뇌조조영술 후 발생한 양측 활차신경마비 1예

김근해,윤숙현,김숙영,Keun Hae Kim,MD,PhD,Sook Hyun Yoon,MD,Sook Young Kim,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.1

Purpose: To report a case of bilateral trochlear nerve palsy following cisternography. Case summary: A 43-year-old male with intermittent watery rhinorrhea persisting for 3 months visited the neurosurgery department of our institute. His past medical history included removal of a pituitary adenoma 22 years prior to presentation. Cerebrospinal fluid leakage was suspected and cisternography was performed. The patient was referred to our ophthalmology department for diplopia 3 days after the cisternography. An alternate prism cover test showed 5 prism diopter (PD) right hypertrophia in the primary position, and underaction of bilateral superior oblique muscles and overaction of the left inferior oblique muscle. A positive Bielschowsky test with the head tilted to either side was observed and excyclotorsion was 9° on the double Maddox rod test. The patient was diagnosed with bilateral trochlear nerve palsy. After 2 years of follow- up, diplopia persisted and recession of the bilateral inferior oblique muscles was performed. After the surgery, diplopia disappeared, the fundus photography showed no excyclotorsion, and the double Maddox rod test indicated 3° of excyclotorsion. Conclusions: Cisternography should be carefully performed due to the possibility of bilateral trochlear nerve palsy, an extremely rare but possible occurrence following the procedure. J Korean Ophthalmol Soc 2014;55(1):155-160

배양된 사람 코점막 섬유아세포에 대한 마이토마이신 C와 5-플루오로우라실의 효과

김근해,김인택,Keun Hae Kim,In Taek Kim 대한안과학회 2011 대한안과학회지 Vol.52 No.2

Purpose: To investigate the effects of two antimetabolites, mitomycin C (MMC) and 5-fluorouracil (5-FU), on proliferation of cultured human nasal mucosa fibroblasts. Methods: Human nasal mucosa fibroblasts were primarily cultured, and exposed to various concentrations of MMC and 5-FU for 5 minutes. Control fibroblasts were exposed to only DMEM media without the drugs. Effect of drugs on cell morphology was observed by phase-contrast microscopy. Cell viability and apoptosis were measured using MTT [3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyl-tetrazolium bromide] assay and Acridine orange/Hoechst (AO/HO) staining, respectively. Results: In both experimental groups exposed to MMC and 5-FU, fibroblasts maintained standard spindle shape. The MTT assay showed that both MMC and 5-FU inhibited fibroblast proliferation in a dose dependent manner. AO/HO staining showed apoptotic cells in both experimental groups. Conclusions: Both MMC and 5-FU have an antiproliferative effect on fibroblasts in vitro at least through induction of apoptosis. Therefore, adjuvant use of either MMC or 5-FU during endonasal dacryocystorhinostomy may improve the clinical outcome by inhibiting proliferation of the nasal mucosa. J Korean Ophthalmol Soc 2011;52(2):233-240

사시 수술 중 근부착부의 위치 변화

김근해,김숙영,Keun Hae Kim,Sook Young Kim 대한안과학회 2006 대한안과학회지 Vol.47 No.1

Purpose: To study how far the insertion site of the extraocular muscle is displaced during strabismus surgery. Methods: We studied 69 eyes of 36 patients for concomitant exodeviation. The distance between the center of the extraocular muscle insertion site and the nearest posterior limbus was measured before and after detaching the lateral rectus muscle. After fixating the insertion stump with forceps, the distance between the same points was measured. Results: The distance between the limbus and the insertion site was measured as 6.54±0.65 mm before detaching the lateral rectus, 6.39±0.65 mm after detaching the muscle from the insertion, and 6.30±0.64 mm fixation of the insertion stump with forceps. Therefore, the muscle insertion site became displaced by 0.15±0.18 mm anteriorly from its original site after disinserting the muscle, and displaced anteriorly by a total of 0.25±0.22 mm after fixating the insertion stump with forceps. Differences in the distance at each stage were statistically significant (p<0.01, paired t-test). Conclusions: The insertion site of the lateral rectus muscle may be displaced anteriorly after disinserting the muscle and fixating the insertion stump with forceps. Therefore, the probability of error in strabismus surgery should be considered.

조직문화, 조직몰입, 직무만족의 관계에 대한 종단연구

김근해 ( Geun Hae Kim ),유성모 ( Seong Mo Yoo ) 국제뇌교육종합대학원대학교 뇌교육연구소 2014 뇌교육연구 Vol.14 No.-

