운동이 혈장 , 간장 , 뇌 , 신장 및 골격근의 지질치에 미치는 영향

현송자(Hyun Song Ja) 한국여성체육학회 1994 한국여성체육학회지 Vol.8 No.-

最近, 많은 硏究者들에 의하여 血淸脂質, 特히 血淸 콜레스테롤과 血淸 中性脂肪의 增加는 動脈硬化 및 心筋梗塞의 成人病과 密接한 關係가 있다고 하였다. 본 硏究는 運動 트레이닝의 프로그램이 血漿, 肝臟, 腦, 腎臟 및 骨格筋의 脂質値에 어떠한 影響을 주는가를 檢討하는데 그 目的이 있다. 4週된 wistar系의 숫놈의 쥐를 사용하여, 對照群과 運動群으로 나누었다. 運動群은 하루 30분간 遊泳運動을 시켰고 對照群은 運動을 시키지 않고 3週間 調査한 結果, 體重, 肝臟, 心臟, 腎臟은 運動群이 有意하게 무거웠으나, 腦와 骨格筋은 變化가 없었다. 運動이 血漿의 TG 및 T-CH는 有意하게 減少시켰고 또 HDL-C는 有意하게 上昇시켰다. 肝臟에 있어서도 TG 및 T-CH가 有意하게 減少시켰으나, 腦, 腎臟, 骨格筋도 運動에 의하여 減少되었으나 兩群間에는 有意差가 없었다.以上의 結果를 볼 때, 運動 트레이닝이 血漿, 肝臟, 腦, 腎臟 및 骨格筋의 脂質値를 減少시키어 動脈硬化 및 心臟梗塞의 成人病을 豫防한다고 思料된다.

운동이 심근 및 골격근의 마이오그로빈 농도에 미치는 영향

현송자(Hyun Song Ja) 한국여성체육학회 1992 한국여성체육학회지 Vol.6 No.-

最近, 많은 硏究者들에 依해 미토콘드리아와 마이오그로빈은 特殊性 運動이나 트레이닝의 生化學的 指標로 利用하고 있다. 본 硏究는 운동 트레이닝의 프로그램이 즉 1週, 3週, 6週에 心筋 및 骨格筋의 마이오그로빈 농도에 어떠한 影響을 주는가를 檢討하는데 그 目的이 있다. 4週된 Wistar系의 숫놈의 쥐를 사용하여, 對照群과 運動群으로 나누었다. 運動群은 하루에 90분간 遊泳運動을 시켰고, 대조군은 운동을 시키지 않고 6週間 調査한 結果, 心筋과 骨格筋의 重量은 對照群보다 무거웠다. 特히 3週, 6週의 運動에 있어 心筋이 對照群보다 유의한 (p<0.05) 差를 나타냈다. 6週의 骨格筋은 對照群보다 有意하게(p<0.001) 무거웠다. 마이오그로빈의 농도는 心筋 및 骨格筋 모두 運動에 의해 上昇하였고, 골격근의 가재미근은 6주에, 비복근은 3, 6주에 대조근에 비해 유의하게 (p<0.01, p<0.05) 상승하였다.以上의 結果에서 볼 때, 운동 트레이닝이 心筋 및 骨格筋의 마이오그로빈 농도를 上昇시킨다고 생각된다.

운동(運動)이 골격근(骨格筋)의 미토콘드리아 수와 미토콘드리아 DNA량에 미치는 영향(影向)

현송자(Song Ja Hyun) 한국여성체육학회 1993 한국여성체육학회지 Vol.7 No.-

유산소운동이 혈장 유리칼슘 농도 조절에 미치는 영향

현송자 ( Song Ja Hyun ),석혜경 ( Hae Kyoung Seok ) 한국스포츠정책과학원(구 한국스포츠개발원) 2006 체육과학연구 Vol.17 No.2

