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열간단조용 비조질강의 기계적 성질에 미치는 V, Nb의 영향
위겸복,정운태,이경섭,왕성도,Wee, Kyeom-Bok,Jeong, Woon-Tae,Lee, Kyeong-Seop,Wang, Seong-Do 한국재료학회 1992 한국재료학회지 Vol.2 No.1
0.4wt% C을 함유하는 기존의 기계구조용 탄소강에 V과 Nb을 단독 또는 복합으로 첨가한 열간단조용 비조질강의 기계적 성질을 조사하고, 미세조직과 셔출물의 분포 및 형상을 관찰하였으며 첨가원소의 영향을 정량화 하기 위해 중회귀분석을 행하였다. 인장시험 결과 모든 재료의 인장강도는 $70kg/\textrm{mm}^2$ 이상으로 기존의 소입.소려재(S45C)와 동등하거나 그 이상이었으며, 충격시험 결과 대부분 재료의 충격에너지는 40J 이하로 기존 재료의 약 50%정도였 다. V함량이 0.10에서 0.l5wt%로 증가하였을 경우 인장강도는 약 20% 증가하였으나 충격에너지는 감소하였다. 이는 VC의 미세석출에 의해 석출강화 효과와 함께 펄라이트의 부피분율이 증가하고 층간거리가 감소했기 때문이다. 반면 Nb 함량이 0.05에서 0.10wt%로 증가한 경우에는 강도와 인성의 근소한 증가경향을 나타내었다. 이는 NbC의 석출애 의한 결정립 미세화 효과가 VC 보다 우세했기 때문이다. 또한 V+Nb의 복합첨가는 단독첨가시에 비하여 충격인성의 향상에 보다 효과적이었으며, 본 실험에서 최적 강도와 인성의 조합을 보인 합금조성은 0.4C-1.19Mn-0.05S-0.12V-0.07Nb로 인장강도는 $84kg/\textrm{mm}^2$ 이상, 충격인성은 34J 이상이었다. 0.4wt%C steel added with V and/or Nb were forged and followed by air cooling. The structure-property relationships were examined and multiple regression analysis was conducted to quantify the magnitudes of effects of microalloying elements on the properties of the steels. All material's tensile strength are greater than $70kg/\textrm{mm}^2$, so they are equal to or superior to Q/T material's(S45C). Their impact energies are less than 40J, so they are 50% of Q/T material's. Increasing the content of V from 0.10 to 0.15 wt% had brought improvement in UTS about 20% but with some sacrifice of impact energy. These were the results from the precipitation strengthening by fine dispersion of VC in ferrite, increment of pearlite volume fraction and decrement of pearlite interlamellar spacings. However, increasing the content of Nb from 0.05 to 0.l0wt % slightly improved UTS and impact energy. NbC precipitates were more effective in suppression of austenite grain coarsening than VC precipitates. Combined additions of V+Nb were more effective to bring impact toughness than sole addition. Optimum combination of strength and toughness was accomplished wish 0.4C-1. 19Mn-0.05S-0.12V-0.07Nb steel.
