pedestrian level. The working group for CFD prediction of wind environment around building, which consists of researchers from several universities and private companies, was organized in the Architectural Institute of Japan (AIJ) considering such a background. At the first stage of the project, the working group planned to carry out the cross comparison of CFD results of flow around a high rise building by various numerical methods, in order to clarify the major factors which affect prediction accuracy. This paper presents the results of this comparison.

Immune Responses in Broiler Chicks Fed Propolis Extraction Residue-supplemented Diets

C. Eyng,A. E. Murakami,T.C. Santos,T.G.V. Silveira,R.B. Pedroso,D.A.L. Lourenco 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.1

This study was conducted to evaluate the effect of inclusion of propolis extraction residue in the feed of broilers from 1 to 21 d of age on phagocytic activity of macrophages, cutaneous basophil hypersensitivity response to phytohemagglutinin, antibody production against Newcastle disease, lymphoid organ weight and hematological profile and to determine the optimal level of inclusion. 120 chicks, reared in metabolism cages until 21 days of age, were distributed in a completely randomized design, with five treatments (0%, 1%, 2%, 3%, and 4% of propolis residue) and six replications. The relative weight of thymus and monocyte percentage were affected by propolis residue, with a quadratic response (p<0.05) and lowest values estimated at 2.38% and 2.49%, respectively. Changes in relative weight of cloacal bursa and spleen, percentage of lymphocyte, heterophil, basophil, eosinophil, and heterophil:lymphocyte ratio, antibody production against Newcastle disease, phagocytic activity of macrophages and the average number of phagocytosed erythrocytes were not observed. The nitric oxide production with regard to positive control (macrophages+erythrocytes) decreased linearly (p<0.05) with increased doses of propolis residue. The remaining variables of nitric oxide production (negative control – macrophages, and difference between the controls) were not affected by propolis residue. The cutaneous basophil hypersensitivity response to phytohemagglutinin as determined by the increase in interdigital skin thickness exhibited a quadratic response (p<0.05), which predicted a lower reaction response at a dose of 2.60% of propolis residue and highest reaction response after 43.05 hours of phytohemagglutinin injection. The inclusion of 1% to 4% of propolis extraction residue in broiler diets from 1 to 21 days of age was not able to improve the immune parameters, despite the modest changes in the relative weight in thymus, blood monocyte percentage, nitric oxide concentration, and interdigital reaction to phytohemagglutinin.

Immune Responses in Broiler Chicks Fed Propolis Extraction Residue-supplemented Diets

Eyng, C.,Murakami, A.E.,Santos, T.C.,Silveira, T.G.V.,Pedroso, R.B.,Lourenco, D.A.L. Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.1

This study was conducted to evaluate the effect of inclusion of propolis extraction residue in the feed of broilers from 1 to 21 d of age on phagocytic activity of macrophages, cutaneous basophil hypersensitivity response to phytohemagglutinin, antibody production against Newcastle disease, lymphoid organ weight and hematological profile and to determine the optimal level of inclusion. 120 chicks, reared in metabolism cages until 21 days of age, were distributed in a completely randomized design, with five treatments (0%, 1%, 2%, 3%, and 4% of propolis residue) and six replications. The relative weight of thymus and monocyte percentage were affected by propolis residue, with a quadratic response (p<0.05) and lowest values estimated at 2.38% and 2.49%, respectively. Changes in relative weight of cloacal bursa and spleen, percentage of lymphocyte, heterophil, basophil, eosinophil, and heterophil:lymphocyte ratio, antibody production against Newcastle disease, phagocytic activity of macrophages and the average number of phagocytosed erythrocytes were not observed. The nitric oxide production with regard to positive control (macrophages+erythrocytes) decreased linearly (p<0.05) with increased doses of propolis residue. The remaining variables of nitric oxide production (negative control - macrophages, and difference between the controls) were not affected by propolis residue. The cutaneous basophil hypersensitivity response to phytohemagglutinin as determined by the increase in interdigital skin thickness exhibited a quadratic response (p<0.05), which predicted a lower reaction response at a dose of 2.60% of propolis residue and highest reaction response after 43.05 hours of phytohemagglutinin injection. The inclusion of 1% to 4% of propolis extraction residue in broiler diets from 1 to 21 days of age was not able to improve the immune parameters, despite the modest changes in the relative weight in thymus, blood monocyte percentage, nitric oxide concentration, and interdigital reaction to phytohemagglutinin.

Generation of inflow turbulent boundary layer for LES computation

Kondo, K.,Tsuchiya, M.,Mochida, A.,Murakami, S. Techno-Press 2002 Wind and Structures, An International Journal (WAS Vol.5 No.2

When predicting unsteady flow and pressure fields around a structure in a turbulent boundary layer by Large Eddy Simulation (LES), velocity fluctuations of turbulence (inflow turbulence), which reproduce statistical characteristics of the turbulent boundary layer, must be given at the inflow boundary. However, research has just started on development of a method for generating inflow turbulence that satisfies the prescribed turbulence statistics, and many issues still remain to be resolved. In our previous study, we proposed a method for generating inflow turbulence and confirmed its applicability by LES of an isotropic turbulence. In this study, the generation method was applied to a turbulent boundary layer developed over a flat plate, and the reproducibility of turbulence statistics predicted by LES computation was examined. Statistical characteristics of a turbulent boundary layer developed over a flat plate were investigated by a wind tunnel test for modeling the cross-spectral density matrix for use as targets of inflow turbulence generation for LES computation. Furthermore, we investigated how the degree of correspondence of the cross-spectral density matrix of the generated inflow turbulence with the target cross-spectral density matrix estimated by the wind tunnel test influenced the LES results for the turbulent boundary layer. The results of this study confirmed that the reproduction of cross-spectra of the normal components of the inflow turbulence generation is very important in reproducing power spectra, spatial correlation and turbulence statistics of wind velocity in LES.

