GC/MS에 의한 담석과 담즙내의 Cholesterol, Bile Acids 및 Sterols의 동시 Profiling

양윤정,이선화,김현주,정봉철,Yang, Yoon Jung,Lee, Seon Hwa,Kim, Hyun Joo,Chung, Bong Chul 대한화학회 1998 대한화학회지 Vol.42 No.3

담즙산 분비 저하 및 콜레스테롤의 과도한 분비는 담석 형성의 주된 원인으로 담즙내의 담즙산과 콜레스테롤 및 그 전구 물질인 스테롤의 상대적인 농도는 담즙 성분의 이상을 알아보기 위한 중요한 지표로 알려져 있다. 이에 본 연구에서는 염기를 이용한 가수 분해와 pH 14와 1에서 두 번의 액체-액체 추출을 거친 후, $MSTFA/NH_4I$ 혼합액으로 유도체화 시키는 전처리 방법과 GC/MS를 이용한 새로운 분석 방법을 설정, 담즙산과 스테롤 그리고 콜레스테롤의 동시 분석을 시도하였다. 그 결고 회수율은 73.56-96.95% 이었고 within-a-day 및 day-to-day 분석의 RSD 값은 각각 1.72-13.79%, 0.68-14.10% 이었으며, 이 방법을 간내 담석증 환자에 적용하여 담즙과 담석내에 존재하는 7종의 스테롤과 5종의 담즙산, 그리고 콜레스테롤의 농도 및 그들간의 상대적인 농도 분포를 측정한 결과 담즙고 담석에서 현저히 다른 차이를 보였다. Cholesterol supersaturation in bile, which causes gallstone formation, is the result of low bile acid secretion or high cholesterol secretion. The quantitative analysis of cholesterol, bile acids and sterols which are precursors of cholesterol have been used to examine the changes in bile component. We described a simple, sensitive and reproducible method for simultaneous determination of cholesterol, five bile acids and seven sterols in human bile juices and gallstones by capillary column gas chromatography-mass spectrometry (GC/MS). Clinical samples were hydrolyzed by alcoholic KOH, extracted twice (pH 14 and 1) and derivatized to trimethylsilyl (TMS) ether with $MSTFA/NH_4I$ (N-methyl-N-trimethylsilyltrifluoroacetamide/ammonium iodide) mixture in order to be detected on the GC/MS. The good quality control data were obtained through within-a-day and day-to-day test (RSD values were 1.72-13.79, 0.68-14.10, respectively) and the recovery range of them was 73.56-96. 95 Using this method, biliary and gallstone compositions in the patients with intrahepatic stones were analyzed. The amounts and its relative distribution of cholesterol, bile acids and sterols showed different pattern in bile juices and gallstones.

The Entrapment of Vitamin E Acetate in Porous Spheres

양윤정,배봉진,이규식,전인구,Yang, Yoon-Jeong,Bae, Bong-Jin,Lee, Kyu-Sik,Chun, In-Koo 한국약제학회 1991 Journal of Pharmaceutical Investigation Vol.21 No.1

Porous spheres composed of natural waxes and inorganic materials containing vitamin E acetate as a drug were prepared by impregnation method. Furthermore, the amount of vitamin E acetate entrapped in the spheres and the release rate of vitamin E acetate from the spheres were studied. The impregnation of vitamin E acetate was carried out by dipping the spheres in vitamin E acetate solutions. Entrapment mechanism of vitamin E acetate could be expressed in terms of Langmuir's adsorption isotherm. The amount of vitamin E acetate entrapped in porous spheres was influenced by the structure and concentration of the polymer used in vitamin E acetate solutions, and the concentration of vitamin E acetate. Release characteristics of vitamin E acetate from the spheres were investigated by withdrawing samples periodically and analyzing them by spectrophotomer.