증례 : 소화기 ; 췌장의 신경내분비종양으로 오인한 고형 변이성 장액성 낭종 1예
장현정 ( Hyun Jeong Jang ),김태효 ( Tae Hyo Kim ),이제운 ( Jae Un Lee ),김현식 ( Hyeon Sik Kim ),주지현 ( Ji Hyeon Ju ),정운태 ( Woon Tae Jung ),이옥재 ( Ok-jae Lee ) 대한내과학회 2015 대한내과학회지 Vol.89 No.1
췌장에서 발생하는 장액성 낭종 중에서 고형 변이성 장액 성 낭종은 매우 드물게 발생하는 질환이지만 악성 혹은 전 암성 병변과의 감별이 어려워서 수술이 필요한 다른 질환으 로 오인되는 경우가 매우 많다. 이에 저자들은 췌장의 신경 내분비종양으로 오인하고 수술을 시행하여 고형 변이성 장 액성 낭종으로 진단된 매우 드문 증례를 경험하였기에 문헌 고찰과 함께 보고한다. Rapid advancements, access to and use of imaging techniques have increased the frequency of identification of pancreatic cystic neoplasms in clinical practice. However, a diagnostic dilemma among pancreatic cystic neoplasms remains. Solid variant serous cystadenoma is extremely rare and difficult to accurately diagnose preoperatively, as they are commonly mistaken for malignant solid tumors of other types. Here, we present a case of a solid variant serous cystadenoma preoperatively misdiagnosed as a neuroendocrine tumor of the pancreas with a review of the relevant literature. (Korean J Med 2015;89:69-73)
안연정 ( Yeon Jeong Ahn ),김태효 ( Tae Hyo Kim ),문성원 ( Sung Won Moon ),최수녕 ( Su Nyoung Choi ),김현진 ( Hyun Jin Kim ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ),고경혁 ( Gyung Hyuck Ko ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.3
Xanthogranulomatous cholecystitis is an unusual inflammatory disease of the gallbladder characterized by severe proliferative fibrosis and the accumulation of lipid-laden macrophages in areas of destructive inflammation. Its macroscopic appearance may occasionally be confused with gallbladder carcinoma. We present a case of perforated xanthogranulomatous cholecystitis presenting as biloma. An 80-year-old woman was referred to our hospital with a 1-week history of abdominal pain and febrile sensation. Abdominal CT showed a biloma in the subhepatic area. The follow-up CT showed that the biloma increased in size. Therefore, ultrasonography-guided aspiration was performed. The aspirated fluid/serum bilirubin ratio was greater than 5, which was strongly suggestive of bile leakage complicated by perforated cholecystitis. She underwent a laparoscopic cholecystectomy with cyst aspiration and adhesiolysis. A histological diagnosis of perforated xanthogranulomatous cholecystitis was made. (Korean J Gastroenterol 2011;58:153-156)
위장관염과 장간막 림프절병증으로 발현한 제한성 베게너 육아종증 1예
정용근 ( Yong Geun Jeong ),김태효 ( Tae Hyo Kim ),이창민 ( Chang Min Lee ),심기식 ( Ki Shik Shim ),문인규 ( In Kyu Moon ),이상일 ( Sang Il Lee ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ) 대한소화기학회 2010 대한소화기학회지 Vol.55 No.5
Wegener`s granulomatosis (WG) is a disease characterized by a granulomatous necrotizing vasculitis of small vessels. Although any organ systems can be involved, gastrointestinal involvement in WG is notably uncommon. We present a case of 67-year-old man who was admitted with abdominal pain and diarrhea lasting for 3 weeks. Colonoscopy and abdominal CT scan revealed vasculitis and multiple mesenteric lymphadenopathy. Jejunum and mesenteric lymph nodes biopsies confirmed limited form of WG. The present case indicates that WG might involve only gastrointestinal tract and the histological confirmation is important for diagnosis. (Korean J Gastroenterol 2010;55:331-335)
증례 : 소화기 ; 전위절제술 후 발생한 복강내 유건종의 자연소실
문인규 ( In Kyu Moon ),김태효 ( Tae Hyo Kim ),장현정 ( Hyun Jeong Jang ),김완수 ( Wan Soo Kim ),황재진 ( Jae Jin Hwang ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ) 대한내과학회 2011 대한내과학회지 Vol.81 No.4
유건종은 근초나 근건막 연조직에서 유래하는 양성 섬유종증으로 매우 드물다. 원인은 밝혀지지 않았으나 수술을 포함한 외상, 에스트로겐, 유전적 결함 등이 관여한다고 알려져 있다. 저자들은 진행성 위암으로 인한 전위절제술 이후 복강 내 종괴가 발생하여 시행한 수술에서 유건종으로 진단되었으나 제거치 못하고 경과관찰 중 자연소실을 경험하였기에 문헌고찰과 함께 보고한다. Desmoid tumor is rare neoplasm characterized by clonal proliferation of myofibroblasts that do not metastasise, but often exhibit an infiltrative pattern and functional impairment. The etiology of this tumor is unknown, but hormonal, genetic, and physical factors play a role in its development and growth. The clinical behavior and natural history of desmoid tumors remains unpredictable and enigmatic. However, spontaneous regression of desmoid tumors is rare. Here we report spontaneous regression of an intraabdominal desmoid tumor in a patient who underwent total gastrectomy. (Korean J Med 2011;81:487-491)
다발성 전이를 동반한 후복막강 악성 혈관주위상피모양세포종양
오혜원 ( Hye Won Oh ),김태효 ( Tae Hyo Kim ),차라리 ( Ra Ri Cha ),김나영 ( Na Young Kim ),김현진 ( Hyun Jin Kim ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ),이정희 ( Jeong Hee Lee ) 대한소화기학회 2014 대한소화기학회지 Vol.64 No.5
