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유병현 ( Byung Hyun Yu ),마세웅 ( Se Woong Ma ),남효성 ( Hyo Sung Nam ),정기명 ( Kee Myoung Jung ),지상철 ( Sang Chul Jee ),김정욱 ( Jeoung Ouk Kim ),이용주 ( Yong Ju Lee ) 대한내과학회 2007 대한내과학회지 Vol.73 No.3
저자들은 우안의 맥락막 흑색종으로 안구적출술을 시행했던 60세 남자가 11년 후 상복부 통증을 주소로 입원하여 위내시경 및 조직생검과 그리고 복부 전산화 단층촬영 및 간의 흡인침생검으로 확인된 전이성 악성 흑색종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Malignant melanoma is a common malignancy that has potential to metastasize to any site. Metastatic disease involving the stomach and liver are difficult clinical problem and presenting symptoms include weight loss, fatigue, and nonspecific epigastric pain. Laboratory results, barium X-ray study, endoscopy, CT, arteriography, and MRI suggest a metastatic malignant melnoma of the stomach and liver. The diagnosis may be confirmed by endoscopic biopsy of the stomach and aspiration needle biopsy of the liver. Metastatic melanoma is generally incurable, with survival in patients with visceral metastases generally <1 year. A case is reported of a metastatic malignant melanoma of the stomach and liver in a 60-year-old male patient, that was discovered 11 years after an enucleation of a choroidal melanoma of the right eye.(Korean J Med 73:311-316, 2007)
증례 : 호산구성 위장관염을 동반한 재발성 위 이형성증 1예
지상철 ( Sang Chul Jee ),김해경 ( Hae Kyung Kim ),공경택 ( Kyoung Taeg Kong ),이용주 ( Yong Ju Lee ),정기명 ( Kee Myoung Jung ),김정욱 ( Jeong Ouk Kim ),김태현 ( Tae Hyun Kim ) 대한내과학회 2007 대한내과학회지 Vol.73 No.5
저자들은 호산구성 위장관염을 동반한 재발성 위 이형성증 환자에서 내시경 점막 절제술과 스테로이드 투여로 호전된 1예를 경험하였기에 이를 문헌고찰과 함께 보고한다. The association of malignant tumors and peripheral eosinophilia or tissue eosinophilic infiltration has been uncommonly described. Moreover, a recent study has demonstrated some gastric cancers can express eosinophilic chemotactic factor. Interestingly, we recently experienced a case of recurrent eosinophilic gastroenteritis with relapsing gastric dysplasia. It is suggested that gastric dysplasia can also produce eosinophilic chemotactic factors and eosinophilic gastroenteritis can develop with recurred dysplasia. In this patient, eosinophilia served as an indicator of disease activity or as a marker. Eosinophilia may represent an important disease marker with prognostic significance and may rarely cause disease on its own.(Korean J Med 73:530-534, 2007)
재생불량성빈혈로 오인될 정도로 심한 범혈구감소증을 동반한 폐결핵 1예 (증례)
정기명 외 중앙대학교 의과대학 의학연구소 2007 中央醫大誌 Vol.32 No.1/2
Prevalence rate of pulmonary tuberculosis has been decreasing in Korea. But, newly diagnosed pulmonary tuberculosis in young people is increasing nowadays in Korea. Therefore diagnosis and treatment of tuberculosis are very important in Korea. Pancytopenia is one of the characteristics of hematological changes in tuberculosis. Authors experienced a rare case of pancytopenia associated with pulmonary tuberculosis in a young female. In this case, the clinical features and initial laboratory data looked like aplastic anemia. The bone marrow examination showed hypocellularity which looked like aplastic anemia. But, after the beginning of anti-tuberculosis chemotherapy and active supportive care, clinical symptoms and signs improved and the pancytopenia resolved. Tuberculosis is a common infection in Korea. Therefore, when pancytopenia is present, together with hepatopathy and pyrexia, tuberculosis should always be considered.