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김문범 ( Moon Bum Kim ),김범준 ( Beom Joon Kim ),서영준 ( Young Joon Seo ),이양원 ( Yang Won Lee ),이애영 ( Ai Young Lee ),김규한 ( Kyu Han Kim ),김명남 ( Myeung Nam Kim ),김진우 ( Jin Woo Kim ),노영석 ( Young Suck Ro ),박영민 ( Y 대한피부과학회 2009 대한피부과학회지 Vol.47 No.5
Background: Interplay of numerous constitutional and precipitating factors are involved in the development of atopic dermatitis (AD). Most of these etiologic factors are not controllable, but barrier dysfunction can be managed. Correction of barrier abnormalities has been accepted as a first-line therapy with effective anti-inflammatory therapy. Objective: We wished to establish standardized skin care guidelines for Korean patients who suffer from atopic dermatitis. Methods: The skin care guidelines were proposed by the Korean Atopic Dermatitis Association (KADA), with a particular emphasis for barrier dysfunction in AD from a review of more than 100 published studies and related documents in the clinical literature by a task force team (TFT) of the KADA. The TFT also evaluated the reliability of the studies based on scientific evidence and the size of the study populations. The TFT disregarded controversial findings and summarized all of the collected studies. Results: Skin care guidelines were proposed by the KADA, particularly for barrier dysfunction in AD. A warm bath for approximately 20 minutes was recommended once daily. Soap can be used two or three times per week and aggressive skin scrubbing should be avoided. A topical moisturizer should be applied at least twice a day. Immediate application of emollient is required after bathing. The donning of clothing made of cotton is recommended. Nails should be cut short to reduce skin damage caused by a skin scratch. Conclusion: Application of moisturizer immediately after appropriate bathing may be the most important treatment for skin care. A topical steroid should be used whenever AD develops. Nail care and proper clothing are also be helpful for the prevention of dermatitis aggravation. Proper ways to bathe, use of moisturizer and topical steroids and nail care and appropriate clothing were considered. (Korean J Dermatol 2009;47(5):531~538)
다발성 피지낭종 54예의 임상 , 병리조직 및 면역조직화학적 연구
김문범(Moon Bum Kim),장호선(Ho Sun Jang),오창근(Chang Keun Oh),권경술(Kyung Sool Kwon) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.12
Background:Steatocystoma multiplex is a rare but well-known disorder characterized clinically by the formation of numerous cutaneous cysts and histopathologically by a undulated hyalinized cuticle and sebaceous glands within or close to the cyst walls. However the clinical and histological features can be variable and may mimic other other cystic tumors. Objective:The purpose of study was to characterize the clinical and histopathological features of steatocystoma multiplex and to assess the effectiveness of cytokeratin 10 and 17 stain in differentiating steatocystoma multiplex from epidermal cysts. Methods:A total of 54 cases of SM diagnosed at the Department of Dermatology, Pusan National University Hospital(PNUH) were reviewed clinically and histopathologically. To compare the staining pattern of Cytokeratin 10 and 17 between steatocystoma multiplex and epidermal cyst, we used monoclonal mouse anti-human cytokeratin 10 and cytokeratin 17. Results 1. Male to female ratio is 1.4:1, and family history is identified in only 4 cases. 2. The mean age at visit and at onset of the lesions are 32 years(range:16 - 58) and 25.8 years(range:13 - 58). 3. The major lesional sites at visit were the upper extremities(14 cases, 50%) and chest(13 cases, 46%), and those at onset were the upper extremities(7 cases, 25%) and axillae(6 cases, 22%). 4. Atypical histopathologic findings, such as round or oval cystic wall(25 cases, 46%), vellus hair in cystic wall(2 cases, 4%), foreign body granuloma reaction(1 case, 2%), or the cases not showing the diagnostic histopathologic findings(2 cases, 4%) are frequently noted. 5. Cytokeratin 10 and 17 immunohistochemical staining are helpful in discriminating steatocystoma multiplex from epidermal cyst. Conclusion:It is interesting that steatocystoma multiplex has more clinical and histopathological findings than the previous reports, and characteristic response to Cytokeratin 10 and 17.