Perivascular epithelioid cell tumors (PEComas) are unusual mesenchymal neoplasms composed of histologically and immunohistochemically distinct perivascular epithelioid cells (PECs). Although PEComas have the potential to behave in a malignant fashion, malignant PEComas arising from the retroperitoneum are extremely rare. A 68-year-old woman presented with a painful palpable mass in her left upper abdomen. Computed tomography of the abdomen showed a 9 cm sized heterogeneous mass in left para-aortic space and multiple hypervascular nodules in the liver. 18F-fludeoxyglucose-PET/CT showed multifocal hypermetabolic lesions in retroperitoneum, liver, and skeletal bones. Percutaneous needle biopsies were done on the retroperitoneal and hepatic mass. Both specimens were positive for human melanoma black-45 (HMB-45) on histological and immunohistochemical staining which was compatible with PEComas. Herein, we report a rare case of retroperitoneal PEComa with multiple metastases involving liver and bone at initial diagnosis that exhibited aggressive behavior and resulted in a devastating prognosis. (Korean J Gastroenterol 2014,64:302-306)
금식시 흰쥐 소장 점막 유당분해효소에 대한 갑상선 호르몬의 영향 및 이의 유전적 조절 기전
이국래(Kook Lae Lee),이동호(Dong Ho Lee),이한주(Han Ju Lee),윤정환(Jung Hwan Yoon),김재규(Jae Gyu Kim),정운태(Woon Tae Jeong),정현채(Hyun Chae Jung),송인성(In Sung Song),김정룡(Chung Yong Kim) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.6
N/A Background/Aims: We perforrned this experiment to investigate the effect of thyroid hormone on the ]actase activity of rat small intestine by observing the change of lactase level according to the application of thyroid hormon: during fasting. Methods: Forty five male Wistar rats weighing about 260 gram were divided into three groups. The rats of control group(n=5) were sacrificed at 0 hour. The rats of first group(n=20) were starvated with intraperitoneal injection of 0.01 M NaOH 0.1 cc/100 gm body weight daily. The rats of second group(n=20) were starvated with intraperitonea] injection of triicdothyronine(T3) 30 ug disso]ved in 0.01 M NaOH 0.1 cc/100 gm body weight daily. The rats of first and second group were sacrificed at 12 hour, 1 day, 3 day, 5 day respectively, After sacriticing we measured T3 and free T4 level in serum, and intestinal lactase activity from three equally divided segments of removed small intestine. Ancl lactase mRNA were also measured. Results: The T3 and free T4 levels decreased in the NaOH injected groups, especially 3 day or 5 day groups, and T3 level increased in all the thyroid horrnone injected poups but free T4 level decreased. Lactase activity of proxima! Intestine was elevated with fasting, but not elevated in T3 application group. Lactase activity of middle and distal intestine showed similar changes. There was no statistically significant corre1ation between lactase activity and rnRNA level. Con< lusions: Lactase activity is controlled by thyroid hormone. Lactase expression may be regulated at the posttranscription level. (Korean J Gastroenterol 1996; 28:7S7-797)
위암 조직에서 Helicobacter Pylori 검출에 대한 연구
이진호(Jin Ho Lee),전수영(Su Yung Jeon),함희용(Hee Yong Hahm),윤진일(Jin Il Yoon),황성보(Sung Bo Whang),정운태(Woon Tae Jeong),신원창(Won Chang Shin),김관엽(Kwan Yop Kim) 대한내과학회 1993 대한내과학회지 Vol.45 No.2
N/A Background: Helicobacter pylori infection is closely associated with chronic active gastritis and peptic ulcer. Recently, presence of H. pylori in gastric mucosa could play a role in the pathogenesis of gastric cancer. Method: We compared the positivity of CLO test between 41 cases of gastric cancer group and 54 cases of normal control group according to age and sex. Results: 1) There was no difference between positivity and negativity according to age and sex. 2) Total concordance rate of CLO test on the normal tissue was 73.2% in the gastric cancer group, 83.3% in the normal control group, according to the distribution in the stomach. There was no significant difference between the two groups. 3) Concordance rate between cancer tissue and surrounding normal tissue was 91.6% in upper stomach cancer and 75.8% in lower stomach cancer, total concordance rate was 80.5%. 4) Total concordance rate between cancer tissue and whole stomach was 73.2%. Conclusion: Our results suggest that Helicobacter pylori could play a significant role in the development of gastric cancer.
