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일개 농촌지역 노인의 아포지단백 E 다형성과 인지기능 변화
김상규,황태윤,이경수,강복수,조희순,배영경,Kim, Sang-Kyu,Hwang, Tae-Yoon,Lee, Kyeong-Soo,Kang, Pock-Soo,Cho, Hee-Soon,Bae, Young-Kyung 대한예방의학회 2009 예방의학회지 Vol.42 No.4
Objectives : The aim of this study is to examine the cognitive function change related to aging, the incidence of cognitive impairment, and the association between apolipoprotein E polymorphism and cognitive impairment through a follow-up of the elderly with normal cognitive ability at baseline. Methods : Two hundred and fifteen subjects aged 65 and over were surveyed in February, 1998 (baseline survey), and their cognitive function was assessed again in 2003 1st follow-up) and the once again in 2006 (2nd follow-up). Ninety one subjects completed all surveys up through the 2nd follow-up and their cognitive function scores using MMSE-K (Korean Version of the Mini-Mental State Examination) and the distribution of apolipoprotein E allele were analyzed. Results : The cognitive function scores decreased with aging and the difference between baseline and the 2nd follow-up scores of the study increased with the age group. The incidence rate of cognitive impairment through an 8-year follow-up was 38.5% and higher in older age groups. Age was the only significant factor for incidence of cognitive impairment, but there was no significant association between apolipoprotein E genotype and incidence of cognitive impairment. Conclusions : The cognition of the elderly decreased with aging and the association of apolipoprotein E genotype with incidence of cognitive impairment was not significant in this study. To confirm the association between apolipoprotein E polymorphism and incidence of cognitive impairment further studies will be needed.
모든 상부 위장관 간엽 종양(Mesenchymal Cell Tumor)의 침습 접근이 필요한가?
이은주 ( Eun Ju Lee ),김태동 ( Tae Dong Kim ),오현아 ( Heun Ah Oh ),이형철 ( Hyeung Chul Lee ),김준환 ( Jun Hwan Kim ),장병익 ( Byung Ik Jang ),김태년 ( Tae Nyeun Kim ),정문관 ( Moon Kwan Chung ),배영경 ( Young Kyeong Bae ) 대한소화기학회 2005 대한소화기학회지 Vol.45 No.6
Background/Aims: Mesenchymal tumors are the most frequent submucosal tumors in gastrointestinal trail. We reviewed the mesenchymal tumors which are confirmed by pathology to examine whether the invasive approach of all mesenchymal tumors is necessary. Met