이 연구는 직무만족에 영향을 미치는 변수를 파악하여 급변하는 시장상황에 맞추어 차별화된 직무만족 향상을 위한 기업교육 프로그램의 방향성을 제시하는 것이 목적이 다. 이를 위해 보다 광범위하고 동태적인 기초자료를 제공하고자 2007년, 2009년, 2011년 3개년도의 인적자본기업패널 데이터를 분석하였다. 분석결과, 2007년의 경우 직무만족에 영향을 끼치는 변수로는 조직문화, 기업규모, 조직몰입, HR전담부서유무 순 서로 나타났고, 2009년도는 조직문화, 조직몰입, 기업규모, HR전담부서유무 순서로 나타났으며, 2011 년도는 조직문화, 조직몰입, 기업규모, HR전담부서유무 순서로 나타났다. 이를 통하여 연도에 관계없이 직무만족에 영향을 미치는 공통적인 변수는 조직문화, 조직몰입, 기업규모, HR전담부서유무임을 발견하였다. 이 연구결과를 토대로 향후 직무 만족 향상을 위한 기업교육 프로그램의 주요내용은 조직문화와 조직몰입임을 제시하였으며 기업 내부적으로는 HR전담부서가 필요하며 특히 기업규모가 작을수록 HR전담부서 의 필요성을 부각하였다. This study aims to understand the variables affecting job satisfaction and propose a direction of a corporate training program for the differentiated improvement of job satisfaction for rapidly changing market conditions. For this purpose, to provide broader and more dynamic basic data, it analyzed human capital corporate panel data for three years, 2007, 2009 and 2011. As a result of the analysis, in 2007, the variables affecting job satisfaction were in the order of organizational culture, business scale, organizational commitment, exclusive HR organization; in 2009, in the order of organizational culture, organizational commitment, business scale and exclusive HR organization; and in 2011, in the order of organizational culture, organizational commitment, business scale and exclusive HR organization. Through this, it was found that the common variables affecting job satisfaction regardless of the year include organizational culture, organizational commitment, business scale and exclusive HR organization. Based on the results of the study, it was suggested that the main contents of the corporate training program for the improvement of job satisfaction in the future should be organizational culture and organizational commitment, and that an exclusive in-company HR organization would be necessary, and it was brought into relief that especially, businesses with a smaller scale should have an exclusive H R department.

고등학교 영어교과서 쓰기활동분석: 학년별 연계성과 국가영어능력평가문항 비교를 중심으로

김근해 ( Geun Hae Kim ),박은수 ( Eun Soo Park ) 경북대학교 중등교육연구소 2013 중등교육연구 Vol.61 No.3

본 연구에서는 학습자들이 고등학교 3년 동안 사용하는 영어 교과서 2종, 총 6권을 선택하여 쓰기 활동유형이 학년에 따라 단계적으로 구성되어 있는지 그 연계성을 조사하였다. 그리고 교과서에서 제시하고 있는 쓰기활동유형과 국가영어능력평가시험 쓰기 문항과 비교하여 고등학교 영어교과서가 국가영어능력평가시험(NEAT)의 대비서로서 그 역할을 수행할 수 있는지도 살펴보았다. 분석결과, 각 교과서에서 제시하고 있는 전체 쓰기활동의 수에서 A교과서는 51활동, B교과서는 72활동으로 교과서에 따라 차이가 있었다. 교과서의 쓰기활동은 통제 작문, 유도 작문, 자유 작문으로 구성되어 있으나 학년별 심화단계에 따라 그 비율이 구성되어 있지 않았으며 세부항목별 쓰기활동유형 또한 제한적으로 제시되어 있어서 다양한 글쓰기 활동을 하기에는 미흡하였다. 마지막으로 교과서에서 제시되고 있는 쓰기활동은 국가영어능력평가시험 쓰기문항과의 소재별 연계성이 부족하여 학생들이 국가능력평가시험을 대비하기 위해서는 보완이 필요하다고 하겠다. 쓰기교육이 교실수업에서 효과적으로 이루어지기 위해서는 교과서의 쓰기 단계에 따른 학년별 연계성 마련과 다양한 소재의 쓰기활동 유형 개발에 관한 후속연구가 필요하다. The purpose of this study was to analyze the writing activities of high school English textbooks in terms of connectivity through the grade levels and to compare with the NEAT(National English Ability Test) writing tests in order to examine whether the textbooks are appropriately designed to prepare the NEAT writing tests. Six high school textbooks were selected and analyzed by the number and frequency of writing activities of the English textbooks from controlled to free writing. The findings were as follows: first, the numbers of writing activities presented in the writing parts of the textbook A and B were 51 and 72. The controlled to free writing types were presented in both textbooks but were not balanced through the grade levels. Second, the connectivity between the NEAT and the types of writing in the textbooks showed that the textbooks should be designed to help students to develop their writing skills by practicing the types of writings throughout the grade levels and to provide students similar writing activities to prepare for the NEAT by studying their textbooks.

