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주갑순(Kap Soon Ju),이희경(Hee Kyung Lee) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.1
N/A Objective: A cytogenetic survey of the mentally retarded children in Seoul City Welfare Center for the Mentally Retarded and St Peter school has been undertaken. Methods: The chromosome analysis was carried out in 92 males and in 66 females as a total of 158 cases. Results: Abnormal karyotypes were observed in 22.2% of the total cases (35/158). Autosome and sex chromosome anomaly were observed in 20.3%(32/158) and 1.9%(3/158) respectively. Of 35 cases of anomaly, 91.4%(32/35) was autosome anomaly and 8.6%(3/35), sex chromosome anomaly. Conclusion: Down syndrome karyotype was the most frequent anomaly among autosome anomalies which was 62.5%(20/32) and other autosome anomalies were observed in 37.5%(12/32).
여성 생식기 염증에서 Chlamydia trachomatis , Mycoplasma hominis , Ureaplasma urealyticum 의 검출
이해혁(Hae Hyeog Lee),주갑순(Kap Soon Ju),이권해(Kwon Hae Lee),원남희(Nam Hee Won) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.3
N/A Objective: A polymerase chain reaction (PCR) was developed in the detection of Chlamydia(C) trachomatis, Mycoplasma(M) hominis and Ureaplasma(U) urealyticum, which have been common causes of sexual transmitted diseases in the female genital tracts and in neonatal infection. To investigate tbe frequency of these organisms in the female genital tract infection and to know any association of these infections with clinical manifestations, PCR was performed. Methods: PCR was performed in 300 cases of vaginal swabs and 154 paraffin embedded tissues including 50 cases of chronic endometritis, 50 cases of cleonic salpingitis, 50 cases of ectopic tubal pregnancy and 4 cases of normal endometrium. Results: Among 300 cases of vaginal swabs, C. trachomatis, M. hominis and U. urealyticum were detected in 1.3%, 4.0%, and 29.6%, respectively. Mixed infection was found in 12.0%. the overall positive rate was 47.0%. The cytologic features from C. trachomatis, M. hominis and U. urealyticum positive patients revealed no specific findings. The clinical manifestations between positive and negative cases for these organisms had no differences. In tissue samples, only C. trachomatis was detected 2% of chronic endometritis, 8% of chronic salpingitis and 4% of ectopic tubal pregnancy. Conclusion: With the above results, it suggests C. trachomatis can evoke an ascending chronic infection of the female genital tracts and ectopic tubal pegnancy,
한국인 고혈압증 산모 가계에서 미토콘트리아 전이 리보핵산 유전자의 돌연 변이에 관한 연구
지일운(Ill Woon Ji),김학순(Hak Soon Kim),주갑순(Kap Soon Ju) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.2
N/A Objective: This study was performed to find out mitochondrial deoxyribonucleic acid mutations in preeclampsia because Mendelian models fail to explain all the patterns of inheritance in preeclampsia. Methods: Ten preeclampsia patients and two of their related family members who have the obstetric history of preeclampsia were studied. The mitochondrial transfer ribonucleic acidleu[UUR] gene was amplified using polymerase chain reaction, cut by a restriction endonuclease (Apa , and also sequenced to see the whole gene. Results: There were neither the known mutation at Nucleotide 3243 nor other mutations on the mitochondrial transfer ribonucleic acidleu[UUR] gene in these objects. Conclusion: It seems that the known mutation of mitochondrial transfer ribonucleic acidleu[UUR] gene is not so frequently detected in preeclampsia of South Korean, But it could not be concluded how many South Korean women with preeclampsia have the mutation.
