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황련해독탕약침(黃連解毒湯藥針)을 이용한 흉부상열감(胸部上熱感) 치험(治驗) 2례(例)
김종욱,이윤재,임은경,신선호,김동웅,홍석훈,주종천,조권일,Kim, Jong-Uk,Lee, Yun-Jae,Rhim, Eun-Kyung,Shin, Sun-Ho,Kim, Dong-Woung,Hong, Seok-Hoon,Joo, Jong-Cheon,Cho, Gwon-Il 대한약침학회 2003 Journal of pharmacopuncture Vol.6 No.2
The purpose of this study is to evaluate the clinical effect of Hwangryunhaedok-tang Herbal-Acupuncture. Hwangryunhaedok-tang is used in all heating diseases. Chest Heating Sensation is a unique concept in Oriental Medicine. So we applied Hwangryunhaedok-tang Herbal-Acupuncture to treat the Chest Heating Sensation. We used DITI(Digital Infrared Thermographic Imaging) to estimate the temperatures of chest surface for the outcome assessment. We came to know that the chest surface temperatures were all reduced in both cases after Herbal-Acupuncture treatment. The reduced average temperature was $1.5^{\circ}C$ in case 1 and $0.9^{\circ}C$ in case 2. The above result indicates that Hwungryunhaedok-tang Herbal-Acupuncture treatment has an effect on Chest Heating Sensation, thus continuous Hwangryunhaedok-tang Herbal-Acupuncture study will be needed for more clinical applications.
백두옹탕(白頭翁湯)의 대장암 세포주 HCT-116 항암효과와 세포자멸사에 관한 연구
김종욱,문구,박찬희,이정한,지혜민,Kim, Jong-Uk,Moon, Goo,Park, Chan-Ny,Lee, Jeong-Han,Ji, Hye-Min 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.2
Objectives : To investigate the anti-cancer effect of Baekduong-tang(BDOT) against cancer cells, the signaling pathway of apoptosis was explored in human colon cancer cells. Materials and Methods : Human colon cancer cell lines, including HT-29 and HCT-116 cells, were used. Cell viability was measured by MTT assay. Apoptosis was determined by DAPI nuclei staining and flow cytometry in HCT-116 cells treated with 0.25 mg/$m{\ell}$ Baekduong-tang for 48 hrs. Results : Baekduong-tang induced the apoptosis of p53 positive HCT-116 cells with G2/M phase arrest. Treatment with Baekduong-tang led to increased expression and phosphorylation of p53 and decreased expression of CDK2 and CDK6 in HCT-116 cells. It also activated caspase-3 through caspase-10 and caspase-9 activation. Finally, Baekduong-tang induced production $H_2O_2$, superoxide anion ($O_2^-$) and NO and modulated proteins expression including SOD, NOS, Bax and Bcl-2. Conclusions : These results indicate Baekduong-tang induces apoptotic death of HCT-116 cells through G2/M phase arrest and disturbance of intracellular redox status in a p53-dependent manner.
김종욱,Kim, Jong-Uk 한국식품연구원 2008 한맛한얼 Vol.1 No.2
식품공전에는 커피를 다류의 한 품목으로 규정하고 있으며 '커피의 원두를 가공한 것이거나 또는 이에 식품, 식품첨가물을 더한 기호성 식품을 말한다' 라고 정의하고 있다. 주원료 성분배합기준에 의한 커피의 분류는 아래와 같다.
