http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
남해안 패류양식장에서 분리한 Vibrio parahaemolyticus의 병원인자분포 및 항균제내성
박용수 ( Yong Soo Park ),박큰바위 ( Kunbawui Park ),권지영 ( Ji Young Kwon ),유홍식 ( Hong Sik Yu ),이희정 ( Hee Jung Lee ),김지회 ( Ji Hoe Kim ),이태식 ( Tae Seek Lee ),김풍호 ( Poong Ho Kim ) 한국수산과학회(구 한국수산학회) 2016 한국수산과학회지 Vol.49 No.4
From 2013 through 2015, we investigated the contamination status and antimicrobial resistance patterns of pathogenic Vibrio parahaemolyticus in commercially valuable seawater and shellfish (Oyster Crassostrea gigas, short-neck clam Venerupis philippinarum, ark shell Scapharca broughtonii and mussel Mytilus galloprovinciallis) from the southern coast of Korea. The detection rate of V. parahaemolyticus was highest in short-neck clams (23.7%), followed by ark shells (19.2%), oysters (15.9%), mussels (13.6%), and seawater (8.6%). The following percentages of PCR assays of shellfish were positive for the thermostable direct hemolysin-related hemolysin gene (trh) : oysters (12.8%), shortneck clams(11.8%), and ark shells (3.4%). Similar assays for the thermostable direct hemolysin gene (tdh) resulted in positive results for short-neck clams (5.9%) and ark shells (3.4%). Antimicrobial resistance was present in 100% of 8 tdh (+) and 2 trh (+) V. parahaemolyticus isolates challenged with ampicillin. However, all pathogenic V. parahaemolyticus were sensitive to 14 other antibiotics. To ensure the safety of shellfish consumption, the continuous monitoring of the prevalence and distribution of virulence factors of V. parahaemolyticus in shellfish farms is needed.
증례 : 내분비-대사 ; 클라인펠터증후군과 동반된 제2형 당뇨병 1예
박용수 ( Yong Soo Park ),김동선 ( Dong Sun Kim ),윤지영 ( Ji Young Yoon ),안유헌 ( You Hern Ahn ),최웅환 ( Woong Hwan Choi ),김태화 ( Tae Wha Kim ),홍상모 ( Sang Mo Hong ) 대한내과학회 2010 대한내과학회지 Vol.79 No.6
제2형 당뇨병 환자가 경구 혈당강하제로 불규칙적인 치료를 해오던 중 뒤늦게 성선기능저하증이 발견되어 클라인 펠터증후군을 진단받고 테스토스테론 보충요법과 인슐린치료를 시행한 증례로서 당뇨병 및 인슐린저항성과 성호르몬 결핍 간의 밀접한 연관성에 대한 인식을 제고하는 바이다. An increased frequency of diabetes or impaired glucose tolerance in Klinefelter`s syndrome has been previously reported. Insulin resistance is considered to be the cause of this phenomenon in Klinefelter`s syndrome, which is associated with low serum SHBG and sex hormone deficiency. Sex hormone deficiencies also result in dyslipidemia and metabolic syndrome. The interrelationship between diabetes, metabolic syndrome, and androgen deficiency is complex. Here we report a case of an 18-year-old man first diagnosed with diabetes mellitus 3 years ago. Upon physical examination the patient showed characteristic phenotypes compatible with primary hypogonadism. Subsequently, tests aimed at determining the cause of hypogonadism, including a chromosomal analysis, suggested Klinefelter`s syndrome. The patient`s HOMA-IR score was compatible with insulin resistance. Therefore, when diabetes mellitus develops at a young age with characteristic phenotypes, a careful history and physical examination may be needed to determine whether the patient might have primary hypogonadism caused by Klinefelter`s syndrome. (Korean J Med 79:701-704, 2010)
박용수(Yong Soo Park),한훈식(Hun Sik Han),김서영(Seo Young Kim),강상우(Sarng Woo Karng),엄석기(Sukkee Um) 대한기계학회 2011 대한기계학회 춘추학술대회 Vol.2011 No.5
발전/난방/냉방 동시공급의 700 W<SUB>e</SUB>급 가정용 Tri-Gen 시스템 시제품을 개발하였다. 본 시스템은 연료를 발전기에 공급하여 전력을 생성하고 발전기의 배열을 이용하여 난방 및 냉방을 하는 시스템으로 외부전원의 공급 없이 독립적으로 사용할 수 있다. Prime mover 로는 1 ㎾<SUB>e</SUB>, 출력의 스터링 발전기를 채택하였고 배열구동 고체식 제습냉방 장치를 이용하여 냉방을 구현하였다. 발전부, 난방부, 냉방부 및 시스템을 제어하기 위한 전장제어부를 모듈화 설계하고 이를 시스템 통합하여 700 W<SUB>e</SUB>,급 Stirling Tri-Gen 시스템을 완성하였다. A 700 W<SUB>e</SUB> household Tri-Gen system which simultaneously produces electricity, heating and cooling from a single energy unit is developed. The Tri-Gen system generates electricity from a power generator with fuel consumption and harnesses the waste heat resulting from electric generation for heating and cooling. This is designed as a standalone system which operates in the absence of any external power supply. A Stirling Engine of 1 ㎾<SUB>e</SUB> power output is adopted as a prime mover and cold air is supplied by using a heat-driven desiccant cooler. A modular design for a power generator, a heating unit, a cooling unit and a system control unit is performed and each subsystem is integrated into the Stirling Tri-Gen system
박용수(Yong Soo Park),송영기(Young Kee Shong),송영욱(Yeong Wook Song),김성연(Seong Yeon Kim),이홍규(Hong Kyu Lee),고창순(Chang Soon Koh),민헌기(Hun Ki MIn) 대한내과학회 1989 대한내과학회지 Vol.36 No.5
N/A Hypothyroidism and hyperthyroidism are both associated with a variety of muscle abnormalities, from myalgia to myopathy. There are several reports of autoimmune thyroiditis associated with various rheumatic disorders, such as systemic sclerosis. Polymyositis, however, has been reported in very few cases, if any, especially after the treatment for active hyperthyroidism. A 22-year-old woman developed idiopathic polymyositis during the treatment of Graves' disease with propylthiouracil. She developed severe proximal muscle weakness during the treatment for hyperthyroidism. Her serum creatine kinase level was elevated. Electromyography, muscle biopsy and the clinical course of the patient's illness were consistent with idiopathic polymyositis. Whether this coexistence of Graves' disease and polymyositis represents a cause-effect association or a chance occurrence is unknown.
