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정소영,한택희,한금호,강영종,Chung. So-Young,Han. Taek-Hee,Han. Keum-Ho,Kang. Young-Jong 한국방재학회 2007 한국방재학회 학술발표대회논문집 Vol.2007 No.1
Stress concentration have a effect on commission of structures and sometimes it cause the fracture of structures. Stress concentration is appeared where have a sudden section change like pipe connections. So stress concentration is a potent influence at pipe connentions. This paper make a study of pipe connections to alleviate stress concentration, and propose the stress concentration alleviation method that will make better efficient pipe system and will have a good effect on economic, social aspect.
광선각화증에서 비정형세포층의 두께 및 조직학적 아형에 따른 Blue Light를 이용한 ALA-PDT의 치료효과 비교
정소영 ( So Young Jung ),홍순권 ( Soon Kwon Hong ),서종근 ( Jong Keun Seo ),성호석 ( Ho Suk Sung ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.2
Background: Precancerous diseases of the skin such as actinic keratosis (AK), Bowen disease (BD) and skin cancer, i.e. basal cell carcinoma (BCC), are treated successfully with photodynamic therapy (PDT). In BCC, the therapeutic effect of PDT was different according to the subtypes. However, there has been no study on the response to PDT in the thickness of atypical cell layer and the histopathologic subtype of AK. Objective: We evaluated the responses to PDT using a topical 20% aminolevulinic acid (ALA) solution and a blue light, according to the thickness of atypical cell layer in AK. Further, we assessed the therapeutic response in the histopathologic subtypes of AK. Methods: There were a total of 29 AK lesions from 20 patients enrolled in the study. The lesions were incubated with a topical 20% ALA solution for 2 hours and were exposed to blue light (417±5 nm) with 10 J/cm2. They were treated 2 times at the 4 weeks intervals. The evaluation of the response to ALA-PDT was done by the skin biopsy at the post 8 weeks period from the last treatment. The therapeutic response was assessed into 3 grades (complete remission, partial remission, no response). The relationship between the therapeutic response and the thickness of atypical cell layer was evaluated. The thickness of atypical cell layer was measured from the most superficial aspect of the Malpighian layer to the tip of rete ridge. In addition, we evaluated the therapeutic effects according to the histopathologic subtypes. Results: The thickness of atypical cell layer were 0.0327±0.0087 mm in complete remission (CR) group, 0.1253±0.1128 mm in partial remission (PR) group and 0.1485±0.1973 mm in no response (NR) group (p=.0206). CR were achieved in 100% (4/4) of atrophic type, 43.75% (7/16) of hypertrophic type and 0% (0/9) of bowenoid type in AK. The response of ALA-PDT was the best in atrophic type (p=.032) and the lowest in bowenoid type (p=.0051) as compared with other subtypes. Conclusion: The responses to ALA-PDT were different in the thickness of atypical cell layer and it was statistically significant. The therapeutic effect was the best in the atrophic type of AK. (Korean J Dermatol 2012;50(2):101~105)
Suction-assisted Cartilage Shaver로 치료한 다발성 피지낭종
서종근 ( Jong Keun Seo ),정소영 ( So Young Jung ),홍순권 ( Soon Kwon Hong ),이드보라 ( Deborah Lee ),성호석 ( Ho Suck Sung ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.8
Steatocystoma multiplex is a rare autosomal-dominant disorder characterized by asymptomatic multiple, skin-colored to yellowish nodules on the trunk, proximal extremities, and axillae. Although surgical excision is the most effective method, treatment is difficult when lesions occur in multiple numbers. Therefore, various treatments such as CO2 laser therapy, needle aspiration, and oral isotretinoin have been attempted, but results are variable. A 37-year-old man presented with multiple skin-colored subcutaneous nodules on the abdomen and both axillae. A histopathological examination was consistent with steatocystoma multiplex. The lesions were removed by dermal shaving with a suction-assisted cartilage shaver. It was an effective therapeutic method for multiple lesions with no significant adverse events. Herein, we report a case of steatocystoma multiplex treated with a suction-assisted cartilage shaver. (Korean J Dermatol 2011;49(8):735∼737)
여드름 환자에서 Adapalene-benzoyl Peroxide MLE (Multi Lamellar Emulsion) 고정용량 복합제제 요법의 치료 효과에 대한 연구
박소희 ( So Hee Park ),박인호 ( In Ho Park ),황성환 ( Sung Hwan Hwang ),정소영 ( So Young Jung ),왕한영 ( Han Young Wang ),김효진 ( Hyojin Kim ),김종욱 ( Jong Uk Kim ),설정은 ( Jung Eun Seol ) 대한피부과학회 2020 대한피부과학회지 Vol.58 No.6
Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. Adapalene-benzoyl peroxide gel has been proven to be effective in the treatment of both inflammatory and comedonal acne. However, skin irritation characterized by erythema, scaling, and dryness may occur with the use of this formula. Objective: This study aimed to investigate the effects and safety of a new formulation of adpalene-benzoyl peroxide in combination with multi-lamellar emulsion (MLE) for acne treatment. Methods: All patients were treated with adapalene-benzoyl peroxide with MLE once daily for 12 weeks on acne lesions. The subjects visited the hospital at baseline, 2 weeks, 4 weeks, 8 weeks, and 12 weeks, and clinical effects, patient satisfaction, and adverse effects were estimated. The severity of adverse effects was measured on a 4-point scale. Results: A total of 30 subjects were enrolled. The number of lesions decreased significantly from 20.2 to 7.8 (p<0.0001) after treatment. Investigator’s global assessment showed almost clear, and patient satisfaction increased from 3.57 to 4.13. The subjects had adverse effects such as tingling sensation (83.3%), scales (80.0%), erythema (63.3%), and dryness (63.3%). Severity of adverse effects had 1 point on average. Additionally, transepidermal water loss was found to be decreased. Conclusion: This study suggests that adapalene-benzoyl peroxide with MLE is effective for treating acne lesions and shows high patient satisfaction. Hence, this new combination could be a safe and well-tolerated option for acne treatment. (Korean J Dermatol 2020;58(6):382∼388)
서종근 ( Jong Keun Seo ),정소영 ( So Young Jung ),전지승 ( Ji Sung Chun ),심현수 ( Hyun Soo Sim ),이드보라 ( Deborah Lee ),성호석 ( Ho Suck Sung ) 대한피부과학회 2010 大韓皮膚科學會誌 Vol.48 No.12
Tufted angioma is a rare, slow-growing, benign, vascular tumor that usually occurs in children. It appeared as an erythematous to red-brown, indurated papule on the trunk or neck. Histopathologic examination shows multiple capillary lobules in a cannon ball appearance scattered throughout the dermis. We present here a 32-year-old woman with multiple annular lesions on her right thigh, which started as red papules and they progressed with annular extension and central regression for 3 years. The histopathologic findings were compatible with tufted angioma. The lesions were treated with 3 sessions of sclerotherapy. We report here on an unusual tufted angioma that occurred as multiple lesions which showed annular extension with central regression. (Korean J Dermatol 2010;48(12):1121∼1124)