김종욱,Kim, Jong-Uk 한국방위산업진흥회 1992 國防과 技術 Vol.- No.163
선진국의 유도탄 고체 추진기관의 연구 개발 동향 파악은 우리의 유도탄 추진기관 연구개발의 좌표확인과 나아갈 방향을 설정하는데 대단히 중요합니다. 이 글에서는 유도탄에 사용되는 고체 추진기관에 대한 세계적 연구 동향을 분석하였습니다 연구 동향은 추진시스템과 추진기관 부시스템 및 부품 2가지 부분으로 나누어 살펴보았습니다. 추진시스템은 기존의 로켓과는 다른 닥티드로켓/램젯, 펄스 모타등의 새로운 추진시스템의 연구동향을 분석하였으며, 기존 고체 로켓 모타부품의 연구개발 및 동향을 기술하였습니다
행간(行間)(LR2) 전침자극(電鍼刺戟)이 적외선(赤外線) 체열진단상(體熱診斷上) 안면부(顔面部) 온도변화(溫度變化)에 미치는 영향(影響)
김종욱,최성용,진경선,황우준,민상준,이순호,이상룡,Kim, Jong-uk,Choi, Sung-yong,Jin, Kyong-son,Hwang, Woo-jun,Min, Sang-jun,Lee, Sun-ho,Lee, Sang-ryong 대한침구의학회 2004 대한침구의학회지 Vol.21 No.1
Objective: Purpose of this study was to examine the effect of electroacupuncture(EA) at Xingjian(LR2) as 'Fire(火)' point of The Leg Absolute Um Liver Meridan(足厥陰肝經 : Chok-Kworum-Kan-Kyong) on the facial thermal change. Methods: Subjects of this study were 15 patients with upperpart(includes head and facial part) fever of human body and two examinations were carried out in each other day. We divided cases of two examinations into two groups. One is experimental group(N=15) that was carried out electroacupuncture stimulation at Xingjian(LR2), the other is control group(N=15) which was carried out electroacupuncture stimulation at optional point(in space between 1st and 2nd fingers) except acupuncture points of 12 meridians. We took the temperature of fixed areas on face by digital infrared thermal image(D.I.T.I.) before and after electroacupuncture stimulation. Those fixed areas on face that was taken temperature are Jingming(BL1), Sibai(ST2), Dicang(ST4), Indang, Shuigou(GV26), Chengjiang(CV24) areas. In cases of temperature of Jingming(BL1), Sibai(ST2), Dicang(ST4) areas, we applied each mean of left and right temperature to statical analysis. Results: In the group of electroacupuncture stimulation at Xingjian(LR2), temperature of every fixed areas on face fell: Jingming(BL1) area's ${\Delta}T=-0.7007{\pm}0.78642$, Sibai(ST2) area's ${\Delta}T=-0.6280{\pm}0.56439$, Dicang(ST4) area's ${\Delta}T=-0.5940{\pm}0.60179$, Indang area's ${\Delta}T=-0.7200{\pm}0.64515$, Shuigou(GV26) area's ${\Delta}T=-0.6160{\pm}0.80487$, Chengjiang(CV24) area's ${\Delta}T=-0.5627{\pm}0.72615$. In Xingjian(LR2) electroacupuncture group, each temperature of Jingming(BL1), Sibai(ST2), Indang areas showed a drop significantly in comparison with control group (p<0.05). But each temperature of Dicang(ST4), Shuigou(GV26), Chengjiang(CV24) areas did not showed a drop significantly in comparison with control group(p>0.05). Conclusions: The results mentioned above showed that electroacupuncture stimulation at Xingjian(LR2) significantly decreased the temperature on face of patients with upperpart fever of human body. In Xingjian(LR2) electroacupuncture group, especially temperature of upper part of face includes eye, cheekbone, forehead regions showed a drop significantly in comparison with control group.
