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High-dose caspofungin salvage in a very-low-birth-weight infant with refractory candidemia
서은선,박근화,정혜안,김병국,김성미 대한소아청소년과학회 2010 Clinical and Experimental Pediatrics (CEP) Vol.53 No.2
Candidiasis is one of the most common causes of late-onset infection among very-low-birth-weight infants (VLBW) in most neonatal intensive care units and is associated with significant morbidity and mortality. Standard therapy consists of the administration of amphotericin B, amphotericin B complex, and fluconazole. In many cases, candidiasis is not easily eradicated, despite the administration of these drugs. We report our experience of the addition of high-dose caspofungin to the conventional antifungal drugs in a VLBW infant with refractory candidemia.