증례 : 혈액종양; 동종조혈모세포 이식 후 기관지 내에서 재발한 급성 골수성 백혈병 1예

나수진 ( Soo Jin Na ),이현정 ( Hyeon Jung Lee ),하직환 ( Jick Hwan Ha ),김승준 ( Seung Joon Kim ),김태정 ( Tae Jung Kim ),김희제 ( Hee Je Kim ),강지영 ( Ji Young Kang ) 대한내과학회 2013 대한내과학회지 Vol.85 No.3

다수의 경우 골수성 육종은 진단 내리기 쉽지 않고 감염 이나 다른 고형 종양으로 오진하기 쉽다. 특히 이전에 혈액질환의 기왕력이 없는 경우는 더욱 그러하다. 임상의들은 고형 종괴에 대해 검사를 진행함에 있어서 진단이 명확치 않은 경우 드문 질환이긴 하지만 골수성 육종의 가능성을 염두 하여야 하며 조직 검사를 통한 진단을 위해 노력을 기울여야 할 것이다. 이전 혈액 질환의 기왕력이 없던 환자에서 골수성 육종이 진단되었을 경우에는 동반되어 있을지 모르는 혈액 질환에 대한 조사가 동반되어야 한다. 또한 이전 완전 관해를 이루었던 환자에서 골수 외 재발이 확인되었을경우에는 골수 외 재발이 골수 재발과 동반되거나 선행하여 나타날 수 있으므로 골수에서의 재발 여부에 대한 평가도 다시 이루어져야 할 것이다. Myeloid sarcoma is an uncommon extramedullary tumor of immature myeloid cells or myeloblasts. It may occur alone or concurrently with an underlying hematological malignancy. Although it can develop anywhere in the body, common sites include bones, particularly the skull and vertebra, soft tissues, and lymph nodes. However, there have been few reports of myeloid sarcoma occurring in the respiratory system, especially the large airways. We describe a case of endobronchial relapse of acute myeloid leukemia in a patient who achieved complete remission after allogeneic stem cell transplantation. To our knowledge, this is the first such report in Korea. (Korean J Med 2013;85:318-323)

증례 : 순환기 ; 제1형 신경섬유종증 환자에서 나타난 폐고혈압 1예

나수진 ( Soo Jin Na ),이혜연 ( Hye Yeon Lee ),김현선 ( Hyun Seon Kim ),성현진 ( Hyeon Jin Seong ),전부석 ( Bu Seok Jeon ),전희경 ( Hui Kyung Jeon ) 대한내과학회 2013 대한내과학회지 Vol.85 No.5

신경섬유종증과 관련된 폐고혈압은 심각한 기능적, 혈역 학적 장애를 초래할 수 있다. 따라서 신경섬유종증 환자에서 호흡곤란, 기절, 피로 등 폐고혈압의 증상이나 징후가 나타 난다면 임상의들은 가능한 조기에 심초음파 등의 검사를 하여 폐고혈압을 발견하고 치료를 시작할 수 있도록 해야 한다. 또한 신경섬유종증과 관련된 폐고혈압의 병태생리적 이해를 위해 체계적이고 규모 있는 연구가 필요하며 이를 바탕으로 생존율 향상에 도움이 되는 추가적인 치료법에 대한 논의가 이루어져야 할 것이다. Neurofibromatosis type I is a genetic disease caused by mutations in the neurofibromin 1 (NF1) gene. Although it is characterized by a number of distinct clinical features, including cafe au lait macules, freckling in the axillary or inguinal regions, neurofibromas, and Lisch nodules (iris harmartomas), it can affect all physiological systems in the body [1]. Neurofibromatosis-related pulmonary hypertension has also been reported, and some patients showed a poor prognosis despite having received proper medical treatment [2-4]. We herein describe a case of pulmonary hypertension in a patient with neurofibromatosis type I who had no identified risk factors of pulmonary hypertension. To our knowledge, this is the first such report in Korea. (Korean J Med 2013;85:521-525)