서태평양 지판소멸대의 해저열수분출구에서 관찰되는 황동위원소 조성변화: 열수 생성의 다양성과 마그마의 역할
김종욱,문재운,이경용,이인성,Kim, Jong-Uk,Moon, Jai-Woon,Lee, Kyeong-Yong,Lee, In-Sung 대한자원환경지질학회 2012 자원환경지질 Vol.45 No.2
해저열수시스템은 중앙해령이나 후열도확장대와 같은 해저화산대를 따라 생성된다. 해저열수시스템은 지각-맨틀과 해양의 에너지와 물질이 교환되는 장으로 이를 통해 지각과 해수의 조성이 변화하며, 해저면에 열수분출구를 침전시켜 열수생태계를 형성하고 금속광상이 만들어진다. 상대적으로 단순한 중앙해령과 달리 지판소멸지역의 해저열수시스템은 섭입되는 물질의 재순환과정에서 다양한 특성이 나타난다. 황동위원소 조성은 이러한 열수시스템의 다양성을 평가하는데 유용하다. 이 논문에서는 서태평양의 지판소멸대에서 발견된 열수분출 지역에서 채취된 열수분출구 시료의 황동위원소 조성변화를 살펴보고 이들 환경에서 열수생성의 다양성을 일으키는 요인을 고찰하였다. 지판소멸대의 열수분출구는 황화광물과 황산염광물 모두 낮은 황동위원소 조성을 갖는 것이 특징이며, 이는 마그마로부터 공급된 $SO_2$ 기체의 유입으로 해석된다. 황동위원소 조성 변화를 포함한 열수시스템의 다양성은 열수시스템 생성과정에서 마그마의 적극적인 역할을 지시한다. Seafloor hydrothermal system occurs along the volcanic mid-ocean ridge, back-arc spreading center, and other submarine volcanic regions. The hydrothermal system is one of the fundamental processes controlling the transfer of energy and matter between crust/mantle and ocean; it forms hydrothermal vents where various deepsea biological communities are inhabited and precipitates metal sulfide deposits. Hydrothermal systems at convergence plate boundaries show diverse geochemical properties due to recycle of subducted material compared to simple systems at mid-ocean ridges. Sulfur isotopes can be used to evaluate such diversity in generation and evolution of hydrothermal system. In this paper, we review the sulfur isotope composition and geochemistry of hydrothermal precipitates sampled from several hydrothermal vents in the divergent plate boundaries in the western Pacific region. Both sulfide and sulfate minerals of the hydrothermal vents in the arc and backarc tectonic settings commonly show low sulfur isotope compositions, which can be attributed to input of magmatic $SO_2$ gas. Diversity in geochemistry of hydrothermal system suggests an active role of magma in the formation of seafloor hydrothermal system.
척추관내 인대 골화증 6례에 대한 임상적 고찰 -후종인대 골화증(OPLL) 3례 및 황색인대 골화증(OLF) 3례-
김종욱,최성용,황우준,이순호,유인식,Kim, Jong-uk,Choi, Sung-yong,Hwang, Woo-jun,Lee, Sun-ho,Yoo, In-sik 대한침구의학회 2004 대한침구의학회지 Vol.21 No.6
Objective : Ossification of ligaments within spinal canal, i.e., OPLL and OLF, is uncommon clinical entity as a cause of the progressive compression myelopathy or radiculopathy. More and more cases being reported in the field of occidental medicine, but very few cases have been reported in the field of oriental medicine. The purpose of this study is to report on oriental medical approaches to OPLL and OLF. Methods : Subjects of this study are 3 cases of OPLL and 3 cases of OLF who visited Won-kwang oriental medical hospital(Dept. of acupuncture and Moxibustion) from May, 2002 to October, 2003. These patients undergo oriental medical treatment such as acupuncture, cupping, Bee-Venom therapy and herbal medication and so on. We made a comparison JOA scores between before treatment and after treatment and we evaluated results of treatment. Results : The results of treatment in these six cases are as follows ; One case was evaluated 'Excellent', one case was evaluated 'Good', two cases were evaluated 'Fair' and two cases were evaluated 'Failure'. One of these cases had a surgical operation after discharge from this hospital. Conclusions : After oriental medical care for these cases, there are some improvements such as decrease of pains, relief of myelopathy etc. But, it had little effect on some cases, therefore we considered that more special study to find various and effective methods of oriental medical treatment for these diseases should be made.