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      • KCI등재

        오존농도 시뮬레이션과 배출량 변화에 따른 민감도 분석

        한진석,김병곤,김신도,Han, Jin-Seok,Kim, Byung-Gon,Kim, Shin-Do 한국환경영향평가학회 1996 환경영향평가 Vol.5 No.1

        The variations of ozone concentration and the sensitivity test for VOC emission intensities was investigated by means of a PBM(Photochemical Box Model). Compared to monitoring data, the typical variations of $NO_2$, CO, $O_3$ for days were successfully reproduced. Model results revealed that maximum ozone concentration got increased with the increase of VOC emission, that is, VOC played the important role in producing the photochemical smog.

      • KCI등재

        흑연 동위원소 비율법의 지표 동위 원소 적합성 연구

        한진석,장준경,이현철,Han, Jinseok,Jang, Junkyung,Lee, Hyun Chul 한국방사성폐기물학회 2020 방사성폐기물학회지 Vol.18 No.1

        The Graphite Isotope Ratio Method (GIRM) can verify non-proliferation of nuclear weapon by estimating the total plutonium production in a graphite-moderated reactor. Using the reactor, plutonium is generated and accumulated through the <sup>238</sup>U neutron capture reaction, and impurities in the graphite are converted to nuclides due to the nuclear reaction. Therefore, the amount of plutonium production and concentration of the impurities are correlated. However, the plutonium production cannot be predicted using only the absolute concentration of the impurities. It can only be predicted when the initial concentration of the impurities is obtained because the concentration, at a certain time, depends on it. Nevertheless, the ratios of the isotopes in an element are known regardless of the impurity of an element in the graphite moderator. Thus, the correlation between the isotope ratio and amount of plutonium produced helps predict plutonium production in a graphite-moderated reactor. Boron, Lithium, Chlorine, Titanium, and Uranium are known as indicator elements in the GIRM. To assess whether the correlation between the indicator isotope and amount of plutonium produced is independent of the initial concentration of the impurities, four different impurity compositions of graphite were used. <sup>10</sup>B/<sup>11</sup>B, <sup>36</sup>Cl/<sup>35</sup>Cl, <sup>48</sup>Ti/<sup>49</sup>Ti, and <sup>235</sup>U/<sup>238</sup>U had a consistent correlation with the cumulative plutonium production, regardless of the initial impurity concentration of the graphite, because these isotopes were not generated through the nuclear reaction of other elements. On the other hand, the correlation between <sup>6</sup>Li/<sup>7</sup>Li and plutonium production depended on the initial concentration of the impurities in graphite. Although <sup>7</sup>Li can be produced through the neutron capture reaction of <sup>6</sup>Li, the (n, α) reaction of <sup>10</sup>B was the major source of <sup>7</sup>Li. Therefore, the initial concentration of <sup>10</sup>B affected the production of <sup>7</sup>Li, making Li unsuitable as an indicator element for the GIRM.

      • 대기 중 PM2.5, 미세먼지 바로 알기

        한진석 ( Jin-seok Han ) 한국환경농학회 2019 한국환경농학회 학술대회집 Vol.2019 No.-

        본 연구에서는 요즘 이슈가 되고 있는 미세먼지, 그 중에서도 PM2.5에 대해 알아보고자 하였다. PM2.5의 농도현황과 배출원, 구성성분, 생성기작 등의 물리적인 특징과 화학적 특징에 대해 알아 보고, PM2.5가 인체에 미치는 영향, PM2.5의 현황에 대해 알아보고자 하였다. 미세먼지는 1차 입자상물질(Primary Aerosol)과, 2차 생성 입자상 물질 (Sencondary Aerosol)로 분류할 수 있다. 2차 생성 입자상 물질은 대기중으로 배출된 SO<sub>2</sub>, NOx, VOCs와 같은 기체상 물질이 광화학반응과 같은 균질반응(Homogeneous Reaction)과 비균질반응(Heterogeneous Reaction)에 의하여 입자상으로 생성, 변화되어진 것이다. PM2.5 고농도 발생 시에는 일반적으로 1차 입자상 물질보다는 2차 생성 입자상물질의 기여율이 증가하는 특성을 나타낸다. 대기 중 PM2.5농도를 개선, 관리하기 위해서는 1차 입자상 물질의 발생원, 2차 생성 입자상 물질의 전구물질인 SO<sub>2</sub>, NOx, VOCs에 대한 관리와 함께 대기 중 생성, 반응 기작의 이해를 바탕으로 개선 전략을 추진해야 할 것이다. In this study, We wanted know about PM2.5 of fine particle, and about physical, chemical characteristic such as concentration, configuration constituent and emission source. The fine particle can be classified into primary aerosol and secondary aerosol. The secondary aerosol were generated by heterogeneous, homogeneous reaction of gaseous materials such as SO<sub>2</sub>, NOx, VOCs. When PM2.5 is generated at a high concentration, the contribution ratio of secondary aerosol increase rather than the primary aerosol. To improve and manage the concentration of PM2.5 in ambient air, it is necessary to manage for the emission source of primary aerosol, secondary aerosol(SO<sub>2</sub>, NOx, VOCs), and development strategies base on understanding of generation in ambient air and reaction mechanism.

      • 통합된 전산 응용 내구성 해석 알고리즘 개발

        한진석(J.S.Han),조종두(C.Cho) 한국자동차공학회 1997 한국자동차공학회 춘 추계 학술대회 논문집 Vol.1997 No.11_2

        An algorithm was developed for structural durability analysis. DADS. MSC/ NASTRAN. and MSC/FATIGUE were utilized as analysing tools of dynamics. statics. and fatigue. respectively. Using the proposed method seems to be practically usuable for durability analysis such as automobiles and machinery.

