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오인선(In Sun Oh),이소희(So Hee Lee) 한국아동가족복지학회 1997 한국가족복지학 Vol.2 No.1
A qualitive approach was attempted to find out that youth`s information inequality would happen under what structure and what environment differently from adults using a group discussion method according to the subject and cultural technological magazine. The reason of youth`s information inequality can be largely divided into an economical factor and a social factor, and in case of the former, the children of low classes have been prevented from accessing to PC from the first, and the children of middle or upper classes have been limited to use PC telecommunication owing to the heavy maintenance cost. In addition, in case of the latter, they have been suffering pressure to use PC in accordance with informationalized society and control not to use PC by their parents for fear that PC may prevent their children from passing exams or studying, which is occurring in all kinds of sections such as school, family, and society owing to school life and studying. With this conception in mind, the children who don`t have PCs have suffered serious divested feelings and stresses compared with the children who have PCs, and the children who have PCs but can`t use PC telecommunication have showed a critical view and envied the children who use PC telecommunication. Also some children who use PC telecommunication have expressed their concrete dissatisfactions about PC telecommunication services and some have taken a positive viewpoint about informationalization. Thus firstly impartial information environment must be presented to various classes of children according to this unequally informative environmental structure for children, secondly a new educational paradigm, educational informationalization, must be received and realized, and finally the cognition of children`s rights to access to informationalization is required.
국내 소재 글로벌 제약사의 연구개발 규모 및 현황 : 2016~2020년 5년 간 설문조사
오인선(In-Sun Oh),조혜원(Hye Won Cho),이현주(Hyun Joo Lee),송혜원(Hye Won Song),한나래(Na Rae Han),김초롱(Cho Rong Kim),임혜인(Hye In Lim),신주영(Ju-Young Shin) 대한약학회 2021 약학회지 Vol.65 No.6
While the importance of the global pharmaceutical industry is growing owing to continued new drug developments and R&D investments, the scale of global pharmaceutical companies in Korea remains unclear. We therefore investigated the R&D status of global pharmaceutical companies in Korea through an annual survey from 2016 to 2020. We assessed five factors annually and their trend over the 5-year period: costs, personnel, number of clinical trials, number of clinical trial subjects, and others. We then examined the correlation among factors and further compared the trend between each factor and the gross domestic product (GDP). Of 35 companies that responded, 25 responded for five consecutive years and showed a steady increase in the cost, personnel, and the number of clinical trials. While costs and personnel increased more than the GDP over the 5-year period, the number of clinical trials remained similar; number of clinical trial subjects highly fluctuated year-by-year. Moreover, a high correlation was found for cost and personnel (r>0.8852), and cost and the number of clinical trials (r>0.8452). In conclusion, costs, personnel, and the number of clinical trials of global pharmaceutical companies in Korea steadily increased from 2016 to 2020 and thus, have continuously contributed to the domestic economy.
한국인의 일반 · 전문의약품-한약제제 병용 처방 실태분석 및 잠재적 상호작용 고찰
박상준(Sang-Jun Park),오인선(In-Sun Oh),박민정(Minjung Park),장보형(Bo-Hyoung Jang),신주영(Ju-Young Shin) 대한약학회 2022 약학회지 Vol.66 No.2
Herbal medicines have gained a reputation for being efficacious and safe over hundreds of years. Nowadays, people are easily exposed to drugs and herbal medications concurrently. Therefore, it is essential for regulatory authorities and physicians to closely monitor potential herb-drug interactions. The aim of this study was to determine (1) the prevalence of the concurrent use of drugs and herbal medications, (2) demographic and clinical characteristics of concurrent users, (3) risk factors associated with concurrent use, (4) prescription patterns, and (5) potential herb-drug interactions by using a nationwide insurance claims database. We included patients with herbal medicine records in 2010- 2015 from the National Health Insurance Service-National Sample Cohort 2.0. The herbal medicine users were divided into two groups: concurrent users who were prescribed both herbal and drug medications simultaneously and non-concurrent users. The proportion of concurrent use increased steadily from 2.5% in 2010 to 5.2% in 2015, and the growth rate in the elderly population aged 60-79 years was the highest, from 0.7% in 2010 to 2.8% in 2015. Concurrent users in 2015 were prone to be female; old; and have chronic diseases including hypertension (adjusted odds ratio [aOR], 4.89; 95% CI, 4.54-5.27), hyperlipidemia (aOR, 2.01; 1.89-2.14), and diabetes (aOR, 1.81; 1.67-1.98). The most common concurrently used combinations were Gunghatang-aspirin, Ojeoksan-aspirin, and Ojeoksan-atorvastatin. In this study, we investigated the herb-drug combinations that are used concurrently and related characteristics and elucidated the factors related to the concurrent use and the most common concurrently used herb-drug combinations.
건강보험청구자료를 이용한 HER2 양성 전이성 유방암 환자의 조기 사망에 따른 간접적 질병 부담 분석
고화연(Hwa Yeon Ko),최아형(Ahhyung Choi),홍빈(Bin Hong),배지환(Ji-Hwan Bae),오인선(In-Sun Oh),박선경(Sun-Kyeong Park),박연희(Yeon Hee Park),신주영(Ju-Young Shin) 대한약학회 2023 약학회지 Vol.67 No.3
The premature deaths caused by human epidermal growth factor receptor-2 protein (HER2) positive metastatic breast cancer (MBC) among working age groups result in significant socioeconomic losses. This study aims to quantify the socioeconomic burden of disease in female patients and provide evidence that can inform healthcare policy decisions. We identified deaths from HER2-positive MBC over the period from 2007 to 2021, using nationwide claims data of South Korea. Then, we estimated years of potential life lost (YPLL), years of potential productivity lost (YPPLL), and cost of productivity loss (CPL) to quantify socioeconomic burden of the disease. During the period from 2011 to 2020, a total of 3,576 patients died from HER2-positive MBC. The total YPLL over the period of 10 years from 2011 to 2020 was 128,605 years, corresponding to an average of approximately 36.0 years per deceased patient. The total YPPLL during the same period was 55,608 years, corresponding to an average of approximately 15.6 years per deceased patient. Additionally, total CPL of approximately 310 million won per deceased patient was incurred. All three disease burden indicators were highest among the age group of 40 to 54 years, which are individuals in their most productive time of life.
이명숙,오인선 한국가족복지학회 1997 한국가족복지학 Vol.2 No.2
This study is a review on the empirical reseach proving. that violent media provocates behavioral changes in terms of mind and action. Based upon data-gathering methodology, experiment, quasi-experiment, and correlational studies are divided and summarized. The conclusion from the review of experimental studies is that viewing of violent media enhances the viewer's violent motivation. Even though violent scenes result in severe cruel crimes in actual settings. The review of quasi-experimental studies is that viewing the violent scene itself does not affect youths'aggression, but it has aggressive youths become more aggressive. In contrast, the review of correlational studies is summarized that viewing of violent scenes and commiting of violent actions are in bi-directional causal relationship. The bi-directional causal relationship means that viewing of violent scenes cause aggressive behaviors, on the one hand and aggressive youths relative to non-aggersive youths have a tendency to prefer violent scenes, on the other hand. In conclusion, regardless of research methodology it is supported that viewing of violent has a tendency to increase youth's aggressive behavior. At least, no study supports the cathasis effect of violent scenes.