Effects of Functional Oils on Coccidiosis and Apparent Metabolizable Energy in Broiler Chickens

Murakami, A.E.,Eyng, C.,Torrent, J. Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.7

The objective of the present study was to investigate the effects of a mixture of functional oils (Essential, Oligo Basics Agroind. Ltda) on performance response of chickens challenged with coccidiosis and the determination of apparent metabolizable energy (AME), nitrogen-corrected apparent metabolizable energy (AMEn), the coefficients of protein and ether extract digestibility and intestinal morphology of broilers fed with diets containing Essential. In Exp. 1, a completely randomized design (CRD) was used, with one control diet without Essential inclusion with coccidiosis (Eimeria acervulina, Eimeria maxima, and Eimeria tenella) challenged birds and two different inclusion rates of Essential (1.5 kg/ton and 2 kg/ton) with coccidiosis-challenged and non-challenged birds for each inclusion rate, using 10 replicates and 50 birds per experimental unit. After 7 d of coccidiosis challenge, the livability was approximately 10% lower (p<0.05) for the control group. Intestinal lesion scores were lower (p<0.05) in the anterior intestine and the cecum for the chickens supplemented. Feed efficiency and growth rate were improved in birds supplemented with Essential (p<0.05) before the coccidiosis challenge and during the first 7 d post infection. In Exp. 2, a CRD was used, with one control diet without Essential inclusion and one diet with inclusion of Essential (1.5 kg/ton), using nine replications and 33 chicks per pen. The diets with Essential yielded approximately 4% higher AME (p = 0.003) and $AME_n$ (p = 0.001). Essential supplementation increased villus height in the jejunum on d 14 (p<0.05). Villus height:crypt depth ratio for the supplemented birds was larger (p<0.05) in the jejunum on d 7, larger (p<0.05) in the jejunum and ileum on d 14. In conclusion, these functional oils improved the energy utilization and the livability and decreased lesions caused by coccidiosis in supplemented birds.

Development of a Laser-Guided Deep-Hole Evaluating Probe

A. Katsuki,H. Onikura,T. Sajima,A. Mohri,Y.Yuge,H. Murakami,T. Katayama 제어로봇시스템학회 2001 제어로봇시스템학회 국제학술대회 논문집 Vol.2001 No.10

SπRIT: A time-projection chamber for symmetry-energy studies

Shane, R.,McIntosh, A.B.,Isobe, T.,Lynch, W.G.,Baba, H.,Barney, J.,Chajecki, Z.,Chartier, M.,Estee, J.,Famiano, M.,Hong, B.,Ieki, K.,Jhang, G.,Lemmon, R.,Lu, F.,Murakami, T.,Nakatsuka, N.,Nishimura, M Elsevier 2015 Nuclear Instruments & Methods in Physics Research. Vol.784 No.-

<P><B>Abstract</B></P> <P>A time-projection chamber (TPC) called the SAMURAI Pion-Reconstruction and Ion-Tracker (SπRIT) has recently been constructed at Michigan State University as part of an international effort to constrain the symmetry-energy term in the nuclear Equation of State (EoS). The SπRIT TPC will be used in conjunction with the SAMURAI spectrometer at the Radioactive Isotope Beam Factory (RIBF) at RIKEN to measure yield ratios for pions and other light isospin multiplets produced in central collisions of neutron-rich heavy ions, such as <SUP>132</SUP>Sn+<SUP>124</SUP>Sn. The SπRIT TPC can function both as a TPC detector and as an active target. It has a vertical drift length of 50cm, parallel to the magnetic field. Gas multiplication is achieved through the use of a multi-wire anode plane. Image charges, produced in the 12096 pads, are read out with the recently developed Generic Electronics for TPCs.</P>

THE PROPERTIES OF DUST EMISSION IN THE GALACTIC CENTER REGION REVEALED BY FIS-FTS OBSERVATIONS

Yasuda, A.,Kaneda, H.,Takahashi, A.,Nakagawa, T.,Kawada, M.,Okada, Y.,Takahashi, H.,Murakami, N. The Korean Astronomical Society 2012 天文學論叢 Vol.27 No.4

We present the results of far-infrared spectral mapping of the Galactic center region with FIS-FTS, which covered the two massive star-forming clusters, Arches and Quintuplet. We find that two dust components with temperatures of about 20 K and 50 K are required to fit the overall continuum spectra. The warm dust emission is spatially correlated with the [OIII] $88{\mu}m$ emission and both are likely to be associated with the two clusters, while the cool dust emission is more widely distributed without any clear spatial correlation with the clusters. We find differences in the properties of the ISM around the two clusters, suggesting that the star-forming activity of the Arches cluster is at an earlier stage than that of the Quintuplet cluster.