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RISS 인기검색어
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- 저자 : 민승기(Seung Gee Min) (검색결과 5 건)
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김수태(Soo Tae Kim),김건표(Keon Pyo Kim),정승용(Seung Yong Jeong),한세환(Se Hwan Han),민승기(Seung Gee Min),정중기(Joong Ki Chung),이건욱(Kuhn Uk Lee),이효석(Hyo suk Lee),오용석(Yong Seok Oh),이상형(Sang Hyung Lee),김현집(Hyon Jip Ki 대한소화기학회 1995 대한소화기학회지 Vol.27 No.6
Partial resection of liver is the standard treatment modality in hepatocellular carcinoma(HCC). But the resection of liver is impossible in large HCC, especially with the cirrhotic liver. An alternative treatment for such patients would be orthotopic liver transplantation. We experienced a case of liver transplantation for HCC patient with far advanced disease. The patient had no clinical evidence of distant metastasis preoperatively. We did liver transplantation from a donor who was diagnosed as brain death due to traffic accident. The blood type was compatible and operation was finished successfully. Immunosuppressive treatment with cyclosporine was done and the recipient was known to have hepatitis B. Hepatitis B immune globulin was administered. Immediate postoperative recovery was uneventful but the failure in the of alpha-fetoprotein to normal level was observed. Multiple hot uptake of bone was detected on the bone scan during the follow up and the recipient was expired after 7 months. (Korean J Gastroenterol 1995;27:744 - 748)
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버거씨병 환자의 혈청에서 항혈관내피세포항체 발현도 분석
김상준,민승기,허승,안문상,정중기 대한혈관외과학회 2000 Vascular Specialist International Vol.16 No.1
Purpose: The pathogenesis of Buerger's disease is unknown and only smoking is considered as an important factor of the occurrence and recurrence of the disease. The development of antiendothelial cell antibody (AECA), a kind of autoantibody against the vascular endothelium, is recognized as a common serological feature in several diseases characterized by immune-mediated vascular damage. The purpose of this study is whether AECAs develop in the sera of pahents of Buerger's disease or not and, if develop, to find what relationship exists between the status of the disease and the degtee of AECA expression. Methads: Twenty sera were obtained from 15 patients with Buerger's disease, and 11 from 11 healthy male smokers as controls. Additionally 5 sera from nonsmoking females and 4 from nonsmoking males were tested, Among 5 out of 15 Buerger's disease patients, the blood samples were obtained twice. Statistically there was no age difference between patients and controls. Human umbilical cord vein endothelial cells (HUVEC) were eultured and used as the target of AECA. The expression of AECA was measured with enzyme-linked immunosorbent assay (ELISA) and anti-human peroxidase conjugated goat IgG was used as a secondary antibody. Results: The value of whole patients group 666±60 vs. controls 88±10, there was statistically significant (P $lt;0,05); a group of active disease status 797±61 vs. remission 423±60, higher in active group (P$lt;0.05); smokers in patients 732±73 vs. quit-smokers 544±94, higher in smokers, but not significant; na difference was observed between healthy females and males regardless of smoking history. Conclusion: The AECA seems to be closely related with Buergers disease and the measurement of AECA expression with ELISA may be considered as a useful tool for the diagnosis of Buerger's disease and as a helpful predictor of occurrence and relapse of the disease.
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말초동맥 폐쇄질환에서 유로키나제(Urokinase)의 선택적 동맥주입법에 의한 혈전 용해 치료
김상준,박재형,정진욱,민승기 대한혈관외과학회 1993 Vascular Specialist International Vol.9 No.1
Acute thrombotic occlusion of peripheral vessels(native or graft) remains a major challenge for the vascular surgeons. To evaluate the role of selective intra-arterial urokinase thrombolytic therapy in peripheral arterial occlusive disease, the results of 24 therapies performed in 22 patients from October 1987 to May 1993 were reviewed. Among the 24 cases, the causes of occlusion were thrombosis due to chronic arterial occlusive disease in 19 cases, angiography-related thrombosis in 2, and heart-origin thromboembolism in 2. Thirteen patients underwent 13 therapies for native arterial occlusion and 9 patients un- derwent 11 therapies for graft vessel occlusion. Complete success occurred in 9 cases(37.5%)- complete clot lysis with no additional procedure,' Partial success occurred in 5 cases(20.3%) complete clot lysis, but requiring percutaneous transluminal angioplasty or surgery for underlying stenosis which was found after clot lysis; Failure occurred in 10 of 24 therapy(41.7%) incomplete clot lysis or occurance of complication requiring emergency operation. The overall success rate was 58.3%. The l year patency rate of the successful cases was 92%. There were 4 major complications(17%), such as hemorrhage, clot migration and catheter thrombosis, which were treated by emergency operation. These data show that selective intra-arterial urokinase thrombolytic therapy in the treatment of peripheral arterial occlusive disease can be used as primary therapy, and also as adjunctive therapy before PTA or surgery to get some information about angiographic vascular anatomy, including possible cause of thrombosis such as stenosis amenable to PTA or surgery.
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