<조선왕조실록> 홍수 기록의 시.공간적 특성과 대응 양상 분석 : 홍수 리질리언스 사료로서의 가능성 탐색

양윤정(Yunjung, Yang),김지영(Jiyoung, Kim) 한국문화역사지리학회 2021 문화 역사 지리 Vol.33 No.4

오늘날 대형 태풍, 홍수, 신종 감염병 등과 다양한 재난 위협에 직면하여 사회 전반의 리질리언스를 확보하는 일이 시급하다. 이를 위해 동시대의 정형화된 재난데이터뿐만 아니라 해당 지역의 과거 재난기록에 대한 통시적인 고찰이 필요하다. 본 연구는 조선왕조실록 홍수 기록의 시·공간적 특성과 대응 양상을 분석하고, 오늘날 홍수 리질리언스를 높일 수 있는 자료로서의 가치를 탐색하였다. 먼저, 조선왕조실록홍수 기록을 조사하여, 기본 정보(실록명, 권차, 원문, 번역문), 시간정보(음력, 양력), 공간정보, 홍수피해유형, 구제 및 방재대책, 인문·사회요소 등을 포괄하는 데이터베이스를 구축하였다. 이를 바탕으로 조선왕조실록 홍수 기록의 데이터베이스를 분석하여 시·공간 패턴을 분석하였다. 마지막으로 조선시대 홍수 관리와 피해 구제에 대한 지식을 발굴하였다. 이번 연구는 조선왕조실록에 기록된 비정형 재난 기록들을 체계적으로 분석하고 홍수 리질리언스 증진을 위한 기반으로서의 가능성을 확인하였다는 점에서 의미가 있다. 향후 홍수 기록의 시·공간적 분포, 홍수방어 대책 등을 국토지리정보시스템 등 다양한 자료와 연계하는 연구를 심도 있게 진행한다면 홍수 리질리언스를 확보하는데 크게 기여할 수 있을 것이다. Building resilience against disasters, such as typhoons and floods, is being urgently requested. An emerging field of research to accomplish this is the integration of current disaster data with historical data. This study aimed to analyze floods’ temporal and spatial characteristics and response patterns in the “Veritable Records of the Joseon Dynasty (VRJD)” and explore where and how flood resilience could be optimized today. This study first investigated the flood records in the VRJD, and then established a comprehensive database including basic information, temporal data, damage types, and disaster relief measures. Based on this, the database of flood records in VRID was analyzed to examine the temporal and spatial patterns. Finally, the authors investigated the measures for flood management and disaster relief during the Joseon Dynasty. In-depth scrutiny linking the outcome of this study with various data, such as the Geographic Information System, would significantly contribute to secure flood resilience.

버넷의 「소공녀」와 「비밀의 정원」 에 재현된 모성

양윤정(Yunjeong Yang) 한국영미문학교육학회 2018 영미문학교육 Vol.22 No.2

This study intends to research Frances Hodgson Burnett’s changing idea of the role of motherhood in A Little Princess (1905) and The Secret Garden (1911). These popular novels contain a progressive view of women, especially motherhood. Sara’s mothering role in A Little Princess begins with taking care of her father and herself and extends to motherless students at the Minchin Boarding School and a hungry and poor child, Ann, on the street. In The Secret Garden, readers are invited to compare the roles of three mothers, Mrs. Lennox, Mrs. Craven and Mrs. Sowerby in light of ‘an angel in the house,’ the ideal woman in the Victorian Era. The role of motherhood extends to Dicon and Mary, Mr. Craven and even Mother Nature. In these novels, Burnett expands motherhood into society without limitation in the family. Also, she proves that motherhood is a great value and role that people of all ages and sexes should consider important and take part in. Burnett challenges patriarchal norms by promoting motherhood in the Victorian era, when women’s motherhood was undervalued.

SF와 미래사회 가르치기:

