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갑상선절제술을 받은 여성 환자의 공기역학 검사변수 조사
강영애(Young Ae Kang),권인선(In Sun Kwon),원호륜(Ho-Ryun Won),장재원(Jae Won Chang),구본석(Bon Seok Koo) 한국음성학회 2020 말소리와 음성과학 Vol.12 No.2
갑상선 수술 후 음성변화를 보이는 경우가 흔하며 신경손상의 성대마비부터 심인성 음성장애까지 그 증상은 복합적이고 다양하다. 대부분 자연적으로 회복을 보이지만 환자에게 회복시점에 대한 자세한 정보가 부족하다. 호흡은 음성을 만드는 동력이면서 동시에 후두 기능과 효율에 대한 조절자 역할을 하는데, 갑상선 암 수술의 전신마취 부작용으로 호흡기능 부조화를 유발할 수 있다. 이에 본 연구에서는 갑상선 수술 전후 공기역학적 검사결과를 추적하여 갑상선 수술 후 음성회복에 실제적이고 보완적인 정보를 제공하고자 한다. 2014년 5월부터 2015년 7월까지 갑상선 유두암으로 진단받고 수술 받은 환자를 대상으로 술전 1주일, 술후1개월, 술후3개월에 공기역학 검사를 실시하였다. 성대마비, 보청기 착용자, 항우울증약 복용자, 호흡기 질환자, 뇌졸중 병력자 및 임신 대상자는 제외시켜 최종 34명을 대상자로 선정하였다. 공기역학 검사는 PAS 기계를 사용하였고 분석변수는 총 29개이며, 시간요인에 따른 최고호기류율(p=0.004), 평균음도(p<0.01), 호기류지속시간(p=0.001), 호기량(p=0.018) 변수가 통계적으로 유의미한 차이를 보였다. 이때 시간요인의 대응비교에서 최고호기류율과 평균음도 변수는 술전-술후1개월, 술전-술후3개월 간 차이를 보였고, 호기류지속시간과 호기량 변수는 술전-술후3개월, 술후1개월-술후3개월 간 차이를 보였다. 시간과 수술범위의 교호작용 효과는 호기량 (p=0.024) 변수에서만 유의하였다. 갑상선절제술을 받은 여성군에서 최고호기류율과 평균음도 변수의 차이가 있으며 이는 수술 후 호흡훈련의 필요성이 있으며 호기류지속시간과 호기량 변수의 변화는 수술 후 긍정적 생활습관의 반영으로 여겨진다. Breathing is the voice"s driving force and also acts as a regulator of larynx function and efficiency. Respiratory distress is a side effect of general anesthesia in thyroid surgery. Therefore, this study"s objective was to provide practical and complementary information for voice recovery after thyroid surgery, based on aerodynamic evaluation pre- and post-thyroidectomy. From May 2014 to July 2015, aerodynamic evaluations were performed on 34 female patients diagnosed with thyroid papillary cancer one week before surgery (PRE), one month after surgery (P1), and three months after surgery (P3). The Phonatory Aerodynamic System (model 6600, KayPENTAX, USA) was employed for this purpose, and a total of 29 analysis parameters were selected. The results showed statistically significant differences in peak expiratory airflow (p=0.004), mean pitch (p<0.01), expiration airflow duration (p=0.001), and expiratory volume (p=0.018), based on time factors. In the comparison of time factors, peak expiratory airflow and mean pitch parameters were different in PRE-P1 and PRE-P3. Expiration airflow duration and expiratory volume parameters were different in PRE-P3 and P1-P3. The interaction effect of time and surgical range was significant only for expiratory volume (p=0.024). Female patients who undergo thyroidectomy require post-operative breathing training, and exhalation improvement is considered to reflect a positive lifestyle after surgery.
