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      • KCI등재

        급성 아세트아닐라이드계 제초제 중독의 임상 분석

        박철상 ( Cheol Sang Park ),이미진 ( Mi Jin Lee ),성수 ( Seong Soo Park ),정원준 ( Won Joon Jeong ),김현진 ( Hyun Jin Kim ) 대한임상독성학회 2011 대한임상독성학회지 Vol.9 No.2

        Purpose: Acetanilide has been in widespread use as an amide herbicide compound. However, available data regarding acute human poisoning is scarce. The aim of this study was to analyze the clinical characteristics of acetanilide poisoning in order to identify the risk factors associated with severity. Methods: We conducted a retrospective observational study encompassing the period January 2005 to December 2010, including adult ED patients suffering from acetanilide intoxication. Toxicological history, symptoms observed, clinical signs of toxicity, and laboratory test results were collected for each patient. The patients were classified into two groups for analysis, according their poisoning severity score (PSS). Resulting clinical data and prognostic variables were compared between mild-to-moderate poisoning (PSS 1/2 grades), and severe poisonings and fatalities (PSS 3/4 grades). Results: There were a total of 37 patients, including 26 alachlor, 6 s-metolachlor, 4 mefenacet, and 1 butachlor cases. The majority of patients (81.1%) were assigned PSS 1/2 grades. Changes in mental status and observation of adverse neurologic symptoms were more common in the PSS 3/4 group. The median ingested volume of amide herbicide compound was 250 ml (IQR 200-300 ml) in the PSS 3/4 group, and 80 ml (IQR 50-138 ml) in the PSS 1/2 group. Also, the median GCS observed in the PSS 3/4 group was 13 (IQR 10-14), which was markedly low as compared to a median GCS of 15 in the PSS 1/2 group. Overall mortality rate was 5.4%, and profound cardiogenic shock was observed prior to death in all fatalities . Conclusion: When compared to previous reports, acute acetanilide poisoning resulted in relatively moderate severity. The presence of neurologic manifestations, hypotension, lower GCS score, and larger ingested volumes was associated with more serious effects and mortalities.

      • SCOPUSKCI등재

        SHS법에 의한 붕화지르코늄의 합성 및 치밀화에 미치는 첨가제의 영향

        이윤복,철상,김상배,김영우,홍채,오기동,Lee, Yun-Bok,Gwak, Cheol-Sang,Kim, Sang-Bae,Kim, Yeong-U,Park, Hong-Chae,O, Gi-Dong 한국재료학회 1998 한국재료학회지 Vol.8 No.7

        ZrO2, B2O3 및 AI을 사용하여 SHS법에 의한 붕화지르코늄을 합성을 하고 산화철과 알루미늄 분말의 첨가가 합성물의 치밀화에 미치는 영향에 대하여 검토하였다. 합성물중에 존재하는 결정상은 대부분이 ZrB2와 $\alpha$-AI2O3상이었다. 산화붕소와 알루미늄의 몰비가 1.0:3.3이상일 때 합성물의 치밀화는 크게 증가하였고, ZrB2 입자도$\alpha$-AI2O3용융상과 더불어 조대하였다. 산화철 1목에 대하여 알루미늄을 1-3몰을 첨가한 것과 산화철 1.5몰에 대하여 알루미늄을 3몰 첨가시 $\alpha$-AI2O3를 중심으로하는 슬라그상으로부터 용융상의 분이가 가능하였고, 이들 용융상에 존재하는 결정상은 ZrB2이외에 Fe, Fe2B, Zr2Fe상이었다. 용융상의 상대밀도는 산화철 1몰에 대하여 알루미늄을 1몰 첨가시 83.2%인 반면에 그 이상의 첨가량에 대해서는 치밀화는 크게 증가하여 알루미늄을 3몰 첨가한 경우 상대밀도는 93.7%로서 최대를 나타내었다.

      • KCI등재후보

        예초기에 의한 안 외상 환자의 임상적 고찰

        강인구 ( In Gu Kang ),박철상 ( Cheol Sang Park ),류현식 ( Hyun Sik Ryu ),허석진 ( Sok Jin Heo ),채연석 ( Youn Sok Chae ),김현진 ( Hyun Jin Kim ),성수 ( Seong Soo Park ),이미진 ( Mi Jin Lee ),정원준 ( Won Joon Jeong ) 대한외상학회 2011 大韓外傷學會誌 Vol.24 No.2

        Purpose: Lawn trimmers are widely used to cut the weeds around graves in South Korea, but they can cause ocular injury. We investigate at the emergency room the incidence and the clinical features of ocular trauma induced by lawn trimmers. Methods: The authors analyzed 106 patients who visited Konyang University Hospital`s emergency room from March 1, 2007, to October 31, 2011, because of ocular trauma caused by a lawn trimmer. Patients were sorted into two groups, severe ocular injury and mild ocular injury, Results: Over a 5-year period, 106 patients with ocular trauma caused by a lawn trimmer underwent clinical study, Most of the patient (103 patients) were males, and the average age of the patients was 51.75±11.66 years, The incidence of ocular trauma peaked in the sixth decade of life. Most injuries occurred between July and September. Severe ocular injury developed in 46.2% of all patients. As age increased, so did the severity of the ocular injury. The impacting object was a small stone in 43.4% of all patients, Nobody wore protective gear, The most common diagnosis were corneal abrasion, followed by intraocular foreign body, corneal laceration, and sclera laceration. Fifty-four patients were followed up, and thirty-six patients of them had severe injury. The most common complication was a traumatic cataract. Conclusion: Ocular trauma induced by a lawn trimmer is more severe than general ocular trauma. We suggest that everyone using a lawn trimmer should wear protective gear and follow safety guidelines.

      • KCI등재

        조레틸 주사 후 의식 변화를 주소로 내원한 환자 1례

        이영기 ( Yeong Ki Lee ),강인구 ( In Gu Kang ),박철상 ( Cheol Sang Park ),허석진 ( Seok Jin Heo ),채연석 ( Youn Seok Chai ),성수 ( Seong Soo Park ),이재광 ( Jae Kwang Lee ),김현진 ( Hyun Jin Kim ),정원준 ( Won Joon Jeong ) 대한임상독성학회 2013 대한임상독성학회지 Vol.11 No.1

        Zoletil is a non-opioid, non-barbiturate animal anesthetic and proprietary combination of two drugs, a dissociative anesthetic drug, tiletamine, with the benzodiazepine anxiolytic drug, zolazepam. Zoletil has greater potency than ketamine. Zoletil is abused for recreational purposes, especially by people with easy access to medicine. However, in Korea, it is available over-the-counter. Here we report on a case of an 83-year-old woman who received injection of seven vials of “Zoletil 50”by her daughter and presented with an altered mental change. Her mental state was stupor and vital sign was hypotension, bradycardia. Her blood tests indicated metabolic and respiratory acidosis and hyperkalemia. She was treated with intravenous naloxone and flumazenil but was not responsive. She was admitted to the ICU and treated with supportive therapy. Her mental state showed transient recovery, however, her clinical manifestation worsened and she expired.

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