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RISS 인기검색어
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- 저자 : 최경은 ( Kyong Eun Choi ) (검색결과 3 건)
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복수로 발현된 비 IgE 매개성 호산구성 위장관염 1예
이은상,김미진,하상윤,이유민,최경은,최연호,Yi, Eun-Sang,Kim, Mi-Jin,Ha, Sang-Yun,Lee, Yoo-Min,Choi, Kyong-Eun,Choe, Yon-Ho 대한소아소화기영양학회 2011 Pediatric gastroenterology, hepatology & nutrition Vol.14 No.2
저자들은 구토, 설사와 같은 비특이적인 증상과 복수가 발생한 13세 남아에서 말초혈액의 호산구 증가 소견이 있고 IgE는 정상범위이며, 내시경 생검상 식도, 소장, 대장 및 직장에서 특징적인 호산구 침윤 소견이 관찰되어 비 IgE 매개성 호산구성 위장관염으로 진단된 1예를 경험하였으며 스테로이드 투여로 증상 호전을 보였기에 문헌고찰과 함께 보고하는 바이다. Eosinophilic gastroenteritis is a rare disease occurring especially in children, and shows various nonspecific presentations with infiltration of eosinophils in the gastrointestinal organs. The pathophysiology of eosinophilic gastroenteritis is not yet clearly known, but allergic reactions are suspected to be related with the disease. Eosinophilic gastroenteritis is categorized into the mucosal, muscularis and subserosal types based on which layer of the intestinal wall is involved. There are different clinical manifestations according to the involved layer. Most cases to date have responded well to steroid therapy. In this study, we diagnosed and treated a case of non-IgE-mediated, subserosal eosinophilic gastroenteritis in a child with abdominal pain, diarrhea and ascites.
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Mycoplasma pneumoniae 폐렴으로 입원한 소아의 Macrolide 내성과 치료 양상
강국진 ( Kook Jin Kang ),고정희 ( Jeong Hee Ko ),최경은 ( Kyong Eun Choi ),최유미 ( Yu Mi Choi ),이원욱 ( Won Wuk Lee ) 중앙대학교 의학연구소 2018 中央醫大誌 Vol.43 No.1
Pediatric Mycoplasma pneumoniae (M. pneumoniae) infection in Korea is becoming difficult to treat due to the recent rise in macrolide resistance. In this study, we investigated the macrolide resistance rate, clinical features, and treatment response of mycoplasma pneumonia patients. The 23S rRNA gene mutations in 247 patients with M. pneumoniae pneumonia were analyzed and grouped into either macrolide-resistant mycoplasma pneumonia (MRMP) and macrolide-susceptible mycoplasma pneumonia (MSMP) patients. Among patients with mycoplasma pneumonia, 85.8% had MRMP and all were mutations of A2063G. All patients received macrolide antibiotics and received steroid therapy in patients with unresponsive to macrolide. Total fever days was significantly longer in MRMP (7.3 days) than in MSMP (5.6 days, p = 0.009), and febrile days after initiation of macrolides was longer in MRMP (2.1 days) than that of MSMP (1.1 days, p = 0.003). In laboratory finding, only lactate dehydrogenase was significantly higher in MRMP (p = 0.026). The steroid treatment rate was significantly higher in MRMP (36.7%) than MSMP (14.2%) (p = 0.011) and the duration of use was significantly longer in MRMP (3 days) than MSMP (1 day, p = 0.039). The results of this study suggest that steroid therapy can help lower the duration of total treatment in children with macrolide-resistant mycoplasma pneumonia. Chung-Ang J Med 2018; 43(1): 7-13
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단일 기관에서 경험한 호흡기 아데노바이러스 감염의 임상적 고찰
김태현 ( Tae Hyun Kim ),임정혁 ( Chung Hyuk Yim ),안성윤 ( Sung Yoon Ahn ),강국진 ( Kook Jin Kang ),최유미 ( Yu Mi Choi ),고정희 ( Jeong Hee Ko ),최경은 ( Kyong Eun Choi ),이정현 ( Jung Hyun Lee ),이원욱 ( Won Wook Lee ) 대한천식알레르기학회 2015 Allergy Asthma & Respiratory Disease Vol.3 No.6
Purpose: The purpose of this study is to identify the epidemiologic and clinical characteristics of respiratory adenovirus infections in children, and to investigate the difference in the clinical features between single adenovirus infection and coinfection with adenovirus and other respiratory viruses. Methods: A retrospective study was performed in 470 children hospitalized with respiratory adenovirus infections in Gwangmyeong Sungae Hospital between January 2013 and December 2013. Results: The mean age of the patients was 46.2 months and the peak incidence was in the 12- to 24-month age group. The mean duration of hospitalization and fever were 4.5±1.1 and 4.5±9.2 days, respectively. Seasonally it had occurred throughout the year, but showed the highest prevalence in August and high prevalence in July, September, and October. The frequency of viral coinfection with other respiratory viruses was 39.6%. The age was significantly younger in coinfection group than in the single adenovirus infection group (P<0.001). The prevalence rates of bronchiolitis (P<0.001) and pneumonia (P=0.042) were significantly higher in the respiratory syncytial virus coinfection group. The coinfection rate was significantly higher in children aged less than 2 years (P<0.001), and the prevalence rates of bronchiolitis (P<0.001) and pneumonia (P<0.001) were also higher in the group aged less than 2 years than other age groups. Conclusion: Adenovirus is an important viral agent in hospitalized children with acute respiratory tract infection. Lower respiratory tract infections, such as bronchiolitis and pneumonia, and coinfection with other respiratory viruses were more frequently occurred in patients under 2 years of age. Further studies are needed to clarify whether coinfection with other respiratory viruses would increase the rate of lower respiratory tract infections in patients with respiratory adenoviral infections. (Allergy Asthma Respir Dis 2015;3:402-409)
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