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- 저자 : 최병흔(Byung-Heun Choi) (검색결과 6 건)
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윤석근(Seok Keun Yoon),최병흔(Byung Heun Choi),박헌웅(Hun Woong Park) 대한두경부종양학회 1987 대한두경부 종양학회지 Vol.3 No.1
The syndrome of inappropriate ADH secretion (SIADH) is a clinical disorder in which there is continual release of antidiuretic hormone (ADH) unrelated to plasma osmolality. ltmay occur usually in association with malignant tumors below the clavicle and other pulmonary disorders which are capable of synthesizing, storing and releasing ADH into the circulation but rarely with the head and neck tumors yet. We experienced a patient with unexplained hyponatremia associated with laryngeal carcinoma. The clinical and laboratory diagnostic studies suggested that patient's sodium deficiercy was secondary to the SIADH. Subsequent resection of the neoplasm, total laryngectomy led to resolution of hyponatremia, suggesting that a tumor associated humoral factor, such as vasopressin or vasopressin like substance, was responsible for the electrolyte disturbance.
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후두 내시경(Fiber-Optic Nasolaryngoscope)을 이용한 말더듬인의 후두양상에 관한 연구
정훈(Hun Jung),안종복(Jong-Bok Ahn),최병흔(Byung-Heun Choi),권도하(Do-Ha Kwon) 한국음성학회 2008 음성과학 Vol.15 No.3
The purpose of this study was to use fiber-optic nasolaryngoscope to find outdifferences in laryngeal behavior between persons who stutter(PS) and those who do not stutter(NS) upon their utterance. To meet the goal above, this study took 5 NS and 5 PS respectively as a part of sampling, so that they were all asked to join an experiment hereof. As a result, this study came to the following findings: First, there was not any significant difference in laryngeal behavior of uttering spoken languages between stuttering group and control. Second, there were some differences in laryngeal behavior of repetition and prolongation, which were a sort of disfluency revealed in the utterance of nonfluent spoken languages between stuttering group and control. Third, as reported by prior studies, it was found that there were differences in laryngeal abehavior of stutterer group's nonfluent spoken languages depending upon stuttering types. In this study, a variety of laryngeal behavior unreported in prior studies could be found. In addition, it was notable that stutterers showed different laryngeal behavior depending on their personal stuttering types. On block condition, Subject 1 showed laryngeal behavior of fAB, INT and fAD; Subject 2 showed laryngeal behavior of fAB, fAD and rAD; Subject 3 showed laryngeal behavior of fAD and rAD; Subject 4 showed only laryngeal behavior of fAD; and Subejct 5 showed laryngeal behavior of fAB, fAD and rAD. Summing up, these findings imply that when stutterers utter nonfluent words, they may reveal a variety of laryngeal behavior depending on their personal stuttering types. Moreover, it is found that there are more or less differences in the utterance of nonfluent spoken languages between NS and stuttering ones. In particular, it is interesting that one common trait of nonfluent spoken languages uttered by PS is evidently excessive laryngeal stress, no matter which type of stuttering they reveal.
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내전형연축성 발성장애 음성에 대한 켑스트럼과 스펙트럼 분석
심희정(Shim, Hee Jeong),정훈(Jung, Hun),Lee, Sue Ann,최병흔(Choi, Byung Heun),허정화(Heo, Jeong Hwa),고도흥(Ko, Do-Heung) 한국음성학회 2016 말소리와 음성과학 Vol.8 No.2
The purpose of this study was to analyze perceptual and spectral/cepstral measurements in patients with adductor spasmodic dysphonia(ADSD). Sixty participants with gender and age matched individuals(30 ADSD and 30 controls) were recorded in reading a sentence and sustained the vowel /a/. Acoustic data were analyzed acoustically by measuring CPP, L/H ratio, mean CPP F0 and CSID, and auditory-perceptual ratings were measured using GRBAS. The main results can be summarized as below: (a) the CSID for the connected speech was significantly higher than for the sustained vowel (b) the G, R and S for the connected speech were significantly higher than for the sustained vowel (c) Spectral/cepstral parameters were significantly correlated with the perceptual parameters, and (d) the ROC analysis showed that the threshold of 13.491 for the CSID achieved a good classification for ADSD, with 86.7% sensitivity and 96.7% specificity. Spectral and cepstral analysis for the connected speech is especially meaningful on cases where perceptual analysis and clinical evaluation alone are insufficient.