본 연구는 30분간 60%HRmax 유산소 운동이 혈장 유리칼슘 농도 조절에 부갑상선 호르몬 혹은 pH인자 중 어떤 인자가 영향을 주는가를 알아보는데 목적이 있다. 연구 대상은 건강한 남자대학생 14명을 운동군, 대조군 각각 7명씩 무작위로 나누었고 운동군은 60%HRmax 유산소 달리기 운동을 30분간 주3회 8주간을 실시하였다. 두 군 모두 60%HRmax 일회성 유산소 달리기 운동 30분을 실시하여 운동전, 운동직후, 회복기 5분, 10분, 30분에 전완에서 10ml 혈액을 채혈하였으며 이온화 칼슘과 pH는 전해질 분석기로, 총칼슘은 자동생화학분석기로, 알부민은 생화학분석기로 분석하였다. 부갑상선호르몬은 감마 카운터로, 혈장 젖산과 암모니아의 측정은 생화학분석기로, 케톤체 측정은 Mass Selective detector로 분석하여 비교 검토한 결과는 다음과 같다. 혈장 알부민농도는 운동전에 비해 운동 직후 운동군, 대조군 모두 유의하게 증가(p<.001)하였고, 혈장 총칼슘은 두 군 모두 유의하게 증가(p<.001)하였으나, 혈장 이온화칼슘농도는 두 군 모두 유의하게 감소(p<.001)하였다. 대사산물인 혈장 젖산(p<.001)과 암모니아(p<.001)가 유의하게 증가되어 pH농도가 유의하게 저하(p<.001)되었다. 한편 부갑상선 호르몬은 두 군 모두 유의하게 증가(p<.001)하였다. 회복기에서 유리칼슘과 케톤체 농도는 5분에, 젖산은 30분에 회복되었으나 다른 변인들은 30분이 되어도 회복되지 못하였다. 이상의 결과에서 일회성 유산소 운동은 트레이닝을 한 사람이나 안 한 사람이나 혈장 유리 이온화 칼슘 농도의 조절은 부갑상선 호르몬과 pH인자 모두가 영향을 주는 것으로 시사되었다. The aim of the present study was to examine how the concentration of blood ionized calcium(Ca++) would change due to pH or parathyroid hormone as a single bout of aerobic exercise. The divided into two groups ; the one is exercise group(n=7), the other is control group(n=7). The exercise group was taken for 30min 60%HRmax aerobic exercise training three times in a week for eight weeks. All subjects were taken 30minute of 60%HRmax on treadmill running, Blood sampling was done pre, post and recovery (5,10 or 30min) from subjects. The plasma albumin concentrations in the both groups were significantly(p<0.001) increased immediately post-exercise compared to pre-exercise. The plasma total Ca concentrations were significantly(p<0.001) increased, while the ionized Ca++ concentrations in the all subjects were significantly(p<0.001) decreased immediately post-exercise compared to the pre-exercise. The lactate(p<0.001) and NH3 (p<0.001) concentrations were significantly in creased, because the pH was significantly(p<0.001) dropped. The plasma PTH concentration was significantly(p<0.001) increased in the exercise group than in the control group. It suggest that the pH and PTH concentration altogether gave to effect the regulation of ionized calcium concentration in a single bout of the aerobic exercise. Further study is needed to clarify the physiological implications of a intensity due to exercise and also it mechanism.

고강도운동이 산화적 DNA 손상의 지표로서 림프구 및 뇨의 8-OHdG 농도에 미치는 영향

현송자 ( Song Ja Hyun ),김귀백 ( Kwi Baek Kim ) 한국운동영양학회 2004 Physical Activity and Nutrition (Phys Act Nutr) Vol.8 No.3

Effect of high intensive exercise on 8-hydroxy-2`-deoxyguanosine as a marker of oxidative DNA damage was evaluated in untrained volunteers. Fourteen male university students were randomly divided into two groups (maximal group n = 7. 80% HR group n = 7). The maximal group were performed a treadmill running at maximal until exhaustion and 80% HRmax for 30 min. who were performed a treadmill running at maximal and 80% HRmax for 30 min. The subjects had their peripheral blood and urine taken before and immediately after exercise. Plasma concentration of creatinine and purine metabolites increased significantly (p<.05) after 80% HRmax or maximal exercise. The urinary molar ratio of hypoxanthine to creatinine increased significantly. while those of xanthine and uric acid decreased significantly after intensive exercise. The 8-OHdG in lymphocytes increased, but 8-OHdG to creatinine ratio in urine decreased after maximal and 80% HRmax exercise. These results suggest that 80% HRmax exercise may induce higher oxidative DNA damages than maximal exercise.