좌심실 수축 기능 보전 심부전증의 치료

나수진 ( Soo Jin Na ),백상홍 ( Sang Hong Baek ) 대한내과학회 2015 대한내과학회지 Vol.88 No.2

More than 50% of patients who are diagnosed with heart failure have preserved ejection fraction (HFpEF), and they have an equally poor prognosis when compared to patients with heart failure with reduced ejection fraction (HFrEF). However, a comprehensive understanding and awareness of heart failure with preserved ejection fraction is still limited and there are currently no optimized treatments to improve morbidity and mortality in these patients. This review summarizes the differences in the epidemiology, pathophysiology, diagnosis, and prognosis between HFpEF and HFrEF. We also review current management strategies of HFpEF patients according to evidence-based treatment guidelines. (Korean J Med 2015;88:135-141)

몸의 확장성과 섹슈얼리티 이미지 연구

나수진 ( Soo Jin Na ) 한국무용예술학회 2012 무용예술학연구 Vol.35 No.-

This article aims to figure out what roles the body plays in generating and interpreting sexual images and what the characteristics of the body are in the intervention to it. However, unlike the reality that sexual images are excessive, theoretical approaches to the proper understanding of sexuality or the expressive methods of it still lack, and particularly, the study on ‘the body’ centering around sexual images is very rare; thus, this study not only analyzes actual works but conducts theoretical tasks, too. Therefore, this study largely consists of theoretical discussion about what the sexuality is and how it works and the analytic process to figure out the body’s roles in the process of generating sexual images and acquiring meaning through movies and dance works. In the theoretical discussion, this paper introduces the concept and theory of sexuality. Based on that, this study divides sexuality by its functions into the common sexuality which extends and reproduces the ruling discourse of the society, evolving sexuality which expresses resistant discourse, and the mixed sexuality which either coexists or is interpreted totally differently. These are adopted as the actual criteria to analyze the works. In the analysis process, this paper analyzes three movies, 「Original Sin」, 「Tomb Raider」, and 「Girls’ Night Out」, and three dance works, 「Romeo and Juliet」, 「Carmen」, and「Groosland」to figure out how they produce the diverse sexual images expressed in them and how they take meaning in the association with the body. In this process, it was found that sexual images are generated not just by the actor’s or the actress’ body and the dancer’s body but by organic harmony with various objets appearing on the screen or stage such as costume or props, too. This study views the characteristics of the body organically harmonized with surrounding environment as ‘extensibility’. Also, the fact that as the objects of expansion are more, it is easier to interpret the images and as it gets fewer, the symbolic meaning becomes stronger and it is harder to interpret them means that the body’s extensibility is not just the source of sexual images but the passage of interpretation as well. Thus, it can be said that the fact that sexual images are generated and interpreted around the ‘extensibility’ of the body provides constant directivity to the creator’s position about how to realize sexual images and also provides information to the receptor’s position about how to interpret the sexual image. In other words, it can be said that the body’s extensibility provides ways for dance art centering around the body to communicate with people.

유틸리티 절감을 위한 미반응 스티렌 모노머 회수공정의 설계

봉주영 ( Jooyoung Bong ),나수진 ( Sujin Na ),이광순 ( Kwang Soon Lee ) 한국화학공학회 2017 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.55 No.1

ABS 중합공정 중 잔류 모노머 회수 공정의 유틸리티 사용량 절감을 위한 공정의 개선을 수행하였다. ABS 폴리머생산 과정 중 잔류 모노머 회수 공정은 제품의 품질 향상을 위해 반드시 필요하다. 잔류 모노머의 회수를 위한 다양한 방식이 있으나, 본 연구에서 대상으로 한 것은 스팀 스트리핑 공정이다. 기존의 스팀 스트리핑은 많은 양의 스팀과 냉각수가 사용되고 있으나, 본 연구를 통해 유틸리티 사용을 절감하는 새로운 방안을 찾고자 하였다. 스트리핑 후 모노머와 함께 배출되는 스팀의 잠열을 진공상태의 수증기로 회수하고, 압축으로 온도를 상승시켜 스트리핑 스팀으로 재사용하도록 함으로써 스팀의 사용을 획기적으로 절감하였다. 또한 모노머 최종 회수 과정에서 발생되는 물을 모노머응축에 냉각수로 활용함으로써 용수에 대한 사용량도 감소 시킬 수 있었다. A study for process design to curtail the utility consumption during residual styrene monomer recovery in an ABS polymerization process was carried out. Among different techniques for residual monomer recovery, the steam stripping is dominantly employed in industries. The existing process, however, consumes a large amount of utility (steam and cooling water), and this study focused on the design of a new process that can substantially spare the utility consumption. A new process was configured to utilize the latent heat of the stripping steam, which is condensed with the monomer using cooling water after exiting the stripper. The condenser was modified to use vacuum state water as coolant and to generate vacuum state steam using the latent heat of the stripping steam. The steam is injected to the stripper as the stripping steam after upgrading using a compressor. Through this modification, consumption of steam and also cooling water could be significantly reduced at some expense of electricity for compressor operation.

