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소아에서 발생한 쯔쯔가무시 열에서 Azithromycin 치료 완치 4례
김은정,이창우,오연균,윤향석,김종덕,Kim, Eun Jung,Lee, Chang Yoo,Oh, Yeon Gyun,Yun, Hyang Suk,Kim, Jong Duck 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.2
저자들은 발열, 피부발진, 물린 부위의 가피(eschar) 등을 주소로 내원하여, 혈청학적으로도 쯔쯔가무시 열로 확진된 소아에서 5일 동안의 azithromycin 투약으로 특별한 합병증 없이 완치된 4례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Tsutsugamushi fever is a serious febrile disease outwardly similar to malaria and various arboviral infections. The endemic area is Asia-Pacific. This disease are generally associated with disturbed habitats favoring large populations of vector larval trombiculid mites. Therapy with tetracycline, chloramphenicol or ciprofloxacin is currently recommanded. Unfortunately these drugs is suboptimal for children and pregnant women. Recently, azithromycin has been proven to be effective in therapy of scrub typhus. There is no evidence that azithromycin causes adverse reaction to developing fetus or children. We report four cases of tsutsugamushi fever in children successfully treated with azithromycin. This is the first report describing clinical application of azithromycin to tsutsugamushi fever in Korean children.
속립성 폐침윤을 보인 갑상선 유두암 (Thyroid Papillary Carcinoma) 1례
최은정 ( Choe Eun Jeong ),김종률 ( Kim Jong Lyul ),이창우 ( Lee Chang U ),최두영 ( Choe Du Yeong ),오연균 ( O Yeon Gyun ),김종덕 ( Kim Jong Deog ),이광만 ( Lee Gwang Man ),박승택 ( Park Seung Taeg ),윤향석 ( Yun Hyang Seog ) 대한소아알레르기호흡기학회 2003 소아알레르기 및 호흡기학회지 Vol.13 No.4
Papillary carcinoma of the thyroid is the most common thyroid cancer in children. It usually occurs in the teenage female and presents as a mass within the thyroid itself. In the great majority of cases the only presenting sign is a neck mass. In a high p
김용권,최대호,황대성,오광수,오연균,윤향석,김종덕 圓光大學校 醫科學硏究所 1990 圓光醫科學 Vol.6 No.1-2
Tsutsugamushi disease is an acute febrile disease which is characterized by fever, lymphadenopathy, headache, rashes and eschar. The age incidence of reported cases is older than 20 years old. The prominent physical finding of diagnostic clues is eschar. We reviewed 7 cases of tsutsugamushi disease in childhood who were admitted to Wonkwang university hospital from October to November 1990. The clinical data were summarized as follows ; 1) Age distribution was between 2 year-old 14 year-old. The sex of all cases was male. 2) Geographically, 6 cases are in rural habitation. 3) The chief complaints were fever and chill (100%), and the commonest sign was rash (100%). 4) The antibody titers to all 3 prototype were 1 : 64 in 4 cases, 1 : 128 in 2 cases, and Gilliam type was 1 : 64 only in 1 case. 5) Laboratory findings showed leukocytosis in 1 case (14%), elevated aspartate aminotransferase (AST) in 5 cases (70%), elevated alanine aminotransferase (ALT) in 3 cases (43%). Urinalysis showed normal findings. The Chest X-ray revealed increased interstitial marking in 2 cases (28%). 6) All cases were treated with doxycyclin and mean defervescent period was 1.3 days.