곰피 추출물이 난소를 절제한 흰쥐의 혈액 유동성 및 혈중 지질함량에 미치는 영향
Young Kyoung Kim(김영경),Min Hee Jeon(전민희),Yong Soo Park(박용수),Hyun Jung Hwang(황현정),Sang-Hyeon Lee(이상현),Sung Gu Kim(김성구),Yuck Young Kim(김육용),Mihyang Kim(김미향) 한국생명과학회 2010 생명과학회지 Vol.20 No.12
갱년기의 여성에는 여러 폐경 증후들이 나타나는데, 특히 estrogen의 감소로 인한 혈중 지질 조성의 변화 등으로 심혈관계 질환의 발병율이 높아지게 된다. 본 연구에서는 실험동물로써 흰쥐를 이용하여 인위적으로 갱년기를 유도한 후 갈조류인 곰피 추출물의 영향을 혈중지질 농도, 혈소판 응집력 및 혈액 유동성을 통하여 그 효과를 검토하고자 하였다. 그 결과 갱년기유도로 인하여 증가된 혈청 중 중성지방 및 총콜레스테롤 함량은 곰피 추출물 투여에 의해 저하되었으며, 특히 곰피 추출물 200 ㎎/㎏ bw/day 투여는 중성지방 함량을 유의적으로 감소시키는 결과를 나타내었다. Ldl-콜레스테롤, 동맥경화지수(AI) 및 심혈관위험지수(CRF) 또한 곰피 추출물 투여에 의해 저하되었다 한편 Hdl-콜레스테롤 농도는 난소절제에 의해 감소하였으나, 곰피 추출물을 투여에 의해 증가되었다. 혈액의 유동성에 곰피 추출물의 효과를 실험한 결과 난소 절제에 의해 혈액의 점도가 증가하여 유동성이 저하되었으나, 곰피 추출물 투여로 인해 유동성이 향상됨을 알 수 있었다. 또한 난소 절제에 의해 혈소판 응집능이 증가하였으나, 곰피 추출물 투여로 인해 완화되는 효과를 볼 수 있었다. 이상의 결과로부터 갱년기에 나타날 수 있는 혈중 지질 변화에 대하여 곰피 추출물이 지질 및 혈행 개선 효과를 나타내었으며, 특히 곰피 추출물 200 ㎎/㎏ bw/day 투여는 모든 항목에서 유의성 있는 결과를 나타내어 곰피가 심혈관 관련성 질환 예방에 도움을 줄 것으로 기대된다. Estrogen deficiency in peri- and postmenopausal women results in variety of neurovegetative, psychic and somatic symptoms, and may contribute to severe diseases within the aged female population. Ecklonia stolonifera (ES) is an edible brown algae traditionally used in fishery towns in Far East Asia. This study was performed to investigate the effects of ES extracts on blood flow and serum lipid concentration in ovariectomized rats. Weight-matched female Sprague-Dawley strain rats were assigned to four groups. Three groups were surgically ovariectomized (OVX). The fourth group was sham operated. Rats were randomly assigned to the following groups: sham-operated rats (Sham), ovariectomized control rats (OVX-CON), ovariectomized rats supplemented with ES extract at 50 ㎎/㎏ bw/day (OVX-ES50) and ovariectomized rats supplemented with ES extract at 200 ㎎/㎏ bw/day (OVX-ES200). Serum total cholesterol and triglyceride contents decreased in the sham group compared to the OVX-CON group. Six weeks feeding of ES extract resulted in a significant (p<0.05) lowering of serum triglyceride and a lowering tendency of total cholesterol level. The level of Hdl-cholesterol in serum increased by supplementation of ES extracts at 50 ㎎/㎏ and 200 ㎎/㎏ bw/day (p<0.05). Blood passage time of the ES extracts-supplemented group was higher than the OVX-CON group. The ability of platelet aggregation of groups treated with ES extracts was less than that of the OVX-CON group. These results suggest that the beneficial effects of ES extract may be used to possibly improve on the metabolic syndrome of menopausal women.