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보상 커패시터가 없는 All-Metal IH 구현을 위한 Full-Half Bridge 제어 방안
권만재(Man Jae Kwon),이주승(Joo Seung Lee),강승현(Seung Hyun Kang),황윤성(Yun Seong Hwang),장은수(Eunsu Jang),이병국(Byoung Kuk Lee) 전력전자학회 2021 전력전자학술대회 논문집 Vol.2021 No.11
본 논문에서는 공진 인덕터 및 공진 커패시터 절체 회로 없이 용기 재질에 무관한 가열이 가능한 All-Metal IH(Induction Heating) 시스템의 FB/HB (Full/Half-Bridge) 제어 방안을 제시한다. 단일 커패시터 및 워킹 코일 조건에서도 추가적인 전력 stage 없이 All-Metal IH 구현이 가능한 공진 네티워크 설계를 수행하고 용기 조건에 따른 등가 파라미터 및 토폴로지에 따른 분석 결과 기반의 FB/HB 제어 방안을 제안한다. PSIM 시뮬레이션을 통해 설계사항 및 제안한 제어 방법에 대한 동작 성능을 평가함으로써 이의 타당성을 검증한다.
18β-Glycyrrhetinic acid가 lipopolysaccharide에 의한 생쥐 뇌조직의 염증성 사이토카인과 해마신경세포 자연사에 미치는 영향
이지승,권만재,권수현,김지호,문지영,조윤정,신정원,이종수,손낙원,Lee, Ji-Seung,Kwon, Man-Jae,Kweon, Su-Hyeon,Kim, Jeeho,Moon, Ji-Young,Cho, Yoon-Cheong,Shin, Jung-Won,Lee, Jong-Soo,Sohn, Nak-Won 대한본초학회 2016 大韓本草學會誌 Vol.31 No.6
Objectives : $18{\beta}$-Glycyrrhetinic acid (18betaGA) is an metabolite of glycyrrhizin in Glycyrrhiza (licorice). The present study investigated anti-inflammatory and anti-apoptosis effect of 18betaGA on the brain tissue of lipopolysaccharide (LPS)-treated C57BL/6 mice. Methods : 18betaGA was administered orally with low (30 mg/kg) and high (100 mg/kg) doses for 3 days prior to LPS (3 mg/kg) injection. Pro-inflammatory cytokines mRNA including tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin (IL)-$1{\beta}$, IL-6, and inflammatory enzyme cyclooxygenase-2 (COX-2) mRNA were measured in the cerebral cortex, hippocampus, and hypothalamus tissue using real-time polymerase chain reaction at 24 h after the LPS injection. Histological changes of Cornu ammonis area 1 (CA1) neurons, Bax, Bcl-2, and caspase-3 expression in the hippocampus was also evaluated by immunohistochemistry and Western blotting method. Results : 18betaGA significantly attenuated the up-regulation of TNF-${\alpha}$, IL-$1{\beta}$, IL-6 mRNA, and COX-2 mRNA expression in the brain tissues induced by the LPS injection. 18betaGA also significantly attenuated the reductions of the thickness of CA1 and the number of CA1 neurons. The up-regulation of Bax protein expression in the hippocampal tissue by the LPS injection was significantly attenuated, while the ratio of Bcl-2/Bax expression was increased by 18betaGA treatment. 18betaGA also significantly attenuated the up-regulation of Bax and caspase-3 expression in the CA1 of the hippocampus. Conclusion : This results indicate that 18betaGA has anti-inflammatory and anti-apoptosis effect under neuroinflammation induced by the LPS injection and suggest that 18betaGA may be a beneficial drug for various brain diseases accompanied with the brain tissue inflammation.
국내 오염부지 조사 개선을 위한 US EPA 스마트 스코핑 기술 소개
김보민,김한석,권만재,조호영,Kim, Bomin,Kim, Han-Suk,Kwon, Man Jae,Jo, Ho Young 한국지하수토양환경학회 2020 지하수토양환경 Vol.25 No.2
This paper introduces the 'Smart Scoping for Environmental Investigations Technical Guide' issued by the US Environmental Protection Agency in 2018, which describes the use of smart scoping during lifecycle of remedial investigation projects. This paper also briefly summarizes the guidelines of soil and groundwater contamination investigation of South Korea. The smart scoping practices can support the development of a robust and realistic conceptual site model that is very useful for investigations and evaluations of the contaminated site. The application of evaluation tools relevant for the site-specific characteristics is important for the development of a conceptual site model. The smart scoping recommends the use of previous investigation data and implementation of best proven strategies for successful remedial investigation project. The use of smart scoping in contaminated site investigation will provide better management of contaminated sites.
오염부지 최적 개념모델 수립을 위한 전략적 샘플링 기법 소개
박현지,김한석,윤성택,조호영,권만재,Park, Hyun Ji,Kim, Han-Suk,Yun, Seong-Taek,Jo, Ho Young,Kwon, Man Jae 한국지하수토양환경학회 2020 지하수토양환경 Vol.25 No.2
Even though a systematic sampling approach is very crucial in both the general and detailed investigation phases to produce the best conceptual site model for contaminated sites, the concept is not yet established in South Korea. The U.S. Environmental Protection Agency (EPA) issued the 'Strategic Sampling Approaches Technical guide' in 2018 to help environmental professionals choose which sampling approaches may be needed and most effective for given site conditions. The EPA guide broadly defines strategic sampling as the application of focused data collection across targeted areas of the conceptual site model (CSM) to provide the appropriate amount and type of information needed for decision-making. These strategic sampling approaches can prevent the essential data from missing, minimize the uncertainty of projects and secure the data which are necessary for the important site-decisions. Furthermore, these provide collaborative data sets through the life cycle phases of projects, which can generate more positive proofs on the site-decisions. The strategic sampling approaches can be divided by site conditions. This technical guide categorized it into eight conditions; High-resolution site characterization in unconsolidated environments, High-resolution site characterization in fractured sedimentary rock environments, Incremental sampling, Contaminant source definition, Passive groundwater sampling, Passive sampling for surface water and sediment, Groundwater to surface water interaction, and Vapor intrusion. This commentary paper introduces specific sampling methods based on site conditions when the strategic sampling approaches are applied.