테논낭 섬유아세포의 증식에 대한 NO의 역할

김근해 ( Keun Hae Kim ) , 김재우 ( Jae Woo Kim ) 대한안과학회 2003 대한안과학회지 Vol.44 No.7

셀룰러 오토마타 모델을 이용한 교차로 시뮬레이션 구현

김근해(Guen-Hae Kim),고상기(Sang-Ki Ko),한요섭(Yo-Sub Han) 한국정보과학회 2014 한국정보과학회 학술발표논문집 Vol.2014 No.6

Gelrite가 배양된 섬유아세포의 증식에 미치는 효과

김재우 ( Jae Woo Kim ) , 김근해 ( Keun Hae Kim ) , 진용헌 ( Yong Hun Jin ) 대한안과학회 2003 대한안과학회지 Vol.44 No.2

의안 장기착용자에서의 의안 관리

김현연,김근해 대한안과학회 2019 대한안과학회지 Vol.60 No.3

목적: 1년 이상 의안을 착용하고 있는 무안구증환자에서 무안구증 눈과 정상 눈을 비교하여 의안 관리에 도움을 주고자 하였다. 대상과 방법: 한눈 안구제거술 및 안와충전물삽입술 후 1년 이상 의안을 착용한 총 40명을 대상으로 무안구증 40안과 정상 40안에 대해 의무기록을 후향적으로 분석하였다. 성별, 나이, 눈물점 이상 여부, 토끼눈, 눈 분비물의 상태, 눈물띠 높이, 위눈꺼풀결막의 상태, 마이봄샘 기능부전 동반 여부, 쉬르머검사, 눈물소관관류술, 진단적 더듬자검사, 의안착용기간, 의안 제거 빈도 결과에 대해 조사하고 의안을 착용하는 무안구증 눈을 정상 눈과 비교하였다. 결과: 의안을 착용하는 무안구증 눈은 토끼눈이 있는 군이 그렇지 않은 군에 비하여 눈의 분비물이 생기는 빈도가 더 많았으며(p=0.04), 의안을 자주 제거하는 군이 그렇지 않은 군에 비하여 눈의 분비물이 생기는 빈도가 더 많았다(p=0.04). 토끼눈의 동반 여부, 의안 제거 빈도는 눈물띠 높이, 쉬르머검사, 눈물소관관류술 결과와는 큰 연관성이 없었다(0.174<p<0.971). 결론: 의안 제거 빈도와 토끼눈의 동반 여부가 무안구증 눈의 분비물 발생과 연관 있는 것으로 나타났으며, 눈의 분비물 발생과 관련하여 매달 이상의 잦은 빈도로 의안을 제거하는 것은 추천되지 않는다. Purpose: To aid in the prosthesis care by comparing anophthalmic eyes with normal eyes in anophthalmic patients wearing prosthetic eyes for more than 1 year. Methods: We retrospectively reviewed the medical records of 40 anophthalmic eyes and 40 normal fellow eyes of 40 patients who wore prosthetic eyes for more than 1 year after unilateral eye removal and orbital implant insertion. We compared data obtained from medical records on sex, age, punctal abnormality, lagophthalmos, eye discharge characteristics, tear meniscus height, upper eyelid palpebral conjunctiva, Meibomian gland dysfunction, Schirmer’s test, lacrimal irrigation test, diagnostic probing, period of wearing the prosthetic eye, and frequency of prosthesis removal between anophthalmic eyes wearing a prosthesis and normal eyes. Results: Anophthalmic eyes with lagophthalmos wearing a prosthesis had a higher frequency of eye discharge than eyes without lagophthalmos (p = 0.04). Eyes with frequent prosthesis removal had a higher frequency of eye discharge than eyes with less frequent prosthesis removal (p = 0.04). However, lagophthalmos and prosthesis removal frequency were not associated with tear meniscus height, or the results of Schirmer’s test, or the lacrimal irrigation test (0.174 < p < 0.971). Conclusions: The frequency of prosthesis removal and presence of lagophthalmos can affect the discharge of anophthalmic eyes. It is advisable not to remove the prosthesis more than once a month to minimize eye discharge.

국소마취하 눈꺼풀처짐 교정수술 중 발생하는 안구심반사

강현구,김근해.Hyun-Gu Kang. M.D.. Keun-Hae Kim. M.D. 대한안과학회 2008 대한안과학회지 Vol.49 No.1

Purpose: To evaluate the incidence and examine the development of oculocardiac reflex during ptosis operation under local anesthesia. Methods: Twenty-eight patients (52 eyes) who underwent ptosis operation under local anesthesia participated in this prospective study. We examined the change of heart rate. We also investigated the incidence of oculocardiac reflex and analyzed factors associated with it. Results: The mean preoperative heart rate was 76.06±11.24 beats/min. During local anesthetic injection, skin incision, traction of the central fat pad, traction of the medial fat pad, traction of the levator palpebrae muscle, the mean heart rates were 74.81±12.64 beats/min, 74.73±12.20 beats/min, 73.63±11.73 beats/min, 73.35±12.24 beats/min, 71.44±11.93 beats/min respectively. Hence, the mean heart rate decreased during each successive part of the operation. The oculocardiac reflex was positive in 24 (46.2%) of 52 eyes. There was no significant difference between the incidence of oculocardiac reflex in males and females. The incidence of oculocardiac reflex was highest during traction of the levator palpebrae muscle. Conclusions: During ptosis operation under local anesthesia, oculocardiac reflex can occur. Gentle manipulation of surgical tissues and cardiac monitoring is needed to prevent side effects from oculocardiac reflex.