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강영애(Kang, Young Ae),지성주(Jee, Sung Ju),구본석(Koo, Bon Seok),조철우(Jo, Cheolwoo) 한국음성학회 2017 말소리와 음성과학 Vol.9 No.3
The present study aimed to investigate the changes of acoustic parameters of the aspirated voice in stroke patients. The eighty-eight subjects diagnosed with cerebro-vascular accident were divided into 32 penetration/aspiration (P/A) and 56 Non-P/A groups according to the videofluroscopic swallowing study (VFSS) results, and 26 control subjects participated. All subjects preformed VFSS and vowel /a/ was recorded three times pre- and post VFSS. Since the variation in the acoustic parameters within a single phonation has been observed, we proposed a delta formula for the acoustic parameters which can reflect the temporal changes of the each parameter in an utterance. We measured from the voice data eight acoustic parameters: fundamental frequency (F0), standard deviation of F0 (F0_SD), Jitter, relative average perturbation (RAP), Shimmer, amplitude perturbation quotient (APQ), harmonic to noise ration (HNR), noise to harmonic ratio (NHR). Then we found parameters which show the meaningful biggest temporal change in an utterance using the suggested delta parameter. Among them, the deltas of shimmer and APQ were significantly different pre- and post VFSS. These deltas of the P/A and the control group were increased after VFSS, while those of the Non-P/A group was descended. The variation patterns of the P/A and the control group were similar but the change width of the P/A group was larger. The large variations in an aspirated phonation of the P/A group are thought to be caused by irregular changes in air resistance due to residual food on the vocal cords.
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강영애(Kang, Young Ae),구본석(Koo, Bon Seok) 한국음성학회 2015 말소리와 음성과학 Vol.7 No.4
Voice complication without the laryngeal nerve injury can occur after thyroidectomy. The purpose of this study is to investigate voice changes according to extent of thyroidectomy with acoustic analysis. Thirty-five female patients with papillary thyroid carcinoma took voice evaluation at before and 1 month, and 3 months after thyroidectomy. Acoustic analysis parameters were speaking fundamental frequency(SFF), min F0, max F0, dynamic range F0, jitter, shimmer, noise-to-harmonic ratio(NHR), and Cepstral prominence peak(CPP). Repeated-measured analysis of variance was applied. Time-related voice changes showed significant differences in all parameters except NHR. At 1 month after surgery, voice quality was worse and pitch was decreasing, but voice quality and pitch were improving at 3-month follow-up. Voice changes according to the extent of surgery were in SFF, max F0, and dynamic range F0. Time by surgery-related voice change existed only in min F0. The result showed that the severity of voice complication depended on the extend of thyroidectomy which had a negative impact on F0-related parameters. The deterioration of voice quality at 1 month after thyroidectomy may be affected by the loss of thyroid hormone in the blood. The descent of F0-related parameters may be impacted by laryngeal fixation of surgical site adhesion.
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강영애(Kang, Young Ae),구본석(Koo, Bon Seok) 한국음성학회 2015 말소리와 음성과학 Vol.7 No.2
The objectives of this study are to research the frequency of depression symptom in patients with voice disorders and to investigate parameters associated with depression from voice evaluation. A hundred ninety six patients(106 males and 90 females) who had been diagnosed with voice disorders first in their lifetime were selected. All the patients were examined by laryngeal stroboscopy. For depression and voice study, personal interview, acoustic and aerodynamic analysis, voice handicap index(VHI), reflux symptom index(RSI), and beck depression index(BDI) were done respectively. Mild to severe BDI were seen in 26.2%(52 patients) of the whole patients. A BDI mean score of female patients was 8.8±7.5 which was higher than that of male patients(5.6±6.6), the difference observed being statistically significant(p<0.001). In the acoustic analysis, the score of sent_duration parameter was increasing in the patients with depression, which was significantly higher than the score of the patients without depression(p<0.05). In the addition, the scores of VHI and RSI were higher in the patients with depression(p<0.001). Our findings suggest that the prevalence of depression in patients with voice disorders is related to female, speaking velocity, and self-questionnaire. This result can be used for psychologically based approach to therapy.