소셜네트워크 빅데이터를 활용한 체육계, 학교 운동부, 운동부 지도자 미투 키워드 분석

백승헌(Baek, Seung Heon),나수진(Na, Su Jin) 한국체육교육학회 2021 한국체육교육학회지 Vol.26 No.1

본 연구는 쇼셜네트워크 빅데이터 분석을 통해 체육계, 운동부, 지도자 미투 키워드의 잠재변수 파악 및 현실적 대안 제시를 목적으로 한다. 연구 방법은 텍스톰(Textom)의 텍스트 마이닝(Textmining)을 활용해 키워드를 정제한 후 Ucinet6 프로그램의 CONCOR 분석을 통해 키워드를 시각화하였다. 연구결과는 ‘체육계 미투’ 군집은 1개의 주요인식과 4개의 주변인식으로 ‘학교 운동부 미투’ 군집은 1개의 주요인식과 5개의 주변인식으로 ‘운동부 지도자 미투’ 군집은 1개의 주요인식과 4개의 주변인식으로 범주가 도출되었다. 추출된 키워드 분석을 통해 학교 운동부와 프로 스포츠로 이어지는 체육계의 폐쇄적 구조 시스템에 경종을 울리고, 운동선수와 지도자의 왜곡된 인권과 성 의식을 바로잡는데 연구의 의미가 있다. Purpose: The purpose of this study is to identify the potential variables of the following keywords the sports field, school athletics, school athletic instructors, Me Too through analysis of social network big data to present practical alternatives. Methods: For the purpose of the research Textom"s Textmining was conducted. Results: The ‘School Sports Me Too" cluster consists of 1 main recognition and 4 peripheral perceptions. The ‘School Sports Me Too" cluster consists of 1 main recognition and 5 peripheral perceptions. The "Exercise Leader Me Too" cluster consists of 1 major recognition and 4 peripheral perceptions. Conclusion: Through the extracted keyword analysis, meaningful awareness can be derived to correct distorted human rights and gender consciousness within sports athletics.

심근 조직 재생을 위한 3차원 혈관화 된 심근 패치 개발

장진아(Jinah Jang),박훈준(Hun Jun Park),나수진(Soo Jin Na),김석원(Seok-Won Kim),김희진(Hee Jin Kim),박주영(Ju Young Park),김현지(Hyeon Ji Kim),박문녀(Moon Nyeo Park),최승현(Seung Hyun Choi),박선화(Sun Hwa Park),김성원(Sung Won Kim),권 대한기계학회 2015 대한기계학회 춘추학술대회 Vol.2015 No.11

Monoclonal Gammopathy of Undetermined Significance가 동반된 강직성 척추염 환자에서 발생한 AA형 및 AL형 심아밀로이드증

김우현 ( Woohyeon Kim ),김선아 ( Seon A Kim ),윤경진 ( Kyung Jin Yun ),나수진 ( Soo Jin Na ),현지인 ( Ji In Hyun ),정정임 ( Jung Im Jung ),곽승기 ( Seung Ki Kwok ),박성환 ( Sung Hwan Park ) 대한류마티스학회 2014 대한류마티스학회지 Vol.21 No.3