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長期間 高鹽 攝取한 쥐에서 calcium 이 angiotensin Ⅱ 와 vasopressin 에 대한 昇壓反應에 미치는 影響
崔秉欣,黃駿河,朴載植,李元晶 慶北大學校 醫科大學 1987 慶北醫大誌 Vol.28 No.2
고염 섭취한 쥐에서 Ca^++주입 전후의 Ang Ⅱ와 AVP에 대한 승압반응을 비교하였다. 젖 떨어진 생후 5주의 Wistar 숫쥐에게 Na^+이 0.5mM/100g(저염) 또는 25mM/100g(고염)이 포함된 사료를 먹였다. 실험 식이를 12주 섭취시킨 후에는 쥐를 ether로 마취시킨 다음, 대퇴동맥과 정맥에 catheter를 삽입하였다. 수술 후 마취가 깨고 두시간정도 기다려 혈압이 안정된 다음 Ang Ⅱ와 AVP5-250ng/㎏를 정맥 주사하여 용량에 대한 승압반응을 기록하였다. 그 후 CaCl_2 용액을 한시간동안 주입(750㎍ Ca^++/100g/hr)한 다음, Ca^++을 계속 주입하는 상태에서 앞의 방법으로 Ang Ⅱ와 AVP를 주사하여 각각의 용량에 따른 승압반응을 실험하였다. 고염 섭취한 쥐에서는 Ang Ⅱ에 대한 승압반응이 저염군보다 유의하게 높았다. 그러나 AVP에 대한 승압반응은 두 군 사이에 차이가 없었다. Ca^++주입하는 동안 혈장의 Ca^++농도나 안정시 혈압에는 유의한 변화가 없었으나, 심박수는 감소하였다. Ca^++주입하는 동안의 Ang Ⅱ와 AVP에 대한 승압 반응은 1.5배 정도 현저하게 증가하였다. 이 때에도 역시, Ang Ⅱ에 대한 승압반응은 고염군이 저염군 보다 높았는데, 두 군 사이의 차이는 Ca^++주입 전보다 월등히 많았다. Ca^++주입시 AVP에 대한 승압반응은 두군 사이에 차이가 없었다. 이상의 결과로 소금 섭취량에 따라 Ang Ⅱ에 대한 순환계의 반응이 변화함을 알 수 있었다. 혈장 Ca^++농도가 소량 변화할 때 심근이 혈관근육보다 더 예민하게 영향을 받으며, Ca^++은 Ang Ⅱ나 AVP의 승압반응을 증가시켰다. Pressor responses to Ang Ⅱ and AVP berfore and after Ca^++ infusion were compared in male Wistar rats fed low (0.5mM Na^+/100g diet) or high salt (25mM/100g) diet. Experimental diets were fed for 12 weeks from 5 week old. Then catheters were inserted in femoral artery and vein under ether anesthesia. After arterial pressure had stabilized for 2 hr, the pressor responses to graded i.v. injection of Ang Ⅱ and AVP were determined in each rats. The dose-response curves were examined during Ca^++ infusion (750㎍/100g/hr). Rats fed high salt diet showed significantly greater pressor response to Ang Ⅱ than the low salt group. However, there was no difference in pressor responses to AVP between sodium loaded and restricted rats. Ca^++ infusion produced no significant change in plasma Ca^++ level or arterial pressure, but significant decrease in heart rate. Pressor responses to Ang Ⅱ and AVP during Ca^++ infusion were increased about 1.5-fold. Pressor response to Ang Ⅱ during Ca^++ infusion was also greater in rats fed high salt diet, and the difference between the two groups was much greater than that before Ca^++ infusion. Pressor response to AVP during Ca^++ infusion was similar in the two groups. These results indicate that sodium balance influences the action of Ang Ⅱ on vascular systems. Cardiac muscle responded to Ca^++ more sensitively than blood vessels, and Ca^++ increased the vascular responses to Ang Ⅱ and AVP.
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