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손효성,오창근,김문범,이재봉,장호선,권경술 대한피부과학회 2003 대한피부과학회지 Vol.41 No.6
Trichorhinophalangeal syndrome(TRPS) typeⅠis characterized by sparse and slow-growing hairs, pear-shaped nose, elongated philtrum, thin upper lip, and bone deformities, especially, cone-shaped epiphyses of the phalanges. The syndrome is inherited in an autosomal dominant manner. We report a case of TRPS typeⅠ with alopecia like male pattern baldness and Perthes-like changes on the right hip joint. (Korean J Dermatol 2003;41(6) : 801~804)
하지 정맥류 혈관벽의 구조 및 구성 성분 변화에 대한 전자현미경학적 연구
손효성 ( Hyo Sung Son ),오창근 ( Chang Keun Oh ),이재봉 ( Jae Bong Lee ),김문범 ( Moon Bum Kim ),장호선 ( Ho Sun Jang ),권경술 ( Kyung Sool Kwon ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.7
N/A Background : Over the years many possible explanations for the development of varicose vein have been suggested. The main possible mechanisms are a valvular failure theory and a weak wall theory. However, the definite cause of varicose has not been determined yet. Objective : The aims of this study are to observe the pathologic changes in the smooth muscle cells and extracellular matrix of the primary varicose vein. An understanding of the pathology may possibly help to understand the pathogenesis of varicose veins. Methods : A total of 20 vein specimens of primary varicose vein were collected from 13 patients who underwent ambulatory phlebectomy. Among them, 16 specimens were thick segments and 4 specimens were thin segments of varicose veins. Control samples were collected from two patients with no history and clinical evidence of varicose vein. Each specimen was examined with a JEM 1200EX-Ⅱ electron microscopy. Ultrastructural findings between thick and thin segments of varicose veins and normal veins were also compared semiquantitatively. Results : The smooth muscle cells of varicose veins were abnormal in shape and lost their fusiform appearance with many vacuoles. Increased extracellular matrix shows the increase of degenerated collagen fibers and decrease of elastic fibers. Thick segments showed increased collagen fiber. Conclusion : These ultrastructural changes may be not the primary cause of varicose veins but the secondary remodeling processes of vein walls by hemodynamic stress. (Korean J Dermatol 2003;41(7) : 899~907)
마인드맵을 활용한 회상치료가 여성 치매 의심 노인의 인지기능, 우울 지수 및 삶의 질에 미치는 영향
장우혁,손효성,서예지,윤수정,김현지 고령자・치매작업치료학회 2018 고령자.치매작업치료학회지 Vol.12 No.2
Objective : The purpose of this study was to investigate the effects of reminiscence therapy using mind map to improve cognitive function, depression index, quality of life for old woman with dementia. Method : The study were 14 patients who were diagnosed with a woman suspected of dementia. They were randomly assigned to Study group(N=7) and control group(N=7). All patients received only to Study groups. reminiscence therapy using mind map was composed to 10 sessions, 40 minutes per sessions, 2 times a week, for 5 weeks. For result analysis, descriptive statistic, Wilcoxon signed rank test, and Mann-Whitney U test were used. The evaluation tools were Mini-Mental State Examination Korean Version (MMSE-K), Korean Version of Beck Depression Inventory (K-BDI), Korean Version of the World Health Organization Quality of Life Scale Abbreviated Version (WHOQOL-BREF). Result : There was a significant difference in cognitive function, depression index, and quality of life in the within group after intervention, and there was a significant difference in cognitive function in the between group comparison. Conclusion : According to the results of study, an easing effect was confirmed regarding reminiscence therapy using mind map for an old woman with dementia. using reminiscence therapy using mind map when applied to the improvement of cognitive function, depression index, quality of life. 목적마인드맵을 활용한 회상치료가 여성 치매 의심 노인의 인지기능과 우울 지수 및 삶의 질에 미치는영향을 알아보고자 하였다. 연구방법본 연구는 무작위 대조군 전·후 실험설계를 사용하였다. 연구 대상자는 여성 치매 의심 노인으로실험군 7명, 대조군 7명으로 이루어져 있다. 모든 대상자는 중재 기간 동안 동일하게 20분간 그리기 활동에 참여하였고, 실험군은 추가로 마인드맵을 활용한 회상치료를 적용하였다. 마인드맵을 활용한 회상치료는 5주간, 주 2회, 1회당 40분씩 총 10회기로 구성하였다. 중재 효과를 검증하기 위해 사용된 평가도구로 인지기능은 간이 정신상태 검사-한국판(Mini-Mental State Examination Korean Version ; MMSE-K), 우울 지수는 벡 우울증 척도 한국판(Korean Version of Beck Depression Inventory ; K-BDI), 삶의 질은 한국판 세계보건기구 삶의 질 간편형 척도(Korean Version of the World Health Organization Quality of Life Scale Abbreviated Version ; WHOQOL-BREF)를 사용하였다. 결과 분석은 기술 통계와 맨-휘트니 검정(Mann-Whitney U test), 윌콕슨 부호 순위 검정(Wilcoxon signed rank test)을 시행하였다. 연구결과중재 후 집단 내에서 인지기능, 우울 지수, 삶의 질에 유의한 차이가 있었고, 집단 간 에서는 인지기능에 유의한 차이가 있었다. 결론마인드맵을 활용한 회상치료가 여성 치매 의심 노인의 인지기능과 우울 지수 및 삶의 질에 긍정적인 효과가 있음을 확인하였다.