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신동민,정우진,안희배,Dong Min Shin,M,D,Woo Jin Jeung,M,D,Hee Bae Ahn,M,D 대한안과학회 2008 대한안과학회지 Vol.49 No.1
`Purpose: To evaluate the effect of unilateral blepharoptosis repair on contralateral eyelid position. Methods: The medical records of 39 patients who had undergone unilateral blepharoptosis repair were reviewed for preoperative and postoperative margin reflex distance (MRD). Results: Of the 39 patients, 28 (71.8%) had congenital ptosis and 11 (28.2%) revealed acquired ptosis. Twenty-two (56.4%) patients were male and 17 (43.6%) were female. Ages ranged from 3 to 55 years (mean 15.3±20.1 years). After unilateral blepharoptosis repair, the postoperative mean (±SD) change in MRD of nonoperated eye was -0.3±0.7 mm at week one, -0.3±0.6 mm at three months, and -0.2±0.7 mm at six months. Conclusions: After unilateral blepharoptosis repair, 35.9% of patients had a decrease in contralateral eyelid height at postoperative 3 months and amount of decrease was 0.2±0.7 mm.`
생체 내에서 배양한 각막윤부 상피세포 이식술의 장기 경과 관찰 결과
천현철,신동민,이동준,박우찬,Hyun Chul Cheon,M,D,Dong Min Shin,M,D,Dong Joon Lee,M,D,Woo Chan Park,M,D 대한안과학회 2008 대한안과학회지 Vol.49 No.3
`Purpose: To investigate the characteristics and the results of long-term follow-up of limbal epithelial cells cultivated in vivo on amniotic membranes (LIVAM) in corneal limbal deficiency. Methods: Twenty-two eyes of twenty-two patients diagnosed with corneal limbal deficiency underwent transplantation of in vivo cultivated corneal limbal epithelial cells on the amniotic membrane. Biopsy and immunohistochemical staining (AE5, MUC5AC) of the amniotic membrane cultivated for one week were performed to verify that the cultivated epithelial cells on the amniotic membrane were corneal epithelial cells. Impression cytology was performed to evaluate the characteristics of the transplanted corneal limbal epithelial cells at postoperative 1 week, 3 months, 6 months, and 1 year. Results: Successful epithelial growth was observed on the amniotic membrane at one week. The epithelial cells were confirmed to be corneal epithelial cells by immunohistochemical staining. Transplanted in vivo cultivated corneal epithelial cells were confirmed to have corneal specificity by impression cytology and immunohistochemical staining at postoperative 1 week, 3 months, 6 months, and 1 year. Conclusions: In vivo cultured corneal epithelial cells showed morphological and immunohistochemical findings similar to those of normal corneal epithelial cells. Transplanted in vivo cultivated corneal epithelial cells were maintained and showed the characteristics of corneal epithelial cells. Transplantation of in vivo cultivated corneal limbal epithelial cells can be performed to reconstruct the corneal limbus in treating corneal limbal deficiency. `