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5-FU, Cisplatin 사용 후 발생한 방사선 회상 근염 1예
유양선 ( Yang Seon Ryu ),전찬홍 ( Chan Hong Jeon ) 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.1
Radiation recall phenomenon is an inflammatory reaction which occurs at a previously irradiated area after the administration of causative agents, especially anticancer drugs. Radiation recall mostly involves skin and rarely affects internal organs. We, hereby, report a rare case of radiation recall myositis. A 51-years-old man visited the hospital due to pain and weakness of the left thigh. He had been diagnosed with a skin metastasis of pancreatic adenocarcinoma, at the left thigh and treated with radiotherapy and subsequent combination chemotherapy of 5-FU and cisplatin. After the 5th cycle of chemotherapy, the patient developed pain and weakness localized at the previous radiation field. An MRI revealed myositis of left gluteus medius muscle. Muscle biopsy showed no malignant cells or signs of infection. He was diagnosed as having radiation recall myositis and treated with steroid and NSAID. Soon after, pain and weakness gradually improved. Although rare, a possibility of radiation recall myositis should be considered when a patient with history of radiotherapy has a myopathy.
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윤동주(尹東柱)의 「바람이 불어」에 나타난 자아(自我) 이해(理解)
유양선 ( Ryu Yang-seon ) 한국어문교육연구회 2014 어문연구(語文硏究) Vol.42 No.3
尹東柱는 그의 시 「바람이 불어」(1941.6.2)에서, 倫理的 實存을 넘어 宗敎的 實存으로 跳躍하는 모습을 보여주고 있다. 이 시에서 시인은 主體性을 지닌 윤리적 실존으로서의 자신이 普遍的 倫理를 실현할 수 없다는 것을 告白하며 통절히 뉘우친다. 이 뉘우침 속에 윤리적 실존은 自己矛盾을 드러내며 切望한다. 그러나 이 절망은 새로운 自我를 형성하는 발판이 된다. 시인은 沈默의 祈禱를 통해 무한한 사랑이신 하느님의 말씀을 듣고 진정한 자아를 찾게 되는 것이다. 이렇게 거듭난 자아는 信仰의 決斷을 통해 强化된 새로운 主體性이다. 시인은 마침내 時間 속에서 永遠을 만나는 종교적 실존으로서의 自我를 確立한다. 그리하여 그리스도와의 同時性을 획득하는 바, 이것은 그 자체로 殉敎의 의미를 內包하는 것이다. This essay is an analysis of Yun, Dong-ju’s 「The Wind Is Blowing」, which was written when he was in the first half of graduating class of Yonhee College. In this chapter of his life, within the influence of Kier kegaard's existential philosophy, he established his subjecthood in Christian faith. So, I try to grasp the meaning of leaping from ethical existence to religious existence. 「The Wind Is Blowing」 is largely divided into two parts, the first half being the first to the fourth stanza and latter half being the fifth to the sixth stanza. The first half implies that ethical attitude to life fails when the poetic self sees that he cannot realize the universal. And the latter half portrays the image of religious existence; the poetic self is grounded transparently in God. There is the prayers of the poetic self between ethical existence and religious existence. In the deepest sense prayer is the language of openness, and the language of openness to God is silence. The poetic self comes to realize that true prayer is to wait until he hears the words of God in silence, he becomes conscious of the tremendous gulf between himself and God, finally he accepts himself as a sinner. The fundamental theme of 「The Wind Is Blowing」 is the meaning of personal existence, ultimately, the problem of becoming a Christian. The poetic self-accepts the paradox that God, the Eternal, has become incarnate in a particular individual man, Jesus, in time. Finally, the poet stands where time and eternity meet, in this sense he is contemporary of Christ, and his faith is martyrdom in itself.
