가미자운고(加味紫雲膏)가 mouse의 피부화상 치료에 대한 분자생물학적 효과 및 기전연구

이종철,김경준,Lee, Jong-Chul,Kim, Gyung-Jun 대한한방안이비인후피부과학회 2015 한방안이비인후피부과학회지 Vol.28 No.1

Objective: The aim of this study was to investigate the wound healing effect of herbal ointment, Gamijaungo, on the burn-induced model. Reports about Gamijaungo on the wound healing effect by local application in mice model or human study have published in the several domestic or internationally, but most are anecdotal and lack solid scientific evidence. Method: We observed the morphologic and histologic changes in the burn-induced mice model. we counted white blood cell and platelet changes. we confirmed VEGF, PI3K and pAkt protein expression by Western blot analysis. Result: In this study, we observed that Gamijaungo showed strong wound healing effects in the morphologic and histologic changes in the burn-induced mice model. Also we found that the significant changes of white blood cell and platelet changes by the treatment of Gamijaungo. In molecular mechanism, we got the strong positive effect by Gamijaungo treatment on angiogenesis, a key process in the formation of the granulation tissue during wound healing. Conclusion: These findings suggest the potential use of Gamijaungo as a therapeutic in thermal burn-induced skin injuries.

벼담수 직파 재배에서 파종 입수가 생육 및 수량에 미치는 영향

이종철,문창식,서해영,최범열,Jong-Chul Lee,Chang-Sik Moon,Hae-Yeong Suh,Beom-Yeol Choi 한국작물학회 1973 한국작물학회지 Vol.- No.14

본 시험은 중부지방에서 담수직파재배에 알맞은 파종립수를 구명함과 파종립수에 EK른 수량 및 수량구성요소의 변이를 알고져 1972년에 수행하였던 바 그 결과를 요약하면 다음과 같다. 1. 최고분얼수는 밀파할수록 직선적으로 증가하여 280립 파종구에서 최고수치를 보였고 그 이후는 점차 감소되었으며 분얼에 대한 경합은 $m_2$당 280립이상 파종구에서 뚜렸했다. 2. 유효경비율은 $m_2$당 120립부터 280립 파종구까지는 파종밀도가 증가될수록 감소되다가 그 이후는 점차 증가되었다. 3. 최고분얼수가 $m_2$당 1,000개 이하에서는 얼자간 경합이 적었다. 4. 수수와 파종립수는 현저한정(+)의 상관이 인정되었고 수수와 일수영화수, 수수와 동숙비율은 (-)의 상관 경향이었다. 5. 수량과 $m_2$당 영화수는 r=0.929이며 수량과 수수는 r=0.695, 수수와 $m_2$당 영화수는 r=0.796이었다. 또한 수량과 수량구성요소간의 순위상관을 보면 수량과 수수가 가장 상관이 높았으며 (r=0.954_ 담수직파에서 수량을 지배하는 요인은 수수이었다. 6. 수량은 $m_2$당 280립 파종구에서 최고를 나타냈다. This study was carried out in the central part of Korea in 1972 to investigate optimum grain number per square meter and variation of the yield and its components in the direct sowing culture on irrigated paddy field. The results could be summarized as follows; 1. Number of maximum tillerings was directly increased with increase of grain number from 120 to 280 per square meter and it was gradually decreased with increase of number sowing grain. So number of maximum tillerings showed at the plot of 280 grain per square meter. Also it was showed remarkable competition at the plot more than 280 grain per square meter. 2. Percentage of effective tiller was decreased with increase of number of sowing grain from 120 to 280 per square meter and after it was gradually decreased with increase of number of sowing grain. 3. It was not remarkable competition in plot less than 1, 000 tillering per square meter on the number of maximum tillerings. 4. It was remarkable positive correlation between the number of panicle and the number of sowing grain, but it was tendency to negative correlation between the number of panicle and the number of spiklets per panicle, and between the number of panicle and the ripening ratio. 5. Correlation coefficient between the yield and the number of spiklet per square meter of land area was 0.929, r=0.695 in the yield and the number of panicle, r=0.796 in the number of panicles and the number of spiklets per square meter Also in rank correlation, it was showed most highly positive correlation(r=0.954) between the yield and the number of panicles, so number of panicles was most largely dominated on yield among the yield components in direct sowing culture on irrigated paddy field. 6. It was producted highest yield in the plot of 280 grain sowing per square meter.

