위나선균양성 특발성혈소판감소성자반증에서 위나선균박멸요법의 효과: 증례 연구

박치영,문홍섭,Park, Chi-Young,Moon, Hong-Seop 한국임상약학회 2011 한국임상약학회지 Vol.21 No.1

Idiopathic thrombocytopenic purpura is a potentially life-threatening condition characterised by thrombocytopenia and mediated by an autoimmune mechanism. Several recent studies have suggested that an association exists between H. pylori eradication and improvement in platelet count in a significant proportion of patients with idiopathic thrombocytopenic purpura. This study confirmed the efficacy of H. pylori eradication in increasing the platelet count in steroid refractory idiopathic thrombocytopenic purpura patients. Eradication therapy is simple and inexpensive, with limited toxicity and the advantage of avoiding long-term immunosuppressive treatment.

HK-1000 약침이 흰쥐의 고지혈증 및 동맥경화증에 미치는 영향

박치영,홍권의,Park, Chi-Young,Hong, Kwon-Eui 대한약침학회 2008 Journal of pharmacopuncture Vol.11 No.3

Objective&Methods: The purpose of this study is to observe the effects of HK-1000 Herbal-acupuncture solution at GB34(Yangleungchean) on hyperlipidemia and arteriosclerosis in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, urine and liver, as well as the histological change of liver and aorta. Results: 1. HK-1000 herbal-acupuncture infusion increased the cell viability rate, DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. The levels of total cholesterol, free cholesterol, LDL-cholesterol, phospholipid in serum and AI(atherogenic index) were decreased, and the ratio of HDL to TCL(HDL/TCL) and the level of TG in serum were increased as compared with those of the control group. 3. In the HK-1000 group, serum AST and ALT were significantly lower than those of the HG group and saline group. 4. Hepatic GSH and catalase activities were significantly increased as compared with those of the saline group. Conclusions: From the above results, it is suggested that HK-1000 herbal-acupuncture at GB34 has a therapeutic effect on hyperlipidemia and arteriosclerosis.

Dynamic Bond를 이용한 자극감응형 고분자 재료의 최신 연구동향

박치영,정은선,조아라,김경택,Park, Chiyoung,Jeong, Eun Sun,Cho, Arah,Kim, Kyoung Taek 한국고분자학회 2013 고분자 과학과 기술 Vol.24 No.4

