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RISS 인기검색어
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- 저자 : 이기일(Kee Il Lee) (검색결과 4 건)
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이기일(Kee Il Lee),박율리(Yu Li Park),김현승(Hyun Seung Kim) 대한안과학회 2016 대한안과학회지 Vol.57 No.1
Purpose: To assess the changes in anterior, posterior, and total corneal astigmatism after cataract surgery with on-axis clear corneal incision cataract surgery. Methods: This study included 48 eyes (24 eyes with ‘with-the-rule [WTR]’ and 24 eyes with ‘against-the-rule [ATR]’) that underwent phacoemulsification and intraocular lens insertion through on-axis clear corneal incision. The ATR group with vertically steep axis of posterior corneal astigmatism was divided into subgroups 1 and 2 for the opposite axis. Autorefraction, uncorrected and best-corrected visual acuities were measured. Corneal astigmatism (anterior, posterior and total) was measured using Pentacam?? preoperatively and 1 week, 1 month, and 2 months postoperatively. Results: Multivariate linear regression analysis of preoperative data showed positive correlations among anterior, posterior and total astigmatism. Anterior corneal astigmatism showed a significant decrease in both WTR and ATR groups in all measured points (all p < 0.05). Posterior corneal astigmatism showed no statistical difference in the WTR group and ATR subgroup 2 (p > 0.05) and significant decrease in the ATR subgroup 1 (p < 0.05) at 2 months postoperatively. Total corneal astigmatism showed significant decrease 2 months after surgery in the WTR group and ATR subgroup 1 (all p < 0.05), but not in the ATR subgroup 2(p > 0.05). According to correlation analysis based on trend line equations, 1.7 diopters of anterior astigmatism could expect 0.3 diopters of posterior astigmatism and 0.5 diopters of total astigmatism for the WTR group and 0.4 diopters of anterior astigmatism could expect 0.2 diopters of posterior astigmatism and 0.4 diopters of total astigmatism for the ATR group. Conclusions: Considering the majority of cataract patients have vertically steep posterior corneal astigmatism, temporal incision for ATR patients is generally effective. Moreover, for patients with WTR astigmatism of more than 1.7 diopters or ATR astigmatism greater than 0.8 diopters, additional preoperative correction based on posterior astigmatism is needed for more precise prediction of postoperative total corneal astigmatism.
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녹내장 환자에서 유리체강 내 베바시주맙 주사가 망막신경섬유층에 미치는 영향
박창현,이기일,박혜영,이진해,김인태,박찬기,Chang Hyun Park,Kee Il Lee,Hae Young Park,Jin Hae Lee,In Tae Kim,Chan Kee Park 대한안과학회 2014 대한안과학회지 Vol.55 No.5
Purpose: To examine retinal nerve fiber layer (RNFL) changes after intravitreal injection of bevacizumab in patients with or without underlying glaucoma. Methods: A total of 104 eyes of 104 patients with retinal disease undergoing intravitreal injection of bevacizumab were prospectively investigated. Bevacizumab injections (1.25/0.05 mg/mL) were performed using a standardized technique. In the patient who had pretreatment with intraocular pressure (IOP)-lowering medication, 1 drop of brimonidine was instilled 30 minutes before the injection. Before and after the intravitreal injections, the patients were monitored for IOP and evaluated with optical coherence tomography using Stratus at least 3 months after the injection. Results: Thirty minutes after injection, 6.4% of patients had an IOP over 30 mm Hg in the non-pretreatment group while no patient had an IOP over 30 mm Hg in the pretreatment group. In eyes with only retinal diseases, the RNFL thickness did not change significantly after the injection regardless of pretreatment, whereas in eyes with underlying glaucomatous damage and no pretreatment, significant decrease in RNFL thickness was observed at the superior (<em>p</em> = 0.036) and temporal (<em>p</em> = 0.048) sectors of the optic nerve head without pretreatment. Conclusions: Intravitreal injection of bevacizumab did not typically cause significant changes in RNFL thickness; however, in eyes with underlying glaucoma without pretreatment, a significant decrease in RNFL thickness was observed in the superior and temporal sectors of the optic nerve head. Therefore, applying IOP-lowering pretreatment medication before intravitreal injection of bevacizumab is required for protection of RNFL in glaucoma patients. J Korean Ophthalmol Soc 2014;55(5):693-701
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한국인에서 B 형 간염 바이러스 감염상태와 HLA - DR type 과의 연관성
안상훈(Sang Hoon Ahn),한광협(Kwang Hyub Han),이천균(Chun Kyon Lee),김동기(Dong Kee Kim),강신욱(Shin Wook Kang),전재윤(Chae Yoon Chon),문영명(Young Myoung Moon),박기일(Ki Il Park) 대한내과학회 1998 대한내과학회지 Vol.55 No.1
N/A Objectives : The course after hepatitis B virus infection appears not to be related to variations in virulence of the HBV itself and may be influenced by the host immune response, which in turn may be regulated by the major histocompatibility complex. The purpose of this study was to determine whether the clearance of HBV was related to a particular HI& allele in Korean. Methods : We studied total 1372 Korean persons who had visited Yonsei University Medical Center for renal transplantation from January in 1990 to August in 1997. Hepatitis B-virel markers and HLA-DB types were examined by retrospective study. Results . 1) Among 1372 subjects, 924 were male and 448 were female(Mean age, M:37.4yrs, F:38.3yrs). Healthy donors in total subjects were 424. 2) Commonly, HLA-DR4 was most frequent among the total subjects, also in the group of Non-Exposure, Chronic Carrier, Clearance, and Antibody. 3) HLA-DR6 was significantly frequent in the group of Clearance and Antibody compared with the group of Chronic Carrier(p<0.001, RR=3.72 and p<0.001, RR=3.58, respectively). HLA-DR9 was significantly frequent in the group of Chronic Carrier compared with the group of Clearance and Antibody(p<0.001, BR=3.33 and p<0.001, RB=3.32). Results in healthy donors were same as above. 4) HLA-DR13 was significant between the HLA-DR6 subgroups(DB13, DR14! which may influence the clearance of HRU. Conclusion: HLA-DR6(esp, HLA-DR13) may be associated with elimination of HBV as one of the host factors influencing the immune response to HBV and HLA-DR9 with persistent HBV infection.
KCI
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