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- 저자 : 류현식 ( Hyun Sik Ryu ) (검색결과 3 건)
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주요 수면유도제인 독실라민과 디펜히드라민의 급성 중독 비교
류현식 ( Hyun Sik Ryu ),이미진 ( Mi Jin Lee ),박성수 ( Seong Soo Park ),정원준 ( Won Joon Jeong ),김현진 ( Hyun Jin Kim ) 대한임상독성학회 2010 대한임상독성학회지 Vol.8 No.2
Purpose: The previous studies on H1 antihistamine overdose have generally been limited to cases of acute doxylamine succinate (DS) poisoning, yet there have been some studies on diphenhydramine (DPH) overdosing. But many clinicians consider the two drugs to be very similar and to have similar ingredients. The purpose of this study was to clarify the toxicologic characteristics and clinical outcomes between DS and DPH poisoning/overdose. Methods: We reviewed the medical and intensive care records of the patients with acute DS or DPH poisoning and who admitted to our emergency department from January 2008 and April 2010. We collected patient information regarding the features of the poisoning and the clinical and demographic characteristics. The patients were assessed for the clinical outcomes, the GCS, the PSS (Poisoning Severity Score) and the SOFA (Sequential Organ Failure Assessment). Results: Fifty seven patients (45 cases of DS poisoning and 12 cases of DPH poisoning) were enrolled. Compared with the DS group, the DPH group had higher incidences of intubation, serious mental change, QTc prolongation and ECG conduction abnormality (p=0.041, <0.001, 0.014 and 0.044, respectively). The DPH group had a higher PSS and a longer ICU stay. The peak CPK time and the CPK normalization time were longer for the patients with rhabdomyolysis due to DS poisoning. Conclusion: Two common H1 antihistamines, doxylamine and diphenhydramine, are in the same ethanolaminestructural class, but the toxico-clinical outcomes are different according to many aspects. Therefore, clinicians could take a careful approach for the differential diagnosis and management between DS and DPH poisoning.
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석면 비산 장비를 이용한 토양 중 석면 비산 특성 및 위해성 평가
김인자,김정욱,류현식,정명채,Kim, In Ja,Kim, Jeong-Wook,Ryu, Hyun Sik,Jung, Myung Chae 한국지하수토양환경학회 2012 지하수토양환경 Vol.17 No.5
The objective of this study is to examine a releasable asbestos sampler developed for measuring friable asbestos from soil to air controlled by wind velocity and water contents. Asbestos contaminated soil with 3.75% at the Sinsuk-asbestos mine was sampled, air-dried and sieved to 100 mesh, then homogenized during 24 hours' agitation. Various wind velocities, 1 m/s, 2 m/s, 3 m/s, and 5 m/s, were applied to evaluate releasable characteristics of the releasable asbestos sampler. In addition, soils with 1.0%, 3.4%, 4.4%, 11.0%, 16.2%, and 20.0% of water contents were also examined the amount of friable asbestos by the releasable asbestos sampler. Collected soil and air samples were analyzed by polarized light microscopy (PLM) and phase contrast microscopy (PCM), respectively. Those contents were applied to calculate an excess life cancer risk (ELCR). This study also discussed the relationship with risk assessment by a weeding scenario of activity based sampling (ABS) and field applied releasable asbestos sampler. The result was shown that friability of asbestos in soil increased with wind velocity and decreased with water content. In comparison with ELCR results, over 10E-4 of cancer risk was found in condition on < 5% water content and > 3m/s wind velocity.
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강인구 ( In Gu Kang ),박철상 ( Cheol Sang Park ),류현식 ( Hyun Sik Ryu ),허석진 ( Sok Jin Heo ),채연석 ( Youn Sok Chae ),김현진 ( Hyun Jin Kim ),박성수 ( Seong Soo Park ),이미진 ( Mi Jin Lee ),정원준 ( Won Joon Jeong ) 대한외상학회 2011 大韓外傷學會誌 Vol.24 No.2
Purpose: Lawn trimmers are widely used to cut the weeds around graves in South Korea, but they can cause ocular injury. We investigate at the emergency room the incidence and the clinical features of ocular trauma induced by lawn trimmers. Methods: The authors analyzed 106 patients who visited Konyang University Hospital`s emergency room from March 1, 2007, to October 31, 2011, because of ocular trauma caused by a lawn trimmer. Patients were sorted into two groups, severe ocular injury and mild ocular injury, Results: Over a 5-year period, 106 patients with ocular trauma caused by a lawn trimmer underwent clinical study, Most of the patient (103 patients) were males, and the average age of the patients was 51.75±11.66 years, The incidence of ocular trauma peaked in the sixth decade of life. Most injuries occurred between July and September. Severe ocular injury developed in 46.2% of all patients. As age increased, so did the severity of the ocular injury. The impacting object was a small stone in 43.4% of all patients, Nobody wore protective gear, The most common diagnosis were corneal abrasion, followed by intraocular foreign body, corneal laceration, and sclera laceration. Fifty-four patients were followed up, and thirty-six patients of them had severe injury. The most common complication was a traumatic cataract. Conclusion: Ocular trauma induced by a lawn trimmer is more severe than general ocular trauma. We suggest that everyone using a lawn trimmer should wear protective gear and follow safety guidelines.
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