고해상도 항공영상을 이용한 주거지역 필지경계 설정에 관한 연구

박치영,이재원,Park, Chiyoung,Lee, Jaeone 한국공간정보학회 2015 한국공간정보학회지 Vol.23 No.1

최근 지적공부상의 다양한 오류를 재정비하여 스마트 지적으로의 도약을 위한 노력의 일환으로 지적재조사사업이 수행되고 있다. 이에 부응하여 본 연구에서는 일반 주거지역을 대상으로 GSD 5cm의 고해상도 항공영상을 활용하여 지상현황과 부합하는 영상기반의 신속한 필지경계 설정방안을 제시하고자 한다. 이의 적용가능성과 정확도를 검토하기 위하여 두 지역을 연구 대상지로 선정하여 지적현황측량 성과와 지적공부상 필지면적을 기준으로 수치도화에 의해 추출된 필지경계점 및 면적의 정확도를 비교 분석하였다. 연구결과 수치도화 방법에 의한 필지경계점 분석의 경우 연구대상지역 모두 "지적측량 시행규칙"에 따른 연결교차의 기준은 만족하였으나 보다 엄격한 기준이 적용된 "지적재조사에 관한 특별법"의 결정 기준 ${\pm}0.07m$에는 모두 벗어나는 결과로 확인되었다. 그리고 면적 분석 결과 허용오차의 범위를 벗어나는 필지가 제천(A 지역)의 경우 총 70개 필지 중 15개로 약 20%, 그리고 수원(B 지역)의 경우 총 19개 필지 중 2개로 약 10%의 비율에 해당된다. 면적 정확도의 허용범위를 벗어나는 필지는 대부분 건물의 지붕이나 처마에 의한 폐색현상과 지상의 경계에 존재하는 수목과 같은 장애물의 영향, 그리고 인공구조물이나 자연적인 지물이 없어 경계의 기준이 모호하여 영상에서 인식이 불가능한 경우임을 알 수 있었다. 따라서 이러한 유형들의 필지경계 설정을 위한 해결책으로 표지용 스티커의 활용방안을 제시하였다. As part of an effort to leap smart cadastre system by doing rearrangement of various mismatches in the land register, the cadastre renovation project is being recently conducted. In response to this demand, this paper proposes an image-based rapid parcel boundary demarcation plan using the high resolution aerial image with a GSD (Ground Sample Distance) of 5cm that matches to real ground boundary situation in residential area. To review the feasibility and accuracy of this proposed methodology, we compared the accuracy of parcel boundary point and parcel area extracted from the digital stereo plotting on the basis of results of cadastral boundary surveying and land register over the selected two test areas. The comparative accuracy result of all boundary points by digital stereo plotting is satisfied with accuracy requirement according to the criteria of the enforcement regulation of cadastral surveying, whereas it exceeded allowable error of ${\pm}0.07m$, more strictly specified in the Special Act on Cadastral Renovation. And about 20% of the total 70 parcels extracted by digital plotting are out of area tolerance in Jecheon study area, and 10% of the total 19 parcels in Suwon study area. The parcels exceeding accuracy limit are mostly due to the occlusion caused by building roof or eaves, and the obstacles such as trees existing on the boundary. Furthermore, an object identification is impossible in image because of vague boundary reference in case of nonexistence of man-made structures or natural features. Therefore, the utilization of boundary identification stickers is recommended as a solution for these types of land parcel.

길경약침(桔梗藥鍼)의 천식억제(喘息抑制) 및 면역조절효과(免疫調節效果)에 대(對)한 실험적(實驗的) 연구(硏究)

박치영,홍권의,Park, Chi-Young,Hong, Kwon-Eui 대한약침학회 2006 Journal of pharmacopuncture Vol.9 No.3

Objectives : The aim of this study was to investigate the effect of Asthma-depression and Immunoregulation with PR-HAS(Herbal-acupuncture with Platycodi Radix infusion solution) infection at Joksamni(St36) on ovalbumin-induced asthma in mice. Methods : C57BL/6 mice were sensitized and challenged with OVA(ovalbumin) for 12 weeks(once a week). The experimental group(OVA-PR-HA) was treated with concentrations(1%) of PR-HAS at Joksamni(St36) for the later 8 weeks(3times/week). The second experimental group(OVA-Needle prick) was treated with Needle-Prick at Joksamni(St36) for the later 8 weeks(3times/week). Results : 1. The weight and total cells in the mice lung treated with PR-HA decreased significantly compared with that of control group. 2. Total leukocytes and eosinophils in BALF of the mice group treated with PR-HA decreased remarkably compared with those of control group. 3. The sticking of collagen on histological analysis of lung sections, the mice group treated with PR-HA decreased significantly compared with those of control group. 4. The concentrations of IL-4, IL-5, IgE in BALF, and IL-4, IL-5, IL-13 in serum of the mice group treated with PR-HA decreased significantly compared with those of control group. 5. The number of Gr-1+/CD11b+ and CD11b+ cells in the lungs of the mice group treated with PR-HA decreased significantly compared with that of control group. 6. The numbers of CCR3+ cells, CD4+ cells and CD8+ cells in the lungs, and CD3e+/CD69+ in the lungs of the mice group treated with PA-HA decreased significantly compared with those of control group. 7. The mRNA expression of ${\beta}$-actin, TNF-${\alpha}$, IL-4, IL-5, IL-13 in the mice group treated with PR-HA with RT-PCR decreased significantly compared with those of control group. Conclusions : These result suggests that Platycodi Radix Herbal-acupuncture at Joksamni(St36) in C57BL/6mice may be an effictive part to OVA-induced asthma in C57BL/6 mice.

