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김정수,이건웅,오원태,Kim, Jung-Soo,Lee, Geon-Woong,Oh, Weon-Tae 한국전기전자재료학회 2007 전기전자재료학회논문지 Vol.20 No.10
Carboxylated multi-walled carbon nanotubes (MWNTs) were in detail characterized by XRD, XPS, FTIR, and thermogravimetric measurements. Carboxylic acid groups were functionalized to MWNTs under aqueous acid condition. The changes of sonication and reflux conditions rarely influenced the degree of carboxylation on MWNTs, but decreased the thermal stability of the resultant carboxylated MWNTs. XRD results showed that the diffraction peaks (100), (101), and (102) of pristine MWNTs disappeared after acid treatment, but the diffraction peak (002) was Preserved in the carboxylated MWNTs. The introduction of carboxylic acid groups on MWNTs caused to improve the dispersibility of the resultant carboxylated MWNTs in water.
사람 구강편평세포암종 KB 세포 성장억제에 미치는 비방탈명산의 효과
이백희 ( Baek Hee Lee ),이건웅 ( Geon Woong Lee ),김도경 ( Do Kyung Kim ) 조선대학교 치의학연구원 2010 Oral Biology Research (Oral Biol Res) Vol.34 No.2
The Bibangtalmyungsan has been used in Korean traditional medicine as an anti-inflammatory and an analgesic, which is consisted of 12 constituents (Lonicerae Flos, Ledebouriellae Radix, Paeoniate Radix Rubra, Citrinobilis Pericarpium, Rhei Radix et Rhizoma, Fritiliariae Bulbus, Gleditsiae Spina, Angelicae Dahuricae Radix, Glycyrrhizae Radix, Boswellia carteri, Angelicae gigantis Radix and Manitis Squarna). However, the anti-cancer activity of Bibangtalmyungsan has not been well defined yet. In this study, therefore, the cytotoxic activity of each ingredient ethanol extract of Bibangtalmyungsan was examined in KB human oral squamous cell carcinoma. The cytotoxic effect of each ingredient of Bibangtalmyungsan on cell growth in KB cells was examined using MTT assay. The growth of KB cells was not inhibited by each Lonicerae Flos, Ledebouriellae Radix, Paeoniate Radix Rubra, Citrinobilis Pericarpium, Rhei Radix et Rhizoma or Fritiliariae Bulbus treatment for 24 hours. Treatment of Gleditsiae Spina or Angelicae Dahuricae Radix in KB cells induced the cell growth inhibition slightly. The growth of KB cells was completely inhibited by Glycyrrhizae Radix, Boswellia carteri or Angelicae gigantis Radix in a concentration-dependent mainner and the IC50 values for the growth inhibition of KB cells of Glycyrrhizae Radix, Boswellia carteri or Angelicae gigantis Radix treatment were about 494, 189 and 71㎍/ml, respectively. These results suggest that among the 12 constituents of Bibangtalmyungsan Glycyrrhizae Radix, Boswellia carteri and Angelicae gigantis Radix can induce the suppression of cell growth in KB human oral squamous cell carcinoma, and therefore, that they may have potential properties for anti-cancer dreg discovery.
위턱굴 점막(Schneiderion membrane)의 조직형태계측학적 특성
정구수 ( Goo Soo Jeong ),이건웅 ( Geon Woong Lee ),김성훈 ( Seong Hoon Kim ),전현상 ( Hyun Sang Jeon ),국중기 ( Joong Ki Kook ),김흥중 ( Heung Joong Kim ) 조선대학교 치의학연구원 2010 Oral Biology Research (Oral Biol Res) Vol.34 No.2
For dental implant placement on maxilla, both the shape of maxillary sinus and characteristic of sinus membrane are important. Particularly, the sinus graft surgery needs the accurate understanding of maxillary sinus mucosa (Schneiderian membrane). Therefore, the purpose of this study is to investigate the thickness and histologic characteristics of the maxillary sinus mucosa. Six cadaver heads (12 maxillary sinuses) were examined (4 male and 2 female, average age; 55.8 years). The specimens were decalcified with EDTA, embedded with the paraffin and microsectioned to 5㎛ thickness. The sections were stained hematoxylineosin (H&E) and observed by the light microscope (Carl Zeiss, GER). The thickness of sinus membrane measured by the Axiovision LE release 4.6 (Carl Zeiss, GER). The mean thickness of the maxillary sinus mucosa was 369±82.03㎛, and the mean thickness of the nasal cavity mucosa was 881±67.12㎛. The maxillary sinus mucosa was a continuation of the nasal cavity mucosa, its epithelium consisted of pseudostratified ciliated columnar epithelium and the goblet cells were located among the columnar epithelium. The lamina propria of the maxillary sinus mucosa was thinner than the nasal cavity mucosa, which also had relatively fewer glands and vascular distribution. The bony wall of the maxillary sinus adjacent the sinus mucous membrane was mostly continuous, but was scarcely perforated by neurovascular channels. For the sinus graft surgery, it is crucial to understand the anatomic knowledge of the membrane thickness as well as glands distribution and vascular distribution of the maxillary sinus.