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김종혁 ( Kim Jong Hyeog ),노영준 ( No Yeong Jun ),김지연 ( Kim Ji Yeon ),문성용 ( Mun Seong Yong ),김현우 ( Kim Hyeon U ),김진건 ( Kim Jin Geon ),이정훈 ( Lee Jeong Hun ),노지호 ( No Ji Ho ),천병철 ( Cheon Byeong Cheol ),이관행 ( 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.3
Mitochondrial myopathies are diseases caused by defects in metabolic pathway of mitochondria. Mitochondrial myopathy is known as one of the causes of recurrent myoglobinuria, while clinically, rarely causes acute renal failure requiring medical treatments. We report a case of rhabdomyolysis and acute renal failure associated with mitochondrial myopathy. A 58-year-old male was presented with dyspnea and hypotensive shock. The patient had a history of recurrent dark colored urine and cramping leg pain after prolonged fasting. Laboratory findings showed hyperkalemia, azotemia, metabolic acidosis, and elevated AST, ALT, and creatinine kinase. He had no history of trauma or medication. Muscle biopsy showed ragged red fibers in modified Gomori staining. On electron microscope, increased number of mitochondria and abnormal mitochondria were seen. He received hemodialysis and his renal function recovered after 1 month. (Korean J Nephrol 2004;23(3):509-513)
신동훈 ( Sin Dong Hun ),김종혁 ( Kim Jong Hyeog ),김지연 ( Kim Ji Yeon ),노영준 ( No Yeong Jun ),문성용 ( Mun Seong Yong ),김진건 ( Kim Jin Geon ),김현우 ( Kim Hyeon U ),이정훈 ( Lee Jeong Hun ),이서진 ( Lee Seo Jin ),김연수 ( Kim 대한신장학회 2003 Kidney Research and Clinical Practice Vol.22 No.5
We report an unusual case of adult minimal change nephrotic syndrome relapsed after 15-year of complete remission. In this case, the disease had occurred to the patient for the first time when he was 52 years old; relatively high age, and had been remitted with steroid therapy. After 15 years of complete remission, he visited our hospital with the symptoms of the generalized edema and the pitting edema of both lower extremities that occurred 15 days ago. Massive proteinuria(15,865 ㎎/day) and hypoalbuminemia(1.7 g/㎗) were detected. The pathologic evaluation of the biopsied specimen of the kidney showed he global sclerosis in 19% of glomeruli in light microscopic finding and the fusion of epithelial foo processes in electron microscopic finding. He was treated with pulse steroid therapy(methylprednisolone 500 ㎎/day iv for 3 days) and then, with oral prednisolone (60 ㎎/day). Generalized edema and proteinuria disappeared after 14 days of treatment, and there has been no relapse ever since. Adult-onset minimal change nephrotic syndrome relapses within 4 years after complete remission in 90% of relapsed patients. The relapse after more than 5 years of complete remission, like this case, is very rare, especially in he case of late-onset disease. However, the possibility of relapse of the minimal change nephrotic syndrome after several years of its remission should be considered constantly and the long-term follow-up more than 10 years may be needed. (Korean J Nephrol 2003;22(5):608-611)
잣뽕나무버섯과 곤봉뽕나무버섯의 생태학적 및 생리학적 특성
김진건 ( Jin-gun Kim ),이화용 ( Hwa-yong Lee ),박용우 ( Yong-woo Park ),이희수 ( Hee-su Lee ),구창덕 ( Chang-duck Koo ) 한국균학회 2018 韓國菌學會誌 Vol.46 No.3
Armillaria is a white-rot fungus that decomposes organics; it is also a root pathogen that kills trees. Recently, since the forest tending practice, the incidence of Armillaria infections on tree stumps has been increasing. Herein, we have examined the morphological features of Armillaria solidipes and A. gallica collected from 10 areas in Korea, and investigated the activities of the decomposing enzymes cellulase and laccase of these two Armillaria species. A. solidipes was found in eight host tree species including Pinus densiflora , Quercus serrata , and Castanea crenata at the altitude of 107~1,396 m, while A. gallica was found in three host species including P. densiflora and Fraxinus rhynchophylla at the altitude of 119~556 m. The fruiting bodies of A. solidipes are close with lamellae, and have brown to black hairs on the stipe, while those of A. gallica are distant with lamellae and clavate-shaped, and have yellow hairs on the base. The activites of cellulase of the two species were not different, but the activity of A. solidipes laccase was higher (12.94 ± 0.4 U/mL) than that of A. gallica laccase (9.14 ± 0.3 U/mL).
증례 : 급성 췌장염 환자에서 복강동맥 협착과 동반하여 발생한 비장경색의 1예
김진건 ( Jin Gun Kim ),임동혁 ( Dong Hyuck Lim ),한봉준 ( Bong Jun Han ),표승일 ( Seung Il Pyo ),이숭환 ( Soong Hwan Lee ),김인숙 ( In Sook Kim ),전의용 ( Eui Yong Jeon ) 대한내과학회 2006 대한내과학회지 Vol.71 No.2
비장경색이 급성 췌장염의 합병증으로 발생된 보고는 드물며, 아직까지 복강동맥 협착과 연관되어 비장경색이 발생된 보고는 없다. 췌장염에서 비장 경색의 발생은 비장 혈관의 혈전에 의한 폐색에 의한 것으로 알려졌다. 그러나 급성 췌장염(특히 두부) 환자에서 비장색을 동반한 경우 가능한 원인으로 복강동맥 협착을 고려해 봐야 할 것이다. 본 증례에서 비장경색의 기전으로 협착후방 확장부의 혈전 형성, 혹은 췌장 두부 동맥으로부터 비장 동맥으로의 비정상적 역류에 의한 것으로 생각된다. 저자들은 급성 췌장염의 병력을 가진 환자에서 혈관조영 술상 발견된 무증상 복강동맥 협착이 비장경색과 연관 되는 1예를 경험하였기에 보고하는 바이다. Prevalence of splenic infarction developed during acute pancreatitis is extremely rare. However, we recently experienced a case of 42-year-old woman who developed splenic infarction during acute alcoholic pancreatitis. There were sustained subjective symptoms and no resolution of image despite of conservative management, so we performed angiography to confirm whether vascular lesion existed or not. We found the significant celiac artery stenosis due to compression by median arcuate ligament and no visible thrombus. We report an unusual case of splenic infarction developed during acute recurrent pancreatitis possibly related with celiac artery stenosis.(Korean J Med 71:198-202, 2006)