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Gore - Tex(TM) membrane 과 COLLACOTE(R) 를 이용한 골유도 재생술의 조직학적 비교 연구
장창덕(Chang Dug Jang),김태규(Tae Kyu Kim),김철훈(Cheol Hun Kim) 대한악안면성형재건외과학회 1997 Maxillofacial Plastic Reconstructive Surgery Vol.19 No.1
The principle of guided tissue regeneration (GTR), as applied to bone healing is based on the prevention of connective tissue from entering the bony defect during the healing phase. This allows the slower bone producing cells to migrate into and reproduce bone within the defect. GTR has demonstrated a level of success in regenerating bone defect. Several types of membrane barrier have been utilized to apply this principle in bone regeneration, The purpose of this study was to evaluate whether improved bone regeneration can be achieved with different membrane barriers (Gore-TexTM membrane, COLLACOTER). In the 10 NewZealand white rabbits, full-thickness bone defects on three sites of each rabbit calvaria were made. Experimental group 1 was covered with COLLACOTER, and group 2 was covered with Core-Tex TM membrane. Macroscopic, microscopic examinations were made serially on 1, 2, 3, 6, 12 weeks after operation. The results were as follows : 1. Macroscopically, both of experimental group 1, 2 were filled with bone-like mass but the defects of experimental group 1 disclosed markedly thinner than the original bone. 2. Microscopically, the defect of experimental group 1, 2 was filled with bony trabeculae without-infection and adverse reaction. But multinucleated giant cell infiltration around COLLACOTER was seen till 6th week. 3. Resorption of COLLACOTER started from 3rd week and it was completely resorped on the 12th week.
장창덕(Chang Deok Jang)(張昌德),윤영호(Yong Ho Yoon)(尹永鎬),전계원(Kye Won Jun)(全桂元) 위기관리 이론과 실천 2011 Crisisonomy Vol.7 No.6
최근 기후변화에 따른 집중호우로 토석류의 발생빈도가 증가하고 있으며 토석류의 발생은 하류지역에 인명과 재산피해를 가져오며 산지하천으로 유입되어 통수단면적의 감소와 같은 2차적인 피해를 가져온다. 토석류는 산지지역의 이용을 위한 개발과정, 산악지도로의 안전성 및 하천으로 유입하는 토사의 유입을 고려하는 전문가들에게 관심의 대상이 되고 있다. 따라서 세계 각 국의 많은 토석류 연구자들은 토석류 위험지역의 분석과 피해의 저감을 위해 다양한 방법으로 연구를 진행하고 있지만 토석류의 복잡성과 다양성으로 인해 연구에 많은 어려움을 겪고 있는 실정이다. 본 연구에서는 토석류 수치해석프로그램 중에 침식과 퇴적작용의 반영이 가능하며 모의수행의 편리한 장점이 있는 Kanako-1D를 이용하여 제천의 토석류 발생지역에 적용하고 현장조사를 통한 토석류발생량과 비교하였다. 그 결과 Kanako-1D로 모의된 양은 LiDAR와 수치지도를 활용해 얻은 토석류유출량에 약 71%인 6,953m3 로 평가되었다. Recently because of severe rain storm arising from the climate change, frequency of debris flow is increasing. Occurrence of debris flow causes huge losses of life and property in downstream areas. Also sediment formed by occurrence of debris flow is supplied into mountainous river, which causes the secondary damage such as reduction of cross-sectional area or blocking access routes to the disaster areas. Debris flow is attracting much interest of specialists considering the development process for the use of mountainous area, safety of mountainous road and inflow of earth and sand flowing into the river channel. Therefore debris flow researchers in the world are conducting study in many ways for analysis of debris flow hazard areas and damage reduction. But they have a lot of difficulty studying because of complexity and diversity of debris flow. In this study, Kanako-1D was used among debris flow numerical analysis softwares. And Kanako-1D can reflect erosion and sedimentation and has advantage of convenience for simulation. By using Kanako-1D, the program was applied to the debris flow areas in Jecheon and was compared with debris flow production through field investigation. According to the result, the amount simulated by Kanako-1D was 6,953m3, 71% of debris flow discharge gained by using LiDAR and 1:5000 numerical map.