내시경적 역행성담도조영술의 담낭천공에 대한 진단적 가치
이진호(Jin Ho Lee),함희용(Hee Yong Hahm),전수영(Soo Young Jeon),최원충(Won Choong Choi),신원창(Won Chang Shin),정운태(Woon Tae Jeong),김관엽(Kwan Yeob Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.6
N/A The gallbladder perforation was found in patients of cholecystitis with alarmingly high mortality rate. These high morbidity and mortality rates were caused by the delay in diagnosis. Therefore early dianosis and early operative intervention can decrease the confirmatively by demonstration of extravasated contrast media from the lumen of the gallbladder into loculated spaces around it. The purposes of our study are to review the clinical manifestations and values of endoscopic retrograde cholangiography in diagnosis of perforation of the gallbladder.
스테로이드 저항성 궤양성 대장염 환자에 대한 Cyclosporine A의 치료 효과
이대희(Dae Hee Lee),이준행(Jun Haeng Lee),박동영(Dong Young Park),김윤준(Yoon Jun Kim),황진혁(Jin Hyok Hwang),차성덕(Sung Duk Cha),정운태(Woon Tae Jeong),윤정환(Jung Hwan Yoon),이국래(Kook Lae Lee),이동호(Dong Ho Lee),정현채(Hyun Cha 대한소화기학회 1998 대한소화기학회지 Vol.30 No.1
N/A Background/Aims: In refractory severe ulcerative colitis patients who are resistant to intravenous corticosteroids and total parenteral nutrition, new medical therapeutic tools that induce rapid remission is required in order that the patients can avoid colectomy. Since 1990, several western groups reported in their well designed studies that cyclosporine A cou)d induce rapid remission at steroid resistant severe ulcerative colitis patients resulting avoidance of colectomy. We tested the effectiveness of intravenous cyclosporine A therapy at steroid resistant severe ulcerative colitis patients in Korea, which has little experiences in the management of steroid resistant severe ulcerative colitis. Methods: Seven patients were included who were refractory to intravenous corticosteroids and total parenteral nutrition of at least 4 weeks duration. Their liver function tests and creatinine clearance tests were all normal. Cyclosporine A were administered by continuous intravenous methods over 6 hours or 24 hours. The starting doses of cyclosporine A were 4 mg/kg. The blood level was monitored by radioimmunoassay with a monoclonal antibody. The doses were adjusted at blood level from 100 ng/ml to 400ng/ml. In one patient cyclosporine A was administered for only 4 days because of rapid aggravation and consequent emergency operation. In another 6 patients cyclosporine A were administered for 14 days. Results: Four patients revealed scores of less than 10 by clinical activity scores system. But, in spite of improvement by scores, 3 patients of above 4 responders exhibited persistent gross hematochezias at frequencies of more than 3 times a day. Therefore operations were recommended in 6 patients. But one patient refused operation and is under OPD follow up with oral cyclosporine A and corticosteroids medications but he exhibits persistent gross hematochezia at a frequency of 3 or 4 tirnes a day. Out of 5 patients who were operated, 4 patients were cured by operations but 1 patient died because of postoperational sepsis. Conclusions: We found that the intravenous cyclosporine A therapy produced some improvement by clinical activity scores in 4 patients out of 7 patients but induced clinical remission of gross hematochezia in only 1 patient. Therefore operation could be avoided in only 1 patient. This result suggests that the response of Korean patients to intravenous cyclosporine A therapy would be different from that of western people. However, many another studies, especially case control studies are required to clarify this possibility and to assign the proper role of intravenous cyclosporine A therapy in the manageent of patients with ulcerative colitis in Korea. (Korean J Gastroenterol 1997; 30:58-65)