      • KCI등재후보

        한국형출혈열에서 Kallikrein - Kinin 활성에 관한 연구

        한진석(Jin Suk Han),이정상(Jung Sang Lee),이상구(Sang Koo Lee),김성권(Suhng Gwon Kim),고창순(Chang Soon Koh),이문호(Mun Ho Lee) 대한내과학회 1989 대한내과학회지 Vol.37 No.2

        N/A Although it has been suggested that the basic lesion of hemorrhagic fever with renal syndrome in Korea (Korean hemorrhagic fever) is the vasculopathy consisted of dilatation of generalized small vessels, increased permeability, permeation of plasma components and diaphedesis of blood cells, its pathophysiologic mechanism has been under debate. We purposed to investigate the role of kallikrein-kinin in the vasculopathy and its relation with the clinical findings of Korean hemorrhagic fever. We measured serially plasma prekallikrein, kallikrein and kallikrein inhibitor activities by amidolytic assay with synthetic substrate and compared with the variable clinical indices that has been regarded as the prognostic factors. The results obtained as follows; 1) The plasma prekallikrein activities were significantly reduced and kallikrein activities were significantly elevated in the group of the 5~7th day of illness compared to those of .15~21st and over 22nd day (p<0. 05, Scheffe's test). But those of kallikrein inhibitor were elevated in the earlier day of illness without significant change during the course. 2) The plasma prekallikrein activities were significantly reduced in the hypotensive phase compared to those of the febrile phase, and in the hypotensive and oliguric phases compared to those of the diuretic and convalescent phases (p<0.05, Scheffb's test). The plasma kallikrein activities were significantly elevated in the hypotensive phase compared to those of all the other phases, and in the oliguric phase compared to the diuretic and convalescent phases (p<0.05, Scheffe's test), But those of kallikrein inhibitor were elevated without significant change in each phase. 3) The plasma prekallikrein activities were significantly reduced in the groups with primary shock, severe azotemia, leukocytosis and thrombocytopenia. Those of kallikrein were significantly elevated in the group with primary shock, hemoconcentration, leukocytosis, thrombocytopenia and higher scores of clinical severity. 4) In the 11 cases with kallikrein activation, clinical characteristics were shorter days from onset to admission, higher scores of clinical severity, hematocrit, leukocyte counts, and lower thrombocyte couots and initial creatinine. 5) The plasma Cl inhibitor were elevated without significant change in the day of illness or each phase. And there was a good correlation between plasma kallikrein inhibitor and C1 inhibitor (r=0.76, p<0.01). Thus we concluded that the activation of kallikrein-kinin in Korean hemorrhagic fever plays significant role in the pathophysiologic mechanism and is related with primary shock, hemoconcentration, leukocytosis, thrombocytopenia and clinical severity.

      • SCOPUSKCI등재

        만성신부전에서 염류코르티코이드 투여가 포타시움 평형과 요 암모늄 배설에 미치는 효과

        한진석(Jin Suk Han),이정상(Jung Sang Lee),김강석(Kang Seock Kim),허우성(Woo Seong Huh),전은실(Un Sil Jeon),이서진(Seo Jin Lee),주권욱(Kwon Wook Joo),김성권(Suhnggwon Kim),진호준(Ho Jun Chin),조윤숙(Yun Suk Cho) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.2

        N/A Mineralocorticoids influences on acid-base homeo-stasis by the regulation of urine acidification. But its mechanism of acion is not well known in human. This study compared the acid-base status and the indices of urine acidification before and after mineralocorticoid administration in human, and analyzed the effect of mineralocorticoids on human acid-base homeostasis. We administered 9a-fludrocortisone in 6 chronic renal failure patients and 6 normal controls 0.5mg daily for 7 days. The results were as following ' 1) After administration of 9a-fludrocortisone in patients group, serum aldosterone level changed from 120.2±71.0pg/mL to 44.8±32.2pg/mL(mean±SD, p< 0.05). Serum HCO- level was not changed. Urine ammonium excretion was incresed from 24.6±12.3 mmol/day to 43.7±19.0(p<0.05), but there were no change in urine pH and urine anion gap, Serum potassium level decreased from 5.5±0.7mBq/L to 4.1±0.5mEq/L(p<0.05), and TTKG increased from 3.9 to 8.9(p<0.05). 2) After administration of 9a-fludrocortisone in control group, serum aldosterone level changed from 99.7±44.5pg/mL to 25.1±3 mL(p<0.05). Serum HCO- level was not changed. Urine ammonium ex-cretion was incresed from 44.3±21.6mmoVday to 76.3±19.6(p<0.05), but there were no change in urine pH and urine anion gap. Serum potassium level decreased from 4.8±0.5mEq/L to 3.9±0.2mHq/L(p< 0.05), but there was no change in TTKG. 3) No patient or control showed any discomfort after 9-fludrocortisoneadministration, and there was no elevation in diastolic blood pressure, increase in body weight, electrolyte abnormality. In summary, after 9α-fludrocortisane administration, urinary ammonium excretion increased in both patients and control group, and this phenomenon occured with correction of hyperkalemia without urine pH change. This result implies urinary ammonium excretion increase by mineralocorticoid. In human increase in renal distal acidification by mineralocorticoid is due to increase in renal ammo- niagenesis rather than stimulation on proton excretion.

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