감각신경성 청력손실에 영향을 미치는 제 요인에 관한 연구

홍성철,배성욱,이종영,Hong, Seong-Chul,Bae, Seong-Wook,Lee, Jong-Young 대한예방의학회 1998 예방의학회지 Vol.31 No.2

감각신경성 난청은 성인에서 장애의 원인 중 큰 비중을 차지하고 있으며, 특히 소음성 난청은 흔한 직업병 중의 하나이며 산업보건사업의 주요 관심 중의 하나이다. 그러나 소음폭로와 노화를 제외하고는 대부분의 경우 그 원인이 규명되지 않고 있는 실정이다. 그러므로 난청에 대한 개인간의 감수성을 결정하는데 중요한 요인을 찾는 것은 중요하며 최근 청력손실의 측정치로서 소음 외 변수와의 상관성을 연구함으로써 청력손실에 대한 개인의 감수성의 차이를 밝히려는 많은 시도가 있었다. 특히 소음성 난청에 대한 많은 연구가 있어 왔지만 소음성 난청에 대한 감수성의 개인차에 대해서는 만족하게 설명하지 못하고 있다. 본 연구는 소음 비폭로자를 대상으로 소음폭로 이외 감각신경성 난청을 유발하는 잠재적 위험 인자들을 찾아내어 그 위험인자들의 역할을 평가하기 위해 주로 심혈관 위험인자와 지혈 및 혈액점도 요인이 청력손실에 미치는 영향에 대해 조사하였다. 대구시내 모 대학병원에서 91년에서 96년까지 종합검진을 받은 3050명을 대상으로 하여 청력검사와 혈액검사 및 생화학 검사 결과를 검진자료에 추출하여 위험인자들과 청력손실간의 관련성을 연구하였다. 그 결과 소음을 제외하고 감각신경성 청력손실에 미치는 영향으로 연령과 성별이 가장 크며, 성별 분포의 차이는 연구 변수에는 포함되지 않는 흡연력, 취미, 과거 소음폭로 등이 영향을 미친 것으로 보이며 본 연구에서는 확인할 수 없었다. 그리고 심혈관 위험인자인 체격지수, 혈압, 총콜레스테롤, 중성지방이 양의 영향을 알부민은 음의 영향을 어느 정도 미치는 것으로 보인다. 혈중점도 및 지혈인자와 관련하여 헤마토크릿, 백혈구, 혈소판 용적백분율, 적혈구침강속도가 어느 정도 양의 관련성이 있는 것으로 나타났다. 그리고 심혈관 위험인자와 혈액점도 및 지혈인자는 상호 관련성이 있으며, 이들과 소음노출 등이 서로 상호 작용하여 청력에 나쁜 영향을 미치는 것으로 보인다. Reports on a potential relationship between sensory neural hearing loss(SNHL) and cardiovascular or hematologic factor show that the results are controversial. A detailed analysis of risk factors in the development of SNHL was carried out in 3,050 non-noise exposed healthy worker. The mean hearing threshold of both ears at 500, 1000, 2000, 4000, 8000Hz was measured and the effect of age, possible cardiovascular risk factor and hematologic factor (blood viscosity and hemostatic factors) on SNHL were evaluated. first, each of these were associated with loss of hearing sensitivity when univariately and multivariatively analysed. In a multiple regression model, age, sex, body mass index, WBC and total cholesterol level were independently associated with the mean of hearing sensitivity decrease at 4000 and 8000Hz. Second, study subjects were divided into two group (normal vs SNHL) and we compare the possible risk between both groups, and analysed univariate and multivariative logistic model. In a multiple logistic regression model, age, sex, body mass index, WBC and total cholesterol level, total protein, platelet were independently associated with SNHL. Our results show that we have some reliable indices of susceptibility to SNHL using cardiovascular measures or biochemical factor, but future, more extensive studies are required.

조절 라디칼 중합법에 의한 폴리올레핀 기반 분절 공중합체의 제조

홍성철 ( Sung Chul Hong ),이성훈 ( Seong Hoon Lee ),조현철 ( Hyun Chul Cho ) 한국고무학회 2009 엘라스토머 및 콤포지트 Vol.44 No.3