호르몬 대체요법을 받고있는 폐경 후 여성에서 부정기 질 출혈과 동반된 부인과적 처치 : 주기적 호르몬 대체요법과 지속적 병합 호르몬 대체요법의 비교
이미정(Mi Jung Lee),나정아(Jeong A Na),김인호(In Ho Kim),허준용(Jun Young Hur),박용균(Yong Kyun Park),주갑순(Kap Soon Ju),서호석(Ho Suk Saw),조수용(Soo Yong Chough) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.2
목적: 호르몬 대체 요법을 시행하고 있는 폐경후 여성에서 부정기 질 출혈이 있는 경우와 그 때 동반된 부인과적 처치를 알고자 하였다. 연구 대상 및 방법: 1996년 1월에서 1998년 12월까지 고려대학교 의과대학 부속 구로 병원 외래를 방문한 호르몬 대체 요법을 받고 있는 폐경후 여성들을 대상으로 비정상적인 부정기 질 출혈이 있는 여성들을 추출하여 관련된 방문과 부인과적 처치들을 평균 2년의 추적기간 동안 기록하였다. 결과: 주기적 호르몬 대체 요법을 받고 있는 여성에서는 28.9%가 1회 이상의 부정기 질 출혈이 있었고 8.7%가 1회 이상의 자궁 내막 생검을 시행 받았다. 지속적 병합 호르몬 대체 요법을 받고 있는 여성에서는 19.3%가 1회 이상의 부정기 질 출혈이 있었고 6.4%가 1회 이상의 자궁 내막 생검을 시행 받았다. 동반된 부인과적 처치의 내용을 보면 주기적 호르몬 대체 요법을 받고 있는 여성에서 20%가 독려, 50%가 초음파, 30%가 자궁내막 생검을 시행 받았고 지속적 병합 호르몬 대치 요법을 받고 있는 여성에서는 50%가 독려, 16.6%가 초음파, 33.3%가 자궁 내막 생검을 시행 받았다. 결론: 부정기 질 출혈은 지속적 병합 호르몬 대체 요법을 받고 있는 여성에서는 12개월의 치료 후에 크게 감소하였으나 주기적 호르몬 대체 요법의 여성에서는 큰 변화가 없었다. Objective: To measure gynecologic resources required to care for women who have unscheduled vaginal bleeding while using hormone replacement therapy. Materials and Methods: Between January 1996 to December 1998, women presenting with abnormal withdrawal bleeding on HRT were identified and associated clinic visits and gynecologic procedures were recorded during a mean follow-up of 2 years. Results: Among women using cyclic HRT, 28.9% had≥1 visit for unscheduled vaginal bleeding 8.7% had≥1 endometrial biopsy. Among women using continuous combined HRT, 19.3% had≥1 visit for unscheduled vaginal bleeding and 6.4% had≥1 endometrial biopsy. The gynecologic procedures used in women using cyclic HRT were 20% of reassurance, 50% of ultrasonograpy, 30% of endometrial biopsy and in women using continuous combined HRT were 50% of reassurance, 16.6% of ultrasonograpy, 33.3% of endometrial biopsy. The results of endometrial biopsy were reported all the benign condition. Conclusion(s): Unscheduled vaginal bleeding markedly decreased after 12 months of therapy in women using continuous combined HRT but did not decline among those using cyclic HRT.
朱甲順,韓鍾卨,李在玄 慶熙大學校 1979 論文集 Vol.9 No.-
The follow-up studies on the outcome of pregnancy and infant having amniocentesis during midpregnancy were analized. Only 483 pregnant women gave the informations for the follow-up study among 1453 patients having amniocentesis during midpregnancy from Jan. 1976 to Dec. 1978 at the department of Obstetrics and Gynecology, Kyung Hee University Hospital. The results were as follows: 1. The 483 pregnant women having amniocentesis gave fullterm delivery in 457 (94.62%), premature delivery in 8 (1.86%), immature delivery in 2 (0.41%) missed abortion in 1 (0.21%), induced abortion in 3 (0.41%) and on pregnancy in 10 (2.07%). 2. Of 473 births, 4 still births, 9 neonatal deaths and 4 infant deaths were encountered. 3. Artificial inductions of the pregnancy were carried out in 3 cases such as a 47 XYY syndrome of the fetus, an anencephalus and a patients who had vaginal leakage of amniotic fluid after amniocentesis. 4. A total of 29 patients complained as follows: Abdominal pain in 15, amniotic leakage in 5, vaginal spotting in 4, amniotic fluid leakage with abdominal pain in 4 and vaginal spotting combined with vaginal leakage in 1. 5. The risks involved in amniocentesis for prenatal diagnosis are in our experience small, so that even the use of relative indication for sampling is justified. However, even if there are no increased statistical risk, there should be carried out by experienced obstetricians. 6. Of 278 term deliveries, 63 (22.66%) cases had permanent contraceptions such as tubal ligations or vasectomies and 100 (35.9%) cases are on temporary contraceptives after delivery.