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김유찬,김홍식,박향준,신용우,윤형근,정성훈 ( You Chan Kim,Hong Sik Kim,Hyang Joon Park,Yong Woo Cinn,Hyong Guen Yun,Sung Hoon Jung ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.5
Keloids are benign fibrcus growths which extend beyond the original wound and rarely regress. Available methods of treatment include surgical excision, radiotherapy, intralesional steroid injection, cryotherapy, systemie. chemotherapy, zinc tape strapping, pressure, silicon gel and combined therapy. Postoperative irradiation is a useful and effective method of eradication or prevent.ion of keloid. We describe two cases of the prevention of keloids associated with post,operative irradiation. (Korean J Dermatol 1997;35(5): 1009-1012)
김홍식,김유찬,박향준,신용우 ( Hong Sik Kim,Yoo Chan Kim,Hyang Joon Park,Yong Woo Cinn ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.6
Sarcoidosis is a multisystemie disease of unknown cause eharacterized by the formation of noncaseating granulomas that n,ay involve any organ, but the most common sites are the lungs, lyrnph nodes, skin, and eyes. We report a case of sarc( idosis which may be caused by a foreign body reaction. A 49-year-old women was presented with violet colored, scaly papules on t.he back and subcutaneous nodules on the left index finger, which had been present for 6 months. A biopsy of a nodule on the left index finger reveal .d noncaseating epithelioid cell granuloma throughout the dermis with foreign body in the center of the granuloma. Under the polarized light microscopy, tiny particles of foreign material were more obvious. We think that foreign material may actually serve as a nidus for granuloma format.ion in sarcoidosis. (Korean J Dermatol 1997;35(6): 1254-1257)
Ribavirin ( Virazole ) 의 대상포진에 대한 치험
김광중,신용우,이유신,김원석,성경재,김홍석 대한피부과학회 1980 大韓皮膚科學會誌 Vol.18 No.6
Ribavirin(l-β-D-ribofuranosyl-l, 2, 4-triazole-3-carboximide, Virazole^R) is a. synthetic nucleoside derivative with reported broad spectrum activity in vitro and in vivo against a wide variety of DNA and RNA viruses. This drug works by selective inhibition of viral protein in the early stage of viral replication, but does not influence on host cell protein. The present study was undertaken to evaluate the therapeutic effect of Ribavirin in patients with herpes zoster. A total of 15 patients entered this study at the Department of Dermatology, Seoul National University Hospital during 5 months' period, from May, 1980 to September, 1980, Ribavirin(10mg/kg/d) was given to 10 patients. After initiation of therapy, we observed duration of pain and vesicles and onset of crust formation in each patient clinically. The results observed in the 15 patients were as follows. 1. The average duration of pain was 6. 0 days in Ribavirin group and 8. 6 days i@n. control group (p$lt;0. 05). 2. Postherpetic neuralgia was not @found in any patients treated with Ribavirin. 3. The average duzation of all vesicles and onset of crust formation were 7. 0 days and 3. 8 days in Ribavirin group and 7. 2 days and 4. 2 days in control group respectively. 4. No side effects were observed during the course of Ribavirin treatment.