Short Report / 다발성 에크린 한선낭종 2예
김문범(Moon Bum Kim),장호선(Ho Sun Jang),오창근(Chang Keun Oh),권경술(Kyung Sool Kwon) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.10
Eccrine hidrocystoma is a benign eccrine duct-derived cyst which may be solitary or multiple. We report two cases of multiple eccrine hidrocystoma, which have two points of sameness in middle aged women and worsening of the condition in summer and improvement in winter. Recently, the incidence of multiple eccrine hidrocystoma seems to be decreasing due to well-developed cooling devices in summer. In spite of its decreasing incidence, we think that it is still noteworthy to keep in mind the possibility of eccrine hidrocystoma when a patient presented with multiple facial papules in hot season. (Korean J Dermatol 2000;38(10):1388~1391)
김문범 ( Moon-bum Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
Education: 1986-1992 Pusan National University College of Medicine, Busan, Korea 1997-1998 Pusan National University College of Medicine, Busan, Korea 2003-2009 Pusan National University College of Medicine, Busan, Korea Training and Fellowship Appointments: 1997-2000 Dermatology Residency, Pusan National University Hostpital, Busan, Korea 2001-2002 Dermatology Fellow, Pusan National University Hospital, Busan, Korea Faculty Appointment: 2003-2005 Clinical Assistant professor, Pusan National University Hospital, Busan, Korea 2006-2007 Assistant Professor, Pusan National University College of Medicine, Busan, Korea 2008-2012 Associate Professor, Pusan National University College of Medicine, Busan, Korea 2013- Professor, Pusan National University College of Medicine, Busan, Korea Memberships: 1997-present Korean Dermatological Association 2006-present Korean Hair Research Society 2006-present Koean Society for Atopic Dermatitis 2006-present Society for Investigative Dermatology
김연아 ( Yeona Kim ),하대룡 ( Dae-lyong Ha ),손진화 ( Jin-hwa Son ),신기혁 ( Kihyuk Shin ),이정수 ( Jungsoo Lee ),김훈수 ( Hoon-soo Kim ),고현창 ( Hyun-chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon-bum Kim ) 대한피부과학회 2020 대한피부과학회지 Vol.58 No.9
A poroma is a benign adnexal neoplasm originating from the sweat gland duct. It usually presents clinically as a soft erythematous or flesh-colored papule, plaque, or nodule on the palms and soles. In most cases, poromas manifest as a solitary lesion, but rarely, multiple lesions have been reported and are defined as poromatosis. Although the pathogenesis is unclear, poromatosis is known to be associated with actinic damage, human papillomavirus infection, radiation therapy, or polychemotherapy. Herein, we describe a 53-year-old woman who had multiple erythematous papules on her feet for a year. She had a medical history of acute lymphoblastic leukemia and had undergone polychemotherapy with stem cell transplantation. To our knowledge, poromatosis related to chemotherapy is a rare entity, and our case could be attributed to the theory that using polychemotherapy can induce poromatosis. (Korean J Dermatol 2020;58(9):617∼619)
김연아 ( Yeona Kim ),하대룡 ( Dae-lyong Ha ),손진화 ( Jin-hwa Son ),신기혁 ( Kihyuk Shin ),이정수 ( Jungsoo Lee ),김훈수 ( Hoon-soo Kim ),고현창 ( Hyun-chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon-bum Kim ) 대한피부과학회 2020 대한피부과학회지 Vol.58 No.9
Background: Tumoral calcinosis is characterized by the deposition of calcific masses around major joints, and it often causes significant impairment of joint function. Dermatologists sometimes encounter patients with a subcutaneous hard mass around the joint. However, there are few studies about tumoral calcinosis in the dermatologic literature, especially in Korea. Objective: The aim of this study was to determine the clinical characteristics of tumoral calcinosis. Methods: We reviewed the clinical photographs, medical records, and biopsy specimens of 11 cases of tumoral calcinosis seen at our clinic in 10 years. Results: All 11 patients were female, and the mean age at onset was 58.5 years. The mean duration of the disease was 7.1 years. Most patients (9, 81.8%) presented with an asymptomatic subcutaneous hard mass around the iliac crest. None of the patients had a family history, or abnormal serum calcium, phosphorus, and parathyroid hormone levels. All patients underwent surgery for treatment. Conclusion: Tumoral calcinosis can occur sporadically without metabolic disease. Therefore, careful history taking and biochemical work-up involving the metabolism of calcium and phosphorus should be performed. If there is no peculiarityon examination, the lesion is cured by resection. Although the sample size of this study is small, it can be inferred that the characteristics of tumoral calcinosis in Korea can be described by its predominant sex preponderance and location, that is, the female sex and the iliac crest, respectively. (Korean J Dermatol 2020;58(9):596∼600)