심아밀로이드증의 궁극적 치료는 아밀로이드 침착의 병인에 달려 있으므로 증상치료와 함께 초기에 아밀로이드증의 원인을 밝히는 것이 무엇보다 중요하다. 강직성 척추염에서 AA형 아밀로이드증이 심장을 침범하는 경우는 흔치 않으며, 특히 본 증례는 동반질환인 MGUS와 연관된 AL형 심아밀로이드증이 심장 조직검사를 통해 함께 진단되어 치료를 시행한 경우로, 이와 같은 예는 국내 보고된 사례가 없어 저자들이 경험한 1예를 문헌고찰과 함께 보고한다. Amyloidosis is a clinical disorder caused by extracellular deposition of proteinaceous insoluble fibrils in various tissues, resulting in organ compromise. Amyloid L (AL) amyloidosis is the most common type of systemic amyloidosis, which occurs in association with multiple myeloma or monoclonal gammopathy of undetermined significance (MGUS). Secondary amyloid A (AA) amyloidosis is a complication of chronic inflammatory conditions, such as rheumatoid arthritis or ankylosing spondylitis. We report a case of a 49-year-old manwith a 11-year history of ankylosing spondylitis, who was recently diagnosed with MGUS presented with cardiac amyloidosis of both the AA and AL types. We report this case along with a review of relevant literature.

증례 : 순환기 ; 성인에서 폐동맥판협착과 난원공개존증을 동반한 동맥관개존증 1예

김선아 ( Seon A Kim ),허성호 ( Sung Ho Her ),박만원 ( Mahn Won Park ),나수진 ( Soo Jin Na ),김형덕 ( Hyung Duk Kim ),김지은 ( Ji Eun Kim ),김우현 ( Woo Hyeon Kim ) 대한내과학회 2013 대한내과학회지 Vol.85 No.4

저자들은 중증 폐동맥판협착과 난원공개존증이 있음에도 동맥관개존증이 동반되어 무증상으로 나타난 성인에서의 증례를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다. Pulmonary valve stenosis (PS) is the 3rd most common form of adult congenital heart disease. The patient was a 56-year-old woman, with known congenital heart disease but who was not receiving any treatment as she was not functionally limited. A two-dimensional echocardiogram showed severe right ventricular hypertrophy, pulmonary valve thickening and systolic doming. A color Doppler revealed a retrograde flow from the aorta to the left pulmonary artery. She had severe heart failure on the right hand side from a PS but did not display any symptoms. We hypothesized that she had a retrograde flow to the pulmonary circulation through a patent ductus arteriosus (PDA), through which oxygenated blood could be supplied to the systemic circulation and, hence, no hypoxia. We attempted a balloon valvuloplasty for the PS followed by a device closure for the PDA. Here we report on this adult female with severe PS but lacking any symptoms, due to the presence of a PDA. (Korean J Med 2013;85:406-410)

Background/Aims: The point mutations in 23S rRNA gene accounts for the majority of the clarithromycin resistance of Helicobacterpylori. This study aimed to investigate the association between the clarithromycin-resistance of H. pylori and the failure of p

남관우 ( Kwan Woo Nam ),백명기 ( Myong Ki Baeg ),권정현 ( Jung Hyun Kwon ),조성훈 ( Soung Hoon Cho ),나수진 ( Soo Jin Na ),최명규 ( Myung Gyu Choi ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.5

tissue lymphoma. This study was to determine whether H. pylori was associated with colorectal neoplasms in Korean subjects undergoing routine checkup. Methods: A total of 10,082 subjects underwent routine checkups from January 2004 to April 2005. A H. pylori IgG test and stool occult blood test were included in the routine checkup program. Colonoscopy was performed if the stool occult blood test was positive or under subject request. Patients who underwent colonoscopy and had histologically confirmed cases of colorectal neoplasms were designanted as the subject group and those without as the control group. Results: Of the 10,082 subjects, 597 had full colonoscopy. The results identified 9 colorectal carcinomas and 118 adenomas. H. pylori seropositivity was identified in 6 (66%) subjects with colorectal carcinoma, 81 (68.6%) with colorectal adenoma and 248 (52.8%) controls. Subjects having colorectal neoplasms had a significantly higher H. pylori seropositivity rate compared with the controls (OR 1.94, 95% CI 1.28-2.95). This remained significant after adjusting for age, sex, body mass index, HbA1c and total cholesterol (OR 1.90, 95% CI 1.23-2.93). Patients with distal neoplasms also had a significantly higher H. pylori seroposivity rate (OR 1.88, 95% CI 1.17-3.01) which persisted after multivariate adjustment (OR 1.79, 95% CI 1.10-2.94). Conclusions: Subjects with colorectal neoplasms present an increased H. pylori seroprevalence compared with controls. (Korean J Gastroenterol 2013;61:259-264)