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위험 요인이 없는 젊은 여성에서 발생한 육종양 간세포암 1예
남효성 ( Hyo Sung Nam ),김해경 ( Hae Kyung Kim ),마세웅 ( Sae Ung Ma ),유병현 ( Byung Hyun Yu ),정기명 ( Ki Myung Jung ),공경택 ( Kyung Taek Gong ),이용주 ( Yong Ju Lee ),박태일 ( Tae Il Park ),허병원 ( Byung Won Hu ),박신희 ( Shi 대한소화기학회 2006 대한소화기학회지 Vol.47 No.6
A previously healthy 22-year-old woman was admitted with a complaint of right upper quadrant abdominal pain for 2 weeks. Her past history was not remarkable. On admission, HBsAg and anti-HCV were negative and a-FP was within normal range. Abdominal sonography and CT showed a mass in Liver measuring 10×11 cm with features of central necrosis and hemorrhage. On 6th hospital day, hemoperitoneum developed suddenly. She underwent emergency Laparotomy and trisegmentectomy. Intraoperative finding revealed a hemoperitoneum with a tumor filled with liquefied necrotic tissues. Microscopically, the tumor was mostly composed of pleomorphic spindle cells with abundant anastomosing vascular channels and partly composed of tumor cells with trabecular arrangement. On immunohistochemical staining, tumor cells reacted with cytokeratin and vimentin, while CD34 and hepatocyte staining revealed negative. She died 2 months after the operation. We report a case of rapidly deteriorated primary sarcomatoid hepatocellular carcinoma in a young female without any risk factor. (Korean J Gastroenterol 2006;47:458-462)
유병현 ( Byung Hyun Yu ),마세웅 ( Se Woong Ma ),남효성 ( Hyo Sung Nam ),정기명 ( Kee Myoung Jung ),지상철 ( Sang Chul Jee ),김정욱 ( Jeoung Ouk Kim ),이용주 ( Yong Ju Lee ) 대한내과학회 2007 대한내과학회지 Vol.73 No.3
저자들은 우안의 맥락막 흑색종으로 안구적출술을 시행했던 60세 남자가 11년 후 상복부 통증을 주소로 입원하여 위내시경 및 조직생검과 그리고 복부 전산화 단층촬영 및 간의 흡인침생검으로 확인된 전이성 악성 흑색종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Malignant melanoma is a common malignancy that has potential to metastasize to any site. Metastatic disease involving the stomach and liver are difficult clinical problem and presenting symptoms include weight loss, fatigue, and nonspecific epigastric pain. Laboratory results, barium X-ray study, endoscopy, CT, arteriography, and MRI suggest a metastatic malignant melnoma of the stomach and liver. The diagnosis may be confirmed by endoscopic biopsy of the stomach and aspiration needle biopsy of the liver. Metastatic melanoma is generally incurable, with survival in patients with visceral metastases generally <1 year. A case is reported of a metastatic malignant melanoma of the stomach and liver in a 60-year-old male patient, that was discovered 11 years after an enucleation of a choroidal melanoma of the right eye.(Korean J Med 73:311-316, 2007)