대황(大黃)의 Elastase 활성 억제와 Tyrosinase 억제연구

이종철,김경준,Lee, Jong-Chul,Kim, Kyung-Jun 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.3

Objective : Recently, the demands for the effective and safe depigmentating and anti-aging agents of the skin have increased due to the medical, pharmaceutical and cosmetic reasons. The aim of this study is to search new materials from the traditional herbal medicines which inhibit the aging process of skin in vitro. Methods : herbal medicines(80% ethanol or water extracts) were screened for their inhibitory activities against elastase. Results : Rheum undulatum (final concentrstion 1 mg/ml) appeared over 30% of inhibition of elastase activity. so we are investigated anti wrinkle effects of Rheum undulatum look through MMP-1 inhibition activity. also Extracts of Rheum undulatum showed higher anti tyrosinase activity than arbutin (final concentration 1 mg/ml). Conclusion : These results suggest that herbal medicines could be strong potential sources of inhibition of anti-aging and whitening effects for the skin.

Cu₂In₃, CuGa, Cu₂Se를 이용한 전구체박막을 셀렌화하여 제조한 Cu(In,Ga)Se₂ 박막의 미세구조 및 농도분포 변화

이종철,정광선,안병태,Lee, Jong-Chul,Jung, Gwang-Sun,Ahn, Byung-Tae 한국재료학회 2011 한국재료학회지 Vol.21 No.10

A high-quality CIGS film with a selenization process needs to be developed for low-cost and large-scale production. In this study, we used $Cu_2In_3$, CuGa and $Cu_2Se$ sputter targets for the deposition of a precursor. The precursor deposited by sputtering was selenized in Se vapor. The precursor layer deposited by the co-sputtering of $Cu_2In_3$, CuGa and $Cu_2Se$ showed a uniform distribution of Cu, In, Ga, and Se throughout the layer with Cu, In, CuIn, CuGa and $Cu_2Se$ phases. After selenization at $550^{\circ}C$ for 30 min, the CIGS film showed a double-layer microstructure with a large-grained top layer and a small-grained bottom layer. In the AES depth profile, In was found to have accumulated near the surface while Cu had accumulated in the middle of the CIGS film. By adding a Cu-In-Ga interlayer between the co-sputtered precursor layer and the Mo film and adding a thin $Cu_2Se$ layer onto the co-sputtered precursor layer, large CIGS grains throughout the film were produced. However, the Cu accumulated in the middle of CIGS film in this case as well. By supplying In, Ga and Se to the CIGS film, a uniform distribution of Cu, In, Ga and Se was achieved in the middle of the CIGS film.

산지(産地) 반양직묘포(半養直苗圃)에서의 묘삼수량(苗蔘收量)과 토양이화학성간(土壤理化學性間)의 관계조사(關係調査)

이종철,변정수,안대진,Lee, Jong-Chul,Byen, Jeong-Su,Ahn, Dai-Jin 한국토양비료학회 1988 한국토양비료학회지 Vol.21 No.2