자율주행시대의 주차시설 재생을 위한 분류 체계 - 서울 3대 도심 내 공영 주차시설을 대상으로

박치영(Park, Chiyoung) 대한건축학회 2021 대한건축학회 학술발표대회 논문집 Vol.41 No.2

This study aims to derive a hierarchical classification method for the existing parking facilities in large cities. The 5 classification criteria - space, structure, size, use, and accessibility - were derived through a survey and analysis on the existing 205 public parking facilities in Jongno·Jung-gu, Gangnam-gu, and Yeongdeungpo-gu, the major downtown areas of Seoul. This classification method contributes to set the early direction of the existing parking facilities regeneration such as remodeling, reconstruction, and multi-dimensional land use planning.

긍정심리기반 집단미술치료 프로그램에 대한 메타분석

박치영(Chi-young Park), 박은선(Eun-seon Park) 한국미술치료학회 2023 美術治療硏究 Vol.30 No.3

본 연구는 메타분석을 통해 긍정심리기반 집단미술치료에 대한 효과크기를 산출하고 미술치료 중재의 여러 변인에 따른 특성을 파악하여 긍정심리기반 미술치료의 개입 전략과 치료적 지원을 위한 과학적인 이론적 근거를 제공하는데 목적이 있다. 이를 위해 2012년부터 2022년 3월까지 국내에서 발행된 연구를 대상으로 PRISMA 선정기준을 적용하여 31편의 연구를 선정하였으며 CMA(Comprehensive Meta-Analysis) 2.0을 사용하여 메타분석을 실시하였다. 메타분석 결과는 첫째, 무선효과모형을 적용한 긍정심리기반 집단미술치료의 전체효과 크기는 Hedges’s = 4.276으로 큰 효과크기가 나타났다. 둘째, 종속 변인에 대한 효과크기는 스트레스, 사회성 및 문제행동, 정서영역, 자아성장 순으로 나타났으며 집단 간 통계적으로 유의하였다. 셋째, 중재관련 특성 중 조절 변인의 효과크기는 연구대상 유형에 따라 유의하게 나타났으며, 집단의 크기, 회기 수, 회기 시간에 따른 조절효과는 유의하지 않았다. 마지막으로 메타분석에 활용된 대부분의 데이터에서 출판편향이 다소 있으나 전체 연구 결과에 영향을 미치는 정도는 아니라고 할 수 있다. 이러한 연구결과를 바탕으로 본 연구의 의의와 제한점에 대해 논의하였다. The purpose of this study is to calculate the effect size for positive psycho-based group art therapy through meta-analysis and to identify the characteristics of different variables of art therapy interventions to provide a scientific rationale for intervention strategies and therapeutic support for positive psycho-based art therapy. To this end, 31 studies were selected using PRISMA selection criteria for studies published in Korea from 2012 to March 2022, and meta-analysis was conducted using CMA(Comprehensive Meta-Analysis) 2.0. The results of the meta-analysis were as follows: First, the overall effect size of positive psychological-based group art therapy using the random-effects was Hedges's = 4.276 which showed a large effect size. Second, the effect size on dependent variables was in the order of stress, sociality and problem behavior, emotional area and self-growth and it was statistically significant between groups. Third, the effect size of the moderating variable among the characteristics related to the intervention was significant according to the type of the study subject and the moderating effect according to the size of the group, the number of sessions, and the session time was not significant. Finally, most of the data used in the meta-analysis has some publication bias but it does not affect the overall research results. Based on these findings, this study discussed the implications and limitations of the study.

