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온도 감응성 MPEG-PCL 하이드로젤을 이용한 단백질의 서방화
서광수 ( Kwang Su Seo ),홍금덕 ( Keum Duck Hong ),현훈 ( Hoon Hyun ),김문석 ( Moon Suk Kim ),강길선 ( Gil Son Khang ),이해방 ( Hai Bang Lee ) 한국조직공학과 재생의학회 2005 조직공학과 재생의학 Vol.2 No.2
The temperature sensitive hydrogels were synthesized by the terminal alcohol of methoxy poly(ethyleneglycol) (MPEG) as an initiator via ring-opening of ε-caprolactone (ε-CL) in the presence of HCl·Et2O as a monomer activator. The gel-to-sol transitions of MPEG-PCL diblock copolymer solutions were also examined in deionized water according to polymer concentration. The MPEG-PCL block copolymers were dissolved in water at 80oC and stored at 4oC for 15 hours. The polymer solutions formed sol around at the room temperature. The formed sol became gel from 31oC to 53oC by increasing the temperature. To observe the release behavior of protein based on MPEG-PCL block copolymers, hydrogels loaded proteins such as albumin, insulin, and dextran were easily fabricated by mixing polymer solution and proteins. The release profile of proteins in MPEG-PCL hydrogels showed the sustained zero-order release without initial burst for 20 days. In conclusion, we confirmed that MPEG-PCL temperature sensitive hydrogels is useful as controlled protein carriers.
경상북도 봉화군 석포면 석개재 일대에 분포하는 전기 오르도비스기 두무골층에 대한 고생물학적 연구
서광수(Kwang-Soo Seo),이병수(Byung-Su Lee) 한국고생물학회 2010 고생물학회지 Vol.26 No.1
이 연구는 경상북도봉화군 석포면 석개재 지역에 분포하는 두무골층에서 산출된 코노돈트를 이용하여 이 층의 지질시대를 추정하는 데 있다. 이 층의 하부는 녹회색 셰일, 리본암 그리고 얇은 석회암이 협재된 실트암으로, 중부는 셰일이 협재된 청회색 석회암으로, 그리고 상부는 석회질 셰일과 석회암이 교호층으로 구성된다. 석회암표품은 32개를 채취하였으며, 이중20개의 표품에서 171개체의 코노돈트가 산출되었다. 코노돈트는 8속 12형태종과 6속 9복합요소 종으로 분류된다. 선별한 코노돈트는 Acodus deltatus, Cornuodus long-ibasis, Drepanodus arcuatus, Drepanoistodus basiovalis, Drepanoistodus inaequalis, Distacodus dumugo-lensis, Oistodus linguatus, Utahconus beimadaoensis, Oistodus muticorrugatus, Scanodus rectus, Scanodus furnishi, Scolopodus rex huolizhaiensis, Paltodus quinquecostatus, Scolopodus quadrangulatus, Paltodus detifer, Scolopodus flexilis, Teridontus nakamurai, Triangulodus dumugolensis, Variabiloconus bassleri, 그리고 Walliserodus ethingtoni이다. 두무골층은 생층서학적으로 2대로 나누어졌다. 즉, 하부와 중부은 미분류대로, 그리고 상부는 Triangulodus dumugolensis 帶를 설정하였다. Triangulodus dumugolensis 帶는 북유럽의 Prioniodus elegans 帶, 북미의 Oepikodus communis 帶, 북중국의 Scalpellodus tersus 帶에 각각 대비된다. 두무골층의 상부의 지질시대는전기 오르도비스기로유럽 지역의 중기 Arenig통에, 그리고북아메리카지역의 Canad조에 각각 대비된다. This study is to clarify the geologic age of the Dumugol Formation in the Seckgaejae area on the basis of the conodont fauna. The Dumugol formation is composed of greenish shale, ribbon rock and siltstone containing thin limestone in the lower part, of bluish limestone with minor interbeds of shale in the middle part, and of calcareous shale intercalated with limestone in the upper part. For conodont study, 32 limestone samples were collected from four measured sections, and 171 identifiable conodont specimens were obtained from 20 productive samples. Conodonts from the Dumugol Formation are classified into 9 multielement species referable to 6 genera, and 12 form species belonging to 8 genera. The representative specimens from the Dumugol Formation in this area are Acodus deltatus, Cornuodus longibasis, Drepanodus arcuatus, Drepanoistodus basiovalis, Drepanoistodus inaequalis, Distacodus dumugolensis, Oistodus linguatus, Utahconus beimadaoensis, Oistodus muticorrugatus, Scanodus rectus, Scanodus furnishi, Scolopodus rex huolizhaiensis, Paltodus quinquecostatus, Scolopodus quadrangulatus, Paltodus detifer, Scolopodusjlexilis, Teridontus nakamurai, Triangulodus dumugolensis, Variabiloconus bassleri, and Walliserodus ethingtoni. The Dumugol Formation is divided biostrati-graphically into two zones, viz, Unnamed Zone in tbe lower and middle part and Triangulodus dumugolensis Zone in the upper part. Triangulodus dumugolensis Zone ofthis study is correlated with those of the Scalpellodus tersus Zone of North China, Oepikodus communis Zone ofNortb America, Prioniodus elegans Zone of Baltic region. The geologic age of the upper part of the Dumugol Formation is the early Arenigian series in Europe and the Canadian stage in North America.
서광수 ( Kwang-su Seo ),황수진 ( Soo-jin Hwang ) 한국환경과학회 2018 한국환경과학회지 Vol.27 No.3
Observations were conducted in Uiseong Binggye-ri Ice Valley of Korea, where a low temperature talus is located. The talus temperature at Ice Hole near the lower end of the talus remained at 0°C until summer or autumn and averaged -0.3°C over 2 years. The talus temperature at Warm Hole was much higher than the external air temperature during autumn and winter. The outflow of warm air at Warm Hole begins in the late summer of fall. The direction of airflow through the talus surface was determined by the relationship between talus temperature and external air temperature. Annual variations in talus temperature and air exchange between the talus and the external environment can be divided into four periods. It was found that the airflow directions at Warm Hole and Ice Hole were not necessarily opposites. The outflows from the talus at Ice Hole and Warm Hole can occur simultaneously.
니켈나노파우더 함침기법을 이용한 탄소복합소재의 전자파차폐 효과에 관한 연구
서광수(Kwang-Su Seo),곽이구(Lee-Ku Kwac) 한국기계가공학회 2020 한국기계가공학회지 Vol.19 No.12
In order to improve the electromagnetic shielding rate of Carbon Fiber (CF), it was produced using the nickel nano-powder impregnating method. Using two types of nickel powder having thicknesses of 50μm and 100μm, and a thermoplastic elastomer resin, a compound containing 10-20% nickel content was mixed and then manufactured through an extruder. The CF coated with the compound was woven and manufactured using a 1-ply specimen. The final nickel content of the specimen was verified using TGA and the distribution of nickel powder on the CF surface was verified using SEM. The metal shows a high shielding rate in the low-frequency band, but the shielding rate decreases at higher-frequency bands. The CF improves at the higher frequency band, and metals reflect electromagnetic waves while carbon absorbs electromagnetic waves. The study of shielding materials, which are stronger and lighter than metal, by using CF lighter than metal and enabling the shielding rate from low-frequency band to high-frequency band, confirmed that the larger the area coated with nickel nano-powder, the better the electromagnetic shielding performance. In particular, CF coated with a thickness of 100μm has a shielding rate similar to that of copper and can also be used for EV/HEV automotive cables and other applications in the future.