산지(産地) 반양직묘포(半養直苗圃)(활엽수(闊葉樹)를 많이 넣고 여러번 경운(耕耘)한 밭흙을 곱게 쳐서 만든 묘포(苗圃)) 29개포장(個圃場)에서 묘포토양(苗圃土壤) 이화학성(理化學性)과 묘삼수량(苗蔘收量)과의 관계룰 조사한 결과(結果)는 다음과 같다. 1. 사용가능묘삼생산량(使用可能苗蔘生産量)은 간(間)($90{\times}180cm$) 당(當) $362{\pm}226$본(本)이었다. 2. 세사(細砂)+극세사(極細砂)의 함량(含量)이 많을수록 묘삼개체근중(苗蔘個體根重)이 감소(減少)되었다. 3. 묘포토양내(苗圃土壤內)에서 pH는 OM, K, Ca 및 Mg와, EC는 Ca, Mg 및 N와 각각(各各) 정상관(正相關)이 있었다. 4. 묘삼개체중(苗蔘個體重)은 토양내(土壤內) pH 상승(上昇)과 OM, K, Ca 및 $P_2O_5$ 함량(含量)이 많을수록 증가(增加)되나 N과는 상관(相關)이 없었다. 5. 토양내(土壤內)에 $P_2O_5$, K 및 Ca 함량(含量)이 많을수록 묘삼근내(苗蔘根內) 함량(含量)이 증가(增加)되었다. 6. 근내(根內)의 $P_2O_5$, K의 흡수(吸收)가 증가(增加)될수록 묘삼개체근중(苗蔘個體根重)이 증가(增加)되었다. To get the basic information about ginseng seedling production, yield of ginseng seedling and soil physico-chemical components of Ban-Yang-Jik (semimodified soil) nursery in 29 farmer's field were investigated. The number of available seedling per Kan (Kan means $180{\times}90cm$ area) is $362{\pm}226$. Root weight per seedling was negatively correlated with ammount of fine and extremely fine sand. Positive correlations were shown between pH and OM, K, Ca and Mg, and also between EC and Ca, Mg and ammonium and nitrate nitrogen in soil of nursery. There were significant linear relations between root weight and OM, K, Ca and Mg in soil of nursery. On the other hand, quadratic relation was held between the root weight and $P_2O_5$, but the root weight has no correlation with nitrogen. The nitrogen contents of soil might not influence on the growth of ginseng seedling as greatly as those of $P_2O_5$, K and Ca. The contents of $P_2O_5$, K and Ca in root were increased with increase of the contents of $P_2O_5$, K and Ca in soil of nusery, respectively. It showed the linear correlation between the root weight and $P_2O_5$ and Ca, otherwise quadratic correlation between the root weight and K in root.

회원작품 - 수원 인계동 빌딩

이종철,Lee, Jong-Chul 대한건축사협회 1998 建築士 Vol.1998 No.8

수도의 영화수성립과 수량에 미치는 기상환경의 영향에 관한 연구 II. 영화수 성립에 미치는 기상소모효과

이종철,안수봉,Lee, Jong-Chul,Ahn, Su-Bong 한국작물학회 1984 한국작물학회지 Vol.29 No.4

In order to confirm the effect of climatic consumption index (C C I) on the number of spikelets and yield of rice, 3 levels of shading rates such as 0, 25, 50% of full light were treated during the tillering stage, reproductive growth stage and ripening period, respectively, in a phytotron controlled with day/ night temperature of 20/10$^{\circ}C$ and 30/20$^{\circ}C$, and field at Crop Experiment Station, Suwon, Korea. The results are as follows: 1. As solar radiation decreased during the reproductive growth stage in 30/20$^{\circ}C$ or field condition, the number of spikelets per panicle was decreased due to the decrease of the number of differentiated secondary rachis branches and spikelets as well as the increase of the number of degenerated secondary rachis branches and spikelets. 2. Our results showed slight negative correlation between C C I of the reproductive growth stage and number of panicles per square meter and number of differentiated secondary rachis branches. On the other hand, there was highly significant positive correlation between C C I of the reproductive growth stage and the number of degenerated secondary rachis branches and spikelets, and negative correlation in number of differentiated spikelets. 3. The shading during the reproductive growth stage did not affect on the percentage of ripened grains and 1000 grains weight of hulled rice, whereas those were decreased with shading during the ripened period. 4. Influence of shading in each growing stage on the yield was severe in the order of ripened period, reproductive growth stage, tillering stage. 5. Respiration rate in Jinheung was higher than that of Tongil at low temperature, but reversed above 30$^{\circ}C$. Respiratory coefficients (Q$\sub$10/) of Tongil and Jinheung were 2.74 and 1.96, respectively. Respiration/ photosynthesis ratio in Jinheung was higher than that of Tongil at low temperature, while higher in Tongil above 32$^{\circ}C$. 6. Transportation of $\^$14/C was restricted at 20/10$^{\circ}C$ in Tongil, however, there was no differences at 30/20$^{\circ}C$ in both Tongil and Jinheung. The influence of shading on the transportation of $\^$14/C did not affect at 20/10$^{\circ}C$, but it was hampered with shading at 30/20$^{\circ}C$ in both varieties.