Ticlopidine 복용 후에 발생한 범혈구감소증 2예

박치영 ( Park Chi Yeong ),강지은 ( Kang Ji Eun ),임현성 ( Im Hyeon Seong ),정춘해 ( Jeong Chun Hae ) 대한내과학회 2003 대한내과학회지 증례 특집호 65-5 부록3 Vol.0 No.-

Ticlopidine is an inhibitor of platelet aggregation used in the management and prevention of thromboembolic disorders. Hematological toxicity is one of the most important side effects of ticlopidine, including neutropenia, thrombocytopenia and more seriou

조간대 복원이 수조류의 분포에 미치는 영향

박치영 ( Chi-young Park ),신만석 ( Man-seok Shin ),김호준 ( Ho-joon Kim ),백운기 ( Woon-kee Paek ),이준우 ( Joon-woo Lee ) 한국환경생태학회 2016 한국환경생태학회지 Vol.30 No.5

본 연구는 경기도 시화호를 대상으로 조간대 복원 전(2009~2011년)과 후(2012~2014년)의 조류군집 양상과 이용분포변화를 알아보고자 수행되었다. 조간대 수조류는 복원 후에 약 4만여 개체가 증가하였다. 대부분 수조류가 증가하였으며, 잠수성오리류는 감소하였다. 관찰된 각 수조류의 개체수 증감 변동 분석을 실시한 결과 도요·물떼새류가 복원전과 비교하여 뚜렷한 개체수 증가를 보였다. 서식지 이용양상의 변화는 복원 후에 가장 넓어진 조간대 면적을 포함하고있는 남측간척지 조간대와 내수면 조간대 지역으로서 이는 먹이원인 저서생태계의 변화와 연관된다. 복원된 시화호의 저서생태계는 기회종의 감소와 함께 오염에 민감한 평형종의 지속적인 증가로 안정화가 진행되었고 결과적으로 도요·물떼새류의 서식에 환경적 여건이 개선되었음을 판단할 수 있었다. 결과적으로 조간대의 복원은 수조류의 이용 분포변화에도 단시간에 영향을 주었다. 복원 전과 비교하여 모든 수조류가 넓은 면적의 조간대에 고르게 분포하였으며, 특히 도요·물떼새류와 고니·기러기류의 서식분포에 큰 변화를 준 것으로 확인되었다. 본 연구결과는 조력발전에 의한 인위적인 조간대의 복원이 조류에 미치는 영향 연구로서 수행되었으며, 종다양성 측면에서 조간대의 중요성이 재확인 되었고 현재까지 긍정적인 변화를 보이고 있다. 향후 유사한 환경에서의 생물다양성 유지 및 증진을 위한 대안의 한 방법으로 방향성을 제시할 수 있을 것이다. In this study, the bird fauna of Sihwa Lake in Gyeonggi Province were investigated from 2009 to 2014 to identify the effect of the restored intertidal zone on bird community. Based upon the analysis of the habitat status and distribution change of water birds in the intertidal zone, the following conclusions were obtained. The number of water bird individuals increased by approx. 40 thousand after the restoration. Most of water bird species increased, but diving ducks decreased. Analysis of the number of individuals of water birds before and after the intertidal zone restoration showed that there was a significant increase in the number of shorebird individuals. There is a habitat use pattern change in the southern tideland intertidal zone that includes the largest area of widened intertidal zone and the inland waters of the intertidal zone. This is related to the change of benthic ecosystem which is the food source of birds. The benthic ecosystem in restoring Sihwa Lake has been stabilized with a decrease in opportunistic species and consistent increase in equilibrium species that are sensitive to pollution. As a result, the environmental conditions for shorebirds have been improved. The restoration of intertidal zone affected the habitat use and distribution patterns of water birds in a short period of time. Compared to before restoration, all the water birds now use the wide area of the intertidal zone with no partiality and it is confirmed that the restoration greatly affected the distribution of shorebirds and swan & geese. This study was conduced to identify the effects of an artificial restoration of intertidal zone due to tidal power generation of bird species. In terms of maintaining and improving biodiversity, the intertidal zone restoration was recognized to be important and still shows positive results. This study is expected to provide a direction when an alternative is required to maintain and improve biodiversity in a similar situation in the future.

Dyanmic Bond 를 이용한 자극감응형 고분자 자료의 최신 연구동향

박치영(Chiyong Park),정은선(Eun Sun Jeong),조아라(Arah Cho),김경택(Kyoung Taak Kim) 한국고분자학회 2013 고분자 과학과 기술 Vol.24 No.4