Disciplinary Session 8 / Sport Physiology / Physiological Effects of Ergogenic Aids : 올림픽코스 트라이애슬론 경기전 L-Glutamine 투여가 혈장암모니아와 글루타민 농도에 미치는 영향

나재철,현송자,박찬호 ( Jae Chul Na,Song Ja Hyun,Chan Ho Park ) 한국체육학회 1998 국제스포츠과학 학술대회 Vol.1998 No.2

학술발표 : 초청강연 : 유산소성운동이 혈장 글루타민 농도에 미치는 영향

나재철(Na Jae Chul),현송자(Hyun Song Ja),이상우(Lee Sang Woo) 한국운동영양학회 1997 한국운동영양학회 학술발표논문집 Vol.- No.3

트라이애슬러의 비타민Q 섭취가 호흡순환기능 및 항산화 효소활성에 미치는 영향

현송자,김귀백,박상일,석혜경 東亞大學校附設스포츠科學硏究所 2002 스포츠科學硏究論文集 Vol.20 No.-

The purpose of this present study was to investigate the effect of VitaminQ supplementation on antioxidant enzyme activities and cardiorespiratory function following prolonged exercise in trained triathlers. Male 14 healthy college students of trained triathlers participated in exercise sessions. The subjects were divided into 2 groups, as Non-supplement(NS) or VitaminQ supplement(VQ) groups. VitaminQ subjects were participated in two exercise sessions: an initial prolonged exercise(swim 750m, running 10㎞) and 70%V O2max treadmill running exercise. The Non-supplement group fed normal diet. VitaminQ group adminstated 90㎎/day for 4weeks. Venous blood samples were drown from the forearm antecubital vein pre-supplement, pre-exercise and immediately post-exercise. The results of this study can be summarized as follow: First, the SOD activity of RBC was not changed, while the GPx, GR or GR/GPx activies of Hb were significantly increased following prolonged exercise with CoQ10 supplementation. Second, 70%VO2max treadmill running exercise increased significantly the V O2max and VE, but the heart rate significantly decreased. In conclusion, the present results clearly show that the VitaminQ supplementation gave rise to increase the GPx or GR activies and to improve the cardiorespiratory function.