양윤정(Yunjeong Yang) 한국영미문학교육학회 2017 영미문학교육 Vol.21 No.2

This essay intends to research and teach the dystopian world of Stephen Spielberg’s A.I.Artificial Intelligence (2001, hereafter A.I.) and Brian Aldiss’s Science Fiction, Super-Toys Last All Summer Long and Other Stories of Future Time (1969) on which A.I. is based. A.I. is based on the screen script of a ‘Pinocchio’s picaresque robot version’ by Ian Watson, a British science-fiction author, which was based on Super-Toys Last All Summer Long, Carlo Collodi’s Adventures of Pinocchio (1883), and Hans Moravec’s Mind Children: The Future of Robot and Human (1988). A.I. includes Spielberg’s happy ending and family ideology. However, Kubrick’s influence is evident everywhere in the film: the family is the greatest horror when humans show their selfishness to non-humans. Gigolo Joe, an android robot, walks in his stride, who is more elegant and amoral than humans. In the Flesh Fair, robots are cruelly destroyed by humans. David in the amphibicopter has reached a deadlock with the statue of Blue Fairy. Above all, in the last scene of post-human beings, the revolved robots consider the ruins of humanity to be bleak. In this respect, the film A.I. represents a dystopian world based on Aldiss and Kubrick’s insight that Android goes beyond human beings in Spielberg’s family oriented film.

다양한 지면에서 주행 시 농업부산물 수집기 체결장치의 안전성 평가

양윤정 ( Yun-jeong Yang ),김정훈 ( Jeong-hun Kim ),장문경 ( Moon-kyeong Jang ),남주석 ( Ju-seok Nam ) 한국농업기계학회 2023 한국농업기계학회 학술발표논문집 Vol.28 No.1

본 연구에서는 기 설계된 농업부산물 수집기가 다양한 토양조건에서 주행 및 작업을 수행할 때 취약부인 체결장치에 발생하는 응력을 계측하고 정적 안전계수 및 피로수명을 도출하여 안전성을 평가하였다. 구조해석 시뮬레이션을 통하여 농업부산물 수집기의 체결장치에서 최대응력이 발생하는 지점을 확인하고 스트레인게이지를 활용한 응력 계측시스템을 구성하였다. 응력 계측을 위한 시험조건으로는 작업조건 3수준(수집작업 수행, 적재부 최고점 상승 상태에서의 주행, 적재부 최저점 하강 상태에서의 주행), 토양조건 4수준(비포장 평지, 포장 평지, 포장 경사지, 농지)으로 분류하였다. 각 조건에서 계측된 응력을 기반으로 정적 안전계수 및 피로수명을 도출하였다. 피로수명의 경우 상용 소프트 웨어인 nCode(nCode, HBM Prenscia, USA)를 사용하여 도출하였다. 시험 결과, 작업조건별 최대응력 및 평균응력의 크기는 수집작업 수행, 적재부 최고점 상승, 적재부 최저점 하강 순으로 나타났으며, 토양조건별로는 농지, 비포장도로, 포장 경사도로, 포장도로 순으로 나타났다. 정적 안전계수 도출 결과, 모든 작업조건에서 1.0 이상으로 도출되어 농업부산물 수집기는 정하중에 대해 안전한 것으로 판단된다. 또한, 국내 과수농가의 연간 평균 전정 작업시간 38.5 시간을 고려하였을 때 체결장치의 피로수명은 수집작업 수행 시에는 621 - 50,181년, 적재부 최고점 상승 상태 주행 시에는 1,060 - 302,337년, 적재부 최저점 하강 상태 주행 시에는 2,285 - 511,168년으로 나타났다. 국내 농업기계의 평균 내구 연수가 9년인 것을 고려하면 농업부산물 수집기 체결장치는 요구되는 수명기간 동안 안전하게 기능할 것으로 판단된다.

팀 버튼의 '이상한 나라의 앨리스'를 활용한 각색수업

양윤정(Yunjeong Yang) 한국영미문학교육학회 2015 영미문학교육 Vol.19 No.3

This paper explores the narrative structure and its representation in the film, Alice in Wonderland (2010) by Tim Burton and uses the same to adaptation in a literature class. Although Burton’s Alice in Wonderland is adapted from Lewis Carroll’s Alice in Wonderland (1865) and Through the Looking-Glass (1871), its narrative structure and artistic qualities differ from the original works. The film progresses quickly with confrontations between good and evil based on the structure of the hero’s journey. The narrative structure is Vogler’s principle of contemporary storytelling, derived from Joseph Campbell’s mystic studies. Button’s storytelling in the film, including organization of the film, the portrayal of the protagonist of Alice, the representation of Carroll’s satire reveals artistic values that are different from the Alice books. In an age of when literary works are used in various film contexts, Disney, one of the successful film companies in Hollywood, albeit sometimes controversial, is noteworthy. Disney’s story conferences produce the successful narrative structure of the hero’s journey and their artistry directors represent narratives in films in their own ways. In this context, the research on Burton’s Alice in Wonderland shows Disney’s popular and successful way of adapting literary works, their narratives and representations.

