麻黃附子湯이 Papain으로 유도된 골관절염 생쥐 모델에 미치는 영향

장효길,허동석 한방재활의학과학회 2012 한방재활의학과학회지 Vol.22 No.4

Objectives :This study was to investigate the anti-osteoarthritic effects of Mahwangbuja-tang(Mahuangfuzi-tang, MBT) on the papain-induced osteoarthritis. Methods :Arthritis was induced by injection of papain into knee joints of rats. Arthritic rats were divided into four groups(Normal, control, JoinsⓇ, MBT). Control group was taken distilled water for 4 weeks and the MBT group, extracts of MBT by orally for 4 weeks. At the end of the experiment(5 weeks after papain injection), micro CT arthrography and histopathological examinations on the articular structures of knee joint were performed. The effect on inflammatory cytokine, immunological cell in synovial fluid was measured. Gene expressions of inflammatory cytokine in synovial fluid were measured by PCR. Volume of cartilage was measured by micro CT arthrography. Injury of synovial tissue was measured by H&E, safranin-O imunofluorescence. Results :1. IL-6, MCP-1, TNF-α were decreased significantly and IL-1β was decreased in MBT group. 2. Thromboxane B2, Leukotriene B4, prostaglandin E2 were decreased significantly in MBT group. 3. Neutrophil was decreased significantly and white blood cell, monocyte was decreased in MBT group. 4. IL-1β mRNA, iNOS-Ⅱ mRNA were decreased significantly and IL-6 mRNA, TNF-α mRNA, COX-2 mRNA were decreased in MBT group . 5. Through micro CT arthrography, volume of cartilage was increased significantly in MBT group. 6. Histopathologically, injury on synovial membrane of MBT group was decreased and proteoglycan content of MBT group was increased. Conclusions :According to this study, Mahwangbuja-tang has inhibiting effect on the progression of arthritis in papain-induced osteoarthritis model. And it is related to inhibiting the activity of inflammatory cytokine and its gene expression in osteoarthritic chondrocytes and injury of volume in cartilage.

거머리 요법에 대한 연구동향

장효길,허동석,Jang, Hyo-Kil,Heo, Dong-Seok 대한약침학회 2010 Journal of pharmacopuncture Vol.13 No.1

Objective : To review the trend of the study related to Leech therapy and to establish the hereafter direction for the study on Leech therapy. Methods : I reviewed and analyzed all the theses published in Domestic and Foreign research institution from 1990 to 2009. Results : The following results were obtained in this study. 1. Analyzed number of theses published, there was no significance per year. 2. Classified by theme of journal, journals related to surgery were most(41 journals, 75.92%) among 54 kinds. 3. Classified by theses by research method and thesis types, case report accounted for nearly twothirds (52 pieces, 68.42%) of all theses and consideration of document was next(9 pieces, 11.84%). 4. With the most case of venous congestion after plastic and reconstructive surgery(33 pieces, 63.46%), leech therapy was effective on illnesses such as haematoma, macroglossia, purpura, varicous vein, avulsion injury, neurovascular compression, diabetic neuropathy, penoscrotal oedema, buerger's disease, rheumatoid arthritis. 5. Two most appeared adverse effects were anemia and infection. Immediate blood transfusion was done for recovering anemia and prophylactic 3rd generation antibiotics to infection were emphasized in more than half of case reports. 6. All of consideration of documents was retrospective study of cases related leech therapy and 3 pieces of them emphasized prophyratic antibiotic treatment for preventing infection. 7. The study of clinical trail type started first in 2002 and osteoarthritis of knee and carpometacarpal joint were main target. As see above result, Leech therapy was effective cure and could be used in disease induced by venous congestion. And I think that it is necessary to perform additional study related to solution of problems about leech therapy and protocol for using in clinical practice.

우수한 공통 모드 노이즈 특성을 가진 브릿지 다이오드가 없는 고효율 PFC 컨버터

장효서(Hyo-Seo Jang),이주영(Ju-Young Lee),김문영(Moon-Young Kim),강정일(Jeong-Il Kang),한상규(Sang-Kyoo Han) 전력전자학회 2021 전력전자학술대회 논문집 Vol.2021 No.7