8주간 유산소운동이 혈중전해질 농도와 혈중pH에 미치는 영향

현송자,석혜경,김귀백 東亞大學校附設스포츠科學硏究所 2001 스포츠科學硏究論文集 Vol.19 No.-

The purpose of this study is to analyze the electrolyte such as blood ph, Na^(+), K^(+), Ca^(2+), Mg^(2+), etc on the each stage of pre-exercise, post-exercise, each 5 minute-recovery, 10 minute-recovery & 30 minute- recovery after exercise. For this experiment, 14 male students at the department of athletics in B Information Technology college in Busan was classified into each 7 exercise group and 7 non-exercise group, and after training them on the intensity of 60%HRmax of each subject 3 period a week for 8 consecutive weeks, the experiment was carried out with the same condition as training manner in treadmill. The results of this study are as follows. 1. Change of Blood Ph Through Aerobic Exercise In exercise group and non-exercise group, there was no particular change in Blood Ph between rest before training & the rest after 8 week- training according to t test. In case of exercise group, after 8 week-training blood ph value was significantly decreased, and at the 30minute-recovery after exercise, ph value was recovered to the degree of rest (p<.001). In case of non-exercise group, blood ph indicated significant change as the similar tendency showed in exercise group, at 10 minute-recovery after exercise, blood ph was recovered to the degree of rest. (p<.001). The change of ph by period between exercise group and non-exercise group was not significantly different. 2. Change of Blood Electrolyte Through Aerobic Exercise 1) Change of blood Na+ through aerobic exercise In exercise group and non-exercise group, the change of Na^(+) between the rest before training and the rest after training was not significantly different according to the result of t test. In case of exercise group, after performing 8 week-training, Na^(+) value was significantly increased, and at 10 minute-recovery after exercise, Na^(+) value began to recover into the value in rest, and after 30 minute-recovery after exercise, Na^(+) value was recovered into the degree of rest (p<.05). In case of the change of Na^(+) in non exercise group, after exercise, Na' value was significantly increased in comparison with rest period, and at 5 minutes after exercise, it was recovered into the degree of rest. (p<.01). The change of Na^(+) by period between exercise group and non-exercise group was not significantly different. 2) Change of Blood K^(+) through aerobic exercise In exercise group and non-exercise group, the change of K^(+) in rest before training and the rest after training was indicated that there was no significant difference according to t test. In case of exercise group, after 8 week training, K^(+) value was significantly increased, and at 5 minute-recovery after exercise, K^(+) value was recovered into the value in rest (p<.05). K^(+) in non-exercise group was not significantly changed. 3) Change of blood Ca^(+) through aerobic exercise In case of exercise group, the change of Ca^(+) in rest before training and the rest after training was not significantly different according to the result of t test. In case of non-exercise group, the change of Ca^(+) in rest before training and the rest after training was significantly different according to the result of t test (p<.05). In case of exercise group, after 8 week-training, Ca^(+) value was significantly increased, and at 5 minute- ecovery after exercise, Ca^(+) value began to recover into the degree of rest, and after 30 minute-recovery after exercise, Ca^(+) value was recovered to the degree of rest (p<.01). In case of the change of Ca^(+) in non-exercise group, after training, Ca^(+) value was significantly increased in comparison with rest period, and at 30 minute-recovery after exercise, Ca^(+) value was recovered into the degree of rest. (p<.001). In case of the change of Ca^(+) by period between exercise group and non-exercise group, after exercise and at 5 minutes recovery after exercise, the change of Ca^(+) in non-exercise group is higher than that of exercise group (p<.01). 4) Change of blood Mgt^(2+) through aerobic exercise In exercise group and non-exercise group, the change of Mg^(2+) between rest before training and the rest after training was not significantly different according to the result of t test. In both cases of exercise group and non-exercise group, after 8 week- raining, the change of Mg^(2+) was not significantly different. The change of Mg^(2+) by period between exercise group and non-exercise group, after exercise, the change of Mg^(2+) of non-exercise group was higher than that of exercise group (p<.01). 3. Correlation Between Blood Ph and Electolyte Through Aerobic Exercise In performance of 8 week aerobic training, the result of correlation analysis between blood ph and electrolyte in pre-exercise, post-exercise, each 5 minute, 10 minutes, 30 minutes-recovery after exercise showed that in case of Na^(+), K^(+), Mg^(2+) did not have significant correlation, but in case of Ca^(2+), it showed significant negative correlation in pre-exercise and at 10 minute- recovery after exercise. (p<.05).

야구선수 골격근의 미토콘드리아 유산소효소 활성에 관한 연구

현송자,고기채,윤영학,홍성찬,김원천,이재식 대한스포츠의학회 1993 대한스포츠의학회지 Vol.11 No.1

The present study examined mitochnrial enzyme activities of skeletal muscle(citrate synthase, cytochrome oxidase, cytochrome, NADH dehydrogenase) Subjects were six male baseball phayers. We obtained muscle samples with a needle biopsy technique. The citrate synthase activities were measured by spectrophotometric DTNA assay. The cytochrome oxidase activities were measured by Aschenbrenner method with spectrophotometric assay. The results obtained in the present study were as follows ; 1. In citrate synthase activities, K.K, KH, SW were 0.209U/mg, 0.180U/mg, 0.088U/mg respectively. 2. In cytochrome oxidase activities, SW was 0.25U/mg, KH was 0.19U/mg, KK was 0.17U/mg. 3. In NADH dehydrogenase activities, SW, KH, KK were 0.43U/mg, 0.28U/mg, 0.37U/mg respectively.