석회암 지대 참나무속 식물에 공생하는 외생균근균의 군집구조

이종철 ( Jong-chul Lee ),박혁 ( Hyeok Park ),엄안흠 ( Ahn-heum Eom ) 한국균학회 2021 韓國菌學會誌 Vol.49 No.1

국내 석회암지대에 서식하는 참나무류의 뿌리에서 외생균근균(ectomycorrhizal fungi, ECM)의 다양성을 분석하였다. 분자분석을 통해 참나무류에 공생하고 있는 45속의 ECM을 확인하였다. ECM의 종 다양성 지수는 pH, 칼슘 농도, 유효인산 농도가 증가할수록 감소하는 경향을 보였고, 전질소 함량과 유기물 함량이 증가할수록 증가하는 경향을 보였다. 군집분석 결과 석회토양의 특징인 pH와 칼슘 농도와 양의 상관관계를 갖는 ECM은Sebacina, Tomentella, Tuber, Densospora, Inocybe, Suillus, Piloderma속에 속하는 균주들 이였으며, 이들은 토양 안정성이 약화된 석회암지대의 생태복원에 활용될 수 있을 것으로 판단된다. In this study, we analyzed the diversity of ectomycorrhizal (ECM) fungal communities of Quercus spp. roots in the limestone area. We identified 45 generd of ECM using next generation sequencing (NGS) analysis. Soil chemical composition analysis confirmed soil pH, substitution calcium concentration, total nitrogen content, organic phosphate, and organic matter content. Shannon’s Index was calculated according to the changes in soil chemical composition. The results of cluster analysis showed that Sebacina, Tomentella, Tuber, Densospora, Inocybe, Suillus, and Piloderma were the main genera of symbiotic ECM fungi that thrived in soil with high pH and calcium content.

가스차단기의 소전류 차단성능 향상을 위한 유동해석

이종철(Jong-Chul Lee),최종웅(Jongung Choi),강성모(Sung-Mo Kang),김윤제(Youn-Jea Kim) 대한기계학회 2003 대한기계학회 춘추학술대회 Vol.2003 No.4

The flow analysis is needed to verify the physical phenomena through interruption processes for<br/> improving the capacity and the reliability of gas circuit breakers. Moreover the small current interruption<br/> performance of GCBs could be predicted by coupling the flow characteristics with the electric field one. In<br/> this paper, the unsteady flow characteristics and the traveling trajectory are depicted with a commercial CFD<br/> code, PHOENICS, programmed for moving motion of objects. In order to validate computational results, the<br/> measured pressure data in cylinder and in front of arcing contact are compared with the test results of small<br/> current interruption.

열팽창 파퍼식 가스차단기 차단설계를 위한 비정상 아크 플라즈마 유동해석

이종철(Jong-Chul Lee),김윤제(Youn J. Kim) 대한기계학회 2005 대한기계학회 춘추학술대회 Vol.2005 No.5

During the last ten years the new interruption techniques, which use the arc energy itself to increase the pressure inside a chamber by the PTFE nozzle ablation, have displaced the puffer circuit breakers due to reduced driving forces and better maintainability. In this paper, we have investigated the flow characteristics inside a thermal puffer type gas circuit breaker by solving the Navier-Stokes equations coupled with Maxwell's equations for considering all instabilities effects such as turbulence and Lorentz forces by transient arc plasmas. These relative inexpensive computer simulations might help the engineer research and design the new interrupter in order to downscale and uprating the GIS integral.