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윤동주(尹東柱)의 시(詩)에 나타난 종말의식(終末意識) - 광명중학(光明中學) 시절(時節)의 시편(詩篇)들을 중심(中心)으로 -
유양선 ( Ryu Yang-seon ) 한국어문교육연구회 2016 어문연구(語文硏究) Vol.44 No.1
尹東柱는 日帝가 경영하던 龍井의 光明中學을 다니는 동안, 극도로 타락한 非歷史的 時代를 직접 체험하면서 시를 썼다. 이 시기 그의 시편들은 당시의 시대적 어둠으로 인한 內面的 葛藤의 記錄이다. 그는 歷史 속에서 일하시는 하느님의 役事를 믿으면서, 시대적 어둠에 휩쓸리지 않고 자신의 歷史的 位置를 지키며 깨어 있고자 하였다. 타락한 시대가 주는 좌절감을 終末論的 希望으로 극복해 나아갔던 것이다. 光明中學 시절에 시작된 그의 그리스도교적 終末意識은 그의 시를 형성한 基本動因 중의 하나이다. 그의 終末意識은 이후, 연희전문 시절과 東京 유학 시절을 거치면서 더욱 발전하여, 그로 하여금 암울한 시대를 넘어 마침내 殉敎에까지 나아가도록 한 내면적인 힘의 根源이 된다. While attending Gwangmyeong Middle School of Longjing, operated by the Japanese, Yun, Dong-ju directly experienced an era of ahistorical period which was extremely corrupt. Yun’s poems written during this period reflect his covert conflict caused by the darkness of the time. Yun, as he believed the work of God who worked within the history, tried to maintain his historical position and remain enlightened without being overwhelmed by the darkness of the time. He had overcome the challenges of the corrupted era with apocalyptic hope. Yun’s apocalyptic consciousness of Christianity that had been instilled during his time at Gwangmyeong Middle School is one of the fundamental motives that formed his poems. Yun’s apocalyptic consciousness developed even further in the later days as it had become the source of insidious force which made him overcome the dark times and die a martyr for his faith.
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양미연 ( Mi Yean Yang ),유양선 ( Yang Seon Ryu ),고희자 ( Hee Ja Ko ),박세경 ( Se Kyng Park ),박종숙 ( Jong Sook Park ),박춘식 ( Chun Sik Park ),박재성 ( Jae Sung Park ),백상현 ( Sang Hyen Bak ),고은석 ( Eun Suk Ko ),박정미 ( Jeon 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.69 No.1
Sarcoidosis is a multi-systemic granulomatous disorder of unknown etiology. The characteristic pathological finding is the presence of non-caseating granulomas. The lungs are primarily affected, however other organs may be involved causing various symptoms and ambiguous laboratory findings can be present. There are a few reported cases of sarcoidosis with elevated tumor markers. We describe a 68-year-old woman presenting with sarcoidosis showing elevated serum carcinoembryonic antigen (CEA). The possibility of cancer arising from serum CEA such as gastrointestinal cancer, breast cancer and lung cancer was excluded. A transbronchial lung biopsy demonstrated a non-caseating granuloma without necrosis. As a result prescribed 30 mg prednisolone daily to the patient and serum CEA was decreased after 1 month of treatment. We report a case of pulmonary sarcoidosis with elevated serum CEA.
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사례보고 : 만성 C형간염 환자에서 페그인터페론 알파 2b 치료 중 동시 발생한 당뇨병성 케톤산증과 자가면역 갑상샘염 1예
이윤나 ( Yun Nah Lee ),정승원 ( Soung Won Jeong ),임재희 ( Jae Hee Lim ),유양선 ( Yang Seon Ryu ),전성란 ( Seong Ran Jeon ),김상균 ( Sang Kyun Kim ),장재영 ( Jae Young Jang ),김영석 ( Young Seok Kim ),김부성 ( Boo Sung Kim ),노미 대한간학회 2010 Clinical and Molecular Hepatology(대한간학회지) Vol.16 No.2
Combined pegylated interferon and ribavirin therapy for chronic hepatitis C infection cause a wide range of side effects, including flu-like syndrome, hematological abnormalities, cardiovascular symptoms, gastrointestinal symptoms, pulmonary dysfunction, depression, and retinopathy. Interferon-alpha has been shown to be related to the development of various autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, autoimmune thyroid disease, and type 1 diabetes mellitus (DM). Type 1 DM and thyroid disease respectively develop in 0.08~2.61% and 10~15% of patients treated with combined interferon-alpha and ribavirin for chronic hepatitis C. The coexistence of type 1 DM and autoimmune thyroiditis was rarely reported. We report a case of a 33-year-old female patient with chronic hepatitis C who simultaneously developed diabetic ketoacidosis and autoimmune thyroiditis after treatment with pegylated interferon-alpha 2b and ribavirin.
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