试论明清时期汉语语音近三百年的演变 ―以≪翻译老乞大≫,≪重刊老乞大谚解≫右音为例―

장효만,안말숙 동양한문학회 2013 동양한문학연구 Vol.36 No.-

The Ming and Qing Dynasties are the late period of modern Chinese development. With great changes in speech sound and many hot issues for academic research, it is an important transition phase from modern Chinese to contemporary Chinese. Therefore, the phonetic study in Ming and Qing Dynasties has become one of the research focuses for Chinese phonology study. Based on Lao Qi Da, a Chinese textbook used in Cho-Sun Dynasty of Korea, the paper discusses the Chinese phonetic evolution in three hundred years(1515~1795) during the Ming and Qing Dynasties by comparing the right annotated pronunciations in Lao Qi Da(1515) and Nokeoltae Eonhae(1795). 명청시대는 근대 중국어에서 현대 중국어로 넘어가는 중요한 과도기로 어음연구에 있어서 커다란 변화를 가져옴과 동시에 학술적으로도 관심을 많이 받기도 하였다. 명청시대 어음연구는 음운학 연구의 주관심 분야 중의 하나이다. 본고에서는 한국 조선시대의 중국어학습 교재인 『老乞大』를 사례로, 1515년에 편찬된 『飜譯老乞大』와 1795년에 편찬된 『重刊老乞大谚解』 두 저서의 우음(右音)에 대한 비교분석을 통하여 명청시대 즉 1515년에서 1795년까지 근 300년 동안의 중국어어음의 변천에 대해 고찰하고자 한다.

브릿지 다이오드가 없는 고효율 준공진형 PFC 컨버터

장효서(Hyo-Seo Jang),이주영(Ju-Young Lee),한상규(Sang-Kyoo Han) 전력전자학회 2022 전력전자학술대회 논문집 Vol.2013 No.11

Analysis of the Impact of ESG Performance on Corporate Value -A Case of China Mengniu Dairy Company Limited

장효리 인문사회 21 2023 인문사회 21 Vol.14 No.3

Using Mengniu as a case study, this research aims to explore the impact of ESG performance on corporate value from the perspective of Altman-Z model and Tobin’s Q value. This study mainly adopts the literature research method and case analysis method. Firstly, the domestic and international literature on ESG is combed. Secondly, the rating performance and practices of the case company Mengniu regarding ESG management are introduced. Finally, the impact of its ESG performance on corporate value in terms of both book value and market value is analysed, and conclusions are drawn. The comprehensive analysis concludes that improving ESG ratings has a positive effect on both book value and market value of enterprises, affecting corporate value to a certain extent. Companies should focus on improving their ESG ratings and performance to enhance corporate value by strengthening environmental protection, social responsibility and good governance.

面向韩国学生的汉字教学探析

장효만 동양한문학회 2015 동양한문학연구 Vol.40 No.-

The integration of form, pronunciation and meaning of Chinese character and the feature of taking character as the basic structural unit of Chinese language determine the particularity of Chinese character teaching. Guided by the character-based teaching theory and following the features and rules of Chinese characters, this paper analyzes the Chinese character teaching based on the difficulty and emphasis in Chinese character learning for Korean students in Chinese character cultural circle and suggests the opening of an independent Chinese character course in order to better meet the need of Chinese teaching. 한국의 한어교육에서 한자교육의 어려움은 주지하고 있는 바이다. 그 원인의 하나는 복잡하고 어려운 한자의 특징과, 부속적인 형태로 존재한 한자교육이 오랫동안 충분한 중시를 받지 못한데 있다. 한어교육의 발전에 따라 학자들은 차츰 문제의 엄중성을 인식하고 한자교육에 중시를 돌리고 있다. 한자는 형태, 소리, 뜻을 동시에 나타내며, 또한 글자를 기본단위로 하여 구성되어 있는 특징을 지니고 있다. 이런 특징은 한자교육이 특수성을 띠게 한다. 본고에서는 “자본위(字本位)” 교육이론을 바탕으로 한자문화권 한국학습자들의 한자학습 난이도에 근거하여 한자교육의 현황을 조사하고 한자교육의 새로운 방법에 대해 탐구하였으며, 한자교육방법과 교과과정설치 그리고 교재편찬에 대해 건설적인 방안을 제시하고 독립적인 한자과목을 개설할 것을 건의하였다. 이는 한어교육의 활성화에 일조를 할 것이다.

아화운여위해방언어법초탐

장효만 한국중어중문학회 2002 中語中文學 Vol.31 No.-

《四聲通解》聲母系統硏究

張曉曼(Zhang Xiao-Man) 대한중국학회 2003 중국학 Vol.21 No.-

試論崔世珍《動靜字音》中的音變構詞

장효만 ( Xiao Man Zhang ) 中國語文硏究會 2006 中國語文論叢 Vol.0 No.31