폴리올레핀은 뛰어난 물성과 낮은 가격으로 인하여 가장 큰 시장을 가진 범용 고분자이다. 그러나, 폴리올레핀은 대표적인 비극성 고분자로, 다른 물질과의 상호 작용이 중요한 상용화제, 개질제, 접착제 등의 용도로는 그 사용이 제한될 수 밖에 없다. 따라서, 보다 극성을 가진 고분자 사슬을 폴리올레핀에 블록 또는 그라프트 공중합체의 형태로 도입함으로써 기능성 폴리올레핀 하이브리드를 제조하려는 노력이 계속되어 왔다. 특히, 잘 제어된 구조와 조성을 가진 공중합체를 제조하기 위하여 리빙라디칼 중합법이 사용될 수 있으며, 그 중 조절라디칼 중합법은 중합을 잘 제어할 수 있다는 장점 이외에 다양한 단량체종과 중합 공정에 적용될 수 있다는 점에서 많은 주목을 받고 있다. 이에 따라, 본 리뷰 논문에서는 조절라디칼 중합법을 이용한 폴리올레핀 기반 블록 또는 그라프트 공중합체의 제조에 대하여 정리해 보았다. 폴리이소부틸렌, 폴리에틸렌, 폴리프로필렌 등의 비극성 범용고분자들과 폴리아크릴레이트, 폴리메타아크릴레이트, 폴리스티렌 등의 극성 고분자들과의 하이브리드를 통한 기능성 폴리올레핀의 제조에 대하여 정리하였다. Polyolefins are important commodity polymers with the largest volume of business owing to their outstanding combination of cost performance and excellent physical properties. However, the lack of functional groups often has limited their end uses, such as compatibilizer, modifier and adhesive, where the interaction with other materials is especially important. The incorporation of functional groups as polymer segments to afford block or graft polyolefin copolymers has been extensively investigated in the context of the functional polyolefin hybrids. Living polymerization processes have been considered to be an efficient method to prepare the polyolefin hybrids with precisely controlled architecture and compositions. Among the living polymerization techniques, controlled/living radical polymerization (CRP) methods are very effective not only because of the controllability of polymerization but also because of the versatility of monomers and polymerization conditions. In this review paper, progresses on the preparations of polyolefin graft or block copolymers through CRP techniques are summarized. The commodity polymers such as polyisobutylene, polyethylene and polypropylene are combined with polar segments such as polyacrylate, polymethacrylate, polystyrene to yield functionalized polyolefins.

제주도 노인들의 치매유병률과 관련요인

홍성철(Seong-chul Hong),이창인(Chang-In Lee),고금자(Keum-ja Ko),강문정(Moon-jung Kang),현인숙(In-sook Hyun),정민(Min Jung),주민선(Min-sun Chu),채수경(Soo-gyung Chae),이혜숙(Hye-sook Lee),박은옥(Eun-ok Park) 한국보건교육건강증진학회 2003 보건교육건강증진학회지 Vol.20 No.3

제주도 1개 군 지역에서의 취학 전 아동의 영양상태 조사

홍성철(Seong-Chul Hong),이상이(Sang-Yi Lee),고순배 한국농촌의학 지역보건학회 2002 농촌의학·지역보건 Vol.27 No.1

파라메트릭 기술기반 철근 콘크리트 구조물의 기둥부재 자동배근시스템 구축에 관한 연구

홍성욱(Hong Seong-Uk),조영상(Cho Young-Sang),이제혁(Lee Je-Hyuk),홍성철(Hong Seong-Chul) 대한건축학회 2011 大韓建築學會論文集 : 構造系 Vol.27 No.1

Recently, as there has been high interests in Building Information Modeling (BIM), there are studies and movements to adapt this new paradigm in both academic field and industrial field. While, Reinforced concrete structure is a mainly used structural system in Korea. However, it is limited the development of reinforced concrete system in BIM comparing to that of steel structures. The primary reason is that it is not interoperable the information on reinforcement in RC structures and the progress of modeling reinforcement has a low productivity for a reinforcement object being created manually by user in the BIM platform. For the requirements, ARPM(Automatic Reinforcement Placing Module) has been developed to connect structural analysis and design database to BIM platform, to perform the design of reinforcement placing and to draw reinforcement in BIM platform, in this study. By developing the ARPM, it is expected to raise the productivity of the construction for RC structures and increase the effectiveness in the current modeling process in BIM platform.

제주도 가임연령 여교사의 톡소포자충 항체 양성률

양현종,홍성철,배종면,Yang, Hyun-Jong,Hong, Seong-Chul,Bae, Jong-Myon 대한예방의학회 2001 Journal of Preventive Medicine and Public Health Vol.34 No.4

Objectives : Toxoplasmosis is a member of the zoonosis group and may cause congenital infection . Antibody positive rates of toxoplasmosis were examined in high school students in Cheju, Korea to facilitate the study aim of examining the seroprevalence of Toxoplasma gondii in school teachers of child-bearing age in Cheju Island. Methods : The study population comprised teachers of child-bearing age in primary, middle and high schools, aged 35 years and younger, who wished to be tested for Toxoplasma gondii antibodies (IgG) by the indirect latex agglutination test (ILA) and the enzyme-linked immunosorbent assay (ELISA) method. Results : The overall antibody positive rate was 3.8% in the study subjects (n=314), a rate which showed no significant difference due to birth place, history of bringing up pets, or history of contacting a cat. Conclusion : We confirmed that the seroprevalence of Toxoplasma gondii in a population of child-bearing teachers in Cheju Island was the same as that previously reported in other parts of Korea.