티치아노의 〈나에게 손대지 말라〉 연구

양윤정(Yang YoonJung) 서양미술사학회 2010 서양미술사학회논문집 Vol.33 No.-

Titian’s Noli me tangere, which is currently possessed by the National Gallery in London, is presenting the dramatic scene in the Gospel of John. Compared with previous or contemporary paintings in Rome and Florence with same theme, it is very unique in terms of iconography and composition. Since the middle ages, ‘Noli me Tangere’ had been treated as a major theme of Christ’s resurrection. Mostly, resurrected Christ wearing toga or shroud (sometimes carrying a hoe in his hand) rebuffed Mary Magdalene who was about to approach to Jesus Christ with full of joy. However, the way Titian painted this subject was far from the traditional iconography and composition. Christ with nudity takes a dramatic gesture toward Mary Magdalene, gazing directly and tenderly into her eyes. Titian’s Noli me Tangere reflects the religious and cultural circumstances of Venice. Titian executed this painting to represent venetians who endeavor to overcome all difficulties of Venice with sincere piety. In order to fully understand the theme and iconography of this painting, it is indispensable that we consider the context of complex situations of Venice in early sixteenth century. The League of Cambrai, including Roman Papal State, France, Milan, Spain, Holy Roman Empire, delivered a containing attack against Venice to obstruct venetian expansion. As a result, most of terraferma in Venice such as Padua, Brecia and Bergamo were lost. Furthermore, conflagration in Rialto, famine and black plague made the city even worse. In 1509, Roman Pope, Jullius II, finally excommunicated Venice from the Catholic Church. Isolated venetians were engrossed in their own religious activities like grand processions or liturgy dramas. Originally, liturgy drama was designed to make the new baptized or illiterate Christians understand the biblical contents better and easier. In liturgy drama, Christ was given a new character as not an austere teacher but a tender adviser or guider. In Titian’s painting, Christ is representing this new character of Christ. Titian took one more step forward to further, presented Christ with nudity. Body of Christ(Corpus Christ) had been core in incarnation theology, reminding Christ’s sacrifice and Eucharist. Especially, Christ as young nude male had been shown of humanity of Holy Son. In the period of Cambrai League, strong doubts were expressed in Venice and venetians tried to purge themselves from sinful lives by following incarnation theology. Incarnation theology, also, influenced in venetian renaissance paintings that describe the moment of Christ’s resurrection, such as Giovanni Bellini and Jacopo Tintoretto. Titian’s Noli me Tangere functioned as a visual representation of the Catholic dogma and Christ’s new character in liturgy drama. The innovative iconography and its composition perfectly fit into these contexts. In sum, iconography and composition of Noli me Tangere are results of re-construct to fit into the religious and cultural context in early sixteenth century Venice.

