http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Kim, Myeong Ok,Lee, Jeoung Sook,Cho, Kyeong Je,Lee, Bong Hee,Lee, Byung Ju,Choi, Wan Sung 경상대학교 유전공학연구소 1992 遺傳工學硏究所報 Vol.11 No.-
hypothalamic GnRH neurons are originated from olfactory placode of embryo.They enter brain regions during embryonic development and are loosely distributed within hypothalamic area and other brain regions. In the adult animals, however, GnRH is yet not known to be locally expressed in the olfactory cortex. Therefore, present study initially aims to acertain whether GnRH mRNA in the rat brain with in situ hybridization histochemistry. Interestingly, GnRH mRNAs are highly concentrated in the olfactory cortex of brain. To further elucidate the nature of GnRH transcripts in the olfactory system involving olfactory cortex and bulbs, we employed Northern hybridization and PCR analysis. GnRH mRNA in the rat olfactory cortex and bulb is similar in size to that in hypothalamus. The size of PCR products of olfactory cortex and bulbs are same with that of hypothalamus. Therefore, we suggest that GnRH in the olfactory system is expressed through a similar machinery with hypothalamic GnRH.