제주도 가임 여교직원의 풍진 항체 보유율 조사

양현종,홍성철,배종면,Yang, Hyun-Jong,Hong, Seong-Chul,Bae, Jong-Myon 대한예방의학회 2000 Journal of Preventive Medicine and Public Health Vol.33 No.3

Background : Congenital rubella syndrome (CRS) can be controlled by vaccination. Because rubella is typically a childhood disease, occurring predominantly in the 5 to 14 year age group, female school teachers nay be a high-risk population for CRS. Objectives : To determine the prevalence rate of rubella antibodies in school teachers of child bearing age. Methods : The study population consisted of primary, middle and high school teachers of child bearing age. The subjects were aged 35 years and younger, and consented to immunoglobulin (Ig) level testing using the ELISA method. Results : The positive rate of IgG was 77.9% in the study subjects (n=314). Sixty-three teachers (21.4%) were susceptible to rubella infection. Thirty-seven teachers (11.8%) had a history of rubella vaccination. Among the female teachers with no vaccination history, the proportion of negative IgM and IgG was 21.7%, and the proportion of positive IgM was 2.9%. Seventy-nine percent of the study subjects did not know that they should not become pregnant for three months after receiving the rubella vaccine. Conclusion : School teachers of child bearing age should be considered a high risk group for CRS, and should be vaccinated if they are found to be seronegative.

제주 지역 초등학교 고학년의 교내 집단따돌림 피해 경험 관련요인 : 우울 증상과 가족 환경적 요인을 중심으로

김문두,홍성철,정영은,Kim, Moon-Doo,Hong, Seong-Chul,Jung, Young-Eun 대한불안의학회 2017 대한불안의학회지 Vol.13 No.1

Objective : The purpose of this study was to evaluate the factors associated with the experience of bullying victimization in school among elementary school students in the Jeju area. Methods : A total of 662 students were recruited from elementary schools for a school-based cross-sectional survey (age range : 11-12 years) in the Jeju area. This study used a self-reported questionnaire concerning the experience of being victimized by bullying, the Korean form of the Children's Depression Inventory (CDI) to assess depressive symptoms, and questions on sociodemographic characteristics, including school- and family-related factors. Results : The prevalence of bullying victimization in school among elementary school students was 10.0% (n=66). The factors associated with bullying victimization were lower socioeconomic status, lower than average academic achievement, more depressive symptoms, and family problems. Conclusion : This study not only indicates that bullying at school is a significant public health issue among elementary school students, but also confirms that children with family problems commonly exhibit bullying behaviors, which highlights the importance of considering family-related environmental factors when managing bullying victimization.

제주도 주민의 소득계층에 따른 암 입원 의료이용의 차이

김철웅 ( Chul Woung Kim ),이상이 ( Sang Yi Lee ),홍성철 ( Seong Chul Hong ) 한국보건행정학회 2003 보건행정학회지 Vol.13 No.3

Equity in health care has taken priority in the Korean government`s policy agenda after the government-led national health insurance achieved universal coverage in 1989 along with the final inclusion of the self-employed as beneficiary. The purpose of this study is to examine the extent to which there exists difference or inequality in the utilization of health care, especially cancer inpatient services among income classes. We analysed the utilization of cancer inpatient services of residents in Jeju Island for a year of 2000, using the national health insurance data for qualification of beneficiaries and utilization of health care. The independent variable are 10 income classes based on the national health insurance fee imposed on each household for a year of 2000. The dependent variables of this study are an amount of cancer inpatient health care utilization measured by cancer admission days and cancer treatment costs. Also, cancer inpatient health care utilization is analysed by three categories divided into utilization in medical care institutions (1) within Jeju Island, (2) outside Jeju Island, and (3) all within and outside Jeju Island. We measured concentration index of cancer inpatient health care utilization. This analysis showed negative concentration index within Jeju Island and positive outside Jeju Island, and positive in all within and outside Jeju Island. This results suggest inequality against the relatively poor income groups in utilization of cancer inpatient health care services. Especially, inequity of cancer inpatient health care would be more serious in Jeju Island of Korea, considering that lower income groups reportedly have higher incidence rates in most of cancer and thus use more health services.

Draft genome sequence of Streptococcus constellatus KCOM 1039 isolated from human postoperative maxillary cyst lesion

박순낭,임윤경,홍성철,신자영,노한성,국중기,Park, Soon-Nang,Lim, Yun Kyong,Hong, Seong-Chul,Shin, Ja Young,Roh, Hanseong,Kook, Joong-Ki The Microbiological Society of Korea 2019 미생물학회지 Vol.55 No.1

Streptococcus constellatus is Gram-stain-positive, facultative anaerobic, and non-spore forming coccus. It is a member of normal flora of human oral cavity. S. constellatus KCOM 1039 was isolated from human postoperative maxillary cyst lesion. In this report, we present the draft genome sequence of S. constellatus KCOM 1039. Streptococcus constellatus는 그람 염색에 양성을 띄며, 조건 혐기성이면서 아포를 생성하지 않는 구균이다. S. constellatus는 사람 구강의 정상 세균 총에 속한다. 수술후 상악낭종 병소에서 S. constellatus KCOM 1039 균주가 분리되었다. 여기에서 S. constellatus KCOM 1039 균주의 유전체 염기서열을 결정하여 보고한다.