20세기초 지형도로 본 제주

양윤정(Yang, Yun-jung),박선영(Park, Seon-young) 한국고지도연구학회 2020 한국고지도연구 Vol.12 No.2

본 논문은 20세기에 제작된 제주도 지형도 현황을 파악하고, 이 가운데 20세 초 한국 근대지형도에 반영된 지리정보를 통해 제주도의 자연환경은 물론 이 시기 변화한 경관을 연구하는데 목적으로 하였다. 이를 위하여 19세기 말에서 20세기 초에 제작된 1:50,000 제주 근대 지형도를 분석 대상으로 하여 1910년대 11장, 1950년대 8장, 1970년대 6장에 대하여 각 시기별로 제작된 지형도의 특징을 살펴보았다. 그리고 《大東輿地圖》와 『民籍統計表』, 『新舊對照朝鮮全道府郡面里洞名稱一覽』, 『地方行政一覽表』를 통해 지명을 비교하고 당시 행정구역을 복원하였다. 이를 토대로 20세기 초에 제작된 근대지형도를 활용하여 이 시기 제주도의 행정구역, 지명, 하천의 지리정보를 파악하고, 역사지리환경을 확인하였다. 따라서 본 연구는 한국근대지형도에 표기된 지명과 지리정보를 활용하여 20세기 초 제주의 모습을 확인할 수 있었다는데 의의가 있다. The purpose of this paper is to investigate the current status of the modern maps of Jeju Island which had been produced in the early 20th century and to scrutinize the natural environment and landscape change of Jeju island in this period through geographic information reflected in modern topographic maps of Korea. To this end, the authors investigated the characteristics of the 1:50,000 topographic maps of Jeju Island that had been produced from the late 19th century untill the early 20th century on the basis of the analysis of 25 topographic maps; 11 produced in the 1910s, 8 in the 1950s, and 6 in the 1970s. In addition, geographical names was compared and information on administrative districts at that time was restored through the investigation of 《大東輿地圖(Daedongyeo-jido)》와 『民籍統計表(Minjeok-tonggyepyo)』, 『新舊對照朝鮮全道府郡面里洞名稱一覽(Shingudaejo-joseon-jeondobugunmyeonridong-myengchingillam)』, 『地方行政一覽表(Jibanghaengjeong-illampyo)』. Integrating this restored information with the modern topographic map produced in the early 20th century, the authors identified the geographical information of administrative districts, geographical names, and rivers of Jeju Island during this period and confirmed the historical geographic environment at that time. Therefore, this study is meaningful in that the appearance of Jeju Island in the early 20th century was restored by using place names and geographic information reflected on the modern topographic maps of Korea.

홀란드의 영화 <비밀의 정원>: 모성적 공간에서 치유되는 주인공들

양윤정 ( Yun Jeong Yang ) 건국대학교 동화와번역연구소 2011 동화와 번역 Vol.22 No.-

아그네츠카 홀란드(Agnieszka Holland)의 영화 <비밀의 정원>(The Secret Garden 1993)은 프란시스 호지슨 버넷(Frances Hodgson Burnett)의 원작소설 『비밀의 정원』(The Secret Garden 1911)을 바탕으로 제작되었다. 홀란드의 영화 비밀의 정원 은 작품성있는 ``가족영화``로서 비디오로 팔렸으며 상업적으로 성공했다. 이영화는 원작소설『비밀의 정원』의 주제인 모성적 공간인 정원에서 아이들이 치유되는 이야기이다. 그렇다면 이러한 텍스트가 영화감독을 매료한 것은 무엇이고 그렇지 않은 것은 무엇인가? 하나의 매체가 다른 것으로 각색될 때, 특히 장편의 복잡한 소설이 시간제약과 시각적인 강조점을 가지는 영화로 만들어질 때 다른 점이존재하는 것은 피할 수 없다. 특히 영화 진행에 필요한 정보를 주기 위한 도입부분에서 플롯을 파괴하여 재배열하면서 그 특성이 많이 달라진다. 비밀의 정원 은원작소설의 플롯을 그대로 가지고 있지만 두 매체간에 서로 다른 요소들이 존재하는데, 본 연구는 텍스트와 영화를 함께 살펴보면서 이러한 다른 점들 가운데, 영화의 도입부분, 메리와 콜린에 대한 묘사, 어머니의 부재, 정원과 정원의 마법, 치유, 그리고 결말부분의 메리의 비중에 대하여 탐색한다. Agnieszka Holland`s film, The Secret Garden(1993) is based on Frances Hodgson Burnett`s children`s novel, The Secret Garden(1911). Holland`s film, The Secret Garden is a family film which is sold as a video and highly acclaimed for both its cinematic quality and its popularity. This film has a theme of main characters cured in the garden, the maternal space. If so, what is it the text attracts or does not attract the director? Of course there are differences when a work in one medium is translated into another, especially when a lengthy and complex novel is made into film with its time limitation and emphasis on the visual. They need to collapse and rearrange plot elements, particularly at the beginning, to give necessary information and get on with the story which could make the differences between the two media a lot. Holland`s The Secret Garden has a plot of the orignal text but there exist different elements between two media. These major different elements are explored in this study: the opening scenes, the description of Mary and Colin, absence of mother, garden and its magic and the cure and the importance of mary in the conclusion.