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강영애(Kang, Young Ae),박현영(Park, Hyun Young),구본석(Koo, Bon Seok) 한국음성학회 2013 말소리와 음성과학 Vol.5 No.4
The acoustic analysis of diadochokinesis(DDK) has been used to evaluate dysarthria. However, there has not been an automatic method to evaluate dysarthria. The aim of this study was to introduce a new automated program to measure DDK tasks and to apply this to clinical patients with idiopathic Parkinson"s disease(IPD). Fourty-seven patients with IPD and a healthy control group of twenty participants were selected with every DDK task recorded three times. Twenty-five acoustic parameters in the program were developed. The relevant parameters were times of DDK, pitch related parameters, intensity parameters which were analyzed by 2-way ANOVA. Significant differences between the groups were found in the times of DDK, pitch related parameters, and intensity parameters. The findings indicated that the pitch of control group was more stable than that of the IPD. Even though the patients with IPD had a higher intensity value, this phenomenon was caused by the weakness of the IPD group who could not control their speech with a breath.
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사례 적용 Praat 기반 CSL 대체 자동화 음성분석 프로그램
강영애,장재원,구본석,Kang, Young Ae,Chang, Jae Won,Koo, Bon Seok 대한후두음성언어의학회 2021 대한후두음성언어의학회지 Vol.32 No.2
There are a number of voice analysis programs around the world. Domestic voice analysis is performed by relying heavily on specific commercial program. We intend to develop coding for voice analysis using Praat and apply it to clinical practice. This study consisted of Experiment 1 and Experiment 2. Experiment 1 was the development of automated voice analysis coding based on Praat. The coding was largely divided into a recording, an analysis, and a storage section. Experiment 2 was applied to the voice analysis of 2 male patients pre- and post-operation with this coding. The analysis parameters of this coding provided 26 parameters for vowel /a/, nine parameters for sentence analysis, and a total of 4 parameters for voice range profile analysis. In two male patients, the pitch and the intensity increased, the voice quality improved, and the sentence length decreased after surgery. The coding was well made, so the output was good in real time. The code is automated as much as possible to block manual errors and increases convenience and efficiency by generating the result sheet in real time.
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강영애(Kang, Young Ae),장재원(Chang, Jae Won),구본석(Koo, Bon Seok) 한국음성학회 2016 말소리와 음성과학 Vol.8 No.3
The present study examined the change of aerodynamic features after laryngomicrosurgery in patients with vocal polyps. Aerodynamic evaluation was performed in thirty-nine patients (15 males and 24 females) one week before surgery and four weeks after surgery. Evaluation protocols of vital capacity, maximum sustained phonation(MXPH), and voicing efficiency(VOFT) were used to collect 29 phonatory aerodynamic measures, requiring voice with a comfortable pitch and loudness. Statistically significant changes were found for phonation time and airflow values in the MXPH protocol, while changes were also found for airflow values, subglottal pressure values and acoustic resistance values in the VOFT protocol. Although phonation time was increased in both male and female patients, gender-dependent changes were found in airflow measurements. Men’s phonation time increased with no difference in airflow rate, but women’s phonation time increased with decreased airflow rate and lower subglottal pressure. The changes of aerodynamic features may be affected by women"s self-perceived change for vocal attitude, which was reducing sense of vocal effort after surgery.
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강영애 ( Young Ae Kang ),임재준 ( Jae Joon Yim ),김영환 ( Young Whan Kim ),한성구 ( Sung Koo Han ),심영수 ( Young Soo Shim ),유철규 ( Chul Gyu Yoo ) 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.58 No.1
A-67-year old man was hospitalized due to fever, cough and dyspnea upon exertion, and was treated with intravenous antibiotics. During the hospital course he presented with weakness in his low